Clinical trials: Atopic Rhinitis, open to volunteers
Allergic Rhinitis
Study on the Effect and Mechanism of Lupatadine Fumarate in the Treatment of Allergic Rhinitis
In China, the prevalence of allergic rhinitis reaches 17.6% and is increasing year by year, seriously affecting the quality of life of patients. Some patients still cannot be effectively treated.
- Trial name
- NCT06709092
- Testing
- lupatadine fumarate (Luso®, Yangzijiang Pharmaceuticals)
- Where
- 2 sites in China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cheng Lei
Rhinitis, Allergic
Study on the Mechanism of ZhenQiFuZheng in the Treatment of Allergic Rhinitis Based on Intestinal Flora and Metabolites
ZhenQi FuZheng granules has been used to improve the immune function of human body, protect the bone marrow and adrenal cortex function and promote the recovery of positive function in traditional Chinese medicine care…
- Trial name
- NCT06427577
- Testing
- ZhenQi FuZheng granules (ShiDaiYangGuang)
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Allergic Rhinitis, Vasomotor Rhinitis
Comparison of the Effects for Lightening the Shiners Among Different Treatments for Rhinitis
Background: Shiners are caused when blood and other fluids accumulate in the infraorbital groove. It develops resulting from lots of problems.
- Trial name
- NCT05348148
- Testing
- Oral Levocetirizine, Combined Intranasal Mometasone Furoate with oral Levocetirizine, Combined Intranasal Mometasone Furoate with oral Levocetirizine plus intranasal Oxymetazoline
- Where
- Taiwan
- Volunteers
- 450 people
- Sponsor
- Camillians Saint Mary's Hospital Luodong
Allergic Rhinitis
Efficacy and Safety of Arbidol in the Treatment of Allergic Rhinitis
The most important treatment for AR is topical nasal medications (including nasal corticosteroids, nasal antihistamines, nasal decongestants, and nasal saline irrigation etc.), which are still limited.
- Trial name
- NCT06462417
- Testing
- Arbidol
- Where
- 2 sites in China
- Volunteers
- 15 people
- Sponsor
- Zheng Liu
Knee Osteoarthritis; Insomnia; Cervical Spondylosis; Chronic Low Back Pain; Allergic Rhinitis
Validating Blinding Maintenance of a Sham-Sensitization Control Design for Sensitization Acupuncture Trials
This study is the clinical validation component of a broader research program developing a randomized controlled trial (RCT) comparing sensitization acupuncture (an individualized technique in which treatment points are selected…
- Trial name
- NCT07868224
- Testing
- Sensitization Acupuncture, Traditional Acupuncture
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jiangxi University of Traditional Chinese Medicine
Allergic Rhinitis, Allergic Rhinoconjunctivitis
Specific Immunotherapy With Mannan-Conjugated Allergoids for HDM-Allergic Rhinitis/Rhinoconjunctivitis_MM09-SIT-063.
The goal of this clinical trial is to learn whether EP-088_MM09 works to treat house dust mite allergy. It will also assess the treatment's safety.
- Conditions
- Allergic Rhinitis, Allergic Rhinoconjunctivitis, Allergic Asthma
- Trial name
- NCT07904195
- Testing
- EP-088_MM09
- Where
- 16 sites in Portugal, Spain
- Volunteers
- 250 people
- Sponsor
- Inmunotek S.L.
Allergic Rhinitis
Huandao Conditioning Application for Allergic Rhinitis Treatment
The goal of this clinical trial is to learn if the Huandao Conditioning Application works to treat allergic rhinitis in adults. It will also learn about the safety of this application.
- Trial name
- NCT06818526
- Testing
- Huandao Conditioning Application
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
SAR
A Prospective Study of Stapokibart Injection in Patients With Seasonal Allergic Rhinitis (SAR)
This study is an open label, prospective study to evaluate the safety of Stapokibart Injection in subjects with SAR.
- Trial name
- NCT07459556
- Testing
- Stapokibart
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Chengdu Kangnuoxing Biopharma,Inc.
Allergen Immunotherapy
Phase 1, First in Human (FIH), Open-Label, Single-Arm, Ascending Dose Study to Assess the Safety, Tolerability and Preliminary Immunogenicity of ITI-9001 in Japanese Patients With Japanese Red Cedar (JRC) Pollinosis
This is a Phase 1, first-in-human clinical trial to test a new treatment called ITI-9001 for people with allergies to Japanese Red Cedar (JRC) pollen-a common cause of seasonal allergies in Japan.
- Trial name
- NCT07726147
- Testing
- ITI-9001
- Where
- Japan
- Volunteers
- 45 people
- Sponsor
- Immunomic Therapeutics, Inc.
Seasonal Allergic Rhinitis (SAR), Allergic Rhinitis
Evaluation of the Efficacy, Safety, and Tolerability of PL-14 Allergy Blocker Compared to Saline Spray in Patients With Seasonal Allergic Rhinitis
This study is designed to evaluate the efficacy, safety, and tolerability of PL-14 Allergy Blocker compared to saline spray in adults with Seasonal Allergic Rhinitis (SAR).
- Trial name
- NCT07588672
- Testing
- PL-14 Allergy Blocker, Ayr® Saline Nasal Mist
- Where
- 5 sites in United States
- Volunteers
- 120 people
- Sponsor
- Polyrizon Ltd.
Seasonal Allergic Rhinitis
Study of CM310 in Patients With Uncontrolled Seasonal Allergic Rhinitis
Allergic rhinitis (AR) is a non-infectious chronic inflammatory disease of the nasal mucosa mainly mediated by immunoglobulin E after exposure to allergens in atopic individuals.
- Trial name
- MEGREZ (NCT06300203)
- Testing
- Interleukin-4 receptor responders
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Tongren Hospital
Rhinitis, Allergic
Biomarker Screening for Immunotherapy Response Evaluation Using Microneedle Patch in Patients with Allergic Rhinitis
Allergic rhinitis is a disease in which the nasal mucous membrane overreacts to allergens, resulting in symptoms such as spasmodic and repetitive sneezing, rhinorrhea, and stuffy nose, and can be treated with immunotherapy for…
- Trial name
- MIST (NCT05922176)
- Testing
- Evaluation of clinical indicators, Sample collection before& after immunotherapy, Sample collection before& after immunotherapy
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Allergic Rhinitis, Sinusitis
Harnessing Digital Medicine to Improve Allergic Rhinitis Management in Primary Care (DMAR)
This study aims to evaluate the effectiveness of digital tools in managing allergic rhinitis (AR) in primary care settings. AR is a common condition that affects many people's quality of life.
- Trial name
- DMAR (NCT06603935)
- Testing
- QHSLab Digital Tools (AME and ARIS)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- QHSLab, Inc.
Seasonal Allergic Rhinitis, SAR
A Phase III Study to Assess the Efficacy and Safety of PG-011 Nasal Spray in Adults With Moderate to Severe Seasonal Allergic Rhinitis
The study is a multicenter, randomized, double-blind, placebo-controlled seamless and adaptive-designed phase IIb/III study encompassing a phase IIb and a phase III component, phase IIb is a dose-ranging part and has been done…
- Trial name
- Pumecitinib (NCT07146126)
- Testing
- PG-011 nasal spray 0.6%(twice daily)
- Where
- 38 sites in China
- Volunteers
- 600 people
- Sponsor
- Prime Gene Therapeutics Co., Ltd.
Allergic Rhinitis (Disorder), Electroacupuncture
The Treatment of Moderate to Severe Allergic Rhinitis With Electroacupuncture Combined With Microneedle Knife
Based on the inclusion and exclusion criteria, patients with allergic rhinitis who meet the requirements are selected as trial subjects, and the efficacy is clarified in a randomized controlled design trial.
- Conditions
- Allergic Rhinitis (Disorder), Electroacupuncture, Microneedle Knife
- Trial name
- NCT06890260
- Testing
- Electroacupuncture combined with Microneedle Knife, Cetirizine hydrochloride tablets combined with nasal budesonide spray.
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Pengfei Qiu
Allergic Rhinitis
A Prospective, Randomized, Controlled Study Comparing the Efficacy of Intranasal Corticosteroids (INCS) Combined With Intranasal Antihistamines (INAH) and INCS Combined With Oral Antihistamines (OAH) in the Treatment of Moderate to Severe Allergic Rhinitis Symptoms
Through prospective exploration of the efficacy of intranasal corticosteroids (INCS) combined with intranasal antihistamines (INAH) and INCS combined with oral antihistamines (OAH) in treating moderate to severe allergic rhinitis…
- Trial name
- NCT07294326
- Testing
- Intranasal corticosteroids (INCS) combined with oral antihistamines (OAH) used for treatment, Intranasal corticosteroids (INCS) combined with nasal antihistamines (INAH) used for treatment.
- Volunteers
- 50 people
- Sponsor
- China-Japan Union Hospital
Perennial Allergic Rhinitis
Trial of JYB1904 Injection in Patients With Perennial Allergic Rhinitis
This Phase II Trial is Meant to Evaluate the Efficacy, and Safety of JYB1904 Injection in Patients With Perennial Allergic Rhinitis.
- Trial name
- NCT07459452
- Testing
- JYB1904
- Volunteers
- 135 people
- Sponsor
- Jemincare
Perennial Allergic Rhinitis (PAR)
Study of CM512 Injection in Patients With Perennial Allergic Rhinitis on Background Therapy
This is a randomized, double-blind, placebo-parallel controlled phase II study to evaluate the safety and efficacy of CM512 in patients with perennial allergic rhinitis on background therapy
- Trial name
- NCT07890350
- Testing
- CM512
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Keymed Biosciences Co., Ltd.
Rhinitis, Allergic
Microbial Study of Sublingual Immunotherapy Spray in Patients With Allergic Rhinitis
The incidence of allergic rhinitis (AR) in Chinese adults was reported to be as high as 24.1% and 16.8% in children. The current symptomatic treatment has the disadvantage of poor efficacy and cannot change the natural course of…
- Trial name
- NCT06741787
- Testing
- Patients desensitized by sublingual spray
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Rhinitis Allergic
PollenVax Subcutaneous Immunotherapy for Mugwort Pollen-Induced Allergic Rhinitis
This study evaluates the effectiveness and safety of PollenVax, a subcutaneous allergen immunotherapy (SCIT) drug developed for the treatment of allergic rhinitis and asthma caused by mugwort (Artemisia vulgaris) pollen.
- Trial name
- NCT07563439
- Testing
- Recombinant Artemisia vulgaris allergen Art v 1 with Montanide ISA-51 adjuvant
- Where
- Kazakhstan
- Volunteers
- 138 people
- Sponsor
- Kazakh National Agrarian University