Clinical trials: Atrial Fibrillation Catheter Ablation
Atrial Fibrillation, Heart Failure With Preserved Ejection Fraction
CASTLE-HFpEF (Catheter Ablation for Atrial Fibrillation Patients With Heart Failure With Mildly Reduced and Preserved Ejection Fraction)
The clinical equipoise in the treatment of Atrial Fibrillation (AF) in patients with Heart Failure with mildly reduced Ejection Fraction/Heart Failure with Preserved Ejection Fraction (HFmrEF/HFpEF) reflects the scarcity of…
- Trial name
- NCT07254455
- Testing
- Catheter ablation
- Volunteers
- 900 people
- Sponsor
- Tulane University
Atrial Fibrillation, Atrial Flutter
Feasibility Study on the VERAFEYE Imaging and Navigation System for Guided Catheter Ablation Procedures
The objective of the study is to collect data on the usability and integration of the VERAFEYE Imaging and Guidance System in adult patients indicated to undergo a standard of care catheter-based ablation procedure for the…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Atrial Arrhythmia
- Trial name
- INSiGHT (NCT07271238)
- Testing
- VERAFEYE Imaging and Guidance System
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- LUMA Vision Ltd.
Paroxysmal Atrial Fibrillation
Comparison of Single Groin and Single Trans-septal Puncture and Conventional Bilateral Groin Puncture and Double Trans-septal Puncture in Catheter Ablation for Atrial Fibrillation
The purpose of this study is to compare single groin puncture and bilateral groin puncture during AF ablation procedure. The investigators will compare 1) the degree of patients' discomfort during hemostasis by questionaire, 2)…
- Trial name
- NCT02438176
- Testing
- single trans-septal puncture, conventional bilateral groin puncture
- Where
- South Korea
- Volunteers
- 105 people
- Sponsor
- Yonsei University
Paroxysmal Atrial Fibrillation
3-Dimensional Mapping System: The PULSTAR Study
The purpose of this study is to verify the safety and efficacy of the cardiac pulse ablation system in paroxysmal atrial fibrillation to provide the basis for product registration and clinical application.
- Trial name
- NCT05618340
- Testing
- Pulsed electric field ablation device;Cardiac Pulsed Electric Field Ablation Catheter
- Where
- China
- Volunteers
- 149 people
- Sponsor
- Shanghai Shangyang Medical Technology Co., Ltd.
Atrial Fibrillation, Heart Failure
The Impact of Atrial Pressure Change Before and After Combined Procedure
One-stop procedure combining catheter ablation (CA) and left atrial appendage closure (LAAC) has been a feasible treatment for patients with atrial fibrillation at high risk of stroke and/or bleeding.
- Trial name
- NCT05106270
- Testing
- Atrial pressure measurement using transseptal puncture sheath
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai 10th People's Hospital
Atrial Fibrillation
Examination of Fibrillation Atria Using Magnetic Resonance Imaging and Endocardial High-density Mapping
Cather ablation of non-paroxysmal atrial fibrillation is less effective compared to paroxysmal atrial fibrillation. Therefore, new techniques have been developed, such as high-density mapping to determine areas of focal and…
- Trial name
- NCT05539313
- Testing
- High-density mapping
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- Charles University, Czech Republic
Atrial Fibrillation
Radiofrequency Balloon Ablation for Atrial Fibrillation: Durability of Pulmonary Vein Isolated and Clinical Outome
Atrial fibrillation (AF) is the most common heart rhythm disorder affecting 2-4% of the adult human population. AF is a disturbance in the electrical impulses of the heart - an electrical disturbance commonly originating from the…
- Trial name
- RABAAF (NCT06296888)
- Testing
- Radiofrequency balloon catheter ablation
- Where
- Denmark
- Volunteers
- 45 people
- Sponsor
- Jim Hansen
Atrial Fibrillation (AF), Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF)
An AI-ECG-Based Approach for Dynamic Assessment of Heart Failure Risk and Myocardial Recovery Following Atrial Fibrillation Ablation
Background Artificial intelligence-enabled electrocardiography (AI-ECG) has emerged as a promising digital biomarker for detecting latent myocardial dysfunction and predicting cardiovascular risk.
- Trial name
- NCT07708818
- Where
- South Korea
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University Mokdong Hospital
Atrial Tachycardia, Atrial Fibrillation
Catheter Ablation of All Inducible AT Post AF Ablation
In the treatment of symptomatic drug resistant persistent atrial fibrillation (Ps AF), catheter ablation has a class IIA indication.
- Trial name
- INDUCATH (NCT03343860)
- Testing
- AT case 1.1, AT case 2.1, AT case 1.2
- Where
- 6 sites in Belgium, France and 2 more
- Volunteers
- 60 people
- Sponsor
- AZ Sint-Jan AV
Atrial Fibrillation, Catheter Ablation
Esophageal Damage Protection During Pulmonary Vein Ablation. Pilot Study.
Catheter ablation of atrial fibrillation with electrical isolation of the pulmonary veins in the left atrium carries risk of esophagus thermal lesion. EnsoETM is a device .
