Clinical trials: Asthma Childhood
Acute Otitis Media (AOM), Strep Pharyngitis
Evaluation of the Medentum Diagnostik Platform for Pediatric ENT Conditions and Asthma
This study evaluates the diagnostic performance, usability, and clinical utility of the Medentum Diagnostik platform, a multisensor device with integrated software and artificial intelligence, in pediatric patients with asthma…
- Conditions
- Acute Otitis Media (AOM), Strep Pharyngitis, Asthma Exacerbation, Pediatric Asthma
- Trial name
- NCT07500532
- Testing
- Diagnostik home-based platform: multisensor device, software application, and artificial-intelligence algorithms that predict diagnosis of AOM and strep pharyngitis, Diagnostik home-based platform: multisensor device, software application, and artificial-intelligence algorithms that predict diagnosis of wheeze/asthma exacerbation, Routine Asthma Management (in-person and telehealth visits)- Control Group
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Medentum Innovations
Asthma in Children
Early Administration of Steroids in the Ambulance Setting
Asthma is the most common chronic disease of childhood and is a leading cause of emergency medical treatment. For children experiencing an asthma exacerbation, emergency department (ED) guidelines recommend early systemic…
- Trial name
- EASI-AS-ODT (NCT03962894)
- Testing
- Prednisolone
- Where
- 7 sites in United States
- Volunteers
- 834 people
- Sponsor
- University of Florida
Asthma
Non-interventional Retrospective Multicenter Study of Patients With Bronchial Asthma During a Routine Visit to Out of Patients' Clinics
To assess asthma control in Russian patients according to the new criteria provided in the international guidelines and identify pharmacological approaches that provide a higher level of overall asthma control
- Trial name
- NIKA (NCT01273363)
- Where
- 12 sites in Russia
- Volunteers
- 1,000 people
- Sponsor
- AstraZeneca
Asthma in Children
BiPAP in Pediatric Moderate to Severe Asthma Randomized Control Trial
The goal of this clinical trial is to study if starting bi-level positive airway pressure (BiPAP), a mask that gives pressure to the lungs, works well for children in the emergency department with moderate to severe asthma…
- Trial name
- NCT05848115
- Testing
- Bi-level Positive Airway Pressure
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of Colorado, Denver
Asthma in Children, Atopy
Omalizumab Before Onset of Exacerbations
OBOE is a prospective, pilot, parallel group RCT with the overall aim of examining the effect of a single dose of anti-IgE (omalizumab) vs.
- Conditions
- Asthma in Children, Atopy, Viral Upper Respiratory Infection
- Trial name
- OBOE (NCT05332067)
- Testing
- Omalizumab
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Children's National Research Institute
Asthma
The Use of an Innovative Device for Therapeutic Adherence in Pediatric Asthma
The management of chronic diseases requires a constant monitoring of treatment adherence, in order to obtain an optimal disease control. However, this is often difficult to achieve, especially in pediatric age.
- Trial name
- NCT03788395
- Testing
- Symbicort Turbohaler plus Turbo+, Symbicort Turbohaler without Turbo+
- Where
- Italy
- Volunteers
- 18 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Asthma in Children
Tiotropium vs. Inhaled Corticosteroids in Children With Nonatopic Asthma Pilot Study (TioNAAP)
Most children with asthma have concurrent atopy (allergic inflammation), which is associated with an improved response to ICS. However, the absence of an atopic phenotype is associated with a poorer ICS response, leaving…
- Trial name
- TioNAAP (NCT04990167)
- Testing
- Tiotropium Bromide
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Nemours Children's Clinic
Allergy
Study of Indoor Air Pollutants and Their Impact in Children's Health and Wellbeing
The goal of this study is to identify and assess in real time the impact of the combined action of various types of air and dust pollutants within a classroom on children's health and quality of life, particularly regarding…
- Trial name
- SynAir-G2 (NCT07402200)
- Testing
- Standardized questionnaires, Lung function tests, Prick tests
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Asthma in Children
Oral Health Status of Asthmatic Children
This study aimed to investigate the dental caries experience, periodontal health and salivary properties of asthmatic and non-asthmatic children ⁄ adolescents.
- Trial name
- NCT04388098
- Testing
- Diagnosis of caries experience and periodontal health
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Trakya University
Asthma
Geographic Modeling of Traffic and Asthma Rates
This study surveys the parents/guardians about symptoms and diagnosis of asthma in kindergarten and first-grade students in 13 schools around the city of Anchorage, Alaska.
