Clinical trials: Asymptomatic Condition
Infection Viral
COVID-19 Biological Samples Collection
The coronavirus disease 2019 (COVID-19) outbreak is now considered as a public health emergency of international concern by the World Health Organization.
- Trial name
- COLCOV19-BX (NCT04332016)
- Testing
- biological samples collection
- Where
- France
- Volunteers
- 615 people
- Sponsor
- University Hospital, Bordeaux
Hyperuricemia
Imagery as Biomarker of Gout
The objective of this study is to determine whether MSU crystal deposits visualized on ultrasound and/or DECT are associated with the development of symptomatic gout (according to ACR 2015 / EULAR criteria) over 5 years in…
- Trial name
- TIGER (NCT05434858)
- Testing
- Dual-energy CT (DECT) and ultrasound
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Lille Catholic University
Prostate Cancer
Bicalutamide Compared With Observation Followed by Bicalutamide Plus Either Goserelin or Orchiectomy in Treating Patients With Prostate Cancer
RATIONALE: Testosterone can stimulate the growth of cancer cells. Bicalutamide and goserelin may fight prostate cancer by reducing the production of testosterone.
- Trial name
- NCT00014586
- Testing
- bicalutamide, goserelin acetate, orchiectomy
- Where
- Germany
- Volunteers
- 110 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Covid19
Study to Select the Dose and Evaluate Safety and Efficacy of Monoclonal Antibody in Adult With Recently Diagnosed Asymptomatic to Moderately Severe COVID-19.
MAD0004J08, the experimental drug, is a potent neutralizing IgG1 monoclonal antibody (mAb) targeting the spike protein of SARS-CoV-2. MAD0004J08 blocks viral attachment and entry into human cells and neutralizes the virus.
- Trial name
- NCT04952805
- Testing
- MAD0004J08
- Where
- 14 sites in Italy
- Volunteers
- 800 people
- Sponsor
- Toscana Life Sciences Sviluppo s.r.l.
Asymptomatic Hypertension
Innovative Approaches to Hypertension Management in High-Risk Emergency Department Populations
This single-center, single-arm quasi-experimental study will assess the feasibility and acceptability of a community health worker (CHW)-led intervention to address social determinants of health (SDOH) among emergency department…
- Trial name
- aHTN-Manage (NCT07539597)
- Testing
- Community Health Worker engagement
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hyperuricemia or Gout
Clinical Efficacy Trial of Burdock Root Extract in Patients With Asymptomatic Hyperuricaemia
Multicentre, double-blind, randomized, placebo-controlled trial of the clinical efficacy of burdock root extract in patients with asymptomatic hyperuricemia, with the primary objective to assess the efficacy of the use of burdock…
- Trial name
- NCT07002762
- Testing
- Burdock ( Arctium lappa L.) root extract in a form of a nutritional additive
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- OMNIFARMA LLC
Mutation, Neoplasms
Utility of Plasma Circulating Tumor DNA (ctDNA) in Asymptomatic Subjects for the Detection of Neoplastic Disease
Pathway Genomics Corporation (Pathway Genomics), a San Diego, California company, is involved in the development and validation of new molecular diagnostic assays for the analysis of circulating tumor deoxyribonucleic acid (DNA)…
- Trial name
- H1000 (NCT02612350)
- Testing
- ctDNA Analysis for the Detection of Genetic Mutations
- Where
- United States
- Volunteers
- 1,106 people, healthy volunteers welcome
- Sponsor
- Pathway Genomics
Prostate Cancer Metastatic
A Randomized, Double-blind, Phase 3 Efficacy Trial of PROSTVAC-V/F +/- GM-CSF in Men With Asymptomatic or Minimally Symptomatic Metastatic Castrate-Resistant Prostate Cancer
The purpose of this study is to determine whether PROSTVAC alone or in combination with GM-CSF is effective in prolonging overall survival in men with few or no symptoms from metastatic, castrate-resistant prostate cancer.
- Trial name
- Prospect (NCT01322490)
- Testing
- PROSTVAC-V, PROSTVAC-F, GM-CSF
- Where
- 220 sites in United States, Australia and 14 more
- Volunteers
- 1,297 people
- Sponsor
- Bavarian Nordic
Obstructive Sleep Apnea-hypopnea Syndrome
The Role of Inflammatory Markers in OSAHS-Related White Matter Lesions and Asymptomatic Lacunar Infarction
This retrospective observational study aims to investigate the potential role of inflammatory markers associated with Obstructive Sleep Apnoea-Hypopnoea Syndrome (OSAHS) in the pathogenesis of white matter lesions (WML) and…
- Trial name
- NCT07061990
- Testing
- Polysomnography (PSG), Brain Magnetic Resonance Imaging (MRI), Serum Inflammatory Marker Measurement
- Where
- China
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Yanpeng Li
Clostridium Difficile, Inflammatory Bowel Diseases
Seroprevalence of Anti-bodies Against Clostridium Difficile Toxins and Prevalence of Asymptomatic Carriage of Clostridium Difficile in IBD Patients.
