Clinical trials: Asynchrony, Patient-Ventilator
Brain Injuries, Mechanical Ventilation
Patient-ventilator Asynchrony in Patients With Brain Injury
Mechanical ventilation is an important support strategy for critically ill patients. It could improve gas exchange, reduce the work of breathing, and improve patient comfort.
- Trial name
- NCT03212482
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jian-Xin Zhou
Respiration, Artificial
Patient-ventilator Asynchrony During Mechanical Invasive Assisted-ventilation in Pediatric Patients
The purpose of this study is to document the prevalence and type of asynchronies incidence during invasive mechanical ventilation in pediatric patients breathing under pressure support.
- Trial name
- NavPed-Inv (NCT01193023)
- Testing
- Pressure Support, NAVA
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University Hospital, Geneva
Patient-Ventilator Interaction, Asynchrony, Patient-Ventilator
Standardising Terminology, Classification, Diagnostic Recognition and Reporting of Patient-ventilator Interactions: Protocol for an International Delphi Consensus Study
Patient-ventilator interaction describes how a mechanically ventilated patient's breathing effort aligns with ventilator support.
- Trial name
- INTERACT (NCT07638540)
- Testing
- Modified Delphi consensus survey
- Where
- Kuwait
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al Adan Hospital Kuwait
COP, Non-invasive Ventilation
Patient-ventilator Asychrony During Non-invasive Ventilation When COPD Patients Doing Exercise
Pulmonary rehabilitation programmes including aerobic exercise training have strong evidence of effectiveness in improving exercise capacity, dyspnoea and HRQL in patients with COPD.
- Conditions
- COP, Non-invasive Ventilation, Pulmonary Rehabilitation
- Trial name
- NCT04054622
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Guangzhou Medical University
Respiratory Failure
A Pilot Study Investigating the Detection of Episodes of Severe Patient-Ventilator Asynchrony
The goal of this study is to determine what percent of severe patient-ventilator asynchrony is detected in mechanically ventilated patients in the adult ICU and to determine delays in detecting those asynchronies by the staff…
- Trial name
- NCT04550871
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Autonomous Healthcare, Inc.
Ventilator Associated Events, Asynchrony, Patient-Ventilator
Synchrony-Optimized Non-Invasive Ventilation Education Program and ICU Patients
The aim of this clinical trial is to find out whether a synchrony-optimized education program for non-invasive ventilation (NIV) can help ICU patients use their ventilator more effectively and improve their comfort, symptoms, and…
- Conditions
- Ventilator Associated Events, Asynchrony, Patient-Ventilator, Intensive Care (ICU), Noninvasive Ventilation
- Trial name
- NCT07291622
- Testing
- SYNC-NIV
- Volunteers
- 92 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Asynchrony, Patient-Ventilator, ARDS
Comparison of Different Methods to Calculate Pendelluft by Electrical Impedance Tomography in Mechanically Ventilated Patients
The Pendelluft phenomenon is an important cause of lung damage in spontaneously breathing mechanically ventilated patients since it considerably increases the stress on the lung parenchyma in the dependent areas.
- Conditions
- Asynchrony, Patient-Ventilator, ARDS, Respiratory Insufficiency, Respiratory Effort-Related Arousal | Patient | Respiratory Measures and Ventilator Management
- Trial name
- NCT06494215
- Testing
- Pressure Support Variation and Calculation of Respiratory Mechanics
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- University of Sao Paulo General Hospital
Patient-Ventilator Asynchrony, Mechanical Ventilation Complication
Nurse Education to Reduce Patient-Ventilator Asynchrony in the PICU
A prospective cluster-randomized quality improvement trial was conducted to evaluate whether a structured nurse education program on ventilator waveform interpretation and alarm management reduces patient-ventilator asynchrony in…
- Conditions
- Patient-Ventilator Asynchrony, Mechanical Ventilation Complication, Nurse Education
- Trial name
- NCT07273487
- Testing
- Nurse Education on Ventilator Waveform and Alarm Management
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Mechanical Ventilation Complication
Automated Detection of Patient Ventilator Asynchrony Using Pes Signal
Rationale: Patient-ventilator asynchrony (PVA) in mechanical ventilation is associated with adverse patient outcome such as a prolonged stay in the ICU and even mortality.
- Trial name
- NCT06186557
- Testing
- No intervention
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Leiden University Medical Center
Automatic Adjustmen of Inspiratory Triger and Cycling-off
IntelliCycleTM 2.0 Improved Patient-ventilator Asynchrony During PSV
Pressure Support Ventilation use Expiratory triggering sensitivity (Esense) to transfer inspiration to expiration, the value of Esense is fixed.
