Clinical trials: Asthma Control
Respiratory Syncytial Virus (RSV)
A Study to Investigate the Safety and Tolerability of Single and Repeat Doses of PC786
This study investigates the safety, tolerability and pharmacokinetics of single and repeat doses of PC786.
- Trial name
- NCT03236233
- Testing
- PC786 - Single doses, PC786 - Repeat doses
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Pulmocide Ltd
Healthy
Normal Control Cohort Sample Bank
This study is designed to collect lung washing samples and small pieces of tissue (biopsies) from the lungs of people who do not have any allergies or asthma.
- Trial name
- NCT00388765
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Asthma in Children
Accuracy of the Association Between the "PA-R" and "ACT" Questionnaires in Asthmatic Pediatric Patients
A patient with asthma requires daily and long-term pharmacological treatment when symptoms are frequent and/or severe. International guidelines suggest increasing or reducing pharmacological therapy based on the individual's…
- Trial name
- QAS (NCT06844266)
- Testing
- Administration of the ACT + PA-R questionnaires, ACT questionnaire
- Volunteers
- 174 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Asthma
Randomised Study Comparing the Effects of Inhaled FF/GW642444M Combination, FF and GW642444M on an Allergen Induced Asthmatic Response
We propose to use an inhaled allergen challenge model to explore the individual contributions of the components of a novel long-acting beta agonist/ inhaled corticosteroid combination product and its components on protection from…
- Trial name
- NCT01128595
- Testing
- FF/GW642444M, GW642444M, Fluticasone Furoate
- Where
- 4 sites in Australia, New Zealand and 1 more
- Volunteers
- 27 people
- Sponsor
- GlaxoSmithKline
Asthma
Crossover Study to Evaluate the Efficacy, Safety and Tolerability of Different Doses of Indacaterol in Patients With Persistent Asthma
The purpose of this study is to determine the efficacy of indacaterol 55µg once daily (and 27.5 µg twice) in QVA149 compared to 75 µg indacaterol monotherapy.
- Trial name
- QAB149 (NCT01959412)
- Testing
- Indacaterol 27.5 mcg, Indacaterol 37.5, Indacaterol 55 mcg
- Where
- 12 sites in United States
- Volunteers
- 91 people
- Sponsor
- Novartis Pharmaceuticals
Asthma
Safety, Tolerability, and Pharcodynamics of AMG 853 in Adolescents With Asthma
The purpose of this study is to study the safety and tolerability in adolescent and adult subjects with intermittent or mild to moderate persistent asthma.
- Trial name
- NCT01137565
- Testing
- AMG 853
- Volunteers
- 23 people
- Sponsor
- Amgen
Asthma
Valuation of Quality of Life in Children With Asthma
The aim of the study is valuation of quality of life (QL) in children with asthma and analysis of the factors that can have influence on it.
- Trial name
- NCT00491101
- Testing
- Polish Version of PAQLQ(S) by Juniper, spirometry
- Where
- Poland
- Volunteers
- 110 people
- Sponsor
- Medical University of Lodz
Allergic Rhinitis Due to Dermatophagoides Farinae, Allergic Rhinitis Due to Dermatophagoides Pteronyssinus
House Dust Mite Allergy Trial In Children
A research study of how house dust mite tablets work compared to placebo in children aged between 5 and 11 years and who have allergy to house dust mites (MATIC)
- Conditions
- Allergic Rhinitis Due to Dermatophagoides Farinae, Allergic Rhinitis Due to Dermatophagoides Pteronyssinus, Allergic Rhinitis Due to House Dust Mite
- Trial name
- MATIC (NCT04145219)
- Testing
- Sublingual allergy immunotherapy tablet
- Where
- 113 sites in United States, Bulgaria and 9 more
- Volunteers
- 1,460 people
- Sponsor
- ALK-Abelló A/S
Asthma, Obesity
Effectiveness and Efficiency of Mobile Technology in Disease Control of Asthmatic Obese Patients
Single-center open-label randomized pilot study to assess the effectiveness and efficiency of a mobile technology based intervention for asthma and obesity control.
- Trial name
- ASMATIC (NCT03964740)
- Testing
- Mobile App intervention
- Where
- Spain
- Volunteers
- 33 people
- Sponsor
- Hospital Universitario Virgen Macarena
Asthma
Study Evaluating the Effects of AIR645 on Allergen-Induced Airway Responses in Subjects With Mild Atopic Asthma
To assess the efficacy of inhaled AIR645 in the suppression of the Asthmatic Responses in subjects with mild asthma inhaling an allergen.
- Trial name
- NCT00941577
- Testing
- AIR645, Physiologic saline solution
- Where
- 3 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Altair Therapeutics, Inc.
