Clinical trials: Atrophic Acne Scarring
ATROPHIC ACNE SCARS
Comparison Of Outcome Of Microneedling With Autologous PRP Vs Microneedling With Topical Insulin In Treatment Of Post Acne Atrophic Scars.
Microneedling with topical INSULIN is a simple, effective tool for building body's new collagen layers and thus an alternative to all erosive techniques such as lasers, peels.
- Trial name
- NCT06002854
- Testing
- PRP( platelet rich plasma) and Insulin human
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Acne Scars
Evaluation of Juläine (TM) for the Treatment of Atrophic Facial Acne Scars
This study aims to evaluate the effectiveness and safety of Juläine, an injectable medical device made of polylactic acid, for treating facial acne scars.
- Trial name
- NCT07058883
- Testing
- Juläine
- Where
- 2 sites in Poland
- Volunteers
- 55 people
- Sponsor
- Nordberg Medical AB
Acne Scars - Atrophic
Nano Fat Injection With or Without Fractional Carbon Dioxide Laser in Acne Scars
Assessment of nano fat grafting combined with carbon dioxide laser resurfacing versus nano fat grafting alone in treating facial atrophic acne scars
- Trial name
- NCT05985265
- Testing
- Fat grafting
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Atrophic Acne Scars
Treatment of Atrophic Acne Scars With Platelet-Rich Plasma and Skin Needling
Investigators will collect blood specimens from the participating patients and then blood samples will be centrifuged in order to collect platelet-rich plasma which is going to be injected in the atrophic acne scars.
- Trial name
- NCT02798016
- Testing
- Platelet-Rich Plasma, Micro-needling
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- Damascus University
Subcision, Calcium Hydroxylapatite
Subcision Followed by Diluted Calcium Hydroxylapatite Injection Versus Subcision Followed by Painting CROSS TCA Technique for the Treatment of Atrophic Acne Scars
This study aimed to compare the safety and efficacy of subcision followed by diluted calcium hydroxyapatite injection versus subcision followed by the painting original chemical reconstruction of skin scars (CROSS) technique…
- Conditions
- Subcision, Calcium Hydroxylapatite, Trichloroacetic Acid, Atrophic Acne Scar
- Trial name
- NCT07028567
- Testing
- Calcium hydroxylapatite filler, Painting chemical reconstruction of skin scars trichloroacetic acid technique
- Where
- Egypt
- Volunteers
- 13 people
- Sponsor
- Tanta University
Atrophic Acne Scar
Evaluation of the Efficacy and Safety of Microneedling Combined With Botulinum Toxin-A Versus Meso-Botox Injection in the Treatment of Atrophic Acne Scars: A Split-face Comparative Study
Post-acne scars are psychologically disappointing and therapeutically challenging condition. No standard treatment for atrophic acne scars. Micro-Botox, is a highly diluted BTX-A which could be injected safely intra-dermally.
- Trial name
- NCT06544993
- Testing
- Meso-botox
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sohag University
Acne Scars - Atrophic
Stromal Vascular Fraction Enriched PRP in Treatment of Post-acne Scars
in a split face fashion, 30 patients will be randomized into 3 groups: Group A: rt side treated with SVF enriched PRP, lt side treated with prp Group B: rt side treated with SVF enriched PRP, lt side treated with SVF Group C: rt…
- Trial name
- NCT06524011
- Testing
- Stromal vascular fraction (SVF) enriched platelet rich plasma (PRP) versus each alone
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Atrophic Acne Scars
A Pilot Study to Evaluate the Safety and Effectiveness of Microneedling and Bellafill to Treat Facial Acne Scars
This is an open-label, randomized, multicenter, prospective trial assessing the efficacy and safety of microneedling treatment alone vs.
- Trial name
- NCT02643628
- Testing
- Microneedling, Microneedling followed by Bellafill treatment
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Suneva Medical, Inc.
Acne Scars - Mixed Atrophic and Hypertrophic, Wrinkle
Fractional Radiofrequency for the Treatment and Reduction of Acne Scars and Wrinkles
The objective of this clinical study is to evaluate the efficacy of fractional RF for the treatment and reduction of acne scarring or facial wrinkles.
- Trial name
- NCT04057768
- Testing
- Venus Viva
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Venus Concept
Atrophic Acne Scars, Acne Vulgaris
Microneedling With Glycolic Acid or Trichloroacetic Acid for Atrophic Acne Scars
Atrophic acne scars are depressed scars that can remain after acne has healed. Microneedling is a procedure that uses very small needles to create controlled micro-injuries in the skin, which may stimulate collagen production and…
- Trial name
- NCT07797517
- Testing
- Microneedling only, Microneedling with Glycolic Acid 35% Peel, Microneedling with Trichloroacetic Acid 15% Peel
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Atrophic Acne Scar
Simultaneous Versus Sequential Fractional CO2 Laser and Subcision Combination for Post-acne Atrophic Scars: A Split-face Comparative Study.
