Clinical trials: Asthma Patients
Rhinoconjunctivitis, Allergic Asthma
2nd Pivotal Study rPhleum - Adults and Adolescents With Rhinoconjunctivitis +/-Controlled Asthma
To evaluate efficacy and tolerability of specific subcutaneous immunotherapy with a cocktail of recombinant major allergens of Timothy Grass Pollen (Phleum pratense) in subjects with rhinoconjunctivitis caused by grass pollen…
- Trial name
- NCT01353755
- Testing
- Grass pollen specific immunotherapy, Placabo
- Where
- Germany
- Volunteers
- 195 people
- Sponsor
- Allergopharma GmbH & Co. KG
Asthma
A Study to Evaluate the Safety and Tolerability of Multiple Dose of IBI3002 in Healthy and Asthmatic Participants
This study is a randomized, double-blind, placebo-controlled multiple dose ascending study in healthy participants and patients with asthma. Healthy participants will be enrolled in Part A and patients with asthma in Part B: 1.
- Trial name
- NCT06947408
- Testing
- IBI3002
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.
Asthma
Study of Fluticasone Propionate Multidose Dry Powder Inhaler Compared With Fluticasone Propionate/Salmeterol Multidose Dry Powder Inhaler
This study is to evaluate the safety and efficacy of fluticasone propionate and fluticasone propionate salmeterol in pediatric participants with a documented history of persistent asthma.
- Trial name
- NCT02980133
- Testing
- Fluticasone Propionate, Fluticasone Propionate/Salmeterol
- Where
- 118 sites in United States, Georgia and 3 more
- Volunteers
- 841 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Chronic Asthma
The Safety and Effectiveness of MK0476 (Montelukast) in Patients With Chronic Asthma (0476-388)
This study will test the safety and effectiveness of a range of doses of MK0476 (montelukast) compared to placebo on improved lung function in patients with chronic asthma.
- Trial name
- NCT00739297
- Testing
- Comparator: montelukast
- Volunteers
- 68 people
- Sponsor
- Organon and Co
Asthma
A Blinded Study To Examine The Ability Of PF-610,355 To Open The Airways In Asthmatic Patients.
A study to determine the ability of different doses of PF-610,355 to open the airways in asthmatic patients by comparison with placebo and a marketed drug that also opens the airways in asthmatic patients.
- Trial name
- NCT00468975
- Testing
- PF-610,355, Salmeterol
- Where
- 6 sites in Germany, Sweden and 1 more
- Volunteers
- 42 people
- Sponsor
- Pfizer
Asthma
A Study to Assess the Effect of QAW039 in Non-atopic Asthmatic Patients
The purpose of the study was to assess the clinical effect of QAW039 in non-atopic asthmatics taking low dose Inhaled Corticosteroid (ICS) as background therapy.
- Trial name
- NCT01836471
- Testing
- QAW039, Fluticasone 250 mcg, Fluticasone 100 mcg
- Where
- 76 sites in United States, Belgium and 8 more
- Volunteers
- 345 people
- Sponsor
- Novartis Pharmaceuticals
Asthma
A Study of Lebrikizumab (MILR1444A) in Adult Patients With Asthma Who Are Inadequately Controlled on Inhaled Corticosteroids
This is a randomized, double-blind, placebo-controlled study to evaluate the effects of lebrikizumab in patients with asthma who remain inadequately controlled while on chronic therapy with inhaled corticosteroids (ICS).
- Trial name
- MILLY (NCT00930163)
- Testing
- lebrikizumab (MILR1444A)
- Volunteers
- 218 people
- Sponsor
- Genentech, Inc.
Asthma
Results Of Patient Rated Asthma Control Test In Comparison To Diary Card Data
The majority of asthma patients are not well controlled, despite the availability of asthma medication that could effectively treat the disease.
- Trial name
- NCT00363480
- Testing
- Salmeterol/Fluticasone 50/250 mcg, Salbutamol 100 mcg, DISKUS™ powder inhalers
- Where
- 32 sites in Germany
- Volunteers
- 221 people
- Sponsor
- GlaxoSmithKline
Asthma
Effect on Fenoterol Metered Dose Inhaler on the Beta-receptor Population on Lymphocytes in Patients With Bronchial Asthma
The aim of the study was to compare the effect of fenoterol metered dose inhaler with disodium cromoglycate (DSCG) metered dose inhaler on the lymphocyte β2-receptor population as well as on the clinical findings in patients with…
- Trial name
- NCT02177370
- Testing
- Fenoterol MDI, DSCG MDI
- Volunteers
- 19 people
- Sponsor
- Boehringer Ingelheim
Safety in Asthma Patients
Phase 1 Study Evaluating Safety and Pharmacokinetics of ASY202 in Adults With Asthma
This is a phase 1 study, randomized, double-blind, placebo-controlled, 2 treatment, 2 period crossover study to evaluate the pharmacokinetics, safety, and tolerability of a single inhaled dose of ASY202 in adults with stable…
- Trial name
- NCT07665892
- Testing
- ASY202
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Aspeya, Inc.
