Clinical trials: Atrial Fibrillation, Postoperative
Postoperative Atrial Fibrillation, Lung Surgery
Perioperative Statins to Prevent AFib After Lung Surgery
The goal of this clinical trial is to learn whether short-term treatment with atorvastatin can prevent new abnormal rapid heart rhythms after lung surgery in adults aged 60 years or older who are scheduled to have a lung segment…
- Trial name
- STAT-LUNG (NCT07727681)
- Testing
- Atorvastatin
- Where
- 2 sites in China
- Volunteers
- 540 people
- Sponsor
- Peking Union Medical College Hospital
Atrial Fibrillation
ALDOsterone for Prediction of Post-Operative Atrial Fibrillation
Post-operative atrial fibrillation (POAF) is a major and frequent complication occurring after cardiac surgery, contributing to prolonged intensive care and hospital stays and is associated with several cardiovascular…
- Trial name
- ALDO-POAF (NCT02814903)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Caen
Post Operative Atrial Fibrillation
Prevention of Post-OP AFib Using Combination of CardiaMend and Amiodarone
The purpose of this study is to evaluate the combination of CardiaMend, with the addition of amiodarone in the prevention of postoperative atrial fibrillation (POAF) in patients undergoing isolated cardiac arterial bypass…
- Trial name
- CAMP POAF (NCT05681182)
- Testing
- CardiaMend with the Addition of Amiodarone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- WakeMed Health and Hospitals
Atrial Fibrillation
Vitamin C for Prophylaxis of Post-operative Atrial Fibrillation in On-pump Cardiac Surgery Procedures
The purpose of this study is to determine whether vitamin C is effective in the prophylaxis of post-operative atrial fibrillation in on-pump cardiac surgery
- Trial name
- NCT01107730
- Testing
- Vitamin C, L-Carnitine
- Where
- Greece
- Volunteers
- 33 people
- Sponsor
- Attikon Hospital
Systemic Inflammatory Response Syndrome
INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery
The aim of the study is to evaluate a clinically and economically most effective diagnostic algorithm for prediction of inflammatory response related complications in patients undergoing heart surgery with use of cardiopulmonary…
- Trial name
- INFLACOR (NCT01020409)
- Testing
- cardiac surgery with CPB use
- Where
- Poland
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Mitral Regurgitation, Computed Tomography
Atrial Fibrillation Risk After Miniinvasive Mitral Valve Repair
This retrospective cohort study investigates how CT-derived tissue quality parameters, serving as markers of metabolic status, predict post-operative atrial fibrillation risk in patients undergoing minimally invasive mitral valve…
- Conditions
- Mitral Regurgitation, Computed Tomography, Atrial Fibrillation
- Trial name
- NCT06707506
- Volunteers
- 114 people
- Sponsor
- Nemocnice AGEL Trinec-Podlesi a.s.
Arrhythmias, Cardiac, Cardiovascular Diseases
Randomized Clinical Trial PULVAB (Prophylactic Pulmonary Veins Ablation)
To compare prophylactic strategies of atrial fibrillation in patients with CAD and without AF.
- Conditions
- Arrhythmias, Cardiac, Cardiovascular Diseases, Postoperative Atrial Fibrillation, Myocardial Ischemia
- Trial name
- PULVAB (NCT03857711)
- Testing
- Conventional CABG, CABG+ PVI, CABG+ PVI+amiodarone
- Where
- 2 sites in Russia
- Volunteers
- 280 people
- Sponsor
- National Research Center of Surgery, Russia
Atrial Fibrillation New Onset
A Pharmaco-surgical Approach to Reduce Postoperative Atrial Fibrillation After Cardiac Surgery
Postoperative atrial fibrillation (POAF) is a common complication following cardiac surgery with an estimated incidence around 35%.
- Trial name
- NCT05780320
- Testing
- Prophylactic amiodarone and posterior pericardiotomy
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- Massachusetts General Hospital
Atrial Fibrillation, Restore of Sinus Rhythm
AMAZING PRAGUE (PRAGUE-12)
Aim of the project is to assess the long-time clinical impact of surgical ablation (MAZE procedure) on patients who suffer from atrial fibrillation but are indicated to a cardiac surgery for other predominant cardiac diagnosis…
- Conditions
- Atrial Fibrillation, Restore of Sinus Rhythm, Post-Operative Complications
- Trial name
- AmP (NCT00665587)
- Testing
- Cox-MAZE III
- Where
- 3 sites in Czechia
- Volunteers
- 220 people
- Sponsor
- Charles University, Czech Republic
Arrhythmia
Does Atorvastatin Prevent Post Operative Atrial Fibrillation After Pulmonary Resection: A Randomized Clinical Study
The purpose of this study is to determine if atorvastatin (Lipitor) reduces the occurence of abnormal heart rhythm (atrial arrhythmia) following non cardiac thoracic surgery.
