Clinical trials: Athlete Heart
Atrial Fibrillation
Effects of Detraining in Endurance Athletes With Atrial Fibrillation
Atrial fibrillation (AF) affects more than 43 million people worldwide, but specific exercise recommendations do not exist for this group of patients.
- Trial name
- NEXAF (NCT04991337)
- Testing
- Detraining group, Control group
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Vestre Viken Hospital Trust
Atrial Fibrillation (AF)
Understanding the Increased Risk of Atrial Fibrillation in Athletes: a Case-control Study
Exercise is beneficial to heart health, however, there appears to be a 'U' shaped relationship where too much exercise may increase the risk of an irregular heart rhythm, called atrial fibrillation.
- Trial name
- AFLETES-ECG (NCT06844656)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Athletes, Atrial Fibrillation
Pulmonary Vein Isolation in Athletes
Pulmonary vein isolation (PVI) has become a common and effective treatment for paroxysmal and persistent atrial fibrillation (AF), particularly in patients with drug-refractory disease.
- Conditions
- Athletes, Atrial Fibrillation, Catheter Ablation
- Trial name
- NCT03226847
- Testing
- Pulmonary Vein Isolation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The Cleveland Clinic
Autonomic Dysfunction
PD2i Analysis of Heart Rate Variability in Competitive Sports
This is a double blind observational analysis of changes in heart rate variability using PD2i analyser in competitive athletes during strenuous exercise and competition.
- Trial name
- PACA (NCT01249248)
- Testing
- PD2i Analyzer
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Sudden Cardiac Arrest, Sudden Cardiac Death
Sudden Cardiac Arrest Related to Sport in Young and Value of the Genetic Assessment: a French Prospective Register
The increased risk of sudden cardiac arrest (SCA) or sudden cardiac death (SCD) related to vigorous physical activity is well-documented.
- Trial name
- RESOUDRE (NCT06642168)
- Testing
- Whole exome sequencing to detect myocardial genetic mutations (SCA group only)
- Where
- 26 sites in France
- Volunteers
- 80 people
- Sponsor
- Rennes University Hospital
Arrhythmogenic Right Ventricular Cardiomyopathy
Athlete's Heart or Arrhythmogenic Right Ventricular Cardiomyopathy: Contribution of Exercise Cardiovascular Magnetic Resonance (CMR)
Prospective, nonrandomized, single-center, comparative study to define if right ventricular (RV) contractile reserve assessed by exercise CMR helps to improve the differential diagnosis between pathological and physiological…
- Trial name
- CA2VD (NCT05024708)
- Testing
- Cardiac exercises and tests
- Where
- France
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Athletes Heart
Semmelweis Sport Study
The aim of the present proposal is to investigate the development of distinct morphological, functional, biochemical and molecular aspects of short- and long-term sport-induced changes in the heart, to get a better understanding…
- Trial name
- NCT03025737
- Where
- Hungary
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Semmelweis University Heart and Vascular Center
Inherited Cardiac Conditions, Sudden Cardiac Arrest
Using Heart Electrical Signals to Study How Well Treatments Prevent Dangerous Heart Rhythms in Active People
The goal of this observational study is to learn if two specific heart electrical signal patterns can help in detecting the risk of dangerous heart rhythms in athletes, and to see if exercise-based tests can be used instead of…
- Conditions
- Inherited Cardiac Conditions, Sudden Cardiac Arrest, Ventricular Arrhythmia, Athlete
- Trial name
- ULTIMATE-A (NCT07014579)
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Athlete's Heart
Echocardiographic Characteristics of High Endurance Israeli Athletes
The purpose of this study is to characterize the cardiac adaptive changes of professional Israeli bicyclists by using echocardiography.
- Trial name
- NCT00634335
- Where
- Israel
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Cardiac Function in Young Athletes
Study to Assess the Effect of OXYJUN on Ejection Fraction and Markers of Cardiovascular Injury
Young athletes are usually regarded as a special subgroup of healthy individuals with a unique lifestyle who are apparently invulnerable and often capable of extraordinary physical achievement.
- Trial name
- Enduoxy (NCT02207101)
- Testing
- E-OJ-01 (OXYJUN)
- Where
- India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Athlete Heart
Interaction Between Intraventricular Flow and Cardiac Mechanics Using 3D Echocardiography in Athletes and Sedentary Subjects
Exercise-induced cardiac remodeling, known as the "athlete's heart," corresponds to morphological and functional adaptations of the left ventricle in response to prolonged physical training.