Asthma
Study of Efficacy and Safety of LOU064 in Inadequately Controlled Asthma Patients
This was a proof-of-concept study to evaluate the efficacy of LOU064 in patients with inadequately controlled asthma. All subjects were randomized with 3:2 ratio to receive LOU064 100 mg once daily or LOU064 matching placebo for…
- Trial name
- NCT03944707
- Testing
- LOU064 100 mg
- Where
- 19 sites in United States, Argentina and 3 more
- Volunteers
- 76 people
- Sponsor
- Novartis Pharmaceuticals
Asthma
A Comparison of Mometasone Furoate DPI Versus Budesonide DPI in Budesonide DPI in Asthmatics (Study P04880)
This study will be an open-label, parallel-group comparison of Mometasone Furoate Dry Powder Inhaler (MF-DPI) 200 mcg once daily in the evening with two puffs vs.
- Trial name
- NCT00442117
- Testing
- mometasone furoate dry powder inhaler, Budesonide DPI
- Volunteers
- 180 people
- Sponsor
- Organon and Co
Pulmonary Disease, Chronic Obstructive
A Study To Investigate The Effect Of Inhaling A Single Dose Of GW642444M In Asthmatic Patients
This study will involve the use of a new compound, GW642444 that is being developed for the treatment of asthma and chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT00463697
- Testing
- GW642444H (100mcg), GW642444M (25, 100 & 400 mcg)
- Where
- 3 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- GlaxoSmithKline
Asthma
Bi 671800 in Asthmatic Patients on Inhaled Corticosteroids
To investigate the effectiveness and safety of BI 671800 given in the morning (AM), evening (PM) or twice daily (b.i.d.) compared too placebo as add on therapy to inhaled corticosteroid in symptomatic asthma patients.
- Trial name
- NCT01090024
- Testing
- BI 671800
- Where
- 14 sites in United States
- Volunteers
- 108 people
- Sponsor
- Boehringer Ingelheim
Asthma, Airway Obstruction
Single-dose Crossover Study to Investigate Pharmacodynamics of AZD3199
The purpose of this study is to investigate the pharmacodynamics of single doses of AZD3199 in asthmatic patients.
- Trial name
- NCT00736489
- Testing
- AZD3199, Formoterol
- Where
- 4 sites in Denmark, Sweden
- Volunteers
- 37 people
- Sponsor
- AstraZeneca
Asthma, Respiratory Candidiasis
The Effect of PC945 on Aspergillus or Candida Lung Infections in Patients With Asthma or Chronic Respiratory Diseases
This study tests the effects of an experimental drug PC945 in people with asthma or other chronic respiratory diseases whose lungs are infected by Aspergillus fungi and Candida yeasts.
- Conditions
- Asthma, Respiratory Candidiasis, Respiratory Aspergillosis, COPD
- Trial name
- NCT03745196
- Testing
- PC945
- Where
- 4 sites in United Kingdom
- Volunteers
- 13 people
- Sponsor
- Pulmocide Ltd
Asthma
The Comparison of Electronic Auscultation Coupled With CALSA and FRI; Repeatability of FRI Biomarkers
CALSA will be compared with FRI and the repeatability of the FRI parameters will be tested in a group of healthy volunteers and asthma patients.
- Trial name
- NCT02228018
- Testing
- CT-scan
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- FLUIDDA nv
Asthma
Safety Study of Nebulized RNS60 to Treat Asthma.
The purpose of this study is two-fold. First, to determine whether nebulized RNS60 is safe in healthy human subjects and in subjects with mild asthma, in a single-dose administration.
- Trial name
- NCT01057498
- Testing
- RNS60, RNS60 - single dose
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Revalesio Corporation
Asthma
Benralizumab Patient Access Programme Study: Retrospective Study in UK Severe Asthma Centres
Retrospective secondary data collection observational chart review study. Data collection and analysis will be performed on a cohort of patients who have previously been enrolled on the BPAP.
- Trial name
- BPAP (NCT05932849)
- Testing
- Benralizumab
- Where
- 8 sites in United Kingdom
- Volunteers
- 276 people
- Sponsor
- AstraZeneca
Asthma
Efficacy Study of SYN006 HFA MDI in Asthma Patients
The objective of the study is to evaluate the dose response of SYN006 HFA MDI, which is a combination drug product of budesonide and procaterol hydrochloride, in asthma patients.
- Trial name
- NCT02162784
- Testing
- Budesonide/Procaterol, 180/10mcg X1, Budesonide/procaterol 180/10 mcg X 2, Albuterol HFA MDI 100mcg X2
- Where
- 3 sites in Taiwan
- Volunteers
- 39 people
- Sponsor
- Intech Biopharm Ltd.