Clinical trials: Atrium; Flutter
Atrial Flutter, Ventricular Tachycardia
Clinical Study to Evaluate the Catheter Robotics Amigo for Performing Right-Sided Electrophysiology Mapping Studies
The purpose of this clinical study is to collect safety and performance data to support a demonstration of substantial equivalence of the Catheter Robotics Remote Catheter System to predicate devices when used to perform EP…
- Trial name
- NCT01139814
- Testing
- Amigo catheter robot
- Where
- 12 sites in United States, United Kingdom
- Volunteers
- 181 people
- Sponsor
- Catheter Robotics, Inc.
Atrial Fibrillation (AF)
Efficacy and Safety of Pulsed Field Ablation in Refractory Mitral Isthmus-dependent Atrial Flutter: Pulsed Field Ablation Vs. Radiofrequency Ablation: a Preliminary Randomized Controlled Study
Efficacy and safety of pulsed field ablation in refractory mitral isthmus-dependent atrial flutter: pulsed field ablation vs. radiofrequency ablation: a preliminary randomized controlled study
- Trial name
- NCT06850064
- Testing
- Pulse Field Ablation (PFA), Radiofrequency ablation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Chest Hospital
Atrial Fibrillation, Atrial Flutter
Atrial Fibrillation at the Viennese University Emergency Department
The results of this study could imply that a atrial fibrillation registry, as a tool for structured diagnosis and therapy in patients with atrial fibrillation, may improve patient care for this rapidly growing population.
- Trial name
- NCT03272620
- Where
- Austria
- Volunteers
- 3,000 people
- Sponsor
- Medical University of Vienna
Atrial Fibrillation
A Dose-range Finding Study of MAA868 in Patients With Atrial Fibrillation
This study is a multicenter, randomized, subject and Investigator-blinded, placebo-controlled, parallel-group, multiple ascending dose-ranging study to evaluate the safety, tolerability, pharmacokinetics (PK), and…
- Trial name
- NCT04213807
- Testing
- MAA868 Cohort 1, MAA868 Cohort 2, MAA868 Cohort 3
- Where
- 6 sites in United States
- Volunteers
- 28 people
- Sponsor
- Anthos Therapeutics, Inc.
Atrial Fibrillation, Arrhythmias, Cardiac
Apple Heart Study: Assessment of Wristwatch-Based Photoplethysmography to Identify Cardiac Arrhythmias
The Apple Heart Study (AHS) is a research study conducted to evaluate whether the Apple Heart Study App can use data collected on the Apple Watch to identify irregular heart rhythms, including those from potentially serious heart…
- Conditions
- Atrial Fibrillation, Arrhythmias, Cardiac, Atrial Flutter
- Trial name
- NCT03335800
- Testing
- Apple Heart Study App
- Where
- United States
- Volunteers
- 419,927 people, healthy volunteers welcome
- Sponsor
- Apple Inc.
Atrial Fibrillation, Atrial Tachycardia
Empiric Pulsed Field Pulmonary Vein Isolation During Atrial Tachycardia Ablation in Adults With Congenital Heart Disease
This is a prospective, single-arm intervention trial whereby we will test the safety and efficacy of performing pulmonary vein isolation (PVI) using pulsed field ablation (PFA) in adult patients with congenital heart disease…
- Conditions
- Atrial Fibrillation, Atrial Tachycardia, Atrial Flutter, Congenital Heart Disease
- Trial name
- NCT06969378
- Testing
- Pulsed field ablation using a pentaspline ablation catheter
- Sponsor
- Boston Children's Hospital
Anticoagulation, Atrial Fibrillation
AntiCoagulation Tracking InterVention and Evaluation
Anticoagulants are a leading cause of acute injury from adverse drug events, leading to ~20,000 serious injuries reported to the Food and Drug Administration per year and more than 220,000 emergency department visits annually.
- Conditions
- Anticoagulation, Atrial Fibrillation, Atrial Flutter, Pulmonary Embolus/Emboli
- Trial name
- ACTIVE (NCT04059965)
- Testing
- Panel Management for Anticoagulation Therapy, Usual Care
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Embolic Stroke of Undetermined Source, Ischemic Stroke
Biomarkers, Hemodynamic and Echocardiographic Predictors of Ischemic Strokes and Their Influence on the Course and Prognosis
A stroke is the second cause of deaths after heart attack, one of the most important causes of malfunction as far as adults are concerned and the second as for the frequency cause of dementia.
- Conditions
- Embolic Stroke of Undetermined Source, Ischemic Stroke, Atrial Fibrillation and Flutter, Myocardial Infarction
- Trial name
- NCT03377465
- Testing
- ADMA (asymmetric dimethylarginine) , NTproBNP (N-terminal pro b-type natriuretic peptide), IL-6 (Interleukin 6), Adiponectina, Leptine, Syndecan, Resistin
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Atrial Fibrillation and Flutter, Mechanical Mitral Valve Prosthesis
Impact of Education Level on Clinical Outcomes in Self-INR Managed Patients
Oral anticoagulation (OAC) is indicated in a wide variety of clinical conditions including atrial fibrillation (AF), mechanical valve prosthesis (MVP), deep vein thrombosis and pulmonary embolism.
- Trial name
- NCT06187155
- Testing
- INR self-management
- Where
- Egypt
- Volunteers
- 586 people
- Sponsor
- Cairo University
Atrial Flutter
The VERISMART Trial
Catheter ablation is now routinely used in the management of heart rhythm disorders. One of the problems with the approach is that it has not been possible to determine whether the ablation catheter is in direct contact with the…
- Trial name
- VERISMART (NCT02490033)
- Testing
- Ablation Catheter
- Where
- United Kingdom
- Volunteers
- 133 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Atrial Fibrillation and Flutter, Hyperthyroidism
Efficacy and Safety of Catheter Ablation of Atrial Fibrillation in Patients With Thyroid Hormone Stabilization
Patients with hyperthyroidism or hypothyroidism are often combined with atrial fibrillation, but after the stabilization of thyroid hormone levels after treatment, the patients' atrial fibrillation still persists.
- Conditions
- Atrial Fibrillation and Flutter, Hyperthyroidism, Hypothyroidism
- Trial name
- SQUIRREL (NCT06452823)
- Testing
- Catheter Ablation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Second Affiliated Hospital of Jiaxing University
Atrial Fibrillation, Atrial Flutter
Intravenous Tedisamil in the Rapid Conversion of Atrial Fibrillation or Flutter to Normal Sinus Rhythm in Female Subjects
The purpose of this study is to demonstrate the ability of tedisamil to convert atrial fibrillation or flutter into normal sinus rhythm (NSR) in female patients.
- Trial name
- NCT00126022
- Testing
- Tedisamil sesquifumarate
- Where
- 81 sites in United States, Argentina and 11 more
- Sponsor
- Solvay Pharmaceuticals
Intracranial Hemorrhages, Atrial Fibrillation (AF)
Comparison of LAA-Closure vs Oral Anticoagulation in Patients With NVAF and Status Post Intracranial Bleeding.
Atrial fibrillation is the most common cardiac arrhythmia. In atrial fibrillation, there is a risk that clots can form in the heart, especially in the left atrium. If these clots come loose, there is a risk of stroke.
- Conditions
- Intracranial Hemorrhages, Atrial Fibrillation (AF), Atrial Flutter
- Trial name
- CLEARANCE (NCT04298723)
- Testing
- Percutaneous closure of the LAA (Watchman / Watchman FLX)
- Where
- 39 sites in Germany, Poland
- Volunteers
- 530 people
- Sponsor
- Jena University Hospital
Death, Sudden, Cardiac, Ventricular Fibrillation
DISCOVERY: Diagnostic Data and Genetic Polymorphisms in ICD Patients.
To prospectively evaluate if the analysis of genetic polymorphisms can be used to identify patients at risk of ventricular tachycardia.
- Conditions
- Death, Sudden, Cardiac, Ventricular Fibrillation, Tachycardia, Atrial Fibrillation
- Trial name
- DISCOVERY (NCT00478933)
- Testing
- Defibrillator, Dual Chamber ; Implantable, Blood sampling
- Volunteers
- 1,223 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Atrial Fibrillation
Propagation ANalysis for Arrhythmogenic Conduction Elimination to Prevent Atrial Flutter and Fibrillation (PANACEA-AF)
The purpose of this study is to perform ultra-high density mapping of the left atrium (a chamber of the heart) using the the Rhythmia Mapping System and to determine whether additional ablation in areas of wavefront…
- Trial name
- PANACEA-AF (NCT03737838)
- Testing
- Atrial fibrillation ablation
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Chicago
Stroke, Venous Thrombosis
Clarification of Optimal Anticoagulation Through Genetics
Individuals taking warfarin often need frequent dose changes as the international normalized ratio (INR) gets too high or too low which could result in a higher risk of thromboembolism, bleeding and early discontinuation of a…
- Conditions
- Stroke, Venous Thrombosis, Atrial Fibrillation, Atrial Flutter
- Trial name
- COAG (NCT00839657)
- Testing
- Genotype-guided dosing algorithm for warfarin, Clinical-guided dosing algorithm for warfarin
- Where
- 18 sites in United States
- Volunteers
- 1,015 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Arrhythmias, Cardiac, Atrial Fibrillation and Flutter
Aino ECG Ambulatory Study
The study includes collection of data from patients referred to a therapeutic evaluation in Tays Sydänkeskus Oy (Heart Center Co, Tampere University Hospital) or another unit of Sydänkeskus (hereafter the Heart Hospital) due to…
- Trial name
- NCT05008601
- Testing
- Wrist-word optical heart rate and ECG measurement device
- Where
- Finland
- Volunteers
- 31 people
- Sponsor
- PulseOn Oy
Atypical Atrial Flutter, Atrial Flutter
Pulsed-Field Ablation for Recurrent Atypical Atrial Flutter
Recurrent atypical atrial flutter (AFL) after prior atrial fibrillation or flutter ablation remains challenging to treat, and conventional radiofrequency ablation may be limited by incomplete lesion formation and risk of…
- Trial name
- NCT07362134
- Testing
- Point-by-point pulsed-field catheter ablation
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Long QT Syndrome, Sinus Bradycardia
A Study to Evaluate Accuracy and Validity of the Chang Gung ECG Abnormality Detection Software
"Chang Gung ECG Abnormality Detection Software" is a is an artificial intelligence medical signal analysis software that detect whether patients have abnormal ECG signals of 14 diseases by static 12-lead ECG.
- Conditions
- Long QT Syndrome, Sinus Bradycardia, Sinus Tachycardia, Premature Atrial Complexes
- Trial name
- NCT05903313
- Testing
- Chang Gung ECG Abnormality Detection Software
- Where
- Taiwan
- Volunteers
- 4,306 people
- Sponsor
- Chang Gung Memorial Hospital
Cardiac Arrhythmias, Atrial Fibrillation and Flutter
Increasing Detection of Sub-Clinical Atrial Fibrillation in Defibrillator Patients With the Use of a VDD-ICD Lead
This study aims to compare the Dx-ICD system (experimental) to standard VVI-ICD (control) on the ability to diagnose silent AF in patients without prior AF receiving an ICD for standard indications.
- Conditions
- Cardiac Arrhythmias, Atrial Fibrillation and Flutter, Cardiovascular Diseases, Implantable Cardioverter-Defibrillators
- Trial name
- Dx-AF (NCT03110627)
- Testing
- VDD ICD (experimental group), Single chamber VVI ICD (control group)
- Where
- 9 sites in Canada
- Volunteers
- 188 people
- Sponsor
- Unity Health Toronto