The objective of this study to evaluate the seroprevalence of anti-bodies against C. difficile toxins A and B and the asymptomatic carriage of C.
- Trial name
- NCT03889808
- Testing
- Determination of serum anti-toxin Abs for C. difficile
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari de Bellvitge
Covid19, Corona Virus Infection
A Follow On Community Testing Study To Evaluate The Performance of the Lucira COVID-19 All-In-One Test Kit
To evaluate the performance of the FDA EUA authorized Lucira COVID-19 All-In-One Test Kit for the qualitative detection of SARS-CoV-2 virus in nasal swab samples as compared to a known high sensitivity EUA RT-PCR among…
- Trial name
- NCT04720235
- Testing
- Lucira COVID-19 All-In-One test kit
- Where
- United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Lucira Health Inc
Wolf Parkinson White Syndrome, Arrythmias
Wolf-Parkinson-White Syndrome and Asymptomatic Pre-excitation in Africa (a Multicenter WPW African Registry)
The purpose of this prospective observational study is to characterize the clinical profile of patients with WPW syndrome and patients with asymptomatic WPW pattern on ECG in different African countries and how these patients are…
- Trial name
- NCT06260384
- Testing
- electrocardiogram
- Where
- Egypt
- Volunteers
- 500 people
- Sponsor
- Ain Shams University
Myocardial Ischemia
Peripheral Endothelial Function and Coronary Status in Asymptomatic Diabetic Patients
Silent myocardial ischemia is usual in type 2 diabetic patients and associated with coronary stenoses and endothelial dysfunction or both.
- Trial name
- PEFDIA (NCT00685984)
- Where
- France
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Wolff-Parkinson-White Syndrome
Risk Assessment in Patients With Symptomatic- and Asymptomatic Preexcitation
Prospective cohort study including 150 patients with pre-excitation on ECG referred to our clinic for risk assessment. There will be equal numbers of symptomatic and asymptomatic patients included in the study.
- Trial name
- RASAP (NCT03301935)
- Testing
- Electrophysiology testing and exercise stress testing
- Where
- Sweden
- Volunteers
- 168 people
- Sponsor
- Karolinska University Hospital
HIV Infections
A Phase I Multicenter Clinical Trial to Evaluate the Safety and Immunogenicity of Immuno-AG Recombinant HIV gp160 in Asymptomatic HIV Seropositive Individuals
To determine the safety and immunogenicity of vaccinia-derived HIV-1 recombinant envelope glycoprotein (gp160) in asymptomatic HIV-infected adult volunteers.
- Trial name
- NCT00000633
- Testing
- gp160 Vaccine (Immuno-AG), Hepatitis B Vaccine (Recombinant)
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Asymptomatic P.Falciparum Malaria
Artemisia Annua Infusion for the Treatment of Asymptomatic Plasmodium Falciparum Infection
The goal of this clinical trial is to determine whether Artemisia annua dried leaves, used as an infusion, can treat individuals with malaria parasites but no symptoms.
- Trial name
- ART-CT001 (NCT07819825)
- Testing
- Artemisia Annua Leaf, Centaurii herba
- Where
- Gabon
- Volunteers
- 20 people
- Sponsor
- Centre de Recherche Médicale de Lambaréné
Aortic Stenosis
Identification of Parameters in rapId-proGression Subgroup Patients With Moderate Aortic Stenosis
The investigators aim to identify all clinical, biological, echo and imagistic parameters that predispose to increased progression rates in a prospective observational trial which will include ONLY patients with moderate AS, with…
- Trial name
- ENIGMAS (NCT01575249)
- Where
- Romania
- Volunteers
- 200 people
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Orthopedic Disorder
Developmental Hip Dysplasia by Ultrasonographic Screening of Asymptomatic Infants at Assiut University Hospital
Developmental dysplasia of the hip (DDH), formerly known as congenital dislocation of the hip, comprises a spectrum of abnormalities that include abnormal acetabular shape (dysplasia) and malposition of the femoral head.
- Trial name
- NCT03476915
- Testing
- ultrasound examination of the hip joint
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Assiut University
Sars-CoV2, COVID-19
Oral Favipiravir Compared to Placebo in Subjects With Mild COVID-19
The objective of this study is to evaluate the efficacy of oral favipiravir plus standard of care treatment (SOC) compared with placebo plus SOC in reducing the duration of shedding of SARS-CoV2 virus in patients with mild or…
- Trial name
- NCT04346628
- Testing
- Favipiravir, Standard of care treatment
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Stanford University
Stenosis
Natural History of Asymptomatic Superior Mesenteric Arterial Stenosis.
The aim of this study was to evaluate asymptomatic superior mesenteric artery (SMA) stenosis prognosis according to the presence of coeliac artery (CA) and/or inferior mesenteric artery (IMA) associated stenosis.
- Trial name
- NCT04785105
- Testing
- No intervention
- Where
- France
- Volunteers
- 77 people
- Sponsor
- Hospices Civils de Lyon