Clinical trials: Autism
Autism Spectrum Disorder
A Study to Investigate the Efficacy and Safety of Balovaptan (RO5285119) in Participants With Autism Spectrum Disorder (ASD)
For participants enrolled prior to Version 6 of the protocol: This was a Phase II multi-center, randomized, double-blind, 24-week, 3-arm, parallel group, placebo-controlled study to investigate the efficacy, safety, and…
- Trial name
- NCT02901431
- Testing
- RO5285119
- Where
- 45 sites in United States
- Volunteers
- 339 people
- Sponsor
- Hoffmann-La Roche
Autistic Disorder
Use of a Family Navigator in Families With Children Newly Diagnosed With Autism Spectrum Disorder
The purpose of this study is to see whether or not Family Navigators, who 1 ) help families after their child is diagnosed with autism and help them get autism specific services for their child 2) help families identify barriers…
- Trial name
- NCT01340092
- Testing
- Family Navigator
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Boston Medical Center
Autism Spectrum Disorder, Depression
Group Depression Treatment for Autistic Youth
Higher rates of depression are reported by autistic adolescents as compared to their non-autistic peers, which is problematic given adverse outcomes (e.g., negative self-esteem, lower academic performance) that are associated…
- Conditions
- Autism Spectrum Disorder, Depression, Suicidal Ideation, Self Esteem
- Trial name
- NCT05430022
- Testing
- Autism-adapted Group Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Vanderbilt University Medical Center
Autism, Autism Spectrum Disorder
The Impact of Sensory Integration on Attention in Autism
The study aims to examine how the mode of presentation of visual and auditory stimuli-separate or simultaneous-affects accuracy and reaction time in visual-auditory association in participants with Autism Spectrum Condition (ASC)…
- Trial name
- NCT06872229
- Testing
- Autism Spectum Conditions - intervention, Typical Development - intervention
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Autism Spectrum Disorders
National Study on Autism Spectrum Disorder in China
The aims of the national population-based study on Autism Spectrum Disorder (ASD) include: (1) to understand the overall prevalence of ASD in children aged 6-12 years in 8 cities (n=120,000), (2) to explore environmental and…
- Trial name
- NCT02200679
- Where
- 8 sites in China
- Volunteers
- 143,755 people
- Sponsor
- Fudan University
Pain Management, Autism Spectrum Disorder (ASD)
Prospective Study to Determine the Prevalence of Signs of Central Sensitization in Adults With ASD Without Intellectual Developmental Disorders
Autism is a neurodevelopmental disorder (NDD) characterized by two key features: persistent deficits in communication and social interaction, and restricted, repetitive patterns of behavior, interests, and activities.
- Trial name
- Presca (NCT07495761)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Groupe Hospitalier Mutualiste de Grenoble
Autism Spectrum Disorder
Impact of Air Quality on the Effectiveness of Standard of Care Therapy in Children With Autism Spectrum Disorder: A Prospective Longitudinal Study
1. Air quality is a growing concern for health and environment and is one of the modifiable environmental factors. There is growing evidence that a complex interplay of genetic and epigenetic factors like environmental factors…
- Trial name
- NCT06913751
- Testing
- standard of care
- Volunteers
- 66 people
- Sponsor
- All India Institute of Medical Sciences
Anxiety, Attention Deficit Hyperactivity Disorder (ADHD)
Pilot Trial of a Social Skills Group Treatment (Secret Agent Society Program)
Several independent evaluations have supported the effectiveness of the Secret Agent Society (SAS) Program in improving the social-emotional functioning of children with Autism Spectrum Disorders (ASD) in clinic- (Beaumont \&…
- Conditions
- Anxiety, Attention Deficit Hyperactivity Disorder (ADHD), Autistic Spectrum Disorder (ASD)
- Trial name
- NCT02574273
- Testing
- Secret Agent Society (SAS) Program, Waitlist Group / Treatment As Usual
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Weill Medical College of Cornell University
Autism, Pain
Pain in Adults With Autism Spectrum Disorder
Pain insensibility is often described in people with autism. The aim of this study is to test the pain perception in adults with autistic spectrum disorder without intellectual disability.
- Trial name
- DOUPA (NCT02277756)
- Testing
- thermode
- Where
- France
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Intellectual Disability, Attention Deficit Hyperactivity Disorder
Evaluation of a Home-based Parenting Support Program: Parenting Young Children
Background: Parents with intellectual and developmental disabilities (IDDs) have a tendency to provide insufficient caregiving and often need parenting support to prevent neglect and child removal.
