Clinical trials: Auricular Stimulation, open to volunteers
Type 2 Diabetes, Mild Cognitive Impairment
Transcutaneous Auricular Vagus Nerve Stimulation in Type 2 Diabetes With Mild Cognitive Impairment
This study is a 24-week, single-center, randomized, double-blind, sham-controlled, parallel-group clinical trial. A total of 38 patients with type 2 diabetes and mild cognitive impairment were enrolled and randomly assigned in a…
- Trial name
- NCT07642518
- Testing
- active transcutaneous auricular vagus nerve stimulation
- Volunteers
- 38 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Post-Concussion Syndrome, COVID Long-Haul
Percutaneous Electrical Nerve Field Stimulation (PENFS) in Patients With Post Concussion Syndrome (PCS)
The purpose of this study is to test the effect of Auricular Percutaneous Electrical Nerve Field Stimulation (a Neurostim device) on children with pain and Post Concussion symptoms.
- Conditions
- Post-Concussion Syndrome, COVID Long-Haul, COVID-19
- Trial name
- NCT04978571
- Testing
- percutaneous electrical nerve-field stimulation, PENFS, percutaneous electrical nerve-field stimulation, PENFS (COVID active device)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Children's Hospital of Orange County
Nicotine Dependence, Nicotine Withdrawal
Auricular Stimulation for Nicotine Withdrawal in Psychiatric Inpatients
The goal of this clinical trial is to evaluate the feasibility and preliminary effectiveness of auricular acupressure (ear seeds) combined with nicotine replacement therapy (NRT) in psychiatric inpatients (both male and female…
- Conditions
- Nicotine Dependence, Nicotine Withdrawal, Tobacco Use Disorder, Anxiety
- Trial name
- NCT07466875
- Testing
- Auricular acupressure, Nicotine Replacement Therapy (Nicotine patch plus NRT gum or lozenge)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chiao-Chiao Liao
Dyspepsia
High Resolution Gastric Mapping and Gastroduodenal Manometry
Dyspepsia is a common problem attributed to gastric sensorimotor dysfunctions ie, delayed, or less frequently rapid gastric emptying (GE), impaired gastric accommodation, and increased gastric sensation.
- Trial name
- NCT06941545
- Testing
- Alimetry, tVNS, Gastroduodenal Manometry
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Social Anxiety Disorder, Social Fear
Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)Therapy for Social Anxiety Disorder
This clinical trial aims to evaluate the efficacy and safety of transcutaneous auricular vagus nerve stimulation (taVNS) in patients with social anxiety disorder (SAD).
- Trial name
- taVNS (NCT07772401)
- Testing
- taVNS
- Where
- 2 sites in China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Persistent Post-concussive Symptoms
Transcutaneous Auricular Vagus Nerve Stimulation for Persistent Post-concussion Symptoms
Persistent post-concussive symptoms (PPCS) affect a significant proportion of individuals following a concussion, leading to debilitating impacts on their quality of life and work capacity.
- Trial name
- taVNS-PPCS (NCT07017257)
- Testing
- Active taVNS
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- University of Liege
Sepsis
Transcutaneous Auricular Vagus Nerve Stimulation as Adjuvant Treatment for Sepsis Patients
The goals of this randomized clinical trial are to investigate the effects of transcutaneous auricular vagus nerve stimulation (taVNS) combined with standard intensive care on systemic organ function in septic patients, and…
- Trial name
- TaVNS-Sepsis (NCT07051694)
- Testing
- taVNS
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Third Military Medical University
Stroke, Dysphagia
Auricular Vagus Nerve Stimulation and Post-Stroke Dysphagia in Older Adults
This study investigates the effect of non-invasive transcutaneous auricular vagus nerve stimulation (tVNS-E) on swallowing rehabilitation in patients over 70 years old after stroke.
- Trial name
- SVA-DPA (NCT07428590)
- Testing
- tVNS-E active device, tVNS-E inactive device
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Psoriatic Arthritis
Transcutaneous Auricular Vagus Nerve Stimulation in Psoriatic Arthritis
This prospective single-center interventional study aims to investigate the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on disease activity, pain, quality of life, autonomic dysfunction symptoms, and…
- Trial name
- NCT07653009
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Marmara University
Motion Sickness
Evaluation of a Device to Reduce Motion Sickness and Spatial Disorientation
The purpose of this research study is to learn how a wearable nerve stimulation device, the Spark Biomedical's Sparrow Ascent System™, impacts the development of spatial disorientation and/or motion sickness in a healthy…
- Trial name
- NCT06892340
- Testing
- Transcutaneous Auricular Neurostimulation device
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing
Opioid Withdrawal, Opioid Use Disorder (OUD)
Sparrow Link Neuromodulation Device for Opioid Withdrawal Management in Hospitalized Adults With Opioid Use Disorder
This study is evaluating the Sparrow Link, a wearable device that delivers gentle electrical signals to nerves in the outer ear (a technique known as transcutaneous auricular neurostimulation, or tAN).