- Conditions
- Atrial Fibrillation, Catheter Ablation, Esophageal Fistula, Esophageal Diseases
- Trial name
- NCT03832959
- Testing
- EnsoETM
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Atrial Fibrillation
Video-Assisted Thoracoscopic Pulmonary Vein Isolation Versus Percutaneous Catheter Ablation in Atrial Fibrillation Trial
Recent studies demonstrated that radiofrequency isolation of the pulmonary veins (PVI) and surgically video assisted thorascopic pulmonary vein isolation (VATS-PVI) are acceptable or even superior alternatives to antiarrhythmic…
- Trial name
- VATCAT (NCT01319747)
- Testing
- PVI, VATS-PVI
- Where
- Netherlands
- Volunteers
- 77 people
- Sponsor
- Medisch Spectrum Twente
Atrial Fibrillation (AF)
High Power Short Duration Radiofrequency Ablation of Atrial Fibrillation Using the QDOT MICRO™ Catheter
Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide, characterized by rapid and disorganized atrial activation leading to an irregular heart rhythm.
- Trial name
- Q-POWER (NCT06846502)
- Testing
- Pulmonary vein isolation
- Where
- Netherlands
- Volunteers
- 42 people
- Sponsor
- Amsterdam UMC, location VUmc
Atrial Fibrillation
Relationship Between Fibroblast Growth Factor 23 and Recurrence of Atrial Fibrillation After Catheter Ablation
To investigate whether fibroblast growth factor 23 can be used to predict recurrence after catheter ablation for atrial fibrillation and to provide an objective basis for the clinical selection of the optimal patients for…
- Trial name
- REBECCA (NCT02958839)
- Testing
- Catheter ablation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Atrial Fibrillation
Kansai Plus Atrial Fibrillation Trial
This is a 2x2 factorial randomized controlled trial (KPAF Trial), evaluating two different pharmacological approaches to improve long-term outcome of catheter ablation for atrial fibrillation (AF).
- Trial name
- KPAF (NCT01477983)
- Testing
- ATP guide additional ablation., Antiarrhythmic drug (AAD), Control
- Where
- Japan
- Volunteers
- 2,113 people
- Sponsor
- Kyoto University, Graduate School of Medicine
Atrial Fibrillation
AMIOdarone vs. Catheter Ablation for Prevention of Recurrent Symptomatic Atrial Fibrillation
Randomized trial of low-dose amiodarone therapy versus catheter ablation (CA) in older patients with persistent atrial fibrillation (AF).
- Trial name
- AmioCAAF (NCT02341105)
- Testing
- Catheter ablation, Amiodarone
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Population Health Research Institute
Atrial Fibrillation
General Anesthesia With ETT vs LMA in Patients Undergoing Ablation for Atrial Fibrillation
In recent years it has been shown that catheter ablation of symptomatic atrial fibrillation (PAF) is superior to antiarrhythmic drug therapy with regards to effectiveness and clinical outcomes.
- Trial name
- NCT02896595
- Testing
- General Anesthesia with endotracheal tube, General Anesthesia with laryngeal mask airway
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Virginia Commonwealth University
Persistent Atrial Fibrillation
A Dual Energy Catheter (PFA and RFA) and a PFA Catheter for the Treatment of PeAF
The goal of this clinical trial is to treatment of patients with persistent atrial fibrillation with PFA/RFA. 10 patients will be treated by PFA/RFA catheter or PFA catheter only.
- Trial name
- PFA，RFA，PeAF (NCT06232798)
- Testing
- a dual energy catheter (RF and PFA) or PFA catheter only will be to treat PeAF,Cardiac Pulsed Electric Field Ablation Catheter, catheter ablation
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Shanghai MicroPort EP MedTech Co., Ltd.
Ventricular Arrhythmias, Persistent Atrial Fibrillation
Multimodal Image Processing Software to Guide Cardiac Ablation Therapy
MIGAT will develop and transfer software tools to assist ablation therapy of cardiac arrhythmias. The scientific background and objectives of MIGAT differ between atrial and ventricular arrhythmias, because the knowledge on…
- Trial name
- MIGAT (NCT02275104)
- Testing
- Contrast-enhanced ECG-gated multi-detector computed tomography, Magnetic resonance imaging, Positron emission tomography
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Bordeaux
Atrial Fibrillation
Does Cardiac Rehabilitation Reduce the Risk of Recurrence of Atrial Fibrillation Following the First Catheter Ablation?
Many risk factors contribute to the onset of atrial fibrillation. This study is specifically concerned with the effect of addressing these risk factors by cardiac rehabilitation on the risk of recurrence of atrial fibrillation…
- Trial name
- NCT03389633
- Testing
- rehabilitation
- Volunteers
- 462 people
- Sponsor
- prof. dr. Paul Dendale
Atrial Fibrillation (AF), Catheter Ablation
PROMBot-HSM-FA: Protocol for a Feasibility Study of a Chatbot Platform to Collect Patient-reported Outcomes After AF Ablation
The goal of this clinical trial is to learn if using a WhatsApp-based chatbot called PROMBot-FA can help people recover after atrial fibrillation ablation.
- Trial name
- PROMBot-HSM-FA (NCT07237178)
- Testing
- PROMBot-FA Chatbot-Supported Follow-Up, Standard Care (in control arm)
- Volunteers
- 76 people
- Sponsor
- Ana Rita Londral, PhD