Clinical trials: Asthma Childhood
Pediatric Asthma
Humidity Asthma Interventions for Low Socioeconomic Status Children
The goal of this intervention study is to assess the effectiveness of low-cost humidity and mold reduction interventions in the home for reducing pediatric asthma.
- Trial name
- INHALE (NCT07453667)
- Testing
- Healthy home intervention
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Case Western Reserve University
Asthma in Children, Adherence, Treatment
Treatment Phenotypes for Adolescents With Asthma
This study will evaluate how adolescents take their asthma medications using an electronic medication monitor.
- Trial name
- NCT04228107
- Testing
- Medication monitoring
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Asthma, Asthma in Children
Effectiveness of a Mobile Health Intervention in Improving the Technique of Inhaled Medications Among Children With Asthma
In this trial, the investigators aim to determine if a new mobile health intervention (BreatheSuite) can increase inhaler technique and adherence amongst participants aged 10-18.
- Trial name
- NCT03615248
- Testing
- BreatheSuite
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Memorial University of Newfoundland
Asthma in Children
Early Identification of Children With Asthma
GPs are one of the key players in the early diagnosis of chronic diseases, such as asthma in pre-school children, by detecting symptoms of illness as early as possible.
- Trial name
- IDEA (NCT06988358)
- Testing
- Group of children identified by the algorithm as having asthma, Group of children not identified by the algorithm as having asthma
- Where
- 3 sites in France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Rouen
Asthma
Community Healthcare for Asthma Management and Prevention of Symptoms
The purpose of this study is to systematically investigate across health center study sites participating in this study the process of adopting, integrating, implementing, and diffusing a minimum set of evidence-based…
- Trial name
- CHAMPS (NCT02454192)
- Testing
- CHAMPS
- Where
- United States
- Volunteers
- 599 people
- Sponsor
- George Washington University
Asthma in Children
Effect of Mouth Breathing on Exercise Induced Bronchoconstriction.
Introduction: Exercise induced bronchoconstriction (EIB) is a common finding in the pediatric population with and without asthma.
- Trial name
- NCT05376436
- Testing
- Exercise challenge test (ECT)
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Childhood Asthma With Acute Exacerbation
Antibiotic Treatment of Recurrent Episodes of Asthma in Children
Copsac has discovered that asthmatic exacerbations are as closely linked to bacterial as to viral infection. The current study will examine whether treatment of asthmatic exacerbations with macrolide antibiotics - in the abscence…
- Trial name
- AB-studie (NCT01233297)
- Testing
- Azithromycin
- Where
- 2 sites in Denmark
- Volunteers
- 70 people
- Sponsor
- Copenhagen Studies on Asthma in Childhood
Asthma in Children
Stress and Treatment Response in Puerto Rican Children With Asthma
This study aims to first determine whether high child stress leads to reduced response to common treatmenIs for asthma (inhaled corticosteroids and short-acting bronchodilators), and then to identify DNA methylation differences…
- Trial name
- STAR (NCT03134755)
- Testing
- Inhaled corticosteroid (mometasone)
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 249 people
- Sponsor
- University of Pittsburgh
Asthma in Children
Promoting Asthma Management Guidelines With Technology-Based Intervention and Care Coordination in Clinics and Schools
The overall goal of this research study is to evaluate a multi-level program called PRAGMATIC-S to improve the delivery of guideline-based asthma care through a unique partnership between clinical practices and schools.
