Clinical trials: Asthma Childhood
Asthma in Children
Forced Oscillations Technique During a Metacholine Test in Children
Asthma is the most common chronic lung disease in children. It affects more than 1 in 10 children in France. The methacholine bronchial challenge test (MBT) is indicated to assess the probability of asthma suggested by clinical…
- Trial name
- TPM AOS (NCT05734261)
- Testing
- Airway Oscillation System
- Where
- France
- Volunteers
- 112 people
- Sponsor
- University Hospital, Montpellier
Asthma in Children
Fear of COVID-19 and Physical Activity in Children With Asthma During the Covid Period
Social isolation rules applied to prevent and control COVID-19 disease reduce cross-infection, exposure to more allergens in the home environment, reducing hospital admissions by avoiding contamination, asthma control, fear of…
- Trial name
- NCT05220488
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bartın Unıversity
Asthma in Children, Asthma
Dynamics of the Upper and Lower Airway Respiratory Microbiomes Associated With Severe Infant Asthma
Nature of potential dysbiosis, interrelation of the different microbiomes of the respiratory tract, and potential role of the immune system in the pathogenesis of severe asthma in infants, and its evolution under treatment.
- Trial name
- Microbiosthme (NCT06044051)
- Testing
- Blood sample, Expectoration, Nasopharyngeal swab
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Rouen
Persistent Asthma
Effect of Vitamin D Supplementation on the Control of Asthma in Children at a South African Academic Hospital
The aim of this randomized double-blind placebo controlled study is to assess whether vitamin D supplementation will improve control in South African children with persistent asthma at an academic hospital.
- Trial name
- NCT02053402
- Testing
- Vitamin D
- Where
- South Africa
- Volunteers
- 100 people
- Sponsor
- University of Limpopo
Pediatric Asthma, Uncontrolled Asthma
Systems Pharmacology Approach to Uncontrolled Pediatric Asthma
Background: Asthma is a heterogeneous respiratory disease and the most common chronic disease in children. A small subset of children has continuous poor asthma control despite appropriate adherence to asthma medication.
- Trial name
- NCT04865575
- Where
- 6 sites in Germany, Netherlands and 3 more
- Volunteers
- 145 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Asthma in Children, Influenza Vaccine
Influenza Vaccine in Children With Asthma
The occurence of influenza can be a factor of imbalance of asthma. Asthma patients are recommended for annual influenza vaccination .
- Conditions
- Asthma in Children, Influenza Vaccine, Immunization Coverage
- Trial name
- VAGA (NCT04086628)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Central Hospital, Nancy, France
Childhood Asthma
Changes in the Lung Clearance Index in Pediatric Patients With Asthma
The multiple breath washout (MBW) is one of pulmonary function test that displays flow and gas concentration plotted against time, and shows an exponential decay in end-tidal gas concentration (washout curve).
- Trial name
- NCT02678949
- Testing
- Inhaled Fluticasone 50 mcg/twice day, Inhaled Fluticasone 100 mcg/twice day, Inhaled Albuterol
- Where
- Mexico
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Wheezy Bronchitis, Asthmatic Bronchitis
Efficacy of Intermittent Tiotropium in Early Childhood Wheezing
This study evaluates the effect of intermittent tiotropium bromide and salbutamol as needed versus intermittent fluticasone propionate and salbutamol as needed, or solely, salbutamol as needed on episode-free days in infants and…
- Conditions
- Wheezy Bronchitis, Asthmatic Bronchitis, Wheezing, Obstruction Airway
- Trial name
- NCT03199976
- Testing
- Tiotropium Bromide, Fluticasone Propionate, Salbutamol
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Helsinki University Central Hospital
Asthma in Children
Association Between Household Health Behaviors and Asthma in Children
This study plan to study the association between household health behavior (cleaning habits) and children's asthma. In addition, reconfirm the health effects of indoor environmental exposure to phthalates plasticizers, mite…
- Trial name
- ABHHBaAiC (NCT04565964)
- Testing
- change the health behaviors to clean indoor environment
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Lung Diseases, Asthma
Nutrition in Pregnancy, Birth Weight, and Childhood Asthma
To evaluate the role of maternal diet and birth weight in the etiology of childhood asthma and other allergic disorders.