Asthma
This Study Compared an in Home Asthma Management Program Provided by Nurses or Respiratory Therapist
This study compared an in-home asthma management program provided by nurses or respiratory therapists to see if those receiving program had fewer hospitalizations, clinic and emergency room visits and higher levels of…
- Trial name
- NCT00639847
- Testing
- In-home asthma management program (AMP) provided by nurses, In-home asthma management program (AMP) provided by respiratory therapists
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Atopic Dermatitis, Psoriasis
Study in Healthy Participants and Participants With Moderate Atopic Dermatitis & Optionally, Moderate Psoriasis, and/or Mild Asthma
This Phase 1 study will investigate the safety and tolerability of EDP1867 in healthy volunteers, participants with atopic dermatitis, and, optionally, in participants with psoriasis and/or asthma.
- Conditions
- Atopic Dermatitis, Psoriasis, Asthma
- Trial name
- NCT04927195
- Testing
- EDP1867
- Where
- 7 sites in United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Evelo Biosciences, Inc.
Obstructive Pulmonary Disease, Mechanical Ventilation Pressure High
FCV vs VCV in Obstructive and Asthmatic Patients
The goal of this physiological pilot study with a randomized crossover design is to study the effect of Flow-controlled ventilation (FCV) on the minute volume compared to Volume-controlled ventilation (VCV) in intubated patients…
- Conditions
- Obstructive Pulmonary Disease, Mechanical Ventilation Pressure High, Asthma COPD
- Trial name
- NCT06563544
- Testing
- FCV
- Where
- 2 sites in Netherlands
- Volunteers
- 10 people
- Sponsor
- Erasmus Medical Center
Asthma
Efficacy and Safety Study to Compare Formoterol Fumerate in the Pressair DPI to the Foradil Aerolizer in Patient With Mild to Moderate Asthma
The purpose of this Phase II study is to evaluate efficacy and safety of inhaled formoterol fumarate in the Pressair DPI compared to the Foradil Aerolizer in patients with mild to moderate asthma.
- Trial name
- NCT01641081
- Testing
- Formoterol Fumarate in the Pressair DPI, Low Dose, Formoterol Fumarate in the Pressair DPI, High Dose, Foradil Aerolizer, Low Dose
- Where
- 29 sites in United States
- Volunteers
- 174 people
- Sponsor
- AstraZeneca
Asthma, COPD
Acoustic Waveform Respiratory Evaluation
The study will evaluate the feasibility of using smartphone speakers and microphones to evaluate the caliber of the airways, detect airway obstruction, aid in airway disease diagnosis, and identify disease exacerbations.
- Conditions
- Asthma, COPD, Cystic Fibrosis, Ciliary Motility Disorders
- Trial name
- AWARE (NCT06512064)
- Testing
- AWARE
- Where
- 2 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Indiana University
Asthma
Dose Ranging Study of Amlitelimab in Adult Participants With Moderate-to-severe Asthma
This was a parallel, Phase 2, global, multicenter, randomized, double-blind, placebo-controlled, dose-ranging, four-arms study for treatment.
- Trial name
- TIDE-asthma (NCT05421598)
- Testing
- Amlitelimab
- Where
- 113 sites in United States, Argentina and 12 more
- Volunteers
- 437 people
- Sponsor
- Sanofi
Asthma
European Cost of Asthma Treatment
The economic cost of asthma is considerable both in terms of direct medical costs (such as the cost of pharmaceuticals and hospital admissions) and indirect medical costs (such as time lost from work and premature death).
- Trial name
- EU-COAST (NCT01376219)
- Testing
- asthma control test
- Where
- Spain
- Volunteers
- 2,752 people
- Sponsor
- GlaxoSmithKline
Asthma
Physical Activity Intervention for Black Women With Asthma
Physical inactivity is associated with poor asthma control and quality of life, and greater health care utilization. Rates of physical inactivity, asthma, and asthma mortality among Black women are higher than those of their…
- Trial name
- ACTION E2I (NCT05726487)
- Testing
- ACTION Intervention, Education Control
- Where
- 2 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Asthma
New Version Pulmicort Turbuhaler USA Adults
A comparison of the safety, efficacy and budesonide pharmacokinetics of the currently approved Pulmicort Turbuhaler with a new version of the inhaler, in adult patients who have asthma and are currently being treated with inhaled…
- Trial name
- NCT00642187
- Testing
- budesonide
- Volunteers
- 525 people
- Sponsor
- AstraZeneca
Asthma
A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma
The aim of this study is to evaluate the efficacy of depemokimab administered as an adjunctive therapy, in participants with Type 2 asthma at risk of exacerbations compared to the guideline recommended standard of care (SoC).
- Trial name
- MODIFY (NCT07456033)
- Testing
- Depemokimab
- Where
- 17 sites in United States, United Kingdom
- Volunteers
- 456 people
- Sponsor
- GlaxoSmithKline