Clinical trials: Asymptomatic
Breast Cancer Detection, Dense Breast Parenchyma
Delphinus SoftVue™ ROC Reader Study (DMT SV RRS3)
The purpose of this multi-reader, multi-case (MRMC) reader study is to evaluate reader performance when SoftVue™ automated breast ultrasound and screening mammography are combined, compared to screening mammography alone, in…
- Conditions
- Breast Cancer Detection, Dense Breast Parenchyma, Benign Breast Findings, Normal Breast Screening
- Trial name
- DMT SV RRS3 (NCT04260620)
- Testing
- Reading of Automated Breast Ultrasound in conjunction with Screening Mammography
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Delphinus Medical Technologies, Inc.
Atrial Fibrillation, Pulsed-field Ablation
Pulsed-field Ablation for Patients With Asymptomatic Non-paroxysmal Atrial Fibrillation
The goal of the study is to test the hypothesis whether the treatment of patients with asymptomatic non-paroxysmal AF based on catheter ablation will be superior than conservative approach consisting of electrical cardioversion…
- Conditions
- Atrial Fibrillation, Pulsed-field Ablation, Functional Exercise Testing
- Trial name
- NCT06166524
- Testing
- Catheter ablation for atrial fibrillation using pulsed-field energy, Conservative arm
- Where
- Czechia
- Volunteers
- 124 people
- Sponsor
- Charles University, Czech Republic
Total Hip Replacement
A Comparison of Large Diameter Metal Heads vs. Small Diameter Metal Heads vs/ Dual Mobility Total Hip Replacements
Does having a large diameter metal on polyethylene total hip replacement increase metal ion release. Larger metal heads are thought to have increased torsional forces on the trunion which would like release more metal ions.
- Trial name
- NCT02049892
- Testing
- Metal Ion Levels
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Mayo Clinic
HIV Infections
Double-Blind Study of Timunox (Thymopentin) in Asymptomatic HIV-Infected Patients Receiving Either Mono (AZT or ddI) or Combination (AZT / ddI or AZT / ddC) Anti-Retroviral Therapy
To confirm results from a previous study in which the combination of thymopentin plus zidovudine ( AZT ), an antiretroviral agent, slowed disease progression in HIV-infected asymptomatic patients.
- Trial name
- NCT00002109
- Testing
- Thymopentin, Stavudine, Zidovudine
- Where
- 50 sites in United States, Puerto Rico
- Sponsor
- Immunobiology Research Institute
Prostate Cancer
Study of Abiraterone Acetate Plus Prednisone in Patients With Chemo-naive Metastatic Castration-Resistant Prostate Cancer
The purpose of this study is to demonstrate the safety and effectiveness of abiraterone acetate when co-administered with prednisone in patients with chemo-naive metastatic castration resistant prostate Cancer (mCRPC).
- Trial name
- NCT01591122
- Testing
- Abiraterone acetate and prednisone
- Where
- 22 sites in China, Malaysia and 2 more
- Volunteers
- 313 people
- Sponsor
- Janssen Research & Development, LLC
Injuries and Wounds
the Role of Total Body Imaging in Asymptomatic Pediatric Trauma Patients
Whole body imaging has no role in asymptomatic pediatric trauma patients
- Trial name
- NCT00424736
- Testing
- whole body CT scan
- Volunteers
- 100 people
- Sponsor
- Assaf-Harofeh Medical Center
Atrial Fibrillation
Evaluation of the Incidence of Cerebral Lesions Post Pulmonary Vein Ablation Catheter (PVAC)
The purpose of the study is to determine the rate of diffusion weighted (DW)-MRI cerebral lesions following a Pulmonary Vein Ablation Catheter (PVAC) ablation procedure performed using best practices, including optimized…
- Trial name
- ERACE (NCT01520532)
- Testing
- Magnetic Resonance Imaging (MRI)
- Where
- 7 sites in Belgium, Canada and 3 more
- Volunteers
- 60 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Atrial Fibrillation
Atrial Fibrillation Symptoms and Pain Sensitization
Atrial fibrillation (AF) is the most common sustained arrhythmia and the number of patients with AF is expected to increase substantially in the coming decades.
- Trial name
- NCT04649437
- Testing
- Quantitative sensory testing
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Region Örebro County
HIV
A Phase 2 Study Of PF-00232798 In HIV Positive Patients
To assess the viral load response, safety, tolerability and pharmacokinetics of multiple oral doses of PF 00232798 in HIV-positive patient volunteers.
- Trial name
- NCT00495677
- Testing
- PF-00232798
- Where
- 2 sites in Germany
- Volunteers
- 43 people
- Sponsor
- Pfizer
Twin; Pregnancy, Affecting Fetus or Newborn
Effect of Cervical Cerclage With Vaginal Progesterone in Asymptomatic Twin Pregnancies With a Sonographic Short Cervix
The objective of the present study is to evaluate the effectiveness of vaginal progesterone and cervical cerclage each alone and in combination in improving gestational age in twin pregnancy and its subsequent impact on perinatal…
- Trial name
- NCT03781466
- Testing
- Cervical cerclage, vaginal progesterone
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Aswan University Hospital
Pre-Eclampsia, Asymptomatic Bacteriuria
Prevalence of Asymptomatic Bacteriuria Among Pregnant Women With Pre-eclampsia in Women Health Hospital Assiut University
Pre-eclampsia is a hypertensive disorder of pregnancy that can lead to significant health complications for both the mother and the fetus.
