Clinical trials: Autistic Spectrum Disorders
Autism Spectrum Disorder, Autism
Vancomycin and Fecal Microbiota Transplant in a Single Patient With Autism Spectrum Disorder
Single patient with ASD will be treated with Vancomycin followed by FMT.
- Trial name
- NCT04878718
- Testing
- Fecal Microbiota Transplant; Vancomycin
- Where
- United States
- Sponsor
- ProgenaBiome
Autism Spectrum Disorder, Autistic Disorder
A Folinic Acid Intervention for Autism Spectrum Disorders
Researchers at Arkansas Children's Hospital Research Institute are conducting a study looking at the effects of Folinic Acid on language in Autism Spectrum Disorder and language impairment. The study has 3 phases.
- Conditions
- Autism Spectrum Disorder, Autistic Disorder, Autism, Asperger's Syndrome
- Trial name
- NCT01602016
- Testing
- Folinic Acid
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Arkansas
Autism Spectrum Disorder
Parent-mediated Developmental Behavioral Intervention
This study explores the effectiveness of two intervention programs: "Long-distance developmental behavioral intervention" and "developmental behavioral interventions" for children with autism spectrum disorder or multiple…
- Trial name
- PDBI (NCT03812068)
- Testing
- Long-distance developmental behavioral intervention, Developmental behavioral intervention
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder
The Effectiveness of Group Interpersonal Synchrony in Young Autistic Adults' Work Environment
Background: Few autistic adults are able to integrate successfully into the world of work given their difficulties adapting to the social and stressful aspects of work environments.
- Trial name
- NCT05846308
- Testing
- Structured synchronous physical training, Structured non-synchronous physical training
- Where
- Israel
- Volunteers
- 57 people
- Sponsor
- University of Haifa
Autism Spectrum Disorder (ASD), Intellectual Disability
Emotion Intensity Modulates Intention in ASD
This study used eye-tracking to examine how emotional expression intensity (low/medium/high) influences intention understanding in children with ASD, PDD, and TD during a puzzle-search task.
- Trial name
- NCT07597655
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Fragile X Syndrome
A Safety Study of NNZ-2566 in Patients With Fragile X Syndrome
The purpose of this study is to determine whether NNZ-2566 is safe and well tolerated in the treatment of Fragile X Syndrome in adolescent and adult males.
- Trial name
- NCT01894958
- Testing
- NNZ-2566
- Where
- 17 sites in United States
- Volunteers
- 72 people
- Sponsor
- Neuren Pharmaceuticals Limited
Autism
Pharmacogenomics in Autism Treatment
Autism is a complex neurodevelopmental disorder that is thought to involve an interaction between multiple and variable susceptibility genes, environmental factors, and epigenetic effects.
- Trial name
- PG (NCT00584701)
- Testing
- Risperidone
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of California, San Francisco
Autism Spectrum Disorder
Microbiome and Mycobiome Registry of Volunteers With and Without Autism Spectrum Disorder
Analyze, describe, and understand how the human gut microbiome (i.e. bacteriome and mycobiome) and Autism Spectrum Disorder (ASD) are related.
- Trial name
- NCT03819439
- Testing
- Microbiome and Autism Questionnaire
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Autism
Lurasidone Pediatric Autism Study
This is a randomized, double-blind, placebo-controlled study designed to evaluate the efficacy and safety of 2 fixed doses of lurasidone (20 mg/day and 60 mg/day) for 6 weeks compared with placebo in pediatric and adolescent…
- Trial name
- NCT01911442
- Testing
- Lurasidone 20 mg daily, Lurasidone
- Where
- 41 sites in United States
- Volunteers
- 150 people
- Sponsor
- Sumitomo Pharma America, Inc.
Autism Spectrum Disorder, Schizotypal Disorder
The Development of a Screening Questionnaire to Discriminate Autism Spectrum Disorder and Schizotypal Disorder, and Validation of the Danish Version of RAADS-R
The aim of the study is to investigate the validity, reliability and clinical features of a Danish version of the Ritvo Autism Asperger Diagnostic Scale-Revised (RAADS-R).
- Trial name
- ZA-RAA (NCT05213286)
- Testing
- Application of ZAQ and RAADS-R-DK
- Where
- Denmark
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Autism Spectrum Disorder
Modulating Socially Adaptive Mirror System Functioning in Autism by Oxytocin
This study investigates the efficacy of a single-dose of exogenous oxytocin administration on socially adaptive mirror-motor mapping in participants with Autism Spectrum Disorders.
