Clinical trials: Autologous Transplantation
Lymphoma
GM-CSF and Rituximab After Autologous Stem Cell Transplant in Treating Patients With Relapsed or Refractory Follicular Non-Hodgkin Lymphoma
RATIONALE: Giving high-dose chemotherapy before an autologous stem cell transplant helps stop the growth of cancer cells by stopping them from dividing or by killing them.
- Trial name
- NCT00521014
- Testing
- filgrastim, rituximab, sargramostim
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Pterygium, Primary
Conjunctival Autologous Transplantation Using Fibrin Glue in Primary Pterygia
To evaluate the recurrence and postoperative complications rates after conjunctival autograft surgery using fibrin adhesive for primary pterygium
- Trial name
- NCT00949728
- Testing
- Conjunctival autograft using fibrin glue
- Where
- Brazil
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Hospital de Olhos Sadalla Amin Ghanem
Acute Anterior Wall Myocardial Infarction
Autologous Stem Cell Transplantation in Acute Myocardial Infarction
Objectives Intracoronary transplantation of different cell populations have been used in acute myocardial infarction (AMI) with promising results.
- Trial name
- NCT00199823
- Testing
- Intracoronary aotologous stem cell transplantation
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Multiple Myeloma
A Pilot Study of the Combination of Melphalan, Bortezomib, Thalidomide and Dexamethasone (MEL-VTD)
In this study, researchers want to find out if using the VTD regimen, along with higher doses melphalan, in subjects who have relapsed or progressed after previous transplant(s), can be given safely to subjects who have failed…
- Trial name
- NCT00577668
- Testing
- Melphalan, Velcade, Thalidomide, Dexamethasone
- Where
- United States
- Sponsor
- University of Arkansas
Multiple Myeloma
Busulfan and Melphalan Conditioning in Multiple Myeloma
The purpose of this study is to determine whether intravenous busulfan and melphalan as a conditioning regimen is effective in the treatment of multiple myeloma undergoing autologous stem cell transplantation.
- Trial name
- NCT01923935
- Testing
- BUSULFEX®, Alkeran®
- Where
- 8 sites in South Korea
- Volunteers
- 105 people
- Sponsor
- Chonnam National University Hospital
Chronic Pancreatitis
Carbon Monoxide-Saturated Medium for Islet Isolation
The goal of this study is to determine whether harvesting islets using carbon monoxide (CO)-saturated mediums can protect islet cell from death after autologous islet transplantation in patients with chronic pancreatitis.
- Trial name
- NCT02567240
- Testing
- Carbon monoxide-bubbled mediums
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Medical University of South Carolina
Skin Rash
Effect of Palifermin on Skin Tumors in Patients Undergoing Bone Marrow Transplantation
We are approaching you to participate in this study because you are taking Palifermin and the purpose of this study is to describe the effect of Palifermin on skin growth found on the body.
- Trial name
- Palifermin (NCT00610818)
- Testing
- Palifermin
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Plasma Cell Myeloma
Melphalan Hydrochloride in Treating Participants With Newly-Diagnosed Multiple Myeloma Undergoing Donor Stem Cell Transplantation
This phase I/II trial studies the side effects and best dose of melphalan hydrochloride in treating participants with newly-diagnosed multiple myeloma who are undergoing a donor stem cell transplantation.
- Trial name
- NCT03417284
- Testing
- Autologous Hematopoietic Stem Cell Transplantation, Filgrastim-sndz, Melphalan Hydrochloride
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- M.D. Anderson Cancer Center
Sports Injury, Anterior Cruciate Ligament Rupture
Comparison of Functional Outcome Between BQT and SBHT ACL Reconstruction
ACL rupture has a high morbidity in productive-age population. The increasing incidence and proper management has become a point of interest in the musculoskeletal sport injury.
- Trial name
- BQTSBHTFMUI (NCT04536246)
- Testing
- Bone Quadriceps Tendon (BQT) arthroscopic-assisted ACL reconstruction, Single-Bundle Hamstring Tendon (SBHT) arthroscopic-assisted ACL reconstruction
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Acute Myocardial Infarction
Safety and Efficacy of Bone Marrow Cell Transplantation in Humans Myocardial Infarction
We will study in a prospective randomised fashion 50 patients who will be treated by intracoronary transplantation of autologous, mononuclear bone marrow cells (BMCs) in addition to standard therapy after MI or standard therapy.
- Trial name
- CARDIAC (NCT00437710)
- Testing
- cell therapy, bone marrow derived stem cell
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Azienda Unita Sanitaria Locale di Piacenza
Stem Cells, Type 1 Diabetes
Insulin Producing Stem Cell Transplantation Clinical Trial in Type 1 Diabetes
Type 1 Diabetes is a chronic autoimmune disease. It results from autoimmune destruction of pancreatic Beta cells leading to absolute insulin insufficiency.
- Trial name
- NCT06951074
- Testing
- Insulin producing stem cells infusion
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Lymphoma
Hematopoietic Stem Cell Transplant for Recurrent Non-Hodgkin's Lymphoma
The purpose of this study is to assess the safety of 131I-anti-B1 Radioimmunotherapy when combined with high-dose BEAM or BEAC chemotherapy and hematopoietic stem cell transplantation.
- Trial name
- NCT00574509
- Testing
- 131Iodine-Anti-B1 Radioimmunotherapy, BEAM
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Nebraska
Drug/Agent Toxicity by Tissue/Organ, Leukemia
Growth Factor to Prevent Oral Mucositis in Patients With Hematologic Cancer
RATIONALE: Keratinocyte growth factor may prevent symptoms of mucositis in patients receiving radiation therapy and chemotherapy.
- Conditions
- Drug/Agent Toxicity by Tissue/Organ, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00004132
- Testing
- filgrastim, palifermin, cyclophosphamide
- Where
- United States
- Sponsor
- Jonsson Comprehensive Cancer Center
Relapsed or Refractory Aggressive B-cell Lymphoma
Bispecific Antibody-Based Salvage Therapy Followed by CAR-T ± ASCT in R/R Aggressive B-Cell Lymphoma
This study consists of two sequential treatment phases. In the first phase, patients with r/r aggressive B-NHL receive two cycles of glofitamab ± investigator-selected agents.
- Trial name
- NCT06996132
- Testing
- Glofitamab, Chimeric Antigen Receptor T Cells (CAR-T)
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Breast Neoplasms, Neoplasm Metastasis
A Multimodality Treatment Approach to Patients With Inflammatory Cancer of the Breast and Locally Advanced Non-Inflammatory Stage III Breast Cancer and Stage IV Breast Cancer
This study is designed to evaluate the efficacy of high dose melphalan and autologous bone marrow transplantation given as consolidation therapy to patients with inflammatory or metastatic carcinoma of the breast in complete…
- Trial name
- NCT00001193
- Testing
- high dose melphalan and autologous bone marrow transplantation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Cancer Institute (NCI)
Anterior Cruciate Ligament Rupture
Adductor Canal Block and IPACK Block vs. Isolated Adductor Canal Block for Post-Operative Analgesia Following ACL Reconstruction With Bone Patellar Tendon Bone Autograft:
A randomized, single-blind, single-center study measuring the effects of adductor canal block combined with IPACK infiltration compared to adductor canal block alone on post-operative pain and opioid consumption in patients…
- Trial name
- NCT05286307
- Testing
- IPACK block
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- NYU Langone Health
Multiple Myeloma
Efficacy of Bortezomib Consolidation After High-dose Melphalan With Stem Cell Support in Myeloma Patients
Multiple myeloma is a malignant incurable hematological disease where survival has been significantly improved by high-dose melphalan with autologous stem cell support (ASCT) in younger patients.
- Trial name
- NCT00417911
- Testing
- bortezomib
- Where
- 20 sites in Denmark, Finland and 3 more
- Volunteers
- 400 people
- Sponsor
- Nordic Myeloma Study Group
Multiple Myeloma, Non-Hodgkin Lymphoma
Music Therapy on Nausea and Pain for Autologous Stem Cell
Autologous stem cell transplant (ASCT) is an important therapy for patients with multiple myeloma, non-Hodgkin's lymphoma, and Hodgkin's lymphoma. It has been shown to improve progression free survival and overall survival.
- Conditions
- Multiple Myeloma, Non-Hodgkin Lymphoma, Hodgkin Lymphoma
- Trial name
- NCT01487031
- Testing
- Music Therapy, No music therapy
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Case Comprehensive Cancer Center
Interstitial Lung Diseases
Autologous Lung Stem Cell Transplantation in Patients With Interstitial Lung Diseases
Interstitial lung diseases (ILD) are a group of diseases affecting the lung interstitium. The lung scarring that occurs in ILD is often irreversible with only mitigating therapy available so far.
- Trial name
- NCT02796781
- Testing
- Lung stem cells
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Shanghai East Hospital
Multiple Myeloma
Study of Carfilzomib in Multiple Myeloma Relapsed After High-dose Melphalan With Autologous Stem Cell Support
This study evaluates induction therapy with carfilzomib-cyclophosphamide-dexamethasone before salvage high-dose melphalan with autologous stem cell support (HDT) in multiple myeloma patients with relapse after HDT done at…
- Trial name
- CARFI (NCT02572492)
- Testing
- Induction with CAR-CY-DEX and conditioning with carfilzomib and highdose melphalan, Carfilzomib/dexamethasone maintenance, Observation without carfilzomib/dexamethasone maintenance
- Where
- 5 sites in Denmark, Finland and 3 more
- Volunteers
- 200 people
- Sponsor
- Henrik Gregersen
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