Clinical trials: Atelectasis
Respiratory Distress Syndrome in Premature Infant, Surfactant Deficiency Syndrome Neonatal
Feasibility Study - Neofact
For therapy of respiratory distress syndrome (RDS) in premature babies, there are several established options. An important therapeutic aspect is the tracheal administration of exogenous surfactant into the child's lung.
- Trial name
- NCT04086095
- Testing
- Neofact application aid
- Where
- 2 sites in Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Tuebingen
Surfactant Deficiency Syndrome Neonatal, Respiratory Distress Syndrome in Premature Infant
Fast Assessment of Surfactant Deficiency in Preterm Infants to Speed up Treatment - Validation Study
The aim is to re-validate a FTIR spectroscopy test for measuring lung maturity/Respiratory Distress Syndrome (RDS) before conducting a RCT using this test to guide surfactant treatment of preterm infants.
- Trial name
- FAST2 (NCT05615428)
- Testing
- LS-ratio
- Where
- 3 sites in Denmark
- Volunteers
- 68 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Lung Injury, Postoperative Complications
Ventilation During Cardiopulmonary Bypass
Postoperative pulmonary dysfunction (PPD) is a widely reported complication of cardiopulmonary bypass (CPB) although there is improvement in perioperative management, that leads to increased morbidity and mortality in cardiac…
- Conditions
- Lung Injury, Postoperative Complications, Pulmonary Collapse
- Trial name
- NCT04962542
- Testing
- ventilation
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Lung Collapse
Brochoscopic Intervention Versus Conventional Management in Acute Lung Collapse in the Pediatric Intensive Care Unit
This prospective RCT at Cairo University Children Hospitals enrolls critically ill pediatric patients (intubated, NIV, or post-extubation) with lung atelectasis unresponsive to 48 hours of conventional recruitment.
- Trial name
- picu (NCT07383129)
- Testing
- bronchoscope, chest physiotherapy and suction
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Patients With ASA Status I-III Scheduled for Elective Surgery
The Air Test: A New Simple, Non-invasive Method to Diagnose Anesthesia-induced Atelectasis
Anesthesia-induced atelectasis persist in the postoperative period but are not usually diagnosed because imaging techniques are required.
- Trial name
- NCT02650037
- Testing
- Air Test
- Where
- Spain
- Volunteers
- 181 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Neonatal Respiratory Distress
Urine NT-ProBNP in Neonatal Respiratory Distress
There is a need for a biochemical marker in addition to clinical condition which will help the physician to understand the clinical progress of the disease.
- Trial name
- NT-proBNP (NCT02020993)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ankara University
Ventilator-Induced Lung Injury, Lung Ventilator
Respiratory Mechanics During One-lung Ventilation
Intraoperative lung protective ventilatory strategy has been widely recognized to reduce postoperative pulmonary complications in laparotomy and laparoscopic surgeries.
- Conditions
- Ventilator-Induced Lung Injury, Lung Ventilator, One-lung Ventilation
- Trial name
- NCT04519606
- Testing
- Optimal lung compliance during OLV
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- E-DA Hospital
Lung Collapse, One-Lung Ventilation
Physiology of Lung Collapse Under One-Lung Ventilation: Underlying Mechanisms
Lung isolation technique and one-lung ventilation (OLV) are the mainstays of thoracic anesthesia. Two principal lung isolation techniques are mainly use by clinicians, the double lumen tubes (DLT) and the bronchial blockers (BB).
- Conditions
- Lung Collapse, One-Lung Ventilation, Thoracic Surgery, Video-Assisted
- Trial name
- PLC-OLV (NCT02919267)
- Testing
- Double lumen tube, Bronchial blocker
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Laval University
Postoperative Atelectasis, Lung Recruitment
Lung Recruitment Maneuvers for Postoperative Atelectasis Prevention After Idiopathic Adolescents' Scoliosis Correction
The investigators hypothesized that an ultrasound-guided lung recruitment maneuvers would be more effective in preventing postoperative atelectasis than conventional alveolar recruitment after surgical correction of idiopathic…
- Conditions
- Postoperative Atelectasis, Lung Recruitment, Scoliosis; Adolescence
- Trial name
- NCT05325463
- Testing
- conventional lung recruitment, ultrasound- guided lung recruitment
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Atelectasis, Block
Effect Posterior QLB on Atelectasis
We aimed to investigate the effect of posterior quadratus lumborum block on postoperative atelectasis in inguinal hernia surgery in pediatric patients.
- Conditions
- Atelectasis, Block, Pediatrics, Quadratus Lumborum Block
- Trial name
- NCT04830280
- Testing
- posterior quadratus lumborum block
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Transient Tachypnea of the Newborn, Neonatal Respiratory Distress
Efficacy of Misoprostol in Prevention of Neonatal Respiratory Morbidity in Parturient at Early Term Elective Caesarian Section
Neonatal respiratory morbidities represent a common group of post natal complications including respiratory distress syndrome, transient tachypnea of newborn, and persistent pulmonary hypertension of newborn.
