Clinical trials: Atrium; Flutter
Heart Rate and Rhythm Disorders
Comparison of Diltiazem and Metoprolol in the Management of Acute Atrial Fibrillation or Atrial Flutter
Acute atrial fibrillation is the most common sustained, clinically significant dysrhythmia encountered in the emergency department (ED) and the most common dysrhythmia treated by emergency physicians.
- Trial name
- DiME (NCT01914926)
- Testing
- Metoprolol, Diltiazem
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Antonios Likourezos
Postoperative Atrial Fibrillation
Rate Control Versus Rhythm Control For Postoperative Atrial Fibrillation
The purpose of this study is to compare the therapeutic strategies of rate control versus rhythm control in cardiac surgery patients who develop in-hospital postoperative atrial fibrillation or atrial flutter (AF).
- Trial name
- NCT02132767
- Testing
- Amiodarone, DC-cardioversion, Rate Control
- Where
- 23 sites in United States, Canada
- Volunteers
- 523 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Atrial Flutter
Clinical Evaluation of the Blazer® Open-Irrigated Catheter for Treatment of Type 1 Atrial Flutter
The purpose of the BLOCk-CTI study is to evaluate the safety and effectiveness of the Blazer® Open-Irrigated Ablation Catheter for the treatment of sustained or recurrent type 1 atrial flutter.
- Trial name
- BLOCk-CTI (NCT01253200)
- Testing
- Blazer® Open-Irrigated Ablation Catheter, Control Catheter
- Where
- 26 sites in United States
- Volunteers
- 302 people
- Sponsor
- Boston Scientific Corporation
Atrial Fibrillation, Atrial Flutter
Impact of an Atrial Fibrillation Decision Support Tool (AFDST) on Thromboprophylaxis for Atrial Fibrillation
Study objective was to improve decision-making and thromboprophylaxis for patients with Atrial Fibrillation (AF) by developing and implementing a computerized decision support tool for individual patient-level decision-making…
- Trial name
- NCT02524977
- Testing
- Decision Support, Educational Intervention Only
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Atrial Fibrillation, Arrhythmias, Cardiac
Apple Heart Study: Assessment of Wristwatch-Based Photoplethysmography to Identify Cardiac Arrhythmias
The Apple Heart Study (AHS) is a research study conducted to evaluate whether the Apple Heart Study App can use data collected on the Apple Watch to identify irregular heart rhythms, including those from potentially serious heart…
- Conditions
- Atrial Fibrillation, Arrhythmias, Cardiac, Atrial Flutter
- Trial name
- NCT03335800
- Testing
- Apple Heart Study App
- Where
- United States
- Volunteers
- 419,927 people, healthy volunteers welcome
- Sponsor
- Apple Inc.
Atrial Fibrillation, Atrial Flutter
Colchicine For The Prevention Of Perioperative Atrial Fibrillation In Patients Undergoing Thoracic Surgery (COP-AF)
The prevention of perioperative atrial fibrillation (AF) and myocardial injury after non-cardiac surgery (MINS) has the potential to reduce mortality, stroke, and hospital stays in patients undergoing major thoracic surgery.
- Conditions
- Atrial Fibrillation, Atrial Flutter, Myocardial Injury After Non-Cardiac Surgery
- Trial name
- COP-AF (NCT03310125)
- Testing
- Active Colchicine
- Where
- 46 sites in United States, Austria and 9 more
- Volunteers
- 3,209 people
- Sponsor
- Population Health Research Institute
Current or Recent History of Atrial Fibrillation
Genetically Targeted Therapy for the Prevention of Symptomatic Atrial Fibrillation in Patients With Heart Failure
This study is being done to compare the effects of bucindolol hydrochloride (bucindolol) to metoprolol succinate (Toprol-XL) on the recurrence of symptomatic atrial fibrillation/atrial flutter in patients with heart failure who…
- Trial name
- GENETIC-AF (NCT01970501)
- Testing
- bucindolol hydrochloride, metoprolol succinate
- Where
- 97 sites in United States, Canada and 4 more
- Volunteers
- 267 people
- Sponsor
- ARCA Biopharma, Inc.
