Clinical trials: Autobiographical Memory
Psychosis
The Relationship Between Autobiographical Memory and Motivation
People with a diagnosis of psychosis often experience low motivation and pleasure when thinking about doing future activities. This leads, quite understandably, to doing fewer activities they used to enjoy and not taking up…
- Trial name
- NCT03677635
- Testing
- Guided Autobiographical Memory Recall
- Where
- 2 sites in United Kingdom
- Volunteers
- 31 people
- Sponsor
- King's College London
Schizophrenia
rTMS as a Probe of Episodic Memory Neurocircuitry in Schizophrenia
This will be a single site pilot study. 30 subjects with Early Phase Psychosis (EPP), defined as medical record documentation of the onset of clinically significant psychotic symptoms within the past ten years, will be enrolled.
- Trial name
- rTMS-EM (NCT04182113)
- Testing
- 1 Hz rTMS Stimulation
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Indiana University
Depression
Enhancing the Effectiveness of Electroconvulsive Therapy in Severe Depression
Electroconvulsive therapy (ECT) is the most powerful antidepressant treatment available and is often life-saving. There are concerns, however, that standard bitemporal ECT (the most commonly used form of ECT worldwide) causes…
- Trial name
- EFFECT-Dep (NCT01907217)
- Testing
- ECT Mecta 5000M, Methohexitone, Suxamethonium
- Where
- Ireland
- Volunteers
- 138 people
- Sponsor
- St Patrick's Hospital, Ireland
Normal Physiology
Task-dependent Effects of TMS on the Neural Biomarkers of Episodic Memory
Background: Transcranial magnetic stimulation (TMS) of the brain has been used to change the activity and connections in the brain to improve memory.
- Trial name
- NCT04694131
- Testing
- TMS
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Motivation
InformationSeekingMesolimbicEngagementStudy1
Study 1 will use a novel Game Show task, in which the investigators manipulate participant's agency to control their learning environment to specify unguided exploration.
- Trial name
- NCT06257446
- Testing
- Task Instructions
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Temple University
Amnestic Mild Cognitive Impairment, Traumatic Brain Injury
Noninvasive Brain Stimulation on Memory in Individuals With Mild Cognitive Impairment and History of Brain Injury
The study will examine the efficacy of high definition transcranial direct current stimulation (HD-tDCS) and its influence on episodic memory in patients with amnestic mild cognitive impairment and a history of Traumatic brain…
- Conditions
- Amnestic Mild Cognitive Impairment, Traumatic Brain Injury, Mild Traumatic Brain Injury
- Trial name
- NCT04504630
- Testing
- High Definition Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Texas Southwestern Medical Center
Down Syndrome, Intellectual Disability
Down Syndrome Memantine Follow-up Study
The purpose of this research study is to learn if the medication Memantine Hydrochloride (the study medication) can help adolescents and young adults with Down syndrome. Dr.
- Trial name
- NCT02304302
- Testing
- Memantine
- Where
- 2 sites in United States, Brazil
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center