Clinical trials: Asthma Childhood
Asthma in Children
Integrating Deep Learning CT-scan Model, Biological and Clinical Variables to Predict Severity of Asthma in Children
Artificial intelligence (AI) offers substantial opportunities for healthcare, supporting better diagnosis, treatment, prevention and personalized care.
- Trial name
- BREATHE (NCT05140889)
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Asthma in Children
SMART Implementation-Effectiveness Trial 1
While single maintenance and reliever therapy (SMART) has been the preferred management strategy for Step 3 and 4 (moderate/severe) asthma management since the 2020 NIH asthma guideline updates, adoption of SMART has not been…
- Trial name
- SMART & SIMPLE (NCT07137923)
- Testing
- Clinical decision support + education (CDS+), Control
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Children's Hospital of Philadelphia
Asthma
Comparison of Nebulizers in ED in Pediatric Asthma Patients
The primary objective will be, in an open-label randomized trial, a comparison of emergency department (ED) length of stay (LOS) between children experiencing acute asthma treated with two different nebulizers.
- Trial name
- NCT01951378
- Testing
- Hudson RCI® nebulizer, NebuTech® HDN® nebulizer, Albuterol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Seton Healthcare Family
Asthma, Wheeze
Pediatric Arm of DZL All Age Asthma Cohort
Despite its common occurrence, still little is known about pathomechanisms determining different wheeze and asthma trajectories and phenotypes in children, and those beginning in adulthood.
- Conditions
- Asthma, Wheeze, Hypersensitivity, Endophenotype
- Trial name
- ALLIANCE (NCT02496468)
- Where
- 5 sites in Germany
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- LMU Klinikum
Asthma in Children, Allergy
Study of Indoor Air Pollutants and Their Impact in Childhood Health and Wellbeing
The number and types of indoor air pollutants in schools is rising, however little is known about the impact of their potentially synergistic interactions, upon schoolchildren health.
- Trial name
- SynAIR-G (NCT05997784)
- Testing
- Performing lung function tests (spirometry and fraction of exhaled nitric oxide (FeNO)), Filling of standardized questionnaires, Using an App on a device
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Allergy and Asthma
Allergy and Ashthma in Children Who Were Fed Supplemented Infant Formula
Allergy and Asthma study of children (3 - 7 Years of age) who participated in randomized trials of supplemented infant formula during infancy conducted by The Retina Foundation of the Southwest .
- Trial name
- NCT01205659
- Where
- United States
- Sponsor
- Mead Johnson Nutrition
Childhood Asthma
More Relaxation by Deep Breath on Methacholine
Deep inhalation (DI) dilates normal airway precontracted with methacholine. The fact that this effect is diminished or absent in asthma could be explained by the presence of bronchial inflammation.
- Trial name
- SouProvocBro (NCT03696602)
- Testing
- bronchial provocation test
- Volunteers
- 78 people
- Sponsor
- Central Hospital, Nancy, France
Asthma, Lung Diseases
Childhood Asthma Research and Education (CARE) Network Trial - Acute Intervention Management Strategies (AIMS)
This study will determine the effectiveness of initiating a high-dose inhaled corticosteroid (ICS) or a leukotriene receptor antagonist (LTRA) in addition to an inhaled beta2-agonist (albuterol) at the onset of respiratory tract…
- Trial name
- AIMS (NCT00319488)
- Testing
- Inhaled Corticosteroid (Budesonide), Leukotriene Receptor Antagonist (Montelukast Sodium), Inhaled Albuterol
- Where
- 6 sites in United States
- Volunteers
- 238 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Asthma in Children, Asthma Attack
Timely Administration of IV Magnesium Sulfate in Patients With a Moderate Asthma Exacerbation
This study aims to identify whether early administration of magnesium sulfate in moderate asthma exacerbations can potentially avoid admission, decrease length of stay in the emergency department (ED), decrease length of stay…
- Trial name
- NCT06137040
- Testing
- Magnesium Sulfate within the first hour, No Magnesium sulfate within the first hour
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Oklahoma
Pediatric, Asthma, Acute Exacerbation, Pediatric ICU
Use of High Frequency Chest Compression in Pediatric Status Asthmaticus
Asthma is a disease resulting in mucus hypersecretion and airways obstruction. This causes difficulty breathing. The High Frequency Chest Compressor (HFCC) is a device that has been shown to decrease respiratory complications in…
- Trial name
- NCT00552448
- Testing
- High Frequency Chest Compression VEST
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Texas Tech University Health Sciences Center
Asthma Exacerbation
Study of Preventive Treatment With Symbicort or Budicort Turbohaler in Childhood Asthma Return to School Epidemic
During the second week of September( week 38 of the year)there are recorded data of exacerbation of asthma all over the world, including Israel.