- Trial name
- NCT03640156
- Testing
- Oxytocin
- Where
- Belgium
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Autism, Depressed
Behavioral Activation for Treatment of Depression in Autistic Adolescents With Below Average Intelligence
Autism spectrum disorder is characterized by differences in social communication/interaction and the presence of restricted/repetitive behaviors, with significant heterogeneity in terms of autistic features, language ability, and…
- Conditions
- Autism, Depressed, Depressed Mood
- Trial name
- NCT07812870
- Testing
- BA-A
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Stony Brook University
Autism
Efficacy and Safety of Trichuris Suis Ova (TSO) as Compared to Placebo in Autism Spectrum Disorder
This is a randomized, double-blind, 2-arm, placebo-controlled crossover study in pediatric patients with autism spectrum disorder with all patients receiving 16-weeks of TSO treatment and 16 weeks of placebo.
- Trial name
- NCT02140112
- Testing
- Trichuris suis ova
- Where
- 5 sites in United States
- Volunteers
- 23 people
- Sponsor
- Coronado Biosciences, Inc.
Autism Spectrum Disorder (ASD
Effectiveness of DIR/Floortime™ in Children With Autism Spectrum Disorder
This randomized controlled trial evaluates the efficacy of Integrated DIR/Floortime™ in improving functional emotional development and adaptive behavior in children aged 4-12 years with Autism Spectrum Disorder (ASD).
- Trial name
- DIR-ASD (NCT07758465)
- Testing
- DIR/Floortime, Standard therapy
- Where
- Pakistan
- Volunteers
- 14 people
- Sponsor
- Fatima Tabassum
Autism Spectrum Disorder, Other Neurodevelopmental Disorder
Early Assessment of Autism Through Smart Tablet Gameplay
The primary aim of this study is to compare the diagnostic accuracy of an iPad application (Play.Care assessment) with the current clinical "gold standard" diagnosis for diagnosis of Autism Spectrum Disorder (ASD) in children.
- Trial name
- NCT03438994
- Testing
- Play.Care
- Where
- 2 sites in Sweden, United Kingdom
- Volunteers
- 779 people, healthy volunteers welcome
- Sponsor
- University of Strathclyde
Global Developmental Delay, Cerebral Palsy
Predicting Developmental Disability Type and Mental Retardation Level in Children With General Developmental Delay
The purpose of this study is to find the relationship between the stage and quality of developmental delay during infancy and toddler age, and the final diagnosis that the child gets a few years later (MR, type of PDD, CP or…
- Conditions
- Global Developmental Delay, Cerebral Palsy, Mental Retardation, Pervasive Developmental Disorders
- Trial name
- NCT01430845
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Sheba Medical Center
Autism Spectrum Disorder, Sulforaphane
Mechanism Study of Sulforaphane in ASD Improvement
The goal of this clinical trial is to find out if sulforaphane (SFN) can improve social skills and behavior in people with Autism Spectrum Disorder (ASD).
- Trial name
- ASD (NCT07047976)
- Testing
- Sulforaphane
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Jian-Jun Ou
Autism Spectrum Disorder
Comparison of DSM-IV-TR and DSM-5 for ASD
The study aim is to prospectively compare DSM-IV-TR and DSM-5 criteria for Autism Spectrum Disorder (ASD) in a sample of 250 children and adolescents who meet DSM-IV-TR criteria for ASD and 150 children and adolescents referred…
- Trial name
- NCT02296502
- Testing
- DSM
- Where
- 5 sites in United States
- Volunteers
- 439 people
- Sponsor
- University of Pittsburgh
Developmental Disability, Intellectual Disability
Validation of Optical Genome Mapping for the Identification of Constitutional Genomic Variants in a Postnatal Cohort
The purpose of this research use only (RUO) study is to detect genomic structural variants (SVs) in human DNA by Optical Genome Mapping (OGM) using the Bionano Genomics Saphyr system.
- Conditions
- Developmental Disability, Intellectual Disability, Autism Spectrum Disorder, Congenital Anomaly
- Trial name
- NCT05295277
- Testing
- Standard of care genetic testing group
- Where
- 8 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Bionano Genomics
Autism, Fragile-X Syndrome (FXS)
Glutaminergic Transmission in Autism : Molecular Imaging Exploration
Glutamatergic transmission exploration using PET (Positron Emission Tomography) imaging in autism compared to Fragile-X Syndrome ( FXS) and Healthy Volunteers
- Conditions
- Autism, Fragile-X Syndrome (FXS), Healthy Volunteers
- Trial name
- TANGAU (NCT02719951)
- Testing
- [18F]FPEB PET imaging, Biological samples, MRI
- Where
- France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours