Clinical trials: Asthma Childhood
Asthma
Montelukast Added to Standard Therapy for Acute Asthma in Children Age 6-14 Years
Oral montelukast is helpful in chronic asthma. The purpose of this pediatric study was to investigate whether the addition of oral montelukast to standard therapy for acute asthma exacerbations results in further improvement in…
- Trial name
- NCT00353184
- Testing
- Montelukast 5-mg orally added to standard therapy
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Washington University School of Medicine
Pediatric, Asthma, Acute Exacerbation, Pediatric ICU
Use of High Frequency Chest Compression in Pediatric Status Asthmaticus
Asthma is a disease resulting in mucus hypersecretion and airways obstruction. This causes difficulty breathing. The High Frequency Chest Compressor (HFCC) is a device that has been shown to decrease respiratory complications in…
- Trial name
- NCT00552448
- Testing
- High Frequency Chest Compression VEST
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Texas Tech University Health Sciences Center
Asthma in Children
Vitamin A and D Intake in Pregnancy, Infant Supplementation and Asthma Development
The objective of this study is to investigate if maternal intake of vitamins A and D from food and dietary supplements during pregnancy, and infant supplementation with these vitamins, are associated with development of asthma in…
- Trial name
- NCT03197233
- Testing
- Maternal vitamin A and D intake during pregnancy
- Volunteers
- 61,676 people
- Sponsor
- Norwegian Institute of Public Health
Asthma in Children, Wheezing
Secondhand Smoking in Asthmatic Children
This study will investigate the interaction between GSTP1 / TNFa polymorphisms and passive smoking in children with asthma/wheezing. Contemporary second hand-smoke exposure will be confirmed by laboratory testing.
- Trial name
- NCT03099902
- Testing
- Lung function, White blood cell DNA extraction, Urinary testing
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- AHEPA University Hospital
Asthma in Children, Children, Adult
Evaluation of the Possible Effect of Inspiratory Muscle Training on Inflammation Markers and Oxidative Stress in Childhood Asthma
As inflammation and oxidative stress increase in asthma patients, the severity of symptoms and clinical findings increase. Therefore, this study was planned to evaluate the possible effect of inspiratory muscle training (IMT) on…
- Trial name
- NCT05296707
- Testing
- Inspiratory muscle training, Used routine medicine, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Ege University
Bronchial Asthma, Childhood Asthma
Effect of Multimedia Protocol About Asthma Control
This study aims to evaluate the effect of multimedia protocol about asthma control on asthmatic children's adaptation in the era of climate changes.
- Conditions
- Bronchial Asthma, Childhood Asthma, Climate Change, Multimedia Learning Education
- Trial name
- NCT06974331
- Testing
- Multimedia Protocol about Asthma Control
- Where
- Egypt
- Volunteers
- 65 people
- Sponsor
- Mansoura University
Asthma in Children
A Study of Remote Asthma Management Using an Integrated Artificial Intelligence-assisted EHR Dashboard and Mobile Device Compared With Usual Asthma Care to Treat 6-17 Year Old Patients
The main purpose of this study is to look at whether clinicians and their patients with asthma can satisfactorily perform remote asthma management at home (not visiting clinic) by using an artificial intelligence tool called…
- Trial name
- NCT06062433
- Testing
- AsthmaTuner, Asthma-Guidance and Prediction System
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Asthma
Childhood Asthma Mentoring Program for Parents
There are 7.1 million children with asthma. Asthma is the cause of 10.5 million missed days of school, 7.5 million outpatient visits, 640,000 ED visits, and 157,000 hospitalization visits in 2008.
- Trial name
- CAMPP (NCT02747706)
- Testing
- Parent-to-parent mentoring
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- InquisitHealth, Inc.
Asthma in Children, Artificial Intelligence
AIR Support: Artificially Intelligent Robot (AIR) Support for Pediatric Asthma Education
The purpose of this prevention study is to evaluate the design and usability of a newly developed asthma education protocol with the Human Support Robot (HSR) for children with asthma.
- Trial name
- NCT07387718
- Testing
- Standard Asthma Education, Artificially Intelligent Robot (AIR) Support Intervention
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- University of Miami
Asthma in Children
Personalised Outcomes in Children With Recurrent Wheeze
This project aims to develop a PROM for preschool children with recurrent wheeze. Nearly one third of children will have at least one episode of wheeze in the first five years of life.
- Trial name
- NCT03858010
- Testing
- Wheeze and me questionnaire
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Asthma, Wheeze
Pediatric Arm of DZL All Age Asthma Cohort
Despite its common occurrence, still little is known about pathomechanisms determining different wheeze and asthma trajectories and phenotypes in children, and those beginning in adulthood.
