Clinical trials: Atrial Fibrillation Catheter Ablation
Atrial Fibrillation, Catheter Ablation
Inflammatory Response Following " Pulsed Field Ablation " vs. Radiofrequency Ablation-2
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. Catheter ablation using pulmonary vein isolation (PVI) in an established treatment strategy for AF.
- Conditions
- Atrial Fibrillation, Catheter Ablation, Inflammation
- Trial name
- RIPAF-2 (NCT06160076)
- Testing
- Radiofrequency, Pulsed electric field
- Where
- France
- Volunteers
- 63 people
- Sponsor
- University Hospital, Bordeaux
Catheter-based Ablation of Atrial Fibrillation
Swiss Atrial Fibrillation Pulmonary Vein Isolation Registry
Registry of patients with atrial fibrillation undergoing catheter-based ablation of atrial fibrillation (pulmonary vein isolation) to determine long-term success rates of catheter-based ablation of atrial fibrillation (pulmonary…
- Trial name
- SWISS-AF-PVI) (NCT03718364)
- Testing
- catheter-based ablation of atrial fibrillation (pulmonary vein isolation)
- Where
- 2 sites in Switzerland
- Volunteers
- 3,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Persistent Atrial Fibrillation, Radiofrequency Catheter Ablation
Pulsed Field Ablation Versus Radiofrequency Ablation for Persistent Atrial Fibrillation
This clinical trial aims to compare the efficacy and safety of pulsed field ablation and radiofrequency ablation to treat persistent atrial fibrillation in adults.
- Conditions
- Persistent Atrial Fibrillation, Radiofrequency Catheter Ablation, Pulsed Field Ablation
- Trial name
- PRAISE (NCT06791629)
- Testing
- Pulsed Field Ablation, Radiofrequency Ablation
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Beijing Anzhen Hospital
Persistent Atrial Fibrillation, Catheter Ablation
Persistent Atrial Fibrillation Without the Evidence of Low-voltage Areas
An effective therapy of persistent atrial fibrillation beyond pulmonary vein isolation remains unsatisfactory. Targeting endocardial low-voltage areas represents an approach of substrate modification.
- Conditions
- Persistent Atrial Fibrillation, Catheter Ablation, Low Voltage Areas
- Trial name
- NCT06124690
- Testing
- Catheter ablation
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Robert Bosch Medical Center
Atrial Fibrillation, Catheter Ablation
Post-Ablation Pericarditis Reduction Study (PAPERS)
There has not been a prospective, randomized controlled trial of colchicine to reduce post-AF ablation pericarditis in an era of newer AF ablation techniques.
- Conditions
- Atrial Fibrillation, Catheter Ablation, Pericarditis
- Trial name
- PAPERS (NCT06731595)
- Testing
- Colchicine
- Where
- United States
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- St. Vincent Cardiovascular Research Institute
Atrial Fibrillation, Atrio-Oesophageal Fistula
PrOgnosis Following Esophageal FisTula FormaTion in Pts Undergoing CathetER Ablation for AF Study
Pulmonary vein isolation emerged as an effective and safe strategy to treat atrial fibrillation patients. Atrio-oesophageal fistula (AOF) represents a rare but devastating complication of AF ablation procedure.
- Conditions
- Atrial Fibrillation, Atrio-Oesophageal Fistula, PVI, Catheter Ablation
- Trial name
- POTTER (NCT05273645)
- Where
- Germany
- Volunteers
- 138 people
- Sponsor
- University of Luebeck
Persistent Atrial Fibrillation, Catheter Ablation
Comparison Between Upgraded '2C3L' vs. PVI Approach for Catheter Ablation of Persistent Atrial Fibrillation
Catheter ablation has emerged as an important treatment option for patients with symptomatic atrial fibrillation (AF). Pulmonary vein antral isolation (PVI) is now considered the cornerstone technique of AF ablation and has shown…
- Trial name
- PROMPT-AF (NCT04497376)
- Testing
- upgraded '2C3L', pulmonary vein antral isolation
- Where
- 12 sites in China
- Volunteers
- 498 people
- Sponsor
- Beijing Anzhen Hospital
Persistent Atrial Fibrillation, Catheter Ablation
Left Atrial Posterior Wall Additional Isolation for Persistent Atrial Fibrillation Trial
The purpose for this study is to determine whether left posterior wall isolation (PWI) in addition to pulmonary vein isolation (PVI) is effective as ablation strategy for persistent atrial fibrillation (AF).
