Clinical trials: Autistic Spectrum Disorder
Autism, Autism Spectrum Disorder
Autism Oxytocin Brain Project
The main goal of the study is to look at the effects of intranasal oxytocin on the brain in Autism Spectrum Disorder (ASD). Oxytocin is a hormone that exists naturally in the body and the brain, affecting a wide range of social…
- Trial name
- NCT03033784
- Testing
- 8 International Units (IU) of Oxytocin, 24IU of Oxytocin, 48IU of Oxytocin
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Emory University
Autism Spectrum Disorder, Autism
Allogenic Cord Blood Transfusion in Patients With Autism
Autism is one of those disorders in Autism spectrum disorders (ASD), which characterized by social interaction abnormalities, impaired verbal and non-verbal communication, and repetitive, obsessive behavior, while the therapeutic…
- Trial name
- NCT03786744
- Testing
- ASD CB-MNC injection., Standard therapy.
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- State-Financed Health Facility "Samara Regional Medical Center Dinasty"
Autism Spectrum Disorders, Normal Hearing
The Effects of ProFoveate on Reducing Self-Stimulating Behaviors
This study is designed to pilot an intervention technique to reduce the self-stimulating behaviors seen in individuals with autism spectrum disorders using intervention with ProFoveate pellets.
- Conditions
- Autism Spectrum Disorders, Normal Hearing, Normal Intelligence, Exhibit Self- Stimulating or Ritualistic Behaviors
- Trial name
- NCT02088047
- Testing
- ProFoveate
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Autism Spectrum Disorder, Autism
The Effect of Korean Version of PEERS Social Skills Training for Young Adults (PEERS-YA-K) With Autism Spectrum Disorder
Despite the psychosocial difficulties common among young adults with autism spectrum disorders(ASD), little to no evidence-based social skills interventions exist for this population.
- Trial name
- NCT03310775
- Testing
- Parent-assisted social skills training program for young adult with ASD
- Volunteers
- 47 people
- Sponsor
- Seoul National University Hospital
Autism Spectrum Disorder, ASD
Cord Blood Infusion for Children With Autism Spectrum Disorder
This is a single site, prospective, randomized, double-blind study of a single intravenous autologous or allogeneic, unrelated cord blood (CB) infusion in children ages 2-7 years with Autism Spectrum Disorder (ASD).
- Conditions
- Autism Spectrum Disorder, ASD, Autism, PDD
- Trial name
- Duke ACT (NCT02847182)
- Testing
- Cord Blood Infusion
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Joanne Kurtzberg, MD
Autism Spectrum Disorder, Autistic Disorder
Sulforaphane for the Treatment of Young Men With Autism Spectrum Disorder
The aim of this randomized controlled trial is to determine if a nutritional supplement containing broccoli sprout and seed extracts, a rich source of sulforaphane, is effective in reducing core symptoms of autism spectrum…
- Conditions
- Autism Spectrum Disorder, Autistic Disorder, Neurodevelopmental Disorder, Childhood Developmental Disorders, Pervasive
- Trial name
- NCT02909959
- Testing
- Sulforaphane
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of North Carolina, Chapel Hill
Autism Spectrum Disorder
Extension for Community Healthcare Outcomes Autism Replication Evaluation
ECHO Autism was intended to assess rigorously the impact of a 12-session telemedicine training program on participating Primary Care Providers (PCP) knowledge, clinical behavior, and self-efficacy in the screening and care of…
- Trial name
- ECHO Autism (NCT03677089)
- Testing
- 12 ECHO Autism telehealth clinics
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorders
Intranasal Oxytocin for the Treatment of Autism Spectrum Disorders
Autism Spectrum Disorder (ASD) is a developmental disorder characterized by abnormalities in speech and communication, impaired social functioning and repetitive behaviors and restricted interests.
- Trial name
- INOT (NCT01337687)
- Testing
- Intranasal Oxytocin
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Montefiore Medical Center
Autism Spectrum Disorder, Asperger Syndrome
Milnacipran in Autism and the Functional Locus Coeruleus and Noradrenergic Model of Autism
Autism Spectrum Disorders (ASD) include Autistic disorder, Asperger's syndrome and Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS). These are developmental disorders beginning prior to three years of age.