- Trial name
- NCT00041834
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Asthma in Children, Medication Adherence
Financial Incentives to Improve Asthma
The aim of this pilot randomised controlled trial is to assess the effectiveness of a short-term financial incentives intervention at bringing about behaviour change, namely short-medium term improvements in inhaled…
- Trial name
- FINA (NCT05322044)
- Testing
- Financial incentives
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Imperial College London
Asthma in Children, Atrial Fibrillation
Mitigating the Health Effects of Desert Dust Storms Using Exposure-Reduction Approaches
The MEDEA project is envisioned to provide the field-based evidence for the adoption of a strategic plan for mitigating the health effects of desert dust storm (DDS) events in South-Eastern Europe.
- Trial name
- MEDEA (NCT03503812)
- Testing
- Intervention (1) for outdoor exposure reduction - Asthma in Children, Intervention (2) for outdoor and indoor exposure reduction - Asthma in Children, Intervention (1) for outdoor exposure reduction - Atrial Fibrillation
- Where
- 3 sites in Cyprus, Greece and 1 more
- Volunteers
- 310 people
- Sponsor
- University of Cyprus
Childhood Asthma
A Community-based Participatory Research (CBPR) Intervention for Childhood Asthma Using Air Filters and Air Conditioners
The burden of childhood asthma is borne disproportionately by children living in poverty and in urban centers, many of whom are from communities of color and are at greater risk for environmental exposures.
- Trial name
- CAAA (NCT00839046)
- Testing
- Community Health Worker Intervention, Air Filter, Air Filter and Air Conditioner
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- University of Michigan
Asthma
Initiation of Chronic Asthma Care Regimens in the Pediatric Emergency Department
Hypothesis: Initiating chronic management treatment plans in conjunction with an asthma educational intervention in the pediatric Emergency Department (ED) with anti-inflammatory medication will result in an improvement of ED…
- Trial name
- IRUSBUPR0045 (NCT00388739)
- Testing
- Intervention: Budesonide, Usual care: albuterol + systemic steroids
- Where
- United States
- Sponsor
- Baylor College of Medicine
Healthy
Investigation of Lungfunction Normal Values in Children and Adolescent in Germany (Spirometry, Ultrasonic Pneumography and Exhaled NO)
Synopsis: LUNOKID-Study Investigation of Lung function Normal Values in Children and Adolescent in Germany For the diagnostic work-up of childhood airway diseases lungfunction measurements play an important role.
- Trial name
- LUNOKID-Studie (NCT00723619)
- Where
- Germany
- Volunteers
- 2,007 people, healthy volunteers welcome
- Sponsor
- Marien Hospital Wesel
Asthma, Lung Diseases
Adherence in the Childhood Asthma Management Program
To evaluate three adherence promoting interventions within the Childhood Asthma Management Program (CAMP), an eight center clinical trial that compared pediatric asthma therapies in children five to twelve years old.
- Trial name
- NCT00005705
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Childhood Asthma With Acute Exacerbation
Antibiotic Treatment of Recurrent Episodes of Asthma in Children
Copsac has discovered that asthmatic exacerbations are as closely linked to bacterial as to viral infection. The current study will examine whether treatment of asthmatic exacerbations with macrolide antibiotics - in the abscence…
- Trial name
- AB-studie (NCT01233297)
- Testing
- Azithromycin
- Where
- 2 sites in Denmark
- Volunteers
- 70 people
- Sponsor
- Copenhagen Studies on Asthma in Childhood
Obesity, Childhood, Asthma in Children
Asthma and Obesity Diet Versus Exercise
Obesity is recognized as a pro-inflammatory condition associated with multiple chronic diseases, including asthma. The specific mechanisms linking asthma and obesity remain hypothetical.
- Conditions
- Obesity, Childhood, Asthma in Children, Inflammatory Response, Metabolic Syndrome
- Trial name
- NCT03644355
- Testing
- Lifestyle counseling
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Asthma in Children
Alveolar and Serum sRAGE in Severe Asthma in Children
sRAGE is a recognized marker of alveolar injury in acute respiratory distress syndrome (ARDS). More recently, it seems to be an interesting marker in asthma.
- Trial name
- sRAGE (NCT05364996)
- Testing
- bronchial endoscopy with bronchoalveolar lavage (LBA), Blood sampling
- Where
- France
- Volunteers
- 85 people
- Sponsor
- University Hospital, Clermont-Ferrand
Asthma in Children
Factors Influencing Pediatric Asthma
Asthma is a chronic lung disease with serious morbidity and potential mortality. Multiple physiologic, environmental and social conditions impact the prevalence and severity of asthma.
- Trial name
- FIPA (NCT03302962)
- Testing
- Intensive Asthma Education
- Where
- United States
- Volunteers
- 324 people
- Sponsor
- Missouri Breaks Industries Research, Inc.