- Conditions
- Persistent Atrial Fibrillation, Catheter Ablation, Pulmonary Vein Isolation, Posterior Wall Isolation
- Trial name
- LEAP-AF (NCT04405258)
- Testing
- Pulmonary vein isolation, Left posterior wall isolation
- Where
- Japan
- Volunteers
- 276 people
- Sponsor
- Institute for Clinical Effectiveness, Japan
Atrial Fibrillation, Catheter Ablation
AF Ablation With High Power Short Duration RF
This is a prospective, multi-center, research study designed to evaluate the safety and efficacy of pulmonary vein (PV) isolation with high power short duration radiofrequency energy in patients with paroxysmal/persistent atrial…
- Trial name
- AIR HPSD (NCT05777551)
- Where
- 9 sites in France, Italy and 1 more
- Volunteers
- 850 people
- Sponsor
- Clinica Mediterranea
Atrial Fibrillation, Catheter Ablation
High Radiofrequency Power for Faster and Safer Pulmonary Vein Ablation Trial (POWER FAST III)
Multicenter 1:1 randomized study. Two atrial fibrillation ablation strategies are compared: 1) conventional ablation using point-by-point radiofrequency applications with power 40 W guided by LSI > 6 or AI > 500 on the anterior…
- Trial name
- POWER-FAST (NCT04153747)
- Testing
- High-power and short-duration radiofrequency ablatio (70 W / 9-10 s), Low-power (25-40 W) radiofrequency ablation guided by lesion size index (LSI) and ablation index (AI) values, Esophageal endoscopy
- Where
- Spain
- Volunteers
- 304 people
- Sponsor
- Hospital Universitario La Paz
Atrial Fibrillation, Persistent, Ganglionated Plexi
Ganglion Plexus Ablation in Persistent Atrial Fibrillation
This study aims to investigate the long-term efficacy and safety of incorporating ganglionated plexus ablation into radiofrequency ablation strategies for persistent atrial fibrillation.
- Conditions
- Atrial Fibrillation, Persistent, Ganglionated Plexi, Catheter Ablation
- Trial name
- NCT06181578
- Testing
- ganglionated plexus ablation
- Volunteers
- 50 people
- Sponsor
- Ning Zhou
Atrial Fibrillation Recurrent, Catheter Ablation
Effect of Dapagliflozin on the Recurrence of Atrial Tachyarrhythmia in Patients Undergoing Catheter Ablation of Atrial Fibrillation
The goal of this clinical trial is to test the effect of Dapagliflozin on the Recurrence of Atrial Tachyarrhythmia in Patients Undergoing Catheter Ablation of Atrial Fibrillation.
- Trial name
- NCT06111443
- Testing
- Dapagliflozin 10 mg [Farxiga]
- Where
- Taiwan
- Volunteers
- 196 people
- Sponsor
- Chang Gung Memorial Hospital
BTKi-induced Atrial Fibrillation, Hematologic Malignancy
IRAF-ABLATION Study: a Multicenter International Retrospective Cohort of Patients With BTK Inhibitors-related AF Treated by Catheter Ablation
Targeted anticancer drugs have completely changed the prognosis of malignancies during the past decades. Patients suffering from malignancies live longer and this allows adverse events of anticancer drugs to emerge, notably…
- Conditions
- BTKi-induced Atrial Fibrillation, Hematologic Malignancy, Atrial Fibrillation Catheter Ablation
- Trial name
- NCT06130709
- Testing
- Atrial fibrillation catheter ablation in a population of BTKi-induced atrial fibrillation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Caen
Catheter Ablation, Rate Control
Catheter Ablation and Rate Control of Atrial Fibrillation in Patients With Heart Failure
To evaluate the efficacy of catheter ablation and rate control in heart failure patients with atrial fibrillation.