- Trial name
- NCT07079826
- Testing
- Sparrow Link (Active tAN)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Payel Roy
Psychiatric Disorder
Pilot Study on the Acceptability of Auricular Vagus Nerve Neurostimulation in Adolescents
Non-suicidal self-injury (NSSI) are acts defined by the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders 5) as intentional and deliberate, occurring outside a psychotic state and directly causing moderate injury.
- Trial name
- NEUROMUTE (NCT06433583)
- Testing
- transcutaneous auricular vagal nerve stimulation
- Where
- 2 sites in France
- Volunteers
- 22 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Parkinson Disease, Apathy
Respiratory-gated Transcutaneous Auricular Vagus Nerve Stimulation for Improving Apathy in Parkinson's Disease
The goal of this clinical trial is to learn whether 100HZ respiratory-gated vagus nerve stimulation (RAVANS) can improve the non-motor symptoms in people with Parkinson's disease (PD).
- Conditions
- Parkinson Disease, Apathy, Non-motor Symptoms, Vagus Nerve Stimulation
- Trial name
- NCT07118956
- Testing
- Active RAVANS
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Insomnia
Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for Insomnia During the Withdrawal-Rehabilitation Period of Methamphetamine Use Disorder
The Department of Acupuncture-Moxibustion, the First Affiliated Hospital of Zhejiang Chinese Medical University is conducting a clinical research project entitled "Randomized Controlled Clinical Trial of Transcutaneous Auricular…
- Trial name
- NCT07899957
- Testing
- taVNS
- Volunteers
- 96 people
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Motor Impairment, Motor Impairments
Transcutaneous Auricular Vagus Nerve Stimulation in Patients With Stroke
This study will evaluate the effects of transcutaneous vagus nerve stimulation in combination with physical rehabilitation on upper limb motor function of patients with stroke.
- Conditions
- Motor Impairment, Motor Impairments, Stroke, Stroke; Sequelae
- Trial name
- INPULSE (NCT06895005)
- Testing
- Transcutaneous auricular vagus nerve stimulation + rehabilitation therapy
- Where
- Colombia
- Volunteers
- 30 people
- Sponsor
- Fundación Cardiovascular de Colombia
Head and Neck Neoplasms, Xerostomia
Foot Reflexology and Ta-VNS for Symptom Management in Head and Neck Cancer During CCRT
Head and neck cancer (HNC) patients undergoing concurrent chemoradiotherapy (CCRT) frequently experience pain, xerostomia, fatigue, sleep disturbance, and other treatment-related toxicities that impair quality of life and…
- Conditions
- Head and Neck Neoplasms, Xerostomia, Cancer-related Fatigue, Pain
- Trial name
- NCT07711626
- Testing
- True Foot Reflexology, True ta-VNS, True Auricular Acupressure
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Tzu Chi University
Rheumatoid Arthritis (RA), Transcutaneous Vagus Nerve Stimulation
the Effect and Mechanism of Percutaneous Auricular Electrical Stimulation in Preventing Central Sensitization Pain in Patients With Rheumatoid Arthritis
This multicenter, randomized, double-blind, sham-controlled trial aimed to evaluate the preventive efficacy of transcutaneous auricular vagus nerve stimulation (taVNS) against central-sensitization-related pain in high-risk…
- Trial name
- taVNS for Pain (NCT07870564)
- Testing
- taVNS
- Volunteers
- 124 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Primary Dysmenorrhea (PD)
Effects of Transcutaneous Tibial and Auricular Vagus Nerve Stimulation in Females With Primary Dysmenorrhea
Primary dysmenorrhea is a common gynecological condition characterized by painful menstrual cramps that can negatively affect daily activities and quality of life.
- Trial name
- NCT07834658
- Testing
- Transcutaneous Tibial Nerve Stimulation (TTNS), Transcutaneous Auricular Vagus Nerve Stimulation (TaVNS), TTNS+TaVNS
- Volunteers
- 66 people
- Sponsor
- Riphah International University
Chronic Low Back Pain
Auricular Vagus Nerve Stimulation in Patients With High Impact Chronic Low Back Pain
The goal of this clinical trial is to evaluate whether auricular vagus nerve stimulation using the VIVO® device can improve function and reduce pain in adults with high-impact chronic low back pain when added to standard medical…
- Trial name
- VIVO (NCT07681336)
- Testing
- Auricular Vagus Nerve Stimulation (VIVO®), Standard of Care (Investigator Choice)
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Chronic Kidney Diseases
Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in Chronic Kidney Disease (CKD)
30 patients will participate in a prospective randomized clinical trial to test the safety, tolerability and efficacy of transcutaneous auricular vagus nerve stimulation (taVNS) for autonomic nervous system (ANS) dysfunction in…
- Trial name
- NCT06927024
- Testing
- Active taVNS
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- NYU Langone Health