Clinical trials: Athlete Heart
Atrial Fibrillation (AF)
Performance After Cardiac Ablation in Endurance Athletes for Atrial Fibrillation
The relationship between exercise and atrial fibrillation (AF) seems to follow a J-shaped curve: while moderate activity reduces AF risk, both insufficient and excessive endurance exercise increase susceptibility.
- Trial name
- PACE-AF (NCT07726056)
- Testing
- Ablation
- Where
- 5 sites in Australia, Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital of Leuven Leuven
Cardiac Remodeling, Ventricular
Intracardiac Flow Remodeling in Athletes
The uncertainty concerning the onset and the extent of cardiac remodeling in response to intensive training hinders medical evaluation by physician.
- Trial name
- INFINITE (NCT03076788)
- Testing
- electrocardiogram and echocardiography
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Sports Accident, Athletes Heart
Lithuanian Atletes' Aortic Diameter
Recent developments in football have seen the sudden death of young football player due to aortic rupture hence reinforcing the controversy of football as a field with substantial risk for sudden cardiac arrest and death.
- Trial name
- NCT03656861
- Testing
- Physical load
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Agne Slapsinskaite
Stroke, Not Specified as Hemorrhage or Infarction, Angina Pectoris
Clinical Study of Medicinal Product Cardionat® Using in Health Athlete Volunteers
The objective of this study is to evaluate the long-term plasma and urine pharmacokinetic parameters of Cardionat®, capsules 250 mg, when used in healthy athlete volunteers. The study consists of four steps: Step 1.
- Trial name
- NCT02758912
- Testing
- оral intake of study drug capsules; study drug - Cardionat ® (trimethylhydrazinium propionate dihydrate), oral capsules 250 mg
- Where
- Russia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Burnasyan Federal Medical Biophysical Center
Nervous System Diseases, Dehydration
Assessment of Heart Rate Variability, Performance and Dehydration in Muay Thai Athletes
Known as "Thai boxing," Muay Thai utilizes a combination of upper limb strikes (such as punches and elbow strikes) as well as lower limb strikes (such as kicks and knee strikes), and is thus referred to as the "art of eight…
- Trial name
- NCT06338501
- Testing
- Specifical Functional Training Exercises
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Centro Universitário Augusto Motta
Cardiovascular Morbidity, Androgen Deficiency
Cross-sectional Study of 1200 Recreational Athletes With Former or Current Use of Androgenic Anabolic Steroids
Overarching aim of project Performance and image enhancing drugs (PIEDs) are pharmacological agents acquired illicitly to improve physical strength and endurance as well as to obtain a leaner and more muscular appearance.
- Conditions
- Cardiovascular Morbidity, Androgen Deficiency, Heart Failure
- Trial name
- FIDODK/BIC (NCT05178537)
- Testing
- AAS users
- Where
- Denmark
- Volunteers
- 1,200 people
- Sponsor
- Jan Frystyk
Recovery Strategies After Simulated 400-meter Sprint in University Athletes
Effect of Combined Active Recovery and Foam Rolling Enhance Lactate Clearance and Reduce Muscle Soreness Following a Simulated Running Competition
This study investigates the effects of combining Active Recovery (AR) and Foam Rolling (FR) on blood lactate, heart rate, and muscle soreness in competitive 400-meter sprint athletes.
- Trial name
- ARFR (NCT07439523)
- Testing
- Active Recovery + Foam Rolling, Active Recovery Only
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Surabaya State University
Oxidative Stress, Athletes Heart
The Effects of Dark Chocolate Implementation in Elite Athletes
Dark chocolate (DC) is rich in epicatechin which augments nitric oxide (NO) production through endothelium-dependent influences.
