Clinical trials: Atrial Fibrillation Recurrence
Atrial Fibrillation, Recurrence
Comparison of Effectiveness of Ranolazine Plus Metoprolol Combination vs. FlecainidE pluS Metoprolol Combination in ATrial Fibrillation Recurrences FOllowing PhaRmacological or Electrical CardioverSion of AtRial Fibrillation
Atrial fibrillation (AF) is the most common arrhythmia in clinical practice with a prevalence reaching 5% in patients older than 65 years and an incidence that increases progressively with age.1 According to the most recent…
- Trial name
- PRESERVE-SR (NCT03162120)
- Testing
- Ranolazine plus Metoprolol Combination, FlecainidE pluS Metoprolol Combination
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Atrial Fibrillation
The Evaluation for Prognostic Factors After Catheter Ablation of Atrial Fibrillation: Cohort Study
1. Purpose of the study 1) To explore clinical recurrence associated clinical factors including age, sex, clinical, electrophysiological, anatomical, imaging, and serologic characteristics.
- Trial name
- NCT02138695
- Where
- South Korea
- Volunteers
- 3,100 people
- Sponsor
- Yonsei University
Atrial Fibrillation, Catheter Ablation
Efficacy of Pulmonary Vein Isolation Alone in Patients With Persistent Atrial Fibrillation
This study examines non-inferiority of pulmonary vein isolation (PVI) for persistent atrial fibrillation (AF) to extensive ablation; and reveals the effect of the presence or origin of AF trigger on outcomes of catheter ablation.
- Conditions
- Atrial Fibrillation, Catheter Ablation, Recurrence
- Trial name
- EARNEST-PVI (NCT03514693)
- Testing
- PVI, PVI plus additional ablation
- Volunteers
- 512 people
- Sponsor
- Osaka Cardiovascular Conference
Atrial Fibrillation
Clinical Benefits of Additional Complex Fractionated Atrial Electrogram Targeted Catheter Ablation for Longstanding Persistent Atrial Fibrillation
1. Purpose of the study 1) To compare clinical outcome, procedure time, complication rate of persistent atrial fibrillation patients between conventional additional linear ablation and additional complex fractionated atrial…
- Trial name
- NCT02175043
- Testing
- atrial electrogram and liner ablation
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Yonsei University
Atrial Fibrillation, Recurrence
Ablation of Complex Fractionated Electrograms With or Without Additional Linear Lesions for Persistent Atrial Fibrillation
While there is a consensus to perform pulmonary vein isolation (PVI) as a cornerstone for paroxysmal and persistent atrial fibrillation (AF), different additional ablation approaches are used for substrate modification: linear…
- Trial name
- ADLINE (NCT02059369)
- Testing
- PVI+CFAE+DCC, PVI, CFAE, anterior and roof line, DCC
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Atrial Fibrillation, Recurrence
Left Atrial Geometry and Outcomes After Atrial Fibrillation Ablation
This is a Multicenter Observational 1-year retrospective cohort study evaluating the predictive value of the Left Atrial Sphericity on the recurrence rate of atrial fibrillation after pulmonary vein ablation procedure.
- Trial name
- LAGO-FA (NCT02373982)
- Where
- 9 sites in Spain
- Volunteers
- 417 people
- Sponsor
- Hospital Clinic of Barcelona
Atrial Fibrillation
Moxonidine for Prevention of Post-ablation AFib Recurrences
Hypothesis: Modulation of central nervous sympathetic activation by administration of moxonidine, a centrally acting medication which decreases the sympathetic nervous system activity, can lead to a decrease in atrial…
- Trial name
- NCT01791699
- Testing
- Moxonidine
- Where
- 3 sites in Greece
- Volunteers
- 150 people
- Sponsor
- Spyridon Deftereos
Persistent Atrial Fibrillation
Acupuncture in Persistent Atrial Fibrillation
The aim of this trial is to evaluate the effect of acupuncture on prevention of atrial fibrillation (AF) recurrence after electrical cardioversion (EC) for persistent AF patients resistant to the antiarrhythmic drugs (AADs).
- Trial name
- NCT02110537
- Testing
- Active Acupuncture, flecainide
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Kyunghee University Medical Center
Atrial Fibrillation, Atrial Flutter
Therapy of Atrial Flutter by Afib Ablation
Ablation of the cavotricuspid isthmus (CTI) in the right atrium is currently the therapy of choice for the treatment of typical atrial flutter (3,4). It is a curative approach and has a high success rate (5).
- Trial name
- TripleA (NCT02051621)
- Testing
- Antiarrhythmic drug, Cavo-tricuspid-isthmus-ablation, Pulmonary vein isolation
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Rostock
Observation of Outcome After Catheter Ablation of Atrial Fibrillation
A French Multi-centric Atrial Fibrillation Catheter Ablation Survey
Atrial fibrillation is the most frequent sustained arrhythmia. Catheter ablation is a procedure that is currently used for the treatment of symptomatic atrial fibrillation patients.
- Trial name
- FrenchAF (NCT01918670)
- Testing
- catheter ablation of atrial fibrillation
- Where
- France
- Sponsor
- Clinique Pasteur
Atrial Fibrillation, Recurrence
Stepwise Approach Versus Linear Ablation in Patients With Recurrence of Persistent Atrial Fibrillation
Catheter ablation of persistent atrial fibrillation (AF) remains a challenging procedure. Even in experienced centres, repeat interventions are necessary in up to 70 of patients to achieve sinus rhythm at a long-term follow-up.
- Trial name
- REDO-AF (NCT01229475)
- Testing
- Ablation with stepwise approach, Linear ablation
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Paroxysmal Atrial Fibrillation, Catheter Ablation
Contact Force Sensing and Pulmonary Vein Isolation
Introduction - Pulmonary vein isolation (PVI) is the cornerstone of paroxysmal atrial fibrillation (AF) ablation. Recurrences remain, however, not infrequent and are mainly due to PVs reconnection.
- Trial name
- NCT01630031
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinique Pasteur
Atrial Fibrillation
Candesartan in the Prevention of Relapsing Atrial Fibrillation
The purpose of this study is to test the hypothesis that treatment with the angiotensin II type 1 receptor antagonist candesartan may reduce the recurrence rate of atrial fibrillation after electrical cardioversion.
- Trial name
- NCT00130975
- Testing
- Candesartan
- Where
- 2 sites in Norway
- Volunteers
- 200 people
- Sponsor
- Asker & Baerum Hospital