Clinical trials: Autonomic Imbalance
Physical Activity, Emotions
Lighting and Human Response in Motor Time, Autonomic Nervous System, and Emotion
Light influences on human movement, autonomic nervous system, and emotion. It is inconclusive whether illuminance (Ev) and colour temperature (Tc) is appropriate to human movement, autonomic nervous systme, and emotion.
- Conditions
- Physical Activity, Emotions, Autonomic Nervous System Imbalance
- Trial name
- LiHR (NCT03144791)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Schizophrenia, Schizoaffective Disorder
The Effects of tDCS on Auditory Hallucination, Insight, Neurocognitive Function and HRV in Patients With Schizophrenia
The study aimed to investigate whether transcranial direct current stimulation could modify auditory hallucination, insight, neurocognitive function, heart rate variability, psychosocial functioning and quality of life in…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Auditory Hallucination, Verbal, Neurocognitive Dysfunction
- Trial name
- NCT03388554
- Testing
- tDCS
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Autonomic Nervous System Imbalance, Healthy
Effects of OMT on ANS: a Thermography Study
the study will investigate the effect of a specific type of touch intervention on the activity of autonomic nervous system measured using thermography
- Trial name
- NCT03888456
- Testing
- osteopathic treatment
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Come Collaboration
Septic Shock
Neuromodulation to Regulate Inflammation and Autonomic Imbalance in Sepsis
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. It is the most expensive healthcare condition to treat in United States and has a mortality rate of nearly 30%.
- Trial name
- NERINASEPSIS (NCT03992378)
- Testing