- Conditions
- Oxidative Stress, Athletes Heart, Physical Activity
- Trial name
- NCT03288623
- Testing
- Dark Chocolate (85% cocoa), White/Milk chocolate (<35% cocoa)
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- University of Roma La Sapienza
Heart Failure, Athletes Heart
Cardiopulmonary and Right Ventricular Function in Health and Disease
The primary objective of this research protocol is to advance the understanding of cardiopulmonary and right ventricular (RV) performance among individuals with cardiomyopathy (heart failure with reduced ejection fraction…
- Trial name
- NCT04147299
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Colorado, Denver
Muscle; Fatigue, Heart
FACEFI : Cardiac Fatigue During Intense Exercises - Pilot Study
To attest if a cardiac fatigue appears (and to measure it if it does) during intense physical exercises in two groups of subjects: Canoeists from a training center of the French canoeing team during an intensive session of three…
- Trial name
- FACEFI (NCT02126891)
- Testing
- Tests
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Healhty
Autonomic and Peripheral Neurochemical Responses to Maximal Rowing Exercise
The goal of this observational study is to characterize autonomic, neuroendocrine, and peripheral neurochemical responses to maximal rowing exercise and early recovery in highly trained male athletes.
- Trial name
- NCT07661953
- Testing
- Maximal 6,000-m rowing ergometer test
- Where
- Poland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Ventricular Function, Left
Assessment of Cardiac Involvement of Common Cold in High Performing Athletes by Cardiac Magnetic Resonance Imaging (MRI)
Cardiovascular magnetic resonance (CMR) imaging will be used to assess the impact of common colds and physical training in high-performing athletes. Healthy individuals from the general public will serve as a comparison group.
- Trial name
- NCT00739895
- Testing
- Cardiac magnetic Resonance study, Blood testing
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Athletes, Cyclists
Acute Physiological Effects of Full-Body Far-Infrared Emitting Textiles on Young Road Cyclists
Road cycling is a sport characterized by long, high-intensity training sessions. Cyclists train and compete in varying temperatures, which can affect their performance.
- Trial name
- NCT07503977
- Testing
- FIR
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- University of Palermo
Ventricular Premature Complexes, Atrial Premature Complexes
Oral Magnesium Supplementation in Athletes With Premature Ventricular Contractions or Premature Atrial Contractions.
Magnesium is a mineral which is essential to many of the processes which happen in the body. This includes normal function of muscles; including the heart.
- Trial name
- NCT04186728
- Testing
- Magnesium glycinate
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Exercise
Ischemic Preconditioning in Endurance Athletes
The aim of this study is to investigate the effect of remote ischemic preconditioning on biochemical and functional indices of cardiac function induced by a 30 km run in healthy trained long distance runners.
- Trial name
- NCT01774461
- Testing
- Remote ischemic preconditioning
- Where
- Netherlands
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Athletes Heart
Changing the Pulse of Athletics: Applying a Standardized Cardiac Athletic Screening for NCAA Athletes
This is a study supported by Duke Sports Cardiology and Duke Sports Medicine with the intent to enhance the cardiovascular screening of collegiate athletes from a regional to nationally recognized program to understand and…
- Trial name
- NCT03150940
- Testing
- ECG, bedside cardiac ultrasound
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Duke University
Athlete Heart, Arrhythmias, Cardiac
Reverse Cardiac Remodeling Among Elite Athletes After Short and Long-term Detraining
Exercise has many well-documented effects in the prevention or treatment of disease, but recently some studies have raised awareness of the possible negative effects of too much exercise.
- Trial name
- Remod (NCT05555849)
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Bispebjerg Hospital
Coronary Artery Disease
Coronary Artery Disease (CAD) in Women Marathon Runners
The aim of this study is to determine the effects of extreme fitness in women. The incidence of coronary artery disease observed via multislice computed tomography (MSCT) angiogram will be compared with age and risk-matched…
- Trial name
- NCT00918372
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Minneapolis Heart Institute Foundation
Covid19
Cardiac Assessment After Covid-19 Disease in Elite Altheltic Population
COVID-19 infection coud induce cardiac injuries. Before returning to sport, cardiac evaluation is recommended by sports federations, based on the precautionary principle and the opinion of expert consensus.
- Trial name
- CADE (NCT04653857)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Montpellier
Right Ventricular Dysfunction, Cardiopulmonary Diseases
Right Heart and Lung Blood Flow During Exercise (RIGHT-NET 2.0)
RIGHT-NET 2.0 is a multicenter observational study with a retrospective-prospective design that builds on the original RIGHT-NET study.
- Conditions
- Right Ventricular Dysfunction, Cardiopulmonary Diseases, Pulmonary Hypertension
- Trial name
- RIGHT-NET 2 (NCT07851610)
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- IRCCS SYNLAB SDN