Clinical trials: Atrial Fibrillation Recurrent
Transient Ischemic Attack, Stroke
Apixaban for Early Prevention of Recurrent Embolic Stroke and Hemorrhagic Transformation
The purpose of this study is to evaluate if Apixaban will decrease the complication of having another stroke for people who have atrial fibrillation if initiated earlier than standard of care.
- Conditions
- Transient Ischemic Attack, Stroke, Atrial Fibrillation
- Trial name
- AREST (NCT02283294)
- Testing
- Apixaban, Warfarin
- Where
- 5 sites in United States
- Volunteers
- 91 people
- Sponsor
- University of South Florida
Stroke, Acute Cerebrovascular Accident
Radiofrequency and Cryoablation of the Posterior Wall of the Left Atrium
Atrial fibrillation (AF) is the cause of 20% of strokes, and the risk of stroke in a person suffering from this arrhythmia increases by 5 times.
- Conditions
- Stroke, Acute Cerebrovascular Accident, Transient Ischemic Attack, Death
- Trial name
- NCT06253000
- Testing
- Cryoablation, Radiofrequency ablation
- Where
- Russia
- Volunteers
- 158 people
- Sponsor
- Bakulev Scientific Center of Cardiovascular Surgery
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
High-Density (HD) Wave Mapping in Subjects With Atrial Fibrillation as a Predictor of Recurrence After a Single Ablation Procedure Using a PVI-Only Strategy
The aim is to use the Advisor™ HD Grid Mapping Catheter, Sensor Enabled™ to characterize the atrial substrate and develop a model for predicting recurrence rates after a single procedure using a PVI only approach and a contact…
- Conditions
- Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation, Cardiac Arrhythmia
- Trial name
- WAVE-MAP AF (NCT03882021)
- Testing
- A specific electrophysiology mapping protocol is applicable with the GRID catheter.
- Where
- 15 sites in Austria, Czechia and 7 more
- Volunteers
- 300 people
- Sponsor
- Abbott Medical Devices
Atrial Fibrillation Ablation Using PENTARAY Catheter
Predictors of Atrial Fibrillation Recurrence After Ablation Using PENTARAY Catheter
CARTO represent a new way of 3D electroanaromic mapping for AF which has improved safety and success rate of AF ablation compared with other conventional methods of AF ablation as it provide accurate visualization of atrial…
- Trial name
- NCT05101980
- Volunteers
- 20 people
- Sponsor
- Assiut University
Observation of Outcome After Catheter Ablation of Atrial Fibrillation
A French Multi-centric Atrial Fibrillation Catheter Ablation Survey
Atrial fibrillation is the most frequent sustained arrhythmia. Catheter ablation is a procedure that is currently used for the treatment of symptomatic atrial fibrillation patients.
- Trial name
- FrenchAF (NCT01918670)
- Testing
- catheter ablation of atrial fibrillation
- Where
- France
- Sponsor
- Clinique Pasteur
Paroxysmal Atrial Fibrillation
Role of Eplerenone in Reducing Recurrence of Atrial Fibrillation in Patient With Structural Heart Disease
The aim of this study is to study synergistic effect of eplerenone as Selective aldosterone receptor antagonist with amiodarone compared with amiodarone only in reducing recurrence of atrial fibrillation in patient with…
- Trial name
- NCT06168994
- Testing
- Eplerenone
- Volunteers
- 100 people
- Sponsor
- Assiut University
Persistent Atrial Fibrillation
Withdrawal Versus Continuation of Amiodarone in Successfully Treated Patients With Persistent Atrial Fibrillation
Amiodarone is considered to be the most effective antiarrhythmic drug in the prevention of persistent atrial fibrillation. It can however cause many adverse events, both cardiac and non-cardiac.
- Trial name
- WISDOM (NCT00845780)
- Testing
- withdrawal or continuation of amiodarone therapy
- Where
- Netherlands
- Volunteers
- 37 people
- Sponsor
- University Medical Center Groningen
Atrial Fibrillation
Apple Watch-led Surveillance of AF Recurrence After Catheter Ablation
Atrial fibrillation (AF) is a heart rhythm disorder associated with debillitating symptoms, psychological distress and heart failure. It can also significantly increase an individuals stroke risk.
- Trial name
- AFFU-AW (NCT05016791)
- Testing
- Apple Watch-based heart rhythm monitoring
- Where
- United Kingdom
- Volunteers
- 172 people
- Sponsor
- Barts & The London NHS Trust
Atrial Fibrillation Recurrent
Redo AF Sub Study (of the Pure EP 2.0 Main Study)
This study is a sub study of the Pure EP 2.0 trial. In a redo atrial fibrillation population, this study is designed to collect pulmonary vein signals pre and post ablation therapy, along with other non-pulmonary vein signals of…
- Trial name
- NCT04964440
- Testing
- Pure-EP
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- BioSig Technologies, Inc.
Atrial Fibrillation, Subclinical Hyperthyroidism
Is a Low Thyreotropin Level Predictive of Recurrent Arrhythmia After Catheter Ablative Surgery?
Overt hyperthyroidism (so-called "goiter" in lay language) is a hormonal disturbance that is known to increase the risk of atrial fibrillation (a common heart arrhythmia with potentially severe consequences) in some patients.
- Trial name
- TABLAS (NCT01789541)
- Where
- 2 sites in Sweden
- Volunteers
- 327 people
- Sponsor
- Karolinska Institutet
Atrial Fibrillation
Study of RSD1235-SR for the Prevention of Atrial Fibrillation/Atrial Flutter Recurrence
This study is designed to evaluate the safety, tolerability and preliminary efficacy of vernakalant (oral) in subjects with sustained atrial fibrillation of greater than 72 hours and less than 6 months duration
- Trial name
- NCT00267930
- Testing
- Vernakalant (oral)
- Where
- 22 sites in United States, Canada and 2 more
- Volunteers
- 221 people
- Sponsor
- Advanz Pharma
Atrial Fibrillation, Atrial Fibrillation Recurrent
DIGITal mOnitoring afTer Af abLation
Recurrence of atrial fibrillation (AF) after a pulmonary vein isolation (PVI) procedure is frequent. Current follow up with Holter monitoring and electrocardiograms (ECG) during outpatient clinic consultations cover only short…
- Conditions
- Atrial Fibrillation, Atrial Fibrillation Recurrent, PVI
- Trial name
- DIGITOTAL (NCT05486364)
- Testing
- Digital Monitoring, Standard of care
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Ziekenhuis Oost-Limburg
Ischemic Stroke, Paroxysmal Atrial Fibrillation
Paroxysmal Atrial Fibrillation in Patients With Acute Ischemic Stroke
The purpose of this study is to estimate the clinical relevance of monitoring patients with acute ischemic stroke with 48 hours' inpatient cardiac telemetry in relation to evaluate the presence of brief runs of premature atrial…
- Conditions
- Ischemic Stroke, Paroxysmal Atrial Fibrillation, Premature Atrial Complexes
- Trial name
- NCT02610803
- Where
- Denmark
- Volunteers
- 863 people
- Sponsor
- Odense University Hospital
Paroxysmal Atrial Fibrillation, Hypertension
Renal Denervation and pUlmonary Vein isolAtion With cryoabLation on Patients With Atrial Fibrillation and hypErtension
The DUAL-ICE study is a single-center, prospective, randomized controlled study. The main purpose is to verify that renal artery cryoablation combined with pulmonary vein cryoablation can reduce the recurrence of atrial…
- Trial name
- NCT05024630
- Testing
- Renal artery cryoablation, Pulmonary vein cryoablation, Renal arteriography
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai 10th People's Hospital
Atrial Fibrillation, Recurrence
Impact of Short-course Colchicine Versus Placebo After Pulmonary Vein Isolation (IMPROVE-PVI Pilot)
Recurrence is a common problem after catheter ablation for atrial fibrillation, affecting at least one out of three patients. Inflammation due to the procedure may contribute to pulmonary vein reconnection and, thus, failure of…
- Trial name
- NCT04160117
- Testing
- Colchicine 0.6 mg
- Where
- Canada
- Volunteers
- 202 people
- Sponsor
- Population Health Research Institute
Recurrent Paroxysmal Atrial Fibrillation Despite Prior Pulmonary Vein Isolation
Endocardial Vs Epicardial Ablation for Recurrent Paroxysmal AF
There is no current accepted and predictably effective ablative therapy for patients with recurrent paroxysmal atrial fibrillation after prior pulmonary vein isolation (PVI).
- Trial name
- REPEAL-AF (NCT04506814)
- Testing
- Endocardial PVI, Epicardial Posterior Wall Isolation + LAA Exclusion + Endocardial PVI
- Where
- United States
- Sponsor
- University of Rochester
Cryptogenic Stroke, Atrial Fibrillation
Incidence and Predictors of Recurrent Stroke in Cryptogenic Stroke Patients With Atrial Fibrillation
Brief Summary: This study aimed to investigate the risk and factors that predict recurrent stroke in patients who initially had a stroke with no clear cause (called cryptogenic stroke) and were later found to have atrial…
- Conditions
- Cryptogenic Stroke, Atrial Fibrillation, Recurrent Ischemic Stroke
- Trial name
- NCT07126184
- Testing
- Extended Cardiac Monitoring
- Where
- Pakistan
- Volunteers
- 109 people
- Sponsor
- Nangarhar University
Atrial Fibrillation
Prospective Cohort Study of the Risk of Recurrent Atrial Fibrillation After Radiofrequency Ablation
In this study, the continuous inclusion of atrial fibrillation patients treated by catheter ablation in the Department of Cardiology, Peking University Third Hospital, through the collection of clinical data and outpatient…
- Trial name
- NCT05638841
- Testing
- After radiofrequency ablation of atrial fibrillation
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University Third Hospital
Atrial Fibrillation
Evaluation of Predictive Factors for Recurrence of Persistent Atrial Fibrillation After Ablation
This is a single-center, retrospective, observational study based on data extracted from the medical records of patients who underwent a procedure for persistent atrial fibrillation ablation.
- Trial name
- FAIR (NCT06620575)
- Testing
- Atrial fibrillation ablation
- Where
- France
- Volunteers
- 542 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Fibrillation, Atrial
Evaluation of Efficacy and Safety of Lovaza (Omega-3-Acid Ethyl Esters) in Recurrent, Symptomatic Atrial Fibrillation
The purpose of this study is to evaluate efficacy and safety of Omacor (omega-3-acid ethyl esters) in patients with recurrent, symptomatic atrial fibrillation.
- Trial name
- NCT00402363
- Testing
- omega-3-acid ethyl esters
- Where
- 178 sites in United States
- Volunteers
- 663 people
- Sponsor
- GlaxoSmithKline