Clinical trials: Asthma Copd
Diabetes, Heart Failure
Avoidable Hospitalizations/ Emergency Department Visits- Systematic Review and Meta-synthesis of Qualitative Research
The aim of the study is to synthesize qualitative evidence related to preventable hospitalizations/ emergency department visits from the perspectives of patients, their families/caregivers, health care providers, and…
- Conditions
- Diabetes, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT05456906
- Testing
- No intervention
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Kaohsiung Medical University
Chronic Obstructive Pulmonary Disease (COPD), Asthma
Two-part Pharmacokinetic and Pharmacodynamic Study of LAS190792 in Patients With Asthma and COPD
The purpose of this study is to assess the safety and tolerability of single doses of LAS190792 administered by inhalation to patients with mild persistent asthma and moderate to severe chronic obstructive pulmonary disease…
- Trial name
- NCT02059434
- Testing
- LAS190792 Dose 1, LAS190792 Dose 2, LAS190792 Dose 3
- Where
- 2 sites in United Kingdom
- Volunteers
- 55 people
- Sponsor
- AstraZeneca
Asthma, Copd
A Study to Obtain Normal Values of Inflammatory Variables From Healthy Subjects
Smoking induces an inflammatory reaction in the airways which can ultimately result in persistent damage and the development of a Chronic Obstructive Pulmonary Disease (COPD). However, not all subjects who smoke end up with COPD.
- Trial name
- NORM (NCT00848406)
- Where
- Netherlands
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Chronic Obstructive Pulmonary Disease, Asthma
Evaluation of ST2 and IL-33 in Patients Presenting to the Emergency Department With Trouble Breathing
Trouble breathing (dyspnea) is a nonspecific symptom associated with many diseases such as chronic obstructive pulmonary disease (lung disorder in which the flow of air to the lungs is blocked), asthma, pneumonia, pulmonary…
- Conditions
- Chronic Obstructive Pulmonary Disease, Asthma, Pulmonary Embolism, Pneumonia
- Trial name
- NCT00707811
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- The Cleveland Clinic
Pulmonary Disease, Chronic Obstructive
Genomic/ Proteomic/ Metabonomic Profiling in Chronic Obstructive Pulmonary Disease (COPD)
Chronic obstructive pulmonary disease (COPD) is a chronic disease characterized by progressive airflow obstruction, chronic cough and dyspnoea in advanced stages. We hope to develop a better understanding of lung disease.
- Trial name
- NCT00655694
- Testing
- sputum, blood, urine, exhaled breath, lung function
- Where
- United Kingdom
- Sponsor
- Imperial College London
Asthma, Respiratory Candidiasis
The Effect of PC945 on Aspergillus or Candida Lung Infections in Patients With Asthma or Chronic Respiratory Diseases
This study tests the effects of an experimental drug PC945 in people with asthma or other chronic respiratory diseases whose lungs are infected by Aspergillus fungi and Candida yeasts.
- Conditions
- Asthma, Respiratory Candidiasis, Respiratory Aspergillosis, COPD
- Trial name
- NCT03745196
- Testing
- PC945
- Where
- 4 sites in United Kingdom
- Volunteers
- 13 people
- Sponsor
- Pulmocide Ltd
Chronic Obstructive Pulmonary Disease, Asthma
Vibration Response Imaging in Chronic Obstructive Pulmonary Disease and Asthma
Obstructive lung disease is usually a differential diagnostic consideration when a patient presents with breathlessness or cough.
- Trial name
- NCT00542282
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Deep Breeze
Pulmonary Disease, Asthma
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cells for Pulmonary Diseases
This trial will study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells for the treatment of Pulmonary Diseases
- Conditions
- Pulmonary Disease, Asthma, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT05147688
- Testing
- cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells
- Where
- 2 sites in United States, Greece
- Volunteers
- 20 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Chronic Non-communicable Disease
Risk Factors at Chronic Non-communicable Diseases in People of Working Age
Objectives: to study the clinical and demographic characteristics of working age persons, to highlight the main factors of non-communicable diseases (NCDs), to identify NCDs with physical examination, laboratory tests…
- Trial name
- FORTUNE (NCT06812767)
- Testing
- electrocardiography, analysis for glucose and cholesterol in the capillary blood, detection of microalbumuria
- Where
- Russia
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Asthma
Bronchodilator Properties and Safety in Asthma
Recent large clinical studies have demonstrated the interest of LAMA therapy in the management of asthma, when compared to LABA.
- Trial name
- NCT01951222
- Testing
- V0162
- Where
- Germany
- Volunteers
- 59 people
- Sponsor
- Pierre Fabre Medicament
Chronic Bronchitis, Asthma
Dietary and Genetic Factors in Asthma & Chronic Bronchitis in a Cohort of Chinese Singaporeans
There is suggestive evidence for a role of dietary in the etiology of asthma and chronic bronchitis. However, there are few prospective data.