- Conditions
- Catheter Ablation, Rate Control, Heart Failure, Atrial Fibrillation
- Trial name
- NCT02846922
- Where
- China
- Volunteers
- 394 people
- Sponsor
- Nanjing Medical University
Patients With Atrial Fibrillation Undergoing Catheter Ablation
Comparison of Patients' Satisfaction Between Dexmedetomidine and Remimazolam Anesthesia in Patients With Atrial Fibrillation Undergoing Catheter Ablation
The primary purpose of this study was to investigate whether remimazolam administration for sedation had a positive effect on patients' satisfaction compared to dexmedetomidine administration in patients with atrial fibrillation…
- Trial name
- NCT05864404
- Testing
- remimazolam-remifentanil, dexmedetomidine-remifentanil
- Where
- South Korea
- Volunteers
- 142 people
- Sponsor
- Yonsei University
Atrial Fibrillation, Catheter Ablation
Prognostic Factors for Ablation of Atrial Fibrillation
The aim of the study is to find factors associated with sinus rhythm maintenance after catheter ablation for atrial fibrillation.
- Conditions
- Atrial Fibrillation, Catheter Ablation, Spectral Analysis, Vectorcardiography
- Trial name
- NCT05716581
- Testing
- Catheter ablation
- Volunteers
- 300 people
- Sponsor
- Charles University, Czech Republic
Atrial Fibrillation Patients With Moderate or High Stroke Risk Who Had Undergone Catheter Ablation of Atrial Fibrillation
AnticoaguLation ONE Year After Ablation of Atrial Fibrillation in Patients With Atrial Fibrillation (ALONE AF Study)
There has no evidence for the anticoagulation in patients who had undergone catheter ablation of atrial fibrillation, and has maintained sinus rhythm for more than 1 year.
- Trial name
- NCT04432220
- Testing
- Anticoagulation group(Apixaban group)
- Where
- South Korea
- Volunteers
- 840 people
- Sponsor
- Yonsei University
Atrial Fibrillation, Catheter Ablation
Post-Ablation Pericarditis Reduction Study
There has not been a prospective, randomized controlled trial of colchicine to reduce post-AF ablation pericarditis in an era of newer AF ablation techniques.
- Conditions
- Atrial Fibrillation, Catheter Ablation, Pericarditis
- Trial name
- PAPERS (NCT04906720)
- Testing
- Colchicine
- Where
- United States
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- St. Vincent Cardiovascular Research Institute
Atrial Fibrillation, Catheter Ablation
Electroacupuncture Intervention in Catheter Ablation of Atrial Fibrillation
This is a randomized control trial to determine whether electroacupuncture(EA) intervention with Morphine can reduce the intraoperative pain and early post-operative complications in patients undergoing catheter ablation of…
- Trial name
- NCT05575544
- Testing
- Acupuncture plus morphine
- Volunteers
- 200 people
- Sponsor
- Shanghai Chest Hospital
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Combined Study of ATrial Strain and Voltage by High Density Mapping in Young Patients With Atrial Fibrillation.
Atrial The treatment of atrial fibrillation (AF) includes 2 axes: the prevention of the cardio-embolic risk and rhythm control. The possibilities for this control are antiarrhythmic drugs and, above all, catheter ablation, an…
- Conditions
- Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation, Catheter Ablation, Atrial Cardiomyopathy
- Trial name
- CATS-AF (NCT05565183)
- Testing
- MRI (with injection of contrast product)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris