Clinical trials: Atrial Fibrillation Mechanisms
Deep Venous Thrombosis, Pulmonary Embolism
Drug Interaction Between Paracetamol and Warfarin
The objective of this study is to investigate whether paracetamol, given at therapeutic doses (2g/day and 3 g/day), may potentiate the anticoagulant effect of warfarin.
- Conditions
- Deep Venous Thrombosis, Pulmonary Embolism, Atrial Fibrillation, Stroke
- Trial name
- INPAWA2 (NCT01104337)
- Testing
- paracetamol
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Hopital Lariboisière
Atrial Fibrillation, Obstructive Sleep Apnea
Mechanisms for Atrial Fibrillation in Obstructive Sleep Apnea
Atrial fibrillation (AF) is the most common rhythm disorder and involves an increased risk of cardiovascular disease and death, impaired quality of life and a high proportion of healthcare consumption.
- Conditions
- Atrial Fibrillation, Obstructive Sleep Apnea, Hypertension, Autonomic Dysfunction
- Trial name
- AF-MiTriSto (NCT06465134)
- Testing
- No intervention
- Where
- 3 sites in Italy, Sweden
- Volunteers
- 300 people
- Sponsor
- Danderyd Hospital
Atrial Fibrillation Mechanisms, Persistent Atrial Fibrillation
'Understanding the Electrophysiological Substrate Underlying Persistent Atrial Fibrillation Study II (USURP AF- Study II)'
Atrial fibrillation (AF) is the most common type of chronic heart rhythm disease worldwide, with significant associated co-morbidities.
- Conditions
- Atrial Fibrillation Mechanisms, Persistent Atrial Fibrillation, Substrate Ablation, Pulmonary Vein Isolation
- Trial name
- USURPAF (NCT04041778)
- Testing
- Catheter ablation
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University of Leicester
Atrial Fibrillation
Atrial Fibrillation Stratification Based on the Arrhythmia Perpetuation Mechanisms
Atrial fibrillation treatments have a limited efficacy and often cause long-term side effects. This study aims to develop and validate an ECGI system to risk stratification in patients with persistent AF, identifying the…
- Trial name
- NCT04578275
- Testing
- diagnostic strategy using ECGI
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Felipe Atienza
Atrial Fibrillation, Permanent Atrial Fibrillation
Rate Control in Atrial Fibrillation II
The RATAF II study is a randomized, prospective, parallel group study, designed to compare the effects of two different drug regimens for rate control in permanent AF (atrial fibrillation).
- Trial name
- RATAFII (NCT02695992)
- Testing
- Metoprolol, Diltiazem
- Where
- Norway
- Volunteers
- 122 people
- Sponsor
- Asker & Baerum Hospital
Atrial Fibrillation
Autoimmunity in the Pathogenesis of AF
This research study is being done to find out whether autoimmune mechanisms are associated with the development of atrial fibrillation.
- Trial name
- NCT03498729
- Testing
- Peripheral Blood Sample
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Persistent Atrial Fibrillation
Study on the Prevention of Atrial Fibrillation Recurrence After Ablation by Qidong Yixin Granule
The goal of this clinical trial is to investigate the efficacy and safety of Qidong Yixin Granules in preventing recurrence in patients after radiofrequency catheter ablation for atrial fibrillation.
- Trial name
- QDYX-AF (NCT07508618)
- Testing
- Qi Dong Yi Xin Granules
- Where
- 5 sites in China
- Volunteers
- 846 people
- Sponsor
- Sir Run Run Shaw Hospital
Atrial Fibrillation
Characterization and Elimination of Mother Rotors
Recent clinical studies have shown that atrial fibrillation (AF) in humans might be sustained by localized sources called "mother rotors" which exhibit persistent, fast, and well organized activity during AF and play an important…
- Trial name
- CENTRA-AF (NCT01924377)
- Testing
- standard circumferential pulmonary vein isolation by radiofrequency ablation catheter, CPVI + rotors' identification and ablation
- Where
- Italy
- Sponsor
- Maria Cecilia Hospital
Subarachnoid Hemorrhage, Aneurysmal, Cerebrocardiac Syndrome
Mechanisms of Brain-Heart Injury of Post-Intracranial Hemorrhage
Intracranial hemorrhage is a condition characterized by high mortality rates and suboptimal functional outcomes. It precipitates both direct brain injury and subsequent secondary injuries, including delayed cerebral ischemia…
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Cerebrocardiac Syndrome, Mass Spectrometry, Heart Failure
- Trial name
- NCT06906432
- Testing
- Multi-disciplinary assessment
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Atrial Fibrillation (AF)
Mechanisms of Myocardial Injury and Ischemia in Patients With Rapid Atrial Fibrillation
The goal of this observational study is to better understand the role of measuring troponin (a protein measured by a blood test) and coronary imaging in patients presenting with rapid atrial fibrillation (AF) The main questions…
- Trial name
- Mi-AF (NCT06951100)
- Testing
- CT coronary angiography
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- University of Edinburgh