- Trial name
- NCT00342030
- Where
- Singapore
- Volunteers
- 63,257 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Asthma, Chronic Obstructive Pulmonary Disease
Evaluation of the Efficacy of Respicure® (Resveratrol / Quercetin) in the Management of Respiratory Conditions Including Asthma,COPD and Long COVID.
Interventional, Prospective, National, Multicentre, Randomised, Open-label, Controlled Clinical Study Comparing Two Parallel Groups, One Control Arm (Standard Treatment) Versus Intervention Arm (Standard Treatment + Study…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease, Long COVID
- Trial name
- NCT05601180
- Testing
- Respicure®, Standard of care
- Where
- 8 sites in Algeria
- Volunteers
- 402 people
- Sponsor
- Beker Laboratories
Asthma, Chronic Obstructive Pulmonary Disease
Reliability of a Top Mount Actuation Indicator With Levalbuterol MDI in Adult and Pediatric Subjects With Asthma or COPD
This is a study to investigate the reliability, ruggedness and safety of the top mounted actuation indicator (TMAI) when used with Levalbuterol HFA MDI.
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease, COPD
- Trial name
- NCT00583986
- Testing
- Levalbuterol HFA MDI with top mounted actuation indicator
- Where
- 26 sites in United States
- Volunteers
- 150 people
- Sponsor
- Sumitomo Pharma America, Inc.
Lung Cancer, Emphysema
CryoSpray Ablation(tm)Thoracic Patient Registry
The purpose of this study is to create a patient registry to collect and analyze information on subjects treated with the CryoSpray Ablation™ System post-510K approval.
- Conditions
- Lung Cancer, Emphysema, Chronic Bronchitis, COPD
- Trial name
- NCT00785239
- Sponsor
- CSA Medical, Inc.
Asthma, COPD
Teaching Use of Respiratory Inhalers (TURI)
The purpose of this study is to evaluate the feasibility of enrolling and randomizing patients into one of two educational interventions to teach appropriate respiratory inhaler technique and to collect preliminary estimates of…
- Trial name
- TURI (NCT01456494)
- Testing
- Brief Intervention, Teach-to-Goal Education
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Chicago
COPD (Chronic Obstructive Pulmonary Disease), Cystic Fibrosis (CF)
ELECTROVEST: Electro-Stimulation Vibratory Vest for Pulmonary Rehabilitation in Patients With Chronic Respiratory Diseases
This study will evaluate the effectiveness, safety, and tolerability of a novel wearable device, the ELECTROVEST, designed to improve airway clearance in patients with chronic respiratory diseases.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), Cystic Fibrosis (CF), Bronchiectasis Adult, Asthma Bronchiale
- Trial name
- Electrovest (NCT07175012)
- Testing
- ELECTROVEST, The Vest® Model 105
- Where
- Spain
- Volunteers
- 21 people
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Asthma, Chronic Obstructive Pulmonary Disease
Inspiratory Flow Parameters of Easyhaler and Diskus Inhalers (SALIF)
The purpose of this study is to characterise inspiratory flow parameters across 2 Easyhaler® (EH) inhaler versions and Diskus® inhaler in patients with asthma (including children, adults, and the elderly) and in patients with…
- Trial name
- SALIF (NCT01424137)
- Testing
- Easyhaler type A, Easyhaler type B, Diskus inhaler
- Where
- 5 sites in Estonia, Finland
- Volunteers
- 227 people
- Sponsor
- Orion Corporation, Orion Pharma
Asthma, COPD
Blood Collection From Individuals With Lung Disease for Genetic Studies
This is a research study where researchers are collecting blood to evaluate the genetic characteristics of individuals with chronic lung diseases, including asthma, chronic obstructive pulmonary disease (COPD), interstitial lung…
- Conditions
- Asthma, COPD, Interstitial Lung Disease, Cystic Fibrosis
- Trial name
- NCT00362739
- Where
- United States
- Volunteers
- 3,087 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Asthma
Study to Assess the Efficacy of a Single PBF-680 Oral Administration to Attenuate Adenosine 5'-Monophosphate Challenge-induced Airway Hyperresponsiveness in Mild-to-moderate Asthmatics
This is a single-center, double-blind, randomized trial utilizing a three-period, balanced block design, with each period comprising a unique study product administration.
- Trial name
- NCT01939587
- Testing
- PBF-680 5 mg, PBF-680 20 mg
- Where
- 2 sites in Spain
- Volunteers
- 21 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
COPD, Emphysema, Asthma COPD Overlap, Emphysema
Site and Mechanism(s) of Expiratory Airflow Limitation in COPD, Emphysema and Asthma-COPD Overlap
The purpose of this cross-sectional, observational study is to evaluate the site and mechanism(s) for expiratory airflow limitation in chronic, treated, current or former smokers (>15 pack years) with COPD, Emphysema, and…
- Trial name
- NCT03263130
- Testing
- As above: diagnosis: COPD, Emphysema, Asthma-COPD Overlap
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gelb, Arthur F., M.D.