- Trial name
- NCT04780412
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Atelectasis, Pediatric Anesthesia
Atelectasis After Inhalation or Intravenous Induction in Pediatric Anesthesia
Children have a highly compliant chest wall and atelectasis formation occurs often during pediatric anesthesia. Inhalation induction is commonly performed in pediatric anesthesia but it is still unclear if this can have an effect…
- Trial name
- AtelectLUS (NCT06069414)
- Testing
- Type of anesthesia induction
- Where
- Italy
- Volunteers
- 326 people
- Sponsor
- Vittore Buzzi Children's Hospital
Postoperative Pulmonary Complications (PPCs), Cardiac Surgery With Sternotomy
Effect of Positioning and ACBT on Pulmonary Complications After Cardiac Surgery
The goal of this quasi-experimental clinical trial is to learn if position management combined with the Active Cycle of Breathing Techniques (ACBT) works to reduce postoperative pulmonary complications in adult patients…
- Conditions
- Postoperative Pulmonary Complications (PPCs), Cardiac Surgery With Sternotomy, Atelectasis, Postoperative Pneumonia
- Trial name
- P-ACBT (NCT07612033)
- Testing
- Structured Position Management Protocol, Active Cycle of Breathing Techniques (ACBT)
- Where
- Egypt
- Volunteers
- 124 people
- Sponsor
- Assiut University
Lung Collapse
HFNC for Induction During Bariatric Surgery Patients.
This study aims to compared the effects of high flow nasal during the induction and during the weaning of anesthesia on intraoperative and postoperative oxygenation and postoperative atelectasis in obese patients undergoing…
- Trial name
- NCT03155711
- Testing
- HFNC group, Standard group
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Pulmonary Atelectasis
Ventilation During Cardiopulmonary Bypass (CPB) for Cardiac Surgery
During most types of heart surgery cardiopulmonary bypass (CPB) is used. CPB enables blood to be directed away from the heart and the lungs and pumped through the body while the heart is not beating.
- Trial name
- NCT02070445
- Where
- Canada
- Sponsor
- McMaster University
Respiratory Distress Syndrome (Neonatal), Respiratory Distress of Newborn
How Different Levels of CPAP Affect Oxygen Delivery and Lung Expansion in Preterm Infants
With this study, it is expected to learn more about preterm babies on breathing support with nasal continuous positive airway pressure (nCPAP).
- Trial name
- NCT07674953
- Testing
- Effective oxygen delivery and lung expansion measurement
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Arkansas
Pulmonary Atelectasis, Postoperative Complications
poStoperative Anesthesia Care: Facial Mask vs Hfnc and Thoracic Ultrasound for Reduction of Atelectasis Incidence
The primary aim of this study is to assess the efficacy of post-operatory HFNC in reducing the incidence of hypoxemia after gynecological oncology surgery, compared to the standard application of O2 through a Venturi mask; The…
- Conditions
- Pulmonary Atelectasis, Postoperative Complications, Gynecologic Cancer, Anesthesia
- Trial name
- SAMURAI (NCT04566419)
- Testing
- HFNC - Airvo 2, Oxygen
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Ventilator-associated Lung Injury, Atelectasis
Comparing Innovative and Traditional Ventilation Strategies on Atelectasis and Prognosis in Elderly Patients
This study was divided into two parts, taking elderly patients undergoing general anesthesia surgery as the research subjects, through factorial design: 1.
- Conditions
- Ventilator-associated Lung Injury, Atelectasis, Postoperative Pulmonary Complications
- Trial name
- NCT06021249
- Testing
- Traditional ventilation strategies, Traditional lung-protective ventilation strategies, Innovative lung-protective ventilation strategies
- Where
- 3 sites in China
- Volunteers
- 304 people
- Sponsor
- Fujian Medical University Union Hospital
Acute Respiratory Distress Syndrome
EIT Assessment of Overdistension in ARDS Patients in Prone Position
Mechanical ventilation in ARDS requires protective ventilation with low VT and PEEP. PEEP titration can improve lung recruitment in the dependent lung but with a risk of overdistension in the non-dependant lung.
- Trial name
- DISTIE-DV (NCT06536543)
- Testing
- Acute Respiratory Distress Syndrom (ARDS) treated with Prone Position (PP) equipped with Electrical Impedance Tomography (EIT)
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Bordeaux
Artificial Intelligence, Lung Diseases
Retrospective Study of Carebot AI CXR Performance in Preclinical Practice
The purpose of this study is to describe the design, methodology and evaluation of the preclinical test of Carebot AI CXR software, and to provide evidence that the investigated medical device meets user requirements in…
- Conditions
- Artificial Intelligence, Lung Diseases, Pneumothorax, Pleural Effusion
- Trial name
- NCT05594485
- Testing
- Carebot AI CXR
- Where
- Czechia
- Volunteers
- 127 people
- Sponsor
- Carebot s.r.o.