Clinical trials: Autism Spectrum Disorders (ASD), active
Autism, Autism Spectrum Disorder
Trial of Center-Based vs. In-Home Pivotal Response Treatment (PRT) in Autism
The aim of this clinical trial is to compare the efficacy of a 16-week center-based Pivotal Response Treatment (PRT-C) versus home-based Pivotal Response Treatment (PRT-H) in targeting social communication deficits in young…
- Conditions
- Autism, Autism Spectrum Disorder, ASD
- Trial name
- PRT-HvC (NCT04899544)
- Testing
- Center-Based Pivotal Response Treatment (PRT) Intervention (PRT-C), Home-Based Pivotal Response Treatment (PRT Intervention (PRT-H)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Stanford University
Autism Spectrum Disorder (ASD), Autism
Trial of Center-Based Early Start Denver Model vs. Pivotal Response Treatment in Children With Autism
The goal of this study is to compare two well-established early autism interventions, Early Start Denver Model (ESDM) and Pivotal Response Treatment (PRT), to better understand which approach is most effective for improving…
- Trial name
- NCT07522190
- Testing
- Early Start Denver Model (ESDM), Pivotal Response Treatment (PRT), Developmental Reciprocity Treatment (DRT)
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Stanford University
Autism Spectrum Disorder (ASD)
An Empowering Parent Training Intervention to Increase Physical Activity in Preschool Aged Children With Autism
The goal of this clinical trial is to learn if WE PLAY for Parents can improve caregivers' knowledge, attitudes, confidence, and skills promoting physical activity with their young child with autism.
- Trial name
- NCT07421830
- Testing
- Wellness Enhancing Physical Activity for Young Children: Parent Version (WE PLAY for Parents)
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Autism Spectrum Disorder (ASD
Effectiveness of Clown Therapy in Facilitating Dental Visits for Children With Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by difficulties in verbal and non-verbal communication and social interaction, as well as repetitive and stereotyped behaviors.
- Trial name
- NCT07906288
- Testing
- Familiarization sessions using clown therapy, Familiarization sessions with conventional methods
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- University of Milan
Neurodevelopmental Disorders, Autism Spectrum Disorder (ASD)
Single Session Support for Parents of Children With Neurodevelopmental Disabilities Struggling With Anxious Avoidance
This study will inform the development of a brief online program to help parents better understand and respond to anxiety-related behaviors in children with neurodevelopmental disorders (NDDs) such as autism spectrum disorder…
- Conditions
- Neurodevelopmental Disorders, Autism Spectrum Disorder (ASD), Attention-Deficit/Hyperactivity Disorder (ADHD), Intellectual Disability
- Trial name
- EMPOWER-ND (NCT07898592)
- Testing
- EMPOWER-ND
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston University Charles River Campus
Autism Spectrum Disorder, Autism Spectrum Disorder (ASD
Evaluation of a Novel Quantum-Inspired Intervention (QII) for Children With Autism Spectrum Disorder: A Global Confirmatory Study
The purpose of this global multicenter confirmatory study is to evaluate the clinical efficacy and safety of Quantum-Inspired Intervention (QII), a novel non-invasive neurodevelopmental protocol, in children diagnosed with Autism…
- Conditions
- Autism Spectrum Disorder, Autism Spectrum Disorder (ASD, ASD
- Trial name
- NCT07898787
- Testing
- Quantum-Inspired Intervention (QII)
- Volunteers
- 80 people
- Sponsor
- BlissBot, Inc
Autism Spectrum Disorder (ASD
EEG As a Genetic Selection Lever in Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is a growing public health concern, with genetic causes identified in about 20% of cases. While exome/genome sequencing is powerful, its cost and limited yield call for better patient selection.
- Trial name
- EAGLE (NCT07891065)
- Testing
- Collection of routine care data
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Autism Spectrum Disorder (ASD)
Coaching and Leadership in Autism Support Settings
Schools serve a large number of autistic children, yet face two critical gaps that stifle the delivery of evidence-based practices: 1) an intervention gap characterized by limited availability of evidence-based practices…
- Trial name
- CLASS (NCT07276750)
- Testing
- RUBIES, HELM, Educator Psychoeducation
- Where
- United States
- Volunteers
- 373 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Attention Deficit Disorder With Hyperactivity (ADHD), Autism Spectrum Disorder (ASD)
External Trigeminal Nerve Stimulation for Children With ASD + ADHD to Reduce Elevated Symptoms
The goal of this clinical trial is to learn if external trigeminal nerve stimulation (eTNS) works to treat ADHD symptoms in children on the autism spectrum (ASD).
- Trial name
- eTNS CARES (NCT07214545)
- Testing
- Trigeminal Nerve Stimulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Autism Spectrum Disorder (ASD
Monitoring Daily Mobility in Children With Autism
Children with autism spectrum disorder (ASD) often show motor abnormalities and sleep disturbances that affect behavior, learning, and family quality of life.