- Trial name
- NCT01179152
- Testing
- Budesonide turbuhaler, Budesonide+Formoterol turbuhaler
- Where
- Israel
- Volunteers
- 225 people
- Sponsor
- Meir Medical Center
Pediatric Asthma
Implementing a Guidelines-Based M-Health Intervention for High Risk Asthma Patients
The goal of this research study is to test how good an app is in making asthma easier to manage for 372 adolescents/young adults. The app is a mobile version of the asthma action plan.
- Trial name
- PEAKmAAP (NCT03842033)
- Testing
- PEAKmAAP, PEAKmAAP-DS, NutriMap Usual Care
- Where
- United States
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Asthma
Timely Intravenous Magnesium for Asthma in Children
Many children currently being hospitalized with severe asthma could potentially avoid hospitalization and be sent home if their treatment in the emergency department was more effective.
- Trial name
- IMPACT-ED (NCT05166811)
- Testing
- Magnesium Sulfate, Heptahydrate, 0.9% saline
- Where
- 3 sites in United States
- Volunteers
- 52 people
- Sponsor
- University of Utah
Pediatric Asthma
School-Based Telemedicine Enhanced Asthma Management
This project aims to improve guideline-based asthma care using enhanced communication and screening tools, telemedicine and directly observed therapy of preventive medications in city schools.
- Trial name
- SB-TEAM (NCT01650844)
- Testing
- School-Based Telemedicine Enhanced Asthma Management, Enhanced Usual Care
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Rochester
Asthma in Children, Adherence, Treatment
Treatment Phenotypes for Adolescents With Asthma
This study will evaluate how adolescents take their asthma medications using an electronic medication monitor.
- Trial name
- NCT04228107
- Testing
- Medication monitoring
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Asthma
Community Healthcare for Asthma Management and Prevention of Symptoms
The purpose of this study is to systematically investigate across health center study sites participating in this study the process of adopting, integrating, implementing, and diffusing a minimum set of evidence-based…
- Trial name
- CHAMPS (NCT02454192)
- Testing
- CHAMPS
- Where
- United States
- Volunteers
- 599 people
- Sponsor
- George Washington University
Asthma Childhood, Respiratory Muscle Training
Effects of Expiratory Muscle Training in Children With Asthma: A Randomised Controlled Trial
The goal of this randomized clinical trial is to evaluate the effectiveness of expiratory muscle training (EMT) as an adjunct to conventional chest physiotherapy in children with asthma.
- Trial name
- NCT07169071
- Testing
- Home-based chest physiotherapy program, Expiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Atlas University
Asthma, Pediatric Asthma
Asthma Lung Sounds With Wearable Stethoscope
The goal of this clinical trial is to evaluate a prototype wearable stethoscope designed to record lung sounds and assess asthma control in children and adolescents with asthma aged 4 to 17 years who are able to perform…
- Conditions
- Asthma, Pediatric Asthma, Airway Obstruction Upper
- Trial name
- NCT07792330
- Testing
- Prototype Wearable Stethoscope
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Children's Hospital Los Angeles
Smoking Reduction, Asthma in Children
Early Life Intervention in Pediatrics Supported by E-health - SMOKE
Unrestricted parental smoking habits are lifestyle risk behaviors associated with chronic, systemic inflammation, which promotes the pathogenesis of non-communicable diseases (NCDs).
- Conditions
- Smoking Reduction, Asthma in Children, Wheezing, Non-Communicable Disease
- Trial name
- ELIPSE-II (NCT06311162)
- Testing
- Life-Style app
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Asthma in Children
Magnesium Sulfate in Bronchial Asthma and Acute Bronchiolitis in Children
Asthma is a prevalent disease that affects as many as334 million individuals worldwide, and is a major source of disability and premature death in children(1). Asthma affects 7.1 million children in the United States (2).
- Trial name
- NCT06955559
- Testing
- Magnesium sulfate
- Volunteers
- 60 people
- Sponsor
- Assiut University