Clinical trials: Asthma Management
Asthma
Study of Mepolizumab Autoinjector in Asthmatics
This study is aimed to assess the correct real-world use of an autoinjector for the repeat self-administration of mepolizumab SC, so to improve subject / physician convenience and to enable repeat dose self injection themselves…
- Trial name
- NCT03099096
- Testing
- Mepolizumab
- Where
- 38 sites in United States, Australia and 5 more
- Volunteers
- 159 people
- Sponsor
- GlaxoSmithKline
Asthma, Healthy
A Study to Assess Bioavailability and Pharmacokinetics of CAT- 354
To compare bioavailability and pharmacokinetics of CAT-354 following subcutaneous administration compared with intravenous administration.
- Trial name
- NCT00638989
- Testing
- CAT-354 150 mg (intravenous), CAT-354 150 mg (subcutaneous), CAT-354 300 mg (subcutaneous)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Effectiveness of Interventions to Teach Respiratory Inhaler Technique (E-TRaIN)
The purpose of this study is to evaluate the relative effectiveness of two different ways to teach subjects while hospitalized how to use respiratory inhalers and to follow-up after discharge home from the hospital to determine…
- Trial name
- E-TRaIN (NCT01426581)
- Testing
- Teach-To-Goal, Brief Intervention
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Chicago
Asthma
Telecommunication Enhanced Asthma Management
The primary aim of this project is to conduct a randomized practical clinical trial within a large health maintenance organization to test a telephone intervention designed to improve adherence to daily asthma medications and…
- Trial name
- TEAM (NCT00958932)
- Testing
- Speech recognition
- Where
- United States
- Volunteers
- 1,187 people
- Sponsor
- National Jewish Health
Childhood Asthma, Community Health Workers
West Philadelphia Controls Asthma
This project uses community health workers (CHW) or lay health educators to implement asthma interventions that have been proven to work in the primary care setting and in schools.
- Trial name
- WPCA (NCT03514485)
- Testing
- Yes We Can Children's Asthma Program, School-Based Asthma Therapy, Open Airways for School Plus
- Where
- United States
- Volunteers
- 626 people
- Sponsor
- Children's Hospital of Philadelphia
Asthma, Asthma in Children
ED-Initiated School-based Asthma Medication Supervision
Asthma is a common chronic condition that causes substantial morbidity among children and much of it is attributable to medication non-adherence.
- Trial name
- EDSAMS (NCT03952286)
- Testing
- ED-Dispensing home and school supervision
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Arizona
Asthma in Children
Early Administration of Steroids in the Ambulance Setting
Asthma is the most common chronic disease of childhood and is a leading cause of emergency medical treatment. For children experiencing an asthma exacerbation, emergency department (ED) guidelines recommend early systemic…
- Trial name
- EASI-AS-ODT (NCT03962894)
- Testing
- Prednisolone
- Where
- 7 sites in United States
- Volunteers
- 834 people
- Sponsor
- University of Florida
Asthma
Peer Led Asthma Self Management for Adolescents: PLASMA
Asthma is a serious chronic health condition particularly in inner-city adolescents, who suffer disproportionately high asthma-related morbidity and mortality that place heavy economic burdens on families and society.