Atrial Fibrillation, Atrial Flutter
Apixaban for the Prevention of Stroke in Subjects With Atrial Fibrillation
The trial seeks to determine if apixaban, an investigational anticoagulant (blood-thinner) is as effective as standard therapy (warfarin) in preventing stroke and systemic embolism in subjects with atrial fibrillation and risk…
- Trial name
- ARISTOTLE (NCT00412984)
- Testing
- warfarin, apixaban
- Where
- 1,111 sites in United States, Argentina and 39 more
- Volunteers
- 20,976 people
- Sponsor
- Bristol-Myers Squibb
Typical Atrial Flutter
Atrial Flutter Ablation With Contact Therapy Cool Path Ablation System Along With EnSite Velocity Contact System
To demonstrate that the use of Contact Therapy™ Cool Path™ ablation catheter in conjunction with the EnSite Velocity Contact Technology for the treatment of typical atrial flutter Does not result into unacceptable risk of…
- Trial name
- CONTACT_AFL (NCT01401361)
- Testing
- Treatment Arm
- Where
- 20 sites in United States, Canada
- Volunteers
- 150 people
- Sponsor
- Abbott Medical Devices
Atrial Flutter
Cardiac Electrophysiological Study
The purpose of the study is to measure the effects of AZD1305 on cardiac electrophysiological properties and intracardiac pressures
- Trial name
- NCT00616629
- Testing
- AZD1305
- Where
- 13 sites in Denmark, Finland and 2 more
- Volunteers
- 55 people
- Sponsor
- AstraZeneca
Atrial Fibrillation and Flutter
Oral vs Intravenous Diltiazem for Rapid Atrial Fibrillation/Flutter Trial
The primary objective of this study is to compare the incidence of rate control (defined as: HR <110 beats/min or conversion to sinus rhythm) at 2 hours after medication administration between oral immediate release diltiazem and…
- Trial name
- OVID RAF (NCT03472495)
- Testing
- Diltiazem Oral Product, Diltiazem Injectable Product
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Virginia Commonwealth University
Atrial Flutter
Antero-posterior Versus Antero-lateral Electrode Position for Electrical Cardioversion of Typical Atrial Flutter
The aim of this study is to identify the one electrode position out of two most commonly used for external electrical cardioversion of typical atrial flutter, which needs less delivered energy and less needed number of shocks for…
- Trial name
- APOVERSAL (NCT00860314)
- Testing
- external electrical cardioversion (with antero-posterior electrode position), external electrical cardioversion (with antero-lateral electrode position)
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Atrial Fibrillation, Atrial Flutter
Comparison of Bolus Dosing of Methohexital and Propofol in Elective Direct Current Cardioversion
A randomized, open-blinded, prospective study to evaluate the timeliness and safety of direct current cardioversion (DCCV) when using methohexital when compared to the more often used propofol.
- Trial name
- NCT04187196
- Testing
- Propofol, Methohexital
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Wake Forest University Health Sciences
Atrial Fibrillation
A Dose-range Finding Study of MAA868 in Patients With Atrial Fibrillation
This study is a multicenter, randomized, subject and Investigator-blinded, placebo-controlled, parallel-group, multiple ascending dose-ranging study to evaluate the safety, tolerability, pharmacokinetics (PK), and…
- Trial name
- NCT04213807
- Testing
- MAA868 Cohort 1, MAA868 Cohort 2, MAA868 Cohort 3
- Where
- 6 sites in United States
- Volunteers
- 28 people
- Sponsor
- Anthos Therapeutics, Inc.
Atrial Fibrillation or Atrial Flutter
Multipolar Mapping and Atrial Arrhythmias
This clinical investigation utilizes the Constellation Full Contact Mapping catheter in the left and right atria to explore atrial signal characteristics that can guide atrial fibrillation and atrial flutter ablation procedures…
- Trial name
- NCT02307188
- Testing
- Constellation Full Contact Mapping Catheter
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Angelo Biviano
Atrial Fibrillation, Atrial Flutter
ArcticLine Feasibility Study
The purpose of the ArcticLine Feasibility Study is to collect preliminary safety and effectiveness data on the ArcticLine Catheter.
- Trial name
- NCT03604263
- Testing
- ArcticLine Cardiac Cryoablation Catheter
- Where
- 4 sites in United States, Canada
- Volunteers
- 17 people
- Sponsor
- Medtronic Cardiac Ablation Solutions
Atrial Fibrillation With Rapid Ventricular Response, Hypotension Drug-Induced
Diltiazem in the Treatment of Atrial Fibrillation or Atrial Flutter With Rapid Ventricular Rate
The purpose of this study is to see how well calcium pre-treatment works for decreasing incidence of drug-induced hypotension after diltiazem administration for treatment of atrial flutter with rapid ventricular rate.
- Trial name
- AFFRVR (NCT05661942)
- Testing
- Calcium pre-treatment
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Wake Forest University Health Sciences
Arrhythmia
Qubic Stim Cardiac Stimulator in China
106 subjects selected from 3 study sites in China are with indications for intracardiac electrophysiological examination. The trial is to prove the clinical effectiveness and safety of Qubic Stim Cardiac Stimulator in Chinese…
- Trial name
- NCT04390841
- Testing
- Cardiac Stimulator
- Where
- 3 sites in China
- Volunteers
- 106 people
- Sponsor
- Biotronik (Beijing) Medical Device Ltd.
Atrial Fibrillation, Arrhythmias, Cardiac
Evaluation of the Use of Apple Watch Features for Identification of Cardiac Arrhythmias
This post-marketing study is conducted to characterize the ability of Apple Watch rhythm analysis software to identify Atrial Fibrillation (AF) and facilitate subsequent clinical evaluation among users who contact AppleCare.
- Conditions
- Atrial Fibrillation, Arrhythmias, Cardiac, Atrial Flutter
- Trial name
- NCT03769207
- Testing
- Ambulatory ECG
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Apple Inc.
Atrial Fibrillation, Atrial Flutter
Assessment of the Sphere-9™ Catheter and Affera Mapping and Ablation System for Treatment of Atrial and Ventricular Arrhythmias
A prospective, single-arm, multi-center, safety and performance assessment of the Sphere-9™ Catheter and the Affera Mapping and RF Ablation System to treat Atrial Arrhythmias
- Conditions
- Atrial Fibrillation, Atrial Flutter, Ventricular Tachycardia
- Trial name
- NCT04211441
- Testing
- Catheter mapping and ablation with the Sphere-9 Catheter and Affera Mapping and Ablation System
- Where
- 2 sites in Czechia
- Volunteers
- 74 people
- Sponsor
- Medtronic Cardiac Ablation Solutions