- Conditions
- Intellectual Disability, Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
- Trial name
- PYC (NCT05935722)
- Testing
- Parenting Young Children, Treatment as Usual
- Where
- 5 sites in Sweden
- Volunteers
- 60 people
- Sponsor
- Örebro University, Sweden
Autism Spectrum Disorder
An Exploratory Clinical Study of a Low-dose Buprenorphine Patch for the Treatment of Autism Spectrum Disorders
This study evaluates the safety and efficacy of low-dose buprenorphine in patients with ASD by using standard ASD symptom assessment methods (e.g., SRS-2 and ABC) as well as AI-assisted analyses utilizing exploratory gaze…
- Trial name
- NCT06772324
- Testing
- NORSPAN Buprenorphine Transdermal Patchs for Very-low dose group, NORSPAN Buprenorphine Transdermal Patchs for Lower dose group, NORSPAN Buprenorphine Transdermal Patchs for higher dose group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Sixth Hospital
Autism Spectrum Disorder
An Online Evaluation of Work Chat
This study is aiming to see if it is feasible for the intervention Work Chat to be delivered in a completely online setting to adults with autism spectrum disorder.
- Trial name
- NCT05949086
- Testing
- Work Chat
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Autism Spectrum Disorder
Effect of Virtual Reality-based Training on Balance and Walking in Youth With Autism Spectrum Disorder
The goal of this clinical trial is to assess the effect of short-term (3 days/week for 2 weeks) Virtual Reality (VR) active video gaming intervention on static and dynamic balance, versus traditional balance training exercises…
- Trial name
- NCT06023563
- Testing
- Virtual reality active video gaming using Nintendo switch sports, Standard physical therapy balance exercises
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Indiana University
Obsessive Compulsive Disorder, Autism Spectrum Disorder
Internet Delivered CBT for OCD in Adolescents With ASD - A Clinical Case Series
The aim of this study is to test the feasibility and acceptability of an internet-delivered cognitive behavior therapy (ICBT) intervention originally developed for neurotypical adolescents with obsessive compulsive disorder (OCD)…
- Trial name
- NCT02660099
- Testing
- Internet-delivered Cognitive Behavior Therapy
- Where
- 2 sites in Sweden
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Autism Spectrum Disorder, Mitochondrial Pathology
Transgenerational Metabolic-Immune Biomarkers of Neurological and Neurodevelopmental Disorders
The study involves up to 5 visits for a fasting blood draw, behavioral assessments, and/or questionnaires. Other samples may be collected when appropriate. This study is currently recruiting.
- Conditions
- Autism Spectrum Disorder, Mitochondrial Pathology, Epilepsy, Brain Tumor
- Trial name
- NCT04322734
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Southwest Autism Research & Resource Center
Autism Spectrum Disorder
Sand Play vs. Cuff Training: Visual-Motor Skills in Autism
This study compares Image-Sand Play Therapy and Tabletop Training with Weighted Cuffs for improving Visual-Motor Integration (VMI) in children with autism.
- Trial name
- NCT06943248
- Testing
- Image-Sand Play Therapy, Table Top Training Program with Weighted Cuff
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Autism
A Study of Oxytocin in Children and Adolescents With Autistic Disorder
The investigators propose to conduct this pilot study to evaluate oxytocin as a supplemental treatment for improving social difficulties in individuals with autism.
- Trial name
- Oxytocin (NCT01308749)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of North Carolina, Chapel Hill
Autism Spectrum Disorder
Participation-based Intervention on Community Participation and Parent Empowerment for Children With ASD
Community participation of children with ASD is affected by child (including body function and personal factors), family and environmental factors.
- Trial name
- PBI-ASD (NCT03721913)
- Testing
- participation-based intervention
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Chang Gung University
Autism Spectrum Disorders, Psychosis
Brain Connectivity in Neurodevelopmental Disorders in Response to Treatment
The purpose of the proposed research is to study the potential changes in biomarkers of patients with neurodevelopmental disorders in response to treatment in clinical trials or in private psychiatry practice utilizing…
- Conditions
- Autism Spectrum Disorders, Psychosis, Fragile X Syndrome
- Trial name
- NCT01364818
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of North Carolina, Chapel Hill
Autism, Aggression
The Family VOICE Study
Family centered mental health treatment with children values and supports the role of parents in their child's recovery. However, medications are often the primary focus in community treatment, even in preschool age youth, with…
- Conditions
- Autism, Aggression, Bipolar Disorder, Psychotic Disorders
- Trial name
- NCT01804582
- Testing
- Family Navigator consultation
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- University of Maryland, Baltimore