Clinical trials: Atorvastatin
Multiple Sclerosis
Immunotherapy With BHT-3009 Alone or Combined With Atorvastatin in Patients With Multiple Sclerosis
This research study is being done to evaluate the safety of BHT-3009 alone and when combined with atorvastatin (Lipitor) in patients with multiple sclerosis (MS).
- Trial name
- NCT00103974
- Testing
- BHT-3009-01
- Where
- 4 sites in United States, Canada
- Volunteers
- 30 people
- Sponsor
- Bayhill Therapeutics
Acute Kidney Injury
Safety and Efficiency Study of Loading Dose Atorvastatin in Cardiac Surgery
Statins were reported to have pleiotropic effects including antiinflammatory, anti-oxidative stress effects and stabilise plaque in some conditions.
- Trial name
- NCT01547455
- Testing
- Atorvastatin(Lipitor)
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Peking Union Medical College
Osteoarthritis of the Knee
Hydroxychloroquine/Atorvastatin in the Treatment of Osteoarthritis (OA) of the Knee
The purpose of this study of a combination therapy of hydroxychloroquine and atorvastatin is to learn about the effects in inflammation and pain in patients with Osteoarthritis of the knee.
- Trial name
- NCT01645176
- Testing
- Hydroxychloroquine/Atorvastatin
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Stanford University
Coronary Heart Disease
Assessment of the Lipid Lowering Effect of Rosuvastatin Compared to Atorvastatin in Subjects With Coronary Heart Disease
The purpose of this study is to compare the efficacy between two lipid lowering treatments, rosuvastatin (10-40 mg) and atorvastatin (20-80 mg) in reducing low-density lipoprotein cholesterol (LDL-C) levels after 16 weeks of…
- Trial name
- NCT00235950
- Testing
- Rosuvastatin or atorvastatin or simvastatin and clopidogrel
- Where
- 18 sites in Sweden
- Volunteers
- 255 people
- Sponsor
- AstraZeneca
Hypercholesterolemia
A Clinical Trial Study to Evaluate Efficacy and Safety of Atorvastatin in Korean Patients With Hypercholesterolemia
The purpose of this study is to compare the efficacy and safety of atorvastatin generic product with reference drug.
- Trial name
- NCT01081548
- Testing
- atorvastatin
- Where
- South Korea
- Volunteers
- 17 people
- Sponsor
- Yonsei University
Paroxysmal Atrial Fibrillation
Statin and PAF in Patients With Pacemaker
Statin could decrease AF burden
- Trial name
- NCT00201552
- Testing
- Statin
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital
Healthy Controls
The Effect of Short-term Atorvastatin Treatment on Immune Responses to Pneumovax 23
The purpose of this research study is to: Improve the effectiveness of vaccinations by identifying the effect of cholesterol medication, statins, on immune responses.
- Trial name
- StatVax (NCT02097589)
- Testing
- Atorvastatin, Pneumovax 23
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Florida
Diabetes, Type 2
Evaluating Atorvastatin With Omega-3 Fatty Acids in Cardiovascular Risk Reduction in Patients With Type 2 Diabetes
The AFORRD trial is asking three important questions: What proportion of people with Type 2 Diabetes are likely to be treated satisfactorily with a fixed dose of a statin that lowers blood cholesterol levels to help reduce the…
- Trial name
- AFORRD (NCT00141232)
- Testing
- Atorvastatin and Omega-3 fatty acids
- Where
- 59 sites in United Kingdom
- Volunteers
- 810 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Coronary Artery Disease
Ezetimibe and Atorvastatin Therapy on TCFA
After successful coronary angiography and OCT examination, patients with TCFAs in non-culprit, mild-to-moderate stenotic lesions will be enrolled.
- Trial name
- NCT02588235
- Testing
- Ezetimibe and Atorvastatin, Atorvastatin
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xijing Hospital
Cardiovascular Diseases, Coronary Artery Disease
Study On Liprimar (Atorvastatin) In Patients With Coronary Heart Disease (CHD) And High Risk Of Cardiovascular Complications
In which CHD patients with high risk of CV complications are different doses of LIPRIMAR used? For this purpose, data on hyperlipidemia will be elicited over and above the basic nosographic and demographic data, concomitant…
- Trial name
- LIGHT (NCT00993915)
- Testing
- Atorvastatin
- Volunteers
- 687 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Thrombosis, Prevention
Re-STOP DVT: Reload of High Dose Atorvastatin for Preventing Deep Vein Thrombosis in Statin Users
Reload of high dose statin may have potential for preventing deep vein thrombosis (DVT) in patients on statin undergoing total knee replacement arthroplasty.