- Trial name
- NCT07866196
- Volunteers
- 129 people
- Sponsor
- Assiut University
Forward Head Posture
Efficacy of Adding Scapular Stabilization Exercises to Postural Correctional Exercises on on Forward Head Posture
The aim of this study is to investigate efficacy of adding Scapular Stabilization Exercises to postural correctional exercises on Endurance of cervical flexor and extensor muscles on Asymptomatic forward head posture.
- Trial name
- FHP (NCT04959942)
- Testing
- scapular stabilization exercise, postural correction exercise, advice
- Volunteers
- 60 people
- Sponsor
- Cairo University
Irriversible Pulpitis
Analyzing the Impact of Occlusal Reduction on the Pain Following Root Canal Therapy in Molar Teeth With and Without Pain in Turkish Patients.
Introduction: This study aimed to compare the intensity of postoperative pain after single-visit root canal treatment of symptomatic or asymptomatic teeth following occlusal reduction.
- Trial name
- NCT06953856
- Testing
- occlusal reduction
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Postoperative Dental Pain, Root Canal Sealers
Effect of Different Root Canal Sealers on Postoperative Pain
This randomized clinical trial aimed to evaluate postoperative pain following the use of bioceramic and epoxy resin-based root canal sealers in combination with the continuous wave of condensation technique (CWCT), addressing a…
- Conditions
- Postoperative Dental Pain, Root Canal Sealers, Asymptomatic Irreversible Pulpitis
- Trial name
- NCT06726837
- Testing
- Postoperative pain - 6th hour, Postoperative pain - 24th hour, Postoperative pain - 48th hour
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Dicle University
Pregnant Women
Malaria In Pregnancy in Central India
The present study is planned to be conducted at a district level women and children's hospital at Nagpur with the following objectives: Objectives: i) To assess the prevalence of asymptomatic malaria infection with all four…
- Trial name
- MIP (NCT03955263)
- Where
- India
- Volunteers
- 887 people, healthy volunteers welcome
- Sponsor
- Lata Medical Research Foundation, Nagpur
Aged, Asymptomatic Condition
Classification of the Sagittal Profile of the Spine in Asymptomatic Elderly Subjects
Principal aim The main purpose of the study is to describe the distribution of the sagittal profile in elderly subjects in order to bridge the gap present in this type of screening, evaluated in the literature for adults only…
- Trial name
- EOS60 (NCT03237039)
- Testing
- X-ray examination, fall-risk assessment, gait cycle analysis
- Where
- Italy
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Postoperative Pain, Asymptomatic Apical Periodontitis
Effect of Rotary File Number on MB2 Canal Negotiation and Postoperative Pain
This randomized controlled clinical trial aims to evaluate the effect of the number of rotary files on working length negotiation and postoperative pain in the second mesiobuccal (MB2) canals of maxillary first molars.
- Trial name
- MB2-PAIN (NCT07091981)
- Testing
- One Curve Rotary File, Perfect Super System Minimal Invasive Kit, VDW Rotate
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Mehmet Adıgüzel
Aortic Valve Stenosis, Diastolic Dysfunction
Danish National Randomized Study on Early Aortic Valve Replacement in Patients With Asymptomatic Severe Aortic Stenosis
The purpose of this study is to examine the impact of early surgery in patients with asymptomatic severe aortic valve stenosis with signs of subclinical LV dysfunction despite preserved LVEF, with a watchfull waiting approach.
- Trial name
- DANAVR (NCT03972644)
- Testing
- Aortic valve replacement
- Where
- Denmark
- Volunteers
- 1,700 people
- Sponsor
- Odense University Hospital
Lymphogranuloma Venereum, no Anorectal Symptoms
Multicentre Study Evaluating the Efficacy of a 7-day Course of Doxycycline for the Treatment of Asymptomatic Anal Lymphogranuloma Venereum.
Lymphogranuloma venereum (LGV) is a sexually transmitted infection (STI) caused by the L genotypes of C. trachomatis. Proctitis is the main clinical manifestation of infection in the current LGV epidemic.
- Conditions
- Lymphogranuloma Venereum, no Anorectal Symptoms, Doxycycline
- Trial name
- SHORT-LGV (NCT07767422)
- Testing
- Doxycline
- Where
- 14 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Bordeaux
Gout and Hyperuricemia
Phase II Dose Finding Study of RDEA3170 Versus Placebo in Japanese Patients With Gout or Asymptomatic Hyperuricemia
This study is to examine the hypothesis that administration of RDEA3170 to Japanese patients with gout or asymptomatic hyperuricemia in doses of 5 mg, 7.5 mg, 10 mg, 12.5 mg and 15 mg once daily, respectively will result in…
- Trial name
- NCT02078219
- Testing
- RDEA3170, Allopurinol
- Where
- 14 sites in Japan
- Volunteers
- 204 people
- Sponsor
- AstraZeneca