- Trial name
- PRAGMATIC-S (NCT07224061)
- Testing
- PRAGMATIC-S
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- Montefiore Medical Center
Asthma
Evaluation of a Shared Decision Making Portal for Pediatric Asthma
This pilot intervention study will test the feasibility and acceptability and explore the outcomes of a primary care-based shared decision making (SDM) electronic medical record (EMR)-based portal that provides education, elicits…
- Trial name
- NCT01715389
- Testing
- MyAsthma Patient Portal
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Children's Hospital of Philadelphia
Asthma (Diagnosis)
Pediatric Asthma Trial of Corticosteroid Heterogeneity (PATCH): Trial of Dexamethasone Versus Methylprednisolone for Pediatric Critical Asthma
Acute asthma exacerbation is caused by dysregulated pulmonary inflammatory pathways such that standard treatment includes prompt administration of exogenous systemic corticosteroids (SCs), but there remains an ongoing dialogue…
- Trial name
- PATCH (NCT07455396)
- Testing
- Dexamethasone (0.6mg/kg; Max 16mg) Once Daily, Dexamethasone (0.25 mg/kg/dose, Max dose 16mg) every 6-hours, Methylprednisolone
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Johns Hopkins All Children's Hospital
Pediatric Asthma
Developing a Childhood Asthma Risk Passive Digital Marker
Underdiagnosis and undertreatment is a major problem in childhood asthma management, especially in preschool-aged children. Current prognostic approaches using risk-score based tools have poor-to-modest accuracy, are impractical…
- Trial name
- NCT05826561
- Testing
- Childhood Asthma Passive Digital Marker
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Indiana University
Asthma in Children
Probiotics in Paediatric Asthma Management
Randomized controlled double-blind trial in a child population with allergic asthma and recurring wheezing, undergoing probiotic treatment with Bifiasthm with the aim of assessing the reduction in asthma attacks.
- Trial name
- ProPAM (NCT04289441)
- Testing
- Bifiasthm
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- Probiotical S.p.A.
Childhood Asthma
Experienced Chinese Herbal Formulas on Pediatric Asthma
The purpose of this study is conducting a randomized, single blind, controlled intervention trial to observe the therapeutic effect of experienced chinese herbal formulas based on different stages and different symptoms in…
- Trial name
- NCT02341573
- Testing
- experienced chinese herbal formulas, leukotriene receptor antagonist and bronchial relaxant
- Where
- China
- Volunteers
- 182 people
- Sponsor
- Children's Hospital of Fudan University
Childhood Asthma
lncRNA-based Nomogram to Assist Childhood Asthma Diagnosis
Asthma is the most common chronic disease in children, however, underdiagnosis of childhood asthma is an important issue in asthma management.
- Trial name
- NCT04525586
- Sponsor
- Children's Hospital of Fudan University
Asthma in Children
Personalised Outcomes in Children With Recurrent Wheeze
This project aims to develop a PROM for preschool children with recurrent wheeze. Nearly one third of children will have at least one episode of wheeze in the first five years of life.
- Trial name
- NCT03858010
- Testing
- Wheeze and me questionnaire
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Asthma in Children
Personalized Treatment Algorithms for Difficult-to-treat Asthma
Asthma is a common, complex and costly chronic condition. Moreover, asthma is heterogeneous in terms of treatment response. This heterogeneity contributes to the difficulty in both studying and treating asthma.
- Trial name
- NCT04179461
- Testing
- Cholecalciferol, antihistamine, Azithromycin
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Asthma in Children
Efficacy and Safety of Continuous Versus Intermittent Nebulization of Salbutamol in Acute Severe Asthma in Children Under 12 Years of Age
Asthma affects around 260 million people globally, causing around 0.5 million deaths annually. Pediatric asthma remains a major global public health challenge, significantly affecting the quality of life for many children.
- Trial name
- NCT06754631
- Testing
- Continuous Nebulization of Salbutamol, Intermittent Nebulization of Salbutamol
- Where
- 2 sites in Pakistan
- Volunteers
- 120 people
- Sponsor
- Muhammad Aamir Latif
Asthma, Asthma in Children
ED-Initiated School-based Asthma Medication Supervision
Asthma is a common chronic condition that causes substantial morbidity among children and much of it is attributable to medication non-adherence.
- Trial name
- EDSAMS (NCT03952286)
- Testing
- ED-Dispensing home and school supervision
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Arizona
Asthma in Children
Telemedicine Enhanced Asthma Management - Uniting Providers
This research study is an innovative school-based program for urban children with moderate to severe persistent or difficult-to-control asthma.
- Trial name
- TEAM-UP (NCT03545906)
- Testing
- TEAM-UP Intervention Group, Enhanced Care Comparison
- Where
- United States
- Volunteers
- 326 people
- Sponsor
- University of Rochester