- Trial name
- NCT00006404
- Sponsor
- Harvard Pilgrim Health Care
Childhood Asthma
STudy of Asthma Adherence Reminders
To determine whether electronic adherence monitoring with feedback and reminder alarms can improve adherence and health outcomes in childhood asthma.
- Trial name
- STAAR (NCT02451709)
- Testing
- Activated Smartinhaler or Smartturbo, Feedback of adherence data, Deactivated Smartinhaler or Smartturbo
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Asthma in Children
Determinants of Functional Capacity in Children With Asthma
The primary aim of this study is to compare the respiratory function, respiratory muscle strength, functional capacity, and lower extremity strength of children with asthma and healthy children in the same age group.
- Trial name
- NCT05963919
- Testing
- 6-minute walk test, Pulmonary function test, Respiratory muscle strength test
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Atlas University
Asthma
Use of Dexamethasone in Pediatric Asthma Exacerbations
The purpose of this study is to compare the efficacy of a single dose of dexamethasone vs. two doses of dexamethasone in mild and moderate asthma exacerbations pediatric patients.
- Trial name
- NCT02192827
- Testing
- Dexamethasone Sodium Phosphate Injection
- Where
- United States
- Volunteers
- 318 people
- Sponsor
- University at Buffalo
Asthma
A Study of Depemokimab in Participants of 6 to 11 Years of Age
This study is aimed at assessing depemokimab as an add-on medicine for the treatment of asthma with type-2 inflammation in participants of 6 to 11 years of age.
- Trial name
- GLIDE (NCT07671001)
- Testing
- Depemokimab
- Where
- 3 sites in United States
- Volunteers
- 34 people
- Sponsor
- GlaxoSmithKline
Asthma in Children
Telehealth Education for Asthma Connecting Hospital and Home
The goal of this study is to evaluate the feasibility, acceptability, and preliminary efficacy of a technology-enhanced educational intervention for caregivers and children who are hospitalized due to asthma.
- Trial name
- TEACHH (NCT04995692)
- Testing
- Telehealth Education for Asthma Connecting Hospital and Home, Standard Care (SC) Comparison Group
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Rochester
Childhood Asthma, Oxidative Stress
Urinary 8-isoprostane is Elevated in Acute Childhood Asthma
Oxidative stress is seen in children with asthma, but is hard to measure. The investigators exploring the utility of using a commercially available assay to measure oxidative stress in the urine in asthmatics.
- Trial name
- NCT01472471
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Stony Brook University
Asthma in Children
Asthma Navigator Intervention to Improve Health Equity in Children
The goal of this study is to improve health equity in children aged 5-16.9 years admitted to the PICU for asthma. The objectives are: To identify the factors related to differential experiences of asthma self-management To pilot…
- Trial name
- NCT06513832
- Testing
- The asthma navigator
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Emory University
Asthma, Childhood Asthma
Effect of Home Health Case Management on Asthma Morbidity
The objective of our program is to evaluate the effect of home health nurse intervention and education on hospital admissions, ER utilization and asthma control of Passport asthma patients.
- Trial name
- NCT01451944
- Testing
- education
- Where
- United States
- Sponsor
- University of Louisville
Pediatric Obesity, Asthma in Children
Steroid Metabolism in Obese and Non-Obese Pediatric Patients Hospitalized for Status Asthmaticus
Single center, open-label, non-randomized study to assess the pharmacokinetic profile of methylprednisolone in healthy children 2-20 years of age admitted for asthma exacerbation.
- Trial name
- NCT04874610
- Testing
- Methylprednisolone
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Duke University
Healthy
Preventive Medicine Study of Childhood Atopic Diseases
Under environmental intervention programs, to explore the associations between Environmental Tobacco Smoke (ETS) and changes of pulmonary function, cytokines and new-onset asthma between different groups.
- Trial name
- NCT00960596
- Testing
- Health promotion and health education for smoking habits
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital