Clinical trials: Asthma COPD
Asthma, Chronic Obstructive Pulmonary Disease
Clinic Versus Home Spirometry
The study aims to assess the differences between spirometry performed with the NuvoAir Air Next spirometer in the clinic setting with both direct and virtual supervision via a video call, and in the home setting with virtual…
- Trial name
- COMPAIR (NCT05219773)
- Testing
- NuvoAir Air Next spirometer
- Where
- 3 sites in United Kingdom
- Volunteers
- 68 people
- Sponsor
- University of Nottingham
Acute Respiratory Disease, COPD Exacerbation Acute
Study of Hospitalised Patients With Acute Respiratory Conditions
The goal of this observational study is to learn about the short- and long-term outcomes of people admitted to hospital with an acute respiratory condition, including exacerbations of chronic lung disease, and to understand…
- Conditions
- Acute Respiratory Disease, COPD Exacerbation Acute, Asthma, Pneumonia
- Trial name
- CHESTY (NCT05095090)
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Asthma, Bronchitis
Tucson Epidemiology Study of Chronic Obstructive Lung Diseases
To determine the natural history, etiology, and interrelationships of emphysema, chronic bronchitis, asthma, and related airways obstructive diseases.
- Conditions
- Asthma, Bronchitis, Emphysema, Lung Diseases, Obstructive
- Trial name
- NCT00005279
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Asthma, Chronic Obstructive Pulmonary Disease
Evaluation of the Efficacy of Respicure® (Resveratrol / Quercetin) in the Management of Respiratory Conditions Including Asthma,COPD and Long COVID.
Interventional, Prospective, National, Multicentre, Randomised, Open-label, Controlled Clinical Study Comparing Two Parallel Groups, One Control Arm (Standard Treatment) Versus Intervention Arm (Standard Treatment + Study…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease, Long COVID
- Trial name
- NCT05601180
- Testing
- Respicure®, Standard of care
- Where
- 8 sites in Algeria
- Volunteers
- 402 people
- Sponsor
- Beker Laboratories
Asthma Bronchiale, COPD
Bronchodilator Response in COPD and Asthma: Correlation Between Spirometry, IOS Indices, and Dyspnea Relief
A bronchodilator reversibility test is widely used in the diagnosis and management of obstructive lung diseases. Bronchodilators relieve symptoms in asthma and COPD.
- Conditions
- Asthma Bronchiale, COPD, Bronchodilation, Spirometry
- Trial name
- NCT07364188
- Testing
- Bronchodilator
- Volunteers
- 120 people
- Sponsor
- Allergi- og Lungeklinikken, Elsinore
Asthma, COPD
Prospective evAluatIon foR Inhalation Devices Study
ASTHMA: Asthma is a chronic inflammatory disorder of the airways in which many different types of cells, and various cellular components.
- Trial name
- PAIR (NCT01800994)
- Where
- 6 sites in Greece
- Volunteers
- 750 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Dyspnea, Chronic Obstructive Pulmonary Disease
The Increase of Lung Capacity Using the Lung Master (Pulmonary Exerciser)
Investigators are studying how a device called The Lung Master device can help people breathe better. The investigational device increases the amount of air our lungs can hold, which is important for overall lung health.
- Conditions
- Dyspnea, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT06524856
- Testing
- Lung Master (Pulmonary Exerciser)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Dyspnea, Heart Failure
Dyspnea and Biomarkers in a Prehospital Setting
In patients presenting with acute dyspnea in a pre-hospital setting, the early and correct diagnosis may present a significant clinical challenge.
- Conditions
- Dyspnea, Heart Failure, Asthma, COPD
- Trial name
- NCT00878475
- Where
- Slovenia
- Volunteers
- 546 people
- Sponsor
- Community Healthcare Center dr. Adolf Drolc Maribor (HCM)
Pulmonary Disease, Chronic Obstructive, Asthma
Efficacy and Safety of 4 Weeks Treatment With Inhaled BI 1744 CL in Patients With COPD.
The primary objective of this study is to determine the optimum dose(s) of BI 1744 CL inhalation solution delivered by the Respimat® inhaler for four weeks in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT00452400
- Testing
- BI 1744CL
- Where
- 42 sites in United States, Canada and 2 more
- Volunteers
- 409 people
- Sponsor
- Boehringer Ingelheim
Asthma, COPD
Observational Study of Obstructive Lung Disease (NOVELTY)
The NOVEL Observational longiTudinal studY (NOVELTY) is an observational study of obstructive lung disease and is a multi-country, multi-centre, prospective, longitudinal cohort study which will recruit patients with a diagnosis…
- Conditions
- Asthma, COPD, Chronic Obstructive Pulmonary Disease
- Trial name
- NOVELTY (NCT02760329)
- Testing
- Blood draw, Urine, Lung function measurements
- Where
- 331 sites in United States, Argentina and 17 more
- Volunteers
- 12,255 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease, Bronchiectasis
Reducing Chronic Breathlessness in Adults by Following a Self-guided, Internet Based Supportive Intervention (SELF-BREATHE)
Background: Some health conditions make breathing difficult and uncomfortable. When this happens every day, it is called chronic breathlessness.