- Trial name
- SIMBA (NCT07519369)
- Testing
- placement of a wearable wrist sensor
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Autism Spectrum Disorder (ASD)
Expression Intensity Modulates Social Intention Understanding in ASD Children
Children watch videos of a single model playing with toys, judge whether the model desires a new toy based on observing the model's varying expression intensities, and form a judgment on whether the model intends to obtain a new…
- Trial name
- NCT07884032
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Autism Spectrum Disorder (ASD), Anxiety
Adapted Group Therapy Compared With Usual Care for Anxiety and Depression in Adults With an Autism Diagnosis
The goal of this clinical trial is to learn whether an adapted group therapy works to treat anxiety and depression in adults with an autism diagnosis. The therapy is a form of cognitive behavioral therapy (CBT).
- Conditions
- Autism Spectrum Disorder (ASD), Anxiety, Depression
- Trial name
- CoMind (NCT07880028)
- Testing
- Autism-adapted group cognitive behavioral therapy
- Volunteers
- 154 people
- Sponsor
- Lovisenberg Diakonale Hospital
Schizophrenia / Schizoaffective Disorder, First Episode Psychosis (FEP)
French Minds Cohort: a French Longitudinal and Multimodal Cohort of Patients With Major Mood Disorders, Psychotic Disorders, Autism Spectrum Disorders, and Healthy Controls
The goal of this study is to learn whether people living with severe psychiatric disorders can be grouped into more homogeneous subgroups, across usual diagnostic categories, based on two key dimensions: social withdrawal and…
- Conditions
- Schizophrenia / Schizoaffective Disorder, First Episode Psychosis (FEP), Bipolar Disorder (BD), Major Depressive Disorder (MDD
- Trial name
- FRENCH-MINDS (NCT07881016)
- Testing
- 3T Brain MRI, Biological Sampling, Clinical, Cognitive and Digital Assessments
- Where
- 17 sites in France
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Fondation FondaMental
Autism Spectrum Disorder (ASD, Prospective Study
Prospective Clinical Study on Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes for the Treatment of Childhood Autism
This clinical study aims to evaluate whether a nasal spray containing exosomes derived from human umbilical cord mesenchymal stem cells (hUC-MSC-EXOs) can safely and effectively improve core symptoms in children aged 3-7 years…
- Trial name
- EXO-ASD (NCT07243561)
- Testing
- hUC-MSC-Exos Nasal Spray
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Dongfang People's Hospital
Autism Spectrum Disorder (ASD), Motivation
Motivation for Daily Living Skills
The goal of this clinical trial is to enhance motivation to complete daily living skills among 16 to 25-year-old autistic teens and young adults.
- Trial name
- NCT07159308
- Testing
- Intrinsic Motivation Treatment, Extrinsic Motivation Treatment, Combined Intrinsic and Extrinsic Motivation Treatment
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Children's Hospital of Philadelphia
Fragile X Syndrome (FXS), Autism Spectrum Disorder (ASD)
A Study to Investigate the Effects and Safety of Codabakalner for the Treatment of FXS in Male Participants and Adult Participants With ADS
This is a Study to Investigate the Effects and Safety of Codabakalner for the Treatment of Fragile X Syndrome in Male Participants and Adult Participants with Autism Spectrum Disorders
- Trial name
- NCT07439510
- Testing
- Codabakalner
- Volunteers
- 120 people
- Sponsor
- Spinogenix
Autism Disorder, Autism Spectrum Disorder (ASD
Effectiveness of Interactive Techniques on Oral Hygiene Skills in a Group of Autistic Egyptian Children
The present study will be performed to evaluate the effectiveness of peer modeling and audiovisual peer modeling video on toothbrushing skills in comparison to the visual pedagogical method at home.
- Conditions
- Autism Disorder, Autism Spectrum Disorder (ASD, Autism, Plaque Reduction
- Trial name
- Autism ASD (NCT07859696)
- Testing
- Peer model, Pre-recorded video of peer modeling, Pedagogical method
- Volunteers
- 90 people
- Sponsor
- Faculty of Dental Medicine for Girls
Autism Spectrum Disorder (ASD), Transcranial Direct Current Stimulation (tDCS)
Resting-State Functional Connectivity as a Predictor of tDCS Effects in Adolescents With Autism Spectrum Disorder
Background: Transcranial Direct Current Stimulation (tDCS) is a form of non-invasive brain stimulation that has aroused increased interests in the past decade.
- Conditions
- Autism Spectrum Disorder (ASD), Transcranial Direct Current Stimulation (tDCS), Electroencephalography
- Trial name
- NCT06878326
- Testing
- tDCS
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Autism Spectrum Disorder (ASD)
Neuromotor Task Training in Autistic Children With Motor Difficulties
The goal of this clinical study is to learn whether Neuromotor Task Training (NTT) may help improve functional motor skills in autistic children who have motor difficulties.
- Trial name
- NTT-SCED (NCT07797439)
- Testing
- Neuromotor Task Training
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Groupe Hospitalier Nord-Essonne
Autism Spectrum Disorder, Autism
Adia Med of Winter Park LLC Autism Spectrum Disorder Research Study
This 12-month study tests whether AdiaVita (umbilical cord blood-derived stem cells and exosomes) plus glutathione improves autism symptoms more than glutathione alone in children ages 3-12.
- Conditions
- Autism Spectrum Disorder, Autism, ASD, Autism Spectrum Disorder (ASD)
- Trial name
- NCT07304440
- Testing
- Umbilical Cord Blood-Derived Stem Cells and Exosomes, Glutathione
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Adia Med of Winter Park LLC