- Conditions
- Thrombosis, Prevention, Surgery
- Trial name
- Re-STOP DVT (NCT01063426)
- Testing
- High dose Atorvastatin+enoxaparin, Enoxaparin
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Hallym University Medical Center
Chronic Periodontitis
Atorvastatin in the Treatment of Mandibular Degree II Furcation Defects
ABSTARCT Background: Atorvastatin is an inhibitor of 3-hydroxy-2-methyl-glutaryl coenzyme A reductase. Lately, it has shown to have anti-inflammatory and bone stimulatory effects.
- Trial name
- NCT02386033
- Testing
- Atorvastatin (ATV)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Metabolic Syndrome
COMETS - Compare the Efficacy of Rosuvastatin With Atorvastatin and Placebo in the Treatment of Non-Diabetic, Non-Atheroscleric, Metabolic Syndrome Subjects
The purpose of this study is to compare the efficacy of treatment with rosuvastatin with atorvastatin in reducing Low density lipoprotein cholesterol over 6 weeks of treatment in subjects with metabolic syndrome.
- Trial name
- NCT00654485
- Testing
- Rosuvastatin, Atorvastatin
- Volunteers
- 940 people
- Sponsor
- AstraZeneca
Diabetes Mellitus, Hypertension
Oxidative Stress Lowering Effect of Simvastatin and Atorvastatin.
Background: HMG-CoA reductase inhibitors (statins) are effective lipid-lowering agents and are known to reduce cardiovascular events.
- Trial name
- SOS (NCT00404599)
- Testing
- atrorvastatin 10mg, simvastatin 40mg
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Amsterdam UMC, location VUmc
Chronic Kidney Disease
A Clinical Study to Evaluate the Pharmacokinetics of Microdose Midazolam, Dabigatran, Pitavastatin, Atorvastatin and Rosuvastatin in Healthy Volunteers and Renal Impairment Patients
1. To explore the functional changes of P-gp, CYP3A4, OATP1B and BCRP in Chinese people with renal impairment; 2. To explore the effect of dialysis on the functional changes of P-gp, CYP3A4, OATP1B and BCRP in patients with…
- Trial name
- NCT05747768
- Testing
- Midazolam, dabigatran etexilate, pitavastatin, rosuvastatin and atorvastatin
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Chronic Subdural Hematoma
The Clinical Study of Atorvastatin and Dexamethasone on Treatment for Chronic Subdural Hematoma in the Patients With Coagulation Disorders
To evaluate Efficacy and Safety of oral Atorvastatin and Dexamethasone on conservative treatment for Chronic Subdural Hematoma (CSDH) patients with Coagulation Disorders
- Trial name
- NCT02192320
- Testing
- Atorvastatin, Atorvastatin and Dexamethasone
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Oriental Neurosurgery Evidence-Based-Study Team
HIV Infections, HIV Seronegativity
The Effect of Efavirenz and Nelfinavir on the Blood Levels of Certain Lipid-Lowering Drugs
The purpose of this study is to find out whether certain anti-HIV drugs (efavirenz [EFV] and nelfinavir [NFV]) affect the amount of certain fat-lowering drugs (atorvastatin, pravastatin, and simvastatin) in the blood.
- Conditions
- HIV Infections, HIV Seronegativity, Lipodystrophy
- Trial name
- NCT00017758
- Testing
- Pravastatin sodium, Simvastatin, Atorvastatin calcium
- Where
- 10 sites in United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy
Bioequivalence Study of Atorvastatin Calcium Tablets, 40 mg of Dr. Reddy's Under Fed Conditions
The purpose of this study is to assess the bioequivalence between Atorvastatin calcium 40 mg of Dr. Reddy's Laboratories Limited, India and Lipitor® 40mg Tablets of Pfizer Ireland Pharmaceuticals in healthy, adult, human subjects…
- Trial name
- NCT01645410
- Testing
- Atorvastatin Calcium Tablets, 40 mg
- Where
- India
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Hypercholesterolemia
Efficacy and Safety Study of Pitavastatin Versus Atorvastatin to Treat Hypercholesterolemia
Statin is an effective drug to treat hyperlipidemia (hypercholesterolemia), and it rarely leads to hepatic damage to the patients with hepatic disorder. For these patients, intensive monitoring is required.
- Trial name
- PITCH (NCT01166633)
- Testing
- pitavastatin, atorvastatin
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- JW Pharmaceutical
Hyperlipidemia, Dyslipidemia
A Clinical Trial Comparing Torcetrapib/Atorvastatin To Simvastatin In Subjects With High Cholesterol (A5091031).
The Torcetrapib project was terminated on December 2, 2006 due to safety findings. Cholesterol levels will be measured over six weeks in subjects being treated with two different kinds of cholesterol medications to see how the…
- Conditions
- Hyperlipidemia, Dyslipidemia, Hypercholesterolemia
- Trial name
- NCT00267280
- Testing
- torcetrapib/atorvastatin, simvastatin
- Where
- 51 sites in United States
- Volunteers
- 640 people
- Sponsor
- Pfizer