- Trial name
- NCT00756886
- Testing
- Atorvastatin
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Atrial Fibrillation, Left Ventricular Diastolic Dysfunction
Characterizing Patients With POAF in Relation to Cardiac Surgery by wavECG and TTE
Post-operative atrial fibrillation (POAF) is frequently observed after open-heart surgery. Despite numerous attempts to predict POAF, it remains a challenge to correctly identify the patients at risk.
- Trial name
- NCT03962166
- Where
- Denmark
- Volunteers
- 353 people
- Sponsor
- Helena DOMINGUEZ
Esophagectomy, Pneumonectomy
Stellate Ganglion Block
The purpose of this study is to determine if the addition of an ultrasound guided left sided stellate ganglion block with bupivacaine in patients undergoing esophagectomy, pneumonectomy, or lobectomy will result in lower rates of…
- Conditions
- Esophagectomy, Pneumonectomy, Lobectomy
- Trial name
- NCT06271707
- Testing
- 0.5% bupivacaine, Saline
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Minnesota
Cardiac Surgery
Prevention Atrial Fibrillation by BOTulinum Toxin Injections (BOTAF)
Over the past few years, research has focused on the prevention of atrial fibrillation (AF) after cardiac surgery, but highly effective interventions are still missing.
- Trial name
- BOTAF (NCT04075981)
- Testing
- Botulinum Toxin Type A Injection [Xeomin]
- Where
- 7 sites in France
- Volunteers
- 220 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Postoperative Atrial Fibrillation
Prevention of Postoperative Atrial Fibrillation
The primary aim of this study is to determine the safest and most effective therapeutic strategy to decrease the incidence of postoperative atrial fibrillation following cardiac surgery in an era with shorter ICU and hospital…
- Trial name
- NCT01742039
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- George Washington University
POAF, Atrial Fibrillation
CardiaMend and Amiodarone for the Prevention of POAF
The principal purpose of this investigator-initiated trial is to study the use of the CardiaMend device soaked in the anti-arrhythmic drug amiodarone, and how it may decrease the development of atrial fibrillation in patients…
- Trial name
- NCT05641883
- Testing
- CardiaMend with antiarrhythmic
- Volunteers
- 30 people
- Sponsor
- Saint Alphonsus Regional Medical Center
Atrial Fibrillation, Atrial Arrhythmia
Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
The study aims to evaluate and compare the incidence of atrial arrhythmias (including Post-Operative Atrial Fibrillation (POAF), atrial flutter, and atrial tachycardia) stratified by baseline Utah fibrosis stages and overall…
- Conditions
- Atrial Fibrillation, Atrial Arrhythmia, Atrial Flutter, Atrial Tachycardia
- Trial name
- NCT05014802
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Tulane University
Vagus Nerve Stimulation, Acute Coronary Syndrome
Auricular Vagus Stimulation and STEMI
At the moment, the invasive strategy for the infarct-associated coronary artery in patients with ST-segment elevation myocardial infarction (STEMI) necessary to save the myocardium and reduce the size of the necrosis zone remains…
- Conditions
- Vagus Nerve Stimulation, Acute Coronary Syndrome, Ischemia Reperfusion Injury
- Trial name
- NCT05992259
- Testing
- TENS
- Where
- Russia
- Volunteers
- 110 people
- Sponsor
- Bakulev Scientific Center of Cardiovascular Surgery
Post Operative Arrythmia, Anesthesia
Corticosteroids Prevent the Atrial Fibrillation After Cardiac Surgery
Cardiopulmonary bypass and cardiac surgery are associated with a significant systemic inflammatory response that has been suggested playing a causative role in the development of postoperative atrial fibrillation (POAF).
- Conditions
- Post Operative Arrythmia, Anesthesia, Cardiac Surgery, Corticosteroids
- Trial name
- NCT06802432
- Testing
- 1 g of methylprednisolone (divided into 250 mg every 6h started once the patient arrived the pos-toparative ICU)
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Ain Shams University
Atrial Fibrillation New Onset
Evaluation Of New Onset Postoperative Atrial Fibrillation
This is a multi-center, prospective, randomized and controlled clinical trial comparing the safety and efficacy of the CorMatrix ECM for Pericardial Closure to reduce the incidence of new onset postoperative atrial fibrillation…
- Trial name
- NCT01247974
- Testing
- CorMatrix ECM for Pericardial Closure
- Where
- 16 sites in United States
- Volunteers
- 439 people
- Sponsor
- Elutia Inc.
Atrial Fibrillation
Prophylaxis for Patients at Risk to Eliminate Post-operative Atrial Fibrillation
After surgery on the lungs or esophagus, 12-46% of patients experience an irregular heart rhythm called atrial fibrillation. Although usually transient, post-operative atrial fibrillation is associated with longer stay in…
- Trial name
- PREP-AF (NCT04392921)
- Testing
- Amiodarone
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Ottawa Hospital Research Institute