- Conditions
- Autism Spectrum Disorder, Asperger Syndrome, Aspergers Syndrome
- Trial name
- NCT01337700
- Testing
- Milnacipran
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Montefiore Medical Center
Autism, Autism Spectrum Disorder
Intensive Intervention for Toddlers With Autism (EARLY STEPS)
Goals of the current project: (1) Does the Early Start Denver Model experimental intervention for toddlers with autism reduce disability associated with autism significantly more than standard community interventions?; and (2)…
- Trial name
- NCT00698997
- Testing
- Early Start Denver Model, Standard community care
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of California, Davis
Autistic Disorder, Autism Spectrum Disorder
Training Attention and Eye Movement in ASD
Current therapies for autism target social and language behaviors, but due to the high-level nature of these skills any improvement rarely extends beyond the targeted behavior.
- Trial name
- NCT02403817
- Testing
- Cognitive Training, Eye Motor Training, Hand Motor Training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Diego
Autism Spectrum Disorder, Depression
TMS for Adults With Autism and Depression
The goal of this proposal is to investigate whether a standard rTMS protocol for depression, including multiple sessions applied to left dorsolateral prefrontal cortex (DLPFC) results in reduction of depressive symptoms for adult…
- Conditions
- Autism Spectrum Disorder, Depression, Depressive Disorder, Major Depressive Disorder
- Trial name
- TAD (NCT02939560)
- Testing
- NeuroStar® TMS device (Neuronetics, Atlanta, GA)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Autistic Disorder, Autism
Withdrawal Study of Memantine in Pediatric Patients With Autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified Previously Treated With Memantine
The purpose of this randomized withdrawal study is to evaluate the safety, tolerability, and efficacy of memantine compared with placebo in pediatric patients with autism, Asperger's Disorder, or Pervasive Developmental Disorder…
- Conditions
- Autistic Disorder, Autism, Asperger's Disorder, Asperger Syndrome
- Trial name
- NCT01592747
- Testing
- Memantine Hydrochloride (HCl)
- Where
- 94 sites in United States, Belgium and 13 more
- Volunteers
- 479 people
- Sponsor
- Forest Laboratories
Autism Spectrum Disorders
Mirtazapine Treatment of Anxiety in Children and Adolescents With Pervasive Developmental Disorders
This study will determine the effectiveness of mirtazapine in reducing anxiety in children with autistic disorder, Asperger's disorder and Pervasive Developmental Disorder.
- Trial name
- NCT01302964
- Testing
- Mirtazapine
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorders
Examining the Efficacy of Mattress Technology in Improving the Sleep Quality of Children With ASD
The purpose of the present study is to evaluate the tolerability and efficacy of the Sound To Sleep System™ in improving the sleep quality of children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT02739321
- Testing
- Sound to Sleep System
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The Cleveland Clinic
Autism Spectrum Disorder, Autistic Disorder
A Folinic Acid Intervention for Autism Spectrum Disorders
Researchers at Arkansas Children's Hospital Research Institute are conducting a study looking at the effects of Folinic Acid on language in Autism Spectrum Disorder and language impairment. The study has 3 phases.
- Conditions
- Autism Spectrum Disorder, Autistic Disorder, Autism, Asperger's Syndrome
- Trial name
- NCT01602016
- Testing
- Folinic Acid
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Arkansas
Autism Spectrum Disorders
A Trial of the Drug Donepezil for Sleep Enhancement and Behavioral Change in Children With Autism
Background: Some children with autism spectrum disorders (ASD) do not have normal sleep cycles. Some of these children spend very little time in the rapid eye movement (REM) stage of sleep.
- Trial name
- NCT01887132
- Testing
- Donepezil
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Institute of Mental Health (NIMH)
Autistic Disorder, Asperger Syndrome
A Study of Oral N-Acetylcysteine in Children With Autism Spectrum Disorders
The purpose of this study is to determine whether treatment with oral N-acetylcysteine (NAC) will improve behavior problems often associated with autism spectrum disorders.
- Conditions
- Autistic Disorder, Asperger Syndrome, Child Development Disorders, Pervasive
- Trial name
- NCT00453180
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Indiana University
Autistic Disorder, Asperger's Disorder
D-Cycloserine and Social Skills Training in Autism Spectrum Disorders
The purpose of this study is to determine the effectiveness of D-cycloserine for improving social impairment in child with pervasive developmental disorders (PDD).
- Conditions
- Autistic Disorder, Asperger's Disorder, Pervasive Developmental Disorder NOS
- Trial name
- NCT01086475
- Testing
- D-cycloserine
- Where
- 2 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Indiana University
Autism
Intranasal Oxytocin in the Treatment of Autism
The purpose of this study is to learn whether or not the drug called oxytocin is helpful in improving mood and social functioning in adults with autism.
- Trial name
- NCT00490802
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Evdokia Anagnostou