- Trial name
- NCT04091269
- Testing
- automatic adjustmen of inspiratory triger and cycling-off based on waveform and PSV with fixed Esence
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Southeast University, China
Pediatric Acute Respiratory Failure
Neurally Adjusted Ventilatory Assist (NAVA) vs. Pressure Support in Pediatric Acute Respiratory Failure
It is hypothesized that the use of Neurally Adjusted Ventilatory Assist (NAVA) compared to pressure support to provide noninvasive ventilation to children will result in a decrease in the number of children with moderate to…
- Trial name
- NiNAVAped (NCT01873521)
- Testing
- Non invasive ventilation
- Where
- Spain
- Volunteers
- 350 people
- Sponsor
- Hospital Universitario La Paz
Respiratory Failure
Patient-Ventilator Dyssynchrony: How is the Effect of Management?
Although patient-ventilator asynchrony is a frequent phenomenon, its course following management is unknown. As the aid of a data recording system, we try to observe the consequence of patient-ventilator asynchrony following…
- Trial name
- NCT00683072
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Cheng-Kung University Hospital
Respiratory Effort, Respiratory Distress Syndrome
The Association Between Respiratory Effort Parameters During the First 48 Hours With Clinical Outcomes in Mechanically Ventilated Patients: A Prospective Observational Study.
Over-assisted mechanical ventilation (MV) is linked to respiratory muscle disuse atrophy, while under-assisted MV can lead to patient self-inflicted lung injury (P-SILI) or respiratory muscle injuries.
- Conditions
- Respiratory Effort, Respiratory Distress Syndrome, Lung Mechanics
- Trial name
- EFFORT-1 (NCT06433076)
- Where
- Thailand
- Volunteers
- 163 people
- Sponsor
- Ramathibodi Hospital
Thoracic Surgery
Patient-ventilator Asynchrony in Conventional Ventilation Modes During Short-term Mechanical Ventilation After Cardiac Surgery
This study evaluates the effects of VCV, PCV and PSV ventilatory modes during the immediate postoperative period on the variables resulting from regional and global pulmonary electrical impedance and diaphragmatic mobility, as…
- Trial name
- NCT03141216
- Testing
- VCV+PSV, PCV+PSV
- Where
- Brazil
- Volunteers
- 19 people
- Sponsor
- Universidade Federal de Pernambuco
Acute Respiratory Failure, Pediatric Respiratory Distress Syndrome
Closed-loop Synchronization Versus Conventional Synchronization
A prior research indicated that asynchrony between the patient and ventilator occurred in 33 percent of 19,175 breaths, and was seen in every patient.
- Trial name
- CHESTSIPP (NCT05731024)
- Testing
- close-loop synchronization controller with SPONT mode, Conventional synchronization settings with SPONT mode
- Where
- 5 sites in Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Mechanical Ventilation, Patient-Ventilator Asynchrony
Patient-Ventilator Asynchrony: Occurence and Clinical Impact in Usual Care
The goal of this observational study is to unravel the occurence, impact and relations of Patient-Ventilator Aynchrony (PVA) in mechanically ventilated patients.
- Trial name
- PVA-detection (NCT07624786)
- Testing
- PVA classification software
- Where
- 3 sites in Netherlands
- Volunteers
- 110 people
- Sponsor
- Erasmus Medical Center
ARDS (Acute Respiratory Distress Syndrome), Respiratory Failure
Development and Prospective Validation of the AutoEIT Foundation Model for ARDS
Acute Respiratory Distress Syndrome (ARDS) is a highly heterogeneous condition, making precision mechanical ventilation challenging.
- Conditions
- ARDS (Acute Respiratory Distress Syndrome), Respiratory Failure, Mechanical Ventilation, Ventilator-induced Lung Injury (VILI)
- Trial name
- NCT07898319
- Testing
- AutoEIT Model Training, AutoEIT Blinded Validation
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Ruijin Hospital
Critical Illness
The Impact of Higher Positive End Expiratory Pressure on Patient-Ventilator Asynchrony
Patient-ventilator asynchrony is known to frequently occur during lung protective ventilation in patients with ARDS. Previous clinical studies showed that patient-ventilator asynchrony was associated with worse outcome in ICU.
- Trial name
- NCT04951960
- Testing
- Higher PEEP setting, Lower PEEP setting
- Where
- Japan
- Volunteers
- 10 people
- Sponsor
- Osaka University
Patient/Ventilator Asynchrony
The Use of Neurally Adjusted Ventilatory Assist (NAVA) Versus Pressure Support During Asynchrony in Children
The aim of the current study is to compare the application neurally adjusted ventilatory assist (NAVA) to optimize pressure support ventilation in 12 pediatric patients.
- Trial name
- NAVAChildren (NCT01159106)
- Testing
- Pressure Support Ventilation, Neurally adjusted ventilatory assist (NAVA)
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Hospital Universitario La Paz
Reverse Triggering, Patient Ventilator Dyssynchrony
Intrinsic Respiratory Rate Assessment During Mechanical Ventilation to Accelerate Spontaneous Breathing and Extubation
The goal of this study is to identify patients with reverse triggering who's the potential to breath spontaneously is hidden because of the ventilator management strategy by performing a simple 30sec-test with includes reducing…
- Trial name
- INTRINSIC (NCT06445049)
- Testing
- brief test
- Volunteers
- 70 people
- Sponsor
- Unity Health Toronto