- Trial name
- CARDIO-3D (NCT07363993)
- Where
- 2 sites in France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Avignon
Ventricular Premature Complexes, Atrial Premature Complexes
Oral Magnesium Supplementation in Athletes With Premature Ventricular Contractions or Premature Atrial Contractions.
Magnesium is a mineral which is essential to many of the processes which happen in the body. This includes normal function of muscles; including the heart.
- Trial name
- NCT04186728
- Testing
- Magnesium glycinate
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Neck Pain, Heart Rate Variability
Compare the Effects of Different AVNS Parameters on Neck Pain, HRV, Balance in Collegiate Atheletes
This study looks at how auricular vagus nerve stimulation (AVNS) affects neck pain, heart rate variability, and balance in college athletes, additionally, if different settings of auricular vagus nerve stimulation (AVNS) affect…
- Conditions
- Neck Pain, Heart Rate Variability, Balance
- Trial name
- NCT06450483
- Testing
- Auricular vagus nerve stimulation
- Where
- United Arab Emirates
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Oxidative Stress, Athletes Heart
The Effects of Dark Chocolate Implementation in Elite Athletes
Dark chocolate (DC) is rich in epicatechin which augments nitric oxide (NO) production through endothelium-dependent influences.
- Conditions
- Oxidative Stress, Athletes Heart, Physical Activity
- Trial name
- NCT03288623
- Testing
- Dark Chocolate (85% cocoa), White/Milk chocolate (<35% cocoa)
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- University of Roma La Sapienza
Healthy
The North Sea Race Endurance Exercise Study
Competitions such as marathon running and endurance cycling events are increasingly popular and represent an important motivation for sustaining training among leisure-time athletes.
- Trial name
- NEEDED (NCT02166216)
- Where
- Norway
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF
Coronary Artery Disease
Coronary Artery Disease (CAD) in Women Marathon Runners
The aim of this study is to determine the effects of extreme fitness in women. The incidence of coronary artery disease observed via multislice computed tomography (MSCT) angiogram will be compared with age and risk-matched…
- Trial name
- NCT00918372
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Minneapolis Heart Institute Foundation
Atrial Fibrillation, Stroke
AFLETES-MRI: A Cardiac and Cerebral Magnetic Resonance Imaging Study in Athletes With Atrial Fibrillation
Participation in exercise improves cardiovascular health. However, long-term endurance exercise may increase the risk of an irregular heart rhythm called atrial fibrillation (AF).
- Trial name
- AFLETES-MRI (NCT06424171)
- Testing
- Cardiac and brain magnetic resonance imaging.
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Diagnoses Disease
HEARTBEAT-TROP. Polyethylene Glycol Precipitation to Unmask Macrotroponin
Troponin elevation can, among others, be due to myocardial infarction, acute inflammation or structural heart disease. Formation of macrocomplexes against troponin is an underestimated cause for persistent troponin elevation.
- Trial name
- MACRO-TROP (NCT07726420)
- Testing
- Polyethylene glycol precipitation, Transthoracic echocardiography
- Where
- Germany
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Sudden Cardiac Death, Sudden Cardiac Arrest
Low QRS Voltages in Young Healthy Individuals and Athletes
There is some limited evidence that reduced size of electrical complexes/traces of the heart on the electrocardiogram (ECG) may be associated with scarring in the heart muscle, which may predispose to serious life-threatening…
- Conditions
- Sudden Cardiac Death, Sudden Cardiac Arrest, Sudden Cardiac Death Due to Cardiac Arrhythmia, Arrhythmogenic Right Ventricular Cardiomyopathy
- Trial name
- NCT05799833
- Testing
- Cardiovascular magnetic resonance scan - 3T scanner (Siemens Vida)
- Where
- United Kingdom
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Imperial College London
HIIT
Effect of Different Work-to-rest Ratios During Simulated Taekwondo Combat on Blood Lactate, Heart Rate and Perceptual Responses in Elite Taekwondo Athletes
This randomized cross-over study measured physiological and perceptual responses of taekwondo athletes following a free combat and combats with different W:R ratios. This study was carried out with 4 visits.
- Trial name
- NCT07395414
- Testing
- Free combat, 1:2 work to rest ratio, 2:1 work to rest ratio
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kastamonu University