Acne vulgaris, a disease of the pilosebaceous unit, is estimated to afflict 9.4% of the global population, making it the eighth most prevalent and third most significant disease according to the global burden of disease.
- Trial name
- NCT05688202
- Testing
- Simultaneous combination of fractional CO2 laser and subcision, Sequential combination of fractional CO2 laser and subcision, Fractional CO2 laser
- Where
- Vietnam
- Volunteers
- 34 people
- Sponsor
- Ho Chi Minh City Hospital of Dermato-Venereology
Acne, Atrophic Scar
Comparison of Picosecond Lasers vs. Ablative Fractional Er:YAG Lasers in Treating Atrophic Scar
The 1064-nm Nd:YAG picosecond lasers using fractional micro-lens array (P-MLA) was a promising therapy for skin resurfacing. However, no studies have compared P-MLA with ablative fractional 2940-nm Er:YAG lasers (AF-Er) in…
- Trial name
- NCT05686603
- Testing
- a fractional 1064-nm neodymium-doped yttrium aluminum garnet (Nd:YAG) picosecond laser with MLA handpiece, a ablative fractional 2940-nm Er:YAG laser
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Atrophic Acne Scarring
Poly-L-Lactic Acid in Atrophic Acne Scars
Background: Management of atrophic acne scars remains challenging due to their heterogeneous morphology and suboptimal response to conventional therapies.
- Trial name
- NCT07523217
- Testing
- injectable PLLA, PLLA threads
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Skin Care
Dynamic Optical Coherence Tomography(D-OCT) Aging Study: A Preliminary Evaluation of Structural Differences Between Young and Aged Skin, Cellulite and Atrophic Acne Scars in Female Caucasian Subjects With Fitzpatrick Skin Types I-III Utilizing Non-invasive in Vivo D-OCT.
This single-center clinical study is being conducted over the course of 2 weeks to conduct an exploratory pilot study as a preliminary evaluation of D-OCT's ability to measure skin changes from aging.
- Trial name
- NCT03767400
- Testing
- Skin Imaging, Facial Cleanser
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Allergan
Acne Scars - Mixed Atrophic and Hypertrophic, Scar
Impact of Tripolar Radiofrequency on Acne Scar
The aim of this study is to investigate the therapeutic efficacy of tripolar radiofrequency on acne scar
- Conditions
- Acne Scars - Mixed Atrophic and Hypertrophic, Scar, Radiofrequency
- Trial name
- NCT06492356
- Testing
- Tripolar radiofrequency therapy, medical treatment
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Melasma, Acne Scars - Mixed Atrophic and Hypertrophic
Comparative Effects Of Trichloroacetic Chemical Peel And Fractional Laser
More than aesthetics, the search for orofacial harmonization treatments has increased when the negative emotional impact of some facial conditions such as melasma and acne scars is recognized.
- Conditions
- Melasma, Acne Scars - Mixed Atrophic and Hypertrophic, Resurfacing, Rejuvenation
- Trial name
- NCT07036302
- Testing
- 35% TCA combined with croton oil peel, Isolate 35% TCA peel, Erbium-YAG laser
- Where
- 2 sites in Brazil
- Volunteers
- 120 people
- Sponsor
- Jose Roberto Cortelli
Acne Scars - Mixed Atrophic and Hypertrophic
Safety and Efficacy of Sofwave Treatment for Acne Scars Appearance Improvement
Open-label, non-randomized, prospective, multi-center, self-controlled clinical study with masked evaluation.
- Trial name
- NCT05358860
- Testing
- Sofwave
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sofwave Medical LTD
Acne Scars - Mixed Atrophic and Hypertrophic
Treatment of Acne Scars With Fractional CO2 Laser Versus Radio-frequency Microneedling
The study is a prospective, randomized, controlled, intra-person split-face trial with blinded evaluations. The objective is to compare efficacy and adverse effects of ablative fractional CO2 laser resurfacing versus…
- Trial name
- NCT04252352
- Testing
- Ablative fractional CO2 laser resurfacing/Radio-frequency microneedling
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Acne, Scar
Comparison of Treatments for Atrophic Acne Scars
Acne scars have high prevalence, significant impact on quality of life and are a therapeutic challenge for dermatologists. Previous studies have shown promising results for the treatment of acne scars with non-ablative fractional…
- Trial name
- NCT02025088
- Testing
- Laser, Microneedling
- Where
- Brazil
- Volunteers
- 23 people
- Sponsor
- Thaís Hofmann Cachafeiro
Acne Vulgaris, Scars
Erbium-YAG Laser Versus Platelet Rich Plasma in the Treatment of Atrophic Acne Scars
This study aim to assess the efficacy of Er-YAG laser 2940nm and PRP as a single line of treatment in comparison with combined treatment in atrophic post acne scars.
- Trial name
- NCT03933033
- Testing
- Fractional Erbium Yağ Laser, Platelet Rich Plasma
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Aswan University Hospital