- Conditions
- Chronic Obstructive Pulmonary Disease, Bronchiectasis, Interstitial Lung Disease, Lung Cancer
- Trial name
- SELF-BREATHE (NCT06326957)
- Testing
- SELF-BREATHE
- Where
- United Kingdom
- Volunteers
- 246 people
- Sponsor
- King's College Hospital NHS Trust
COPD, Emphysema, Asthma COPD Overlap, Emphysema
Site and Mechanism(s) of Expiratory Airflow Limitation in COPD, Emphysema and Asthma-COPD Overlap
The purpose of this cross-sectional, observational study is to evaluate the site and mechanism(s) for expiratory airflow limitation in chronic, treated, current or former smokers (>15 pack years) with COPD, Emphysema, and…
- Trial name
- NCT03263130
- Testing
- As above: diagnosis: COPD, Emphysema, Asthma-COPD Overlap
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gelb, Arthur F., M.D.
Chronic Obstructive Respiratory Diseases
Development of Predictive Biomarkers for the Diagnosis and Treatment of Asthma and COPD in Vietnam.
According to World Health Organization (WHO), non-communicable diseases account for 70% of global mortality. Chronic Respiratory Disease (CRD) affects more than one billion people and is the third leading cause of annual death of…
- Trial name
- NCT04232579
- Testing
- Therapeutic strategy
- Where
- 2 sites in Belgium, Vietnam
- Volunteers
- 600 people
- Sponsor
- Olivier Michel
Asthma, COPD
The Effect of FP-025, on Allergen-induced Airway Responses in Mild Eosinophilic House Dust Mite (HDM)-Allergic Asthma.
This study is a Phase IIa, randomized, placebo-controlled, double-blind, 2-way crossover, 2-center (conducted in EU; The Netherlands) study in male and female subjects with stable, mild HDM-allergic asthma.
- Trial name
- NCT03858686
- Testing
- FP-025 capsules
- Where
- 2 sites in Netherlands
- Volunteers
- 27 people
- Sponsor
- Foresee Pharmaceuticals Co., Ltd.
Asthma, Chronic Obstructive Pulmonary Disease
Effectiveness of Influenza Vaccine Reminder Systems
Influenza disease causes significant morbidity and mortality in the Unites States each year. Although influenza can cause morbidity in otherwise healthy individuals, adults with chronic lung disease have significantly increased…
- Trial name
- NCT01852656
- Testing
- Postcard and IVR Reminder Group, Postcard Only Reminder Group, IVR Only Reminder Group
- Where
- United States
- Volunteers
- 12,255 people
- Sponsor
- Kaiser Permanente
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
HR-lowering Efficacy and Respiratory Safety of Ivabradine in Patients With Obstructive Airway Disease
The purpose of this study is to investigate heart rate lowering efficacy and respiratory safety of ivabradine in patients with asthma and COPD.
- Trial name
- NCT01365286
- Testing
- Ivabradine (Procoralan)
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Lodz
Asthma, COPD
Teaching Use of Respiratory Inhalers (TURI)
The purpose of this study is to evaluate the feasibility of enrolling and randomizing patients into one of two educational interventions to teach appropriate respiratory inhaler technique and to collect preliminary estimates of…
- Trial name
- TURI (NCT01456494)
- Testing
- Brief Intervention, Teach-to-Goal Education
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Chicago
Cancer, COPD
SELF-BREATHE RCT for Chronic Breathlessness
A feasibility RCT comprising two groups: 1. Intervention (SELF-BREATHE in addition to standard NHS care) 2. Control group (standard / currently available NHS care)
- Conditions
- Cancer, COPD, Asthma, Bronchiectasis Adult
- Trial name
- NCT04574050
- Testing
- SELF-BREATHE
- Where
- United Kingdom
- Volunteers
- 52 people
- Sponsor
- King's College Hospital NHS Trust
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Canadian Consortium on Airway Mucus Occlusions in Asthma, COPD and Chronic Cough
Chronic lung diseases affect one in five Canadians, causing symptoms such as cough, breathlessness, and wheeze. Despite advancements in medical care, these conditions not only impact individuals and their close circles but also…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease (COPD), Chronic Cough (CC)
- Trial name
- CANMuc (NCT06858748)
- Testing
- Observational
- Where
- 7 sites in Canada
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- McMaster University
Asthma, COPD
Small Airway Obstruction in Asthma, COPD, ACOS
This study was designed as retrospective chart review to test our hypothesis whether there are the differences in inflammatory and anti-inflammatory mediators between asthmatic and ACOS patients with small airway obstruction, and…
- Conditions
- Asthma, COPD, Asthma-COPD Overlap Syndrome
- Trial name
- NCT03423693
- Testing
- No any intervention
- Where
- Thailand
- Volunteers
- 230 people
- Sponsor
- Mahidol University