Clinical trials: Autistic Behavior
Autism
Combined Effects of Early Behavioral Intervention and Propranolol on ASD
The purpose of this study is to explore the effects of propranolol in combination with early intensive behavioral intervention on social interaction, and secondarily on language, anxiety, adaptive behaviors, and global function…
- Trial name
- NCT02428205
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Missouri-Columbia
Autism Spectrum Disorder
Behavioral and Neural Response to Memantine in Adolescents With Autism Spectrum Disorder
This study is a 12-week, randomized-controlled trial of memantine hydrochloride (Namenda) for the treatment of social impairment in adolescents with autism spectrum disorder (ASD).
- Trial name
- NCT01972074
- Testing
- Memantine
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder, Asperger Disorder
Neurocircuitry of Autism- fMRI and Transcranial Magnetic Stimulation Studies
This study uses functional brain imaging and noninvasive brain stimulation techniques to study the brain basis of developmental disorders like Autism Spectrum Disorder and Asperger Disorder.
- Conditions
- Autism Spectrum Disorder, Asperger Disorder, Pervasive Developmental Disorder
- Trial name
- NCT01553240
- Testing
- TMS and functional MRI (Magstim)
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Autism Spectrum Disorder
Preliminary Efficacy of Occupational Therapy Integrating Horses on Self-regulation in Youth With Autism
The goal of this clinical trial is to learn about occupational therapy integrating horses for autistic youth. The main questions it aims to answer are: Does occupational therapy integrating horses improve self-regulation in…
- Trial name
- NCT05846932
- Testing
- OTEE HORS, OT Clinic
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Autism
Learning Enhancement Through Neurostimulation in Autism
This study will examine whether brain stimulation paired with social skills learning can help teenage boys with autism learn how to make and keep friends. Brain stimulation can enhance learning in some people.
- Trial name
- LENS (NCT02998684)
- Testing
- Active Transcranial Direct Current Stimulation, PEERS Social Skills Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Autism, Pervasive Developmental Disorder
Evaluation and Treatment of Copper/Zinc Imbalance in Children With Autism
There are two phases to the study. The first will examine serum copper and zinc levels and copper/zinc ratio in children (ages 3-8) who have autism and compare them to levels from same sex and age children who are developing…
- Trial name
- NCT00325572
- Testing
- oral zinc and vitamin C supplements
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Autism Spectrum Disorders
Study of Oxytocin in Autism to Improve Reciprocal Social Behaviors
The purpose of this research study is to learn about the effects of supplemental intranasal oxytocin as a treatment for improving social difficulties in children and adolescents with autism.
- Trial name
- SOARS-B (NCT01944046)
- Testing
- double Blind Oxytocin Nasal Spray, Open Label intranasal oxytocin
- Where
- 7 sites in United States
- Volunteers
- 290 people
- Sponsor
- Linmarie Sikich
Autism Spectrum Disorders
Gaming for Autism to Mold Executive Skills Project
The goal of the project is to better understand executive control-how children manage complex or conflicting information in the service of a goal.
- Trial name
- GAMES (NCT02361762)
- Testing
- Computerized executive control training
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Boston Children's Hospital
Autism Spectrum Disorder, Mental Disorders
Physiological Mechanisms of Therapeutic Horseback Riding Intervention Effects in a Psychiatric Population of ASD Youth
This randomized control trial (RCT) seeks to assess the mechanisms underlying Therapeutic Horseback Riding's (THR) previously observed significant positive effects on ASD youth, particularly those with co-occurring psychiatric…
- Trial name
- NCT04606966
- Testing
- Therapeutic Horseback Riding, Barn Activity, Hybrid
- Where
- 2 sites in United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Attention-deficit/Hyperactivity Disorder, Autism Spectrum Disorder
Methylphenidate ER Liquid Formulation in Adults With ASD and ADHD
The purpose of this study is to determine whether methylphenidate hydrochloride extended release liquid formulation is safe and effective in the treatment of attention-deficit/hyperactivity disorder (ADHD) in high-functioning…
- Trial name
- NCT02096952
- Testing
- Methylphenidate extended-release liquid formulation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder, Aggression
Nicotinic Cholinergic Modulation as a Novel Treatment Strategy for Aggression Associated With Autism
Some individuals with autism spectrum disorders (ASD) also demonstrate irritability or aggression, which can interfere with functioning.