- Trial name
- PLASMA (NCT02293499)
- Testing
- PLASMA
- Where
- 4 sites in United States
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Persistent Allergic Asthma
Evaluate the Effect of Omalizumab on Markers of Asthma Impairment in Patients With Persistent Allergic Asthma
This study will evaluate the effect of omalizumab on markers of impairment in patients with inadequately controlled persistent allergic asthma on Step 4 or above therapy as defined in the 2007 National Heart, Lung, and Blood…
- Trial name
- NCT00870584
- Testing
- Omalizumab
- Where
- 50 sites in United States
- Volunteers
- 271 people
- Sponsor
- Novartis Pharmaceuticals
Uncontrolled Asthma, Young Adults
Medication Adherence With Telehealthcare Medication Therapy Management
Improving Medication Adherence with Telehealthcare Medication Therapy Management to Change Health Outcomes in Adolescents and Young Adults with Asthma (MATCH) is a multi-center, randomized parallel group study targeted to an…
- Trial name
- MATCH (NCT03978936)
- Testing
- Medication Therapy Management (MTM) Video Telehealthcare, Electronic Adherence Self-Management (EAM)
- Where
- 21 sites in United States
- Volunteers
- 375 people
- Sponsor
- Johns Hopkins University
Asthma
Symptom Perception
Older asthmatics have considerably worse outcomes than younger patients with asthma. In this study, the investigators will evaluate the role of symptom perception as a key determinant of poorer outcomes and lower adherence to…
- Trial name
- NCT03646669
- Testing
- PEF Feedback, Asthma education
- Where
- 3 sites in United States
- Volunteers
- 58 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pediatric Asthma
School-Based Telemedicine Enhanced Asthma Management
This project aims to improve guideline-based asthma care using enhanced communication and screening tools, telemedicine and directly observed therapy of preventive medications in city schools.
- Trial name
- SB-TEAM (NCT01650844)
- Testing
- School-Based Telemedicine Enhanced Asthma Management, Enhanced Usual Care
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Rochester
Asthma
Administration of ARS-1 or Albuterol in Subjects With Persistent Asthma
ARS-1 is being developed for patients as a needleless alternative route of epinephrine administration for the management of refractory asthma symptoms.
- Trial name
- NCT05363670
- Testing
- ARS-1 1 mg, Albuterol MDI, ARS-1 2mg
- Where
- 4 sites in United States
- Volunteers
- 18 people
- Sponsor
- ARS Pharmaceuticals, Inc.
Asthma
Safety, Tolerability, and Efficacy of AIN457 in Patients With Uncontrolled Asthma
This study is a preliminary proof of efficacy study of AIN457 in patients with bronchial asthma that is poorly controlled with the current standard of care.
- Trial name
- NCT01478360
- Testing
- AIN457 (secukinumab)
- Where
- 9 sites in Germany, United Kingdom
- Volunteers
- 46 people
- Sponsor
- Novartis Pharmaceuticals
Asthma in Children
Telemedicine Enhanced Asthma Management - Uniting Providers
This research study is an innovative school-based program for urban children with moderate to severe persistent or difficult-to-control asthma.
- Trial name
- TEAM-UP (NCT03545906)
- Testing
- TEAM-UP Intervention Group, Enhanced Care Comparison
- Where
- United States
- Volunteers
- 326 people
- Sponsor
- University of Rochester
Asthma
Study of Efficacy and Safety of QAW039 When Added to Standard-of-care Asthma Therapy in Patients With Uncontrolled Asthma
A randomized, multicenter, double-blind, placebo- controlled parallel-group study to determine the efficacy and safety of QAW039, compared with placebo, when added to standard-of-care (SoC) asthma therapy in adult and adolescent…
- Trial name
- NCT03215758
- Testing
- QAW039
- Where
- 110 sites in United States, Argentina and 8 more
- Volunteers
- 675 people
- Sponsor
- Novartis Pharmaceuticals
Asthma
Study of Mepolizumab Safety Syringe in Asthmatics
This study is aimed to assess the correct real-world use of a safety syringe for the repeat self-administration of mepolizumab SC.
- Trial name
- NCT03021304
- Testing
- Mepolizumab
- Where
- 15 sites in United States, Canada and 3 more
- Volunteers
- 56 people
- Sponsor
- GlaxoSmithKline
Asthma
School-based Asthma Care for Teens (SB-ACT)
The goal of this study is to evaluate the widespread implementation of a developmentally appropriate preventive asthma care intervention for urban teens.
- Trial name
- SB-ACT (NCT02206061)
- Testing
- School-Based Asthma Care for Teens (SB-ACT), Directly Observed Therapy, Asthma Education
- Where
- United States
- Volunteers
- 430 people
- Sponsor
- University of Rochester