- Conditions
- Asthma, Wheeze, Hypersensitivity, Endophenotype
- Trial name
- ALLIANCE (NCT02496468)
- Where
- 5 sites in Germany
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- LMU Klinikum
Asthma in Children
Use of a Modern Breath Sampling System (the Pneumopipe® Combined With an Array of E-nose Sensors) for the Prediction of Treatment Response in Persistent Asthmatic Children
Due to a large disease heterogeneity, the proper management of childhood asthma may be a challenging task. Despite the screening of lung function is a fundamental tool, spirometry alone may not allow a reliable prediction of the…
- Trial name
- Pneumo-Pred (NCT04326530)
- Testing
- Pneumopipe® (European patent 12425057.2, Rome, Italy), Other assessments
- Volunteers
- 150 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Asthma in Children, Implementation
Y of Central Maryland Head Start Asthma Implementation
Despite a strong evidence-base for the efficacy of multilevel programs in reducing asthma symptoms among low-income preschool minority children, gaps remain in our understanding of how to best translate and scale up these…
- Conditions
- Asthma in Children, Implementation, Preschool Children
- Trial name
- NCT05004714
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Johns Hopkins University
Asthma in Children, Allergy
Study of Indoor Air Pollutants and Their Impact in Childhood Health and Wellbeing
The number and types of indoor air pollutants in schools is rising, however little is known about the impact of their potentially synergistic interactions, upon schoolchildren health.
- Trial name
- SynAIR-G (NCT05997784)
- Testing
- Performing lung function tests (spirometry and fraction of exhaled nitric oxide (FeNO)), Filling of standardized questionnaires, Using an App on a device
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Asthma Exacerbation
Study of Preventive Treatment With Symbicort or Budicort Turbohaler in Childhood Asthma Return to School Epidemic
During the second week of September( week 38 of the year)there are recorded data of exacerbation of asthma all over the world, including Israel.
- Trial name
- NCT01179152
- Testing
- Budesonide turbuhaler, Budesonide+Formoterol turbuhaler
- Where
- Israel
- Volunteers
- 225 people
- Sponsor
- Meir Medical Center
Infant, Premature, Diseases, Infant
The Alberta BLOOM Long Term Follow Up Study
This is a prospective, observational clinical cohort study involving children born very preterm at less than 31 weeks and six days gestation.
- Conditions
- Infant, Premature, Diseases, Infant, Asthma, Asthma in Children
- Trial name
- BLOOM-LTFU (NCT04641000)
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Calgary
Asthma, Lung Diseases
Pediatric Asthma Controller Trial (PACT)
To evaluate current and novel therapies and management strategies for children with asthma. The emphasis is on clinical trials that help identify optimal therapy for children with different asthma phenotypes, genotypes, and…
- Trial name
- NCT00272506
- Testing
- inhaled corticosteroid, long-acting beta2-agonist
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Pediatric Asthma
High Flow Nasal Cannula Rates in Pediatric Asthma
This is a randomized, open-label, 3-armed feasibility trial will examine conventional oxygen therapy (COT) vs high flow nasal cannula at 4L/min flow vs HFNC at 2L/kg/min flow (max 60L/min) in moderate to severe pediatric asthma…
- Trial name
- NCT06379607
- Testing
- "High Flow" High Flow Nasal Cannula, "Low Flow" High Flow Nasal Cannula
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Rochester
Asthma in Children, Influenza Vaccine
Influenza Vaccine in Children With Asthma
The occurence of influenza can be a factor of imbalance of asthma. Asthma patients are recommended for annual influenza vaccination .
- Conditions
- Asthma in Children, Influenza Vaccine, Immunization Coverage
- Trial name
- VAGA (NCT04086628)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Central Hospital, Nancy, France
Asthma in Children, Obesity
Mechanistic Study of Inspiratory Training in Childhood Asthma (MICA)
This is single-center cross-sectional mechanistic study in lean and obese children with moderate-severe asthma, followed by a randomized, SHAM-controlled trial of Inspiratory Training (IT).
- Conditions
- Asthma in Children, Obesity, Pediatric Obesity, Pediatric Asthma
- Trial name
- MICA (NCT05945355)
- Testing
- Pro2 - Low Dose - 40% of participant's MIP, Pro2 - High Dose - 75% of participant's MIP
- Where
- 2 sites in United States
- Volunteers
- 76 people
- Sponsor
- Duke University