- Conditions
- Autism Spectrum Disorder, Aggression, Irritability
- Trial name
- NCT02552147
- Testing
- Transdermal nicotine
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Yale University
Autism, Attention Deficit Disorder With Hyperactivity
Methylphenidate for Attention Deficit Hyperactivity Disorder and Autism in Children
This study examined the cognitive and behavioral differences in children who have an autism spectrum disorder (ASD) with or without additional symptoms of ADHD.
- Trial name
- NCT00178503
- Testing
- Methylphenidate-extended release, Methylphenidate-immediate release
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Autism Spectrum Disorder
Enhancing Social Competence in Adults With Autism
SENSE Theatre®, combines several well-documented, effective behavioral strategies, such as the inclusion of trained peer models, theatre play techniques involving predictable (i.e., scripted) and flexible (improvised) role-play…
- Trial name
- NCT04349644
- Testing
- SENSE Theatre
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Vanderbilt University Medical Center
Autism Spectrum Disorder
Fatty Acid Supplementation in Children With ASD (Study 2)
The objective of the protocol is to test the impact of Omega 3-6 on pre-specified biological signatures (IL-1β, IL-2, and IFNγ) and to correlate changes in the biological signatures with changes in ASD symptoms.
- Trial name
- NCT04312932
- Testing
- LCPUFA Oil Supplement
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Sarah Keim
Autism Spectrum Disorders
Mirtazapine Treatment of Anxiety in Children and Adolescents With Pervasive Developmental Disorders
This study will determine the effectiveness of mirtazapine in reducing anxiety in children with autistic disorder, Asperger's disorder and Pervasive Developmental Disorder.
- Trial name
- NCT01302964
- Testing
- Mirtazapine
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Autistic Disorder, Autism
Withdrawal Study of Memantine in Pediatric Patients With Autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified Previously Treated With Memantine
The purpose of this randomized withdrawal study is to evaluate the safety, tolerability, and efficacy of memantine compared with placebo in pediatric patients with autism, Asperger's Disorder, or Pervasive Developmental Disorder…
- Conditions
- Autistic Disorder, Autism, Asperger's Disorder, Asperger Syndrome
- Trial name
- NCT01592747
- Testing
- Memantine Hydrochloride (HCl)
- Where
- 94 sites in United States, Belgium and 13 more
- Volunteers
- 479 people
- Sponsor
- Forest Laboratories
Autism Spectrum Disorder
Reducing Challenging Behaviors in Children With Autism Through Digital Health
School-based behavioral approaches to managing challenging behaviors in children with ASD are limited by three key factors: 1) children with ASD often have difficulties communicating their emotions; 2) it is challenging to…
- Trial name
- NCT05277194
- Testing
- KeepCalm app
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of Pennsylvania
Autism Spectrum Disorder, Intellectual Disability
Expert Guiding Technology to Help Individuals With Developmental Challenges Build Life and Vocational Skills
Clinical trials will evaluate the efficacy of expert guiding technology to support instructors to better help individuals with developmental challenges due to ASD and ID learn life and vocational skills.
- Trial name
- NCT04518358
- Testing
- Use of Expert Guiding Technology (GAINS) to Improve Live and Vocational Skills for Individuals with Developmental Challenges
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- John T. Nosek
Autistic Disorder, Asperger's Disorder
D-Cycloserine and Social Skills Training in Autism Spectrum Disorders
The purpose of this study is to determine the effectiveness of D-cycloserine for improving social impairment in child with pervasive developmental disorders (PDD).
- Conditions
- Autistic Disorder, Asperger's Disorder, Pervasive Developmental Disorder NOS
- Trial name
- NCT01086475
- Testing
- D-cycloserine
- Where
- 2 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Indiana University
Autistic Disorder
Study of Aripiprazole in the Treatment of Children and Adolescents With Autistic Disorder (AD).
This study will compare the effectiveness (how well the drug works) of aripiprazole, flexibly dosed with a placebo, in reducing serious behavioral problems in children and adolescents with a diagnosis of autistic disorder (AD).
- Trial name
- NCT00332241
- Testing
- Aripiprazole
- Where
- 9 sites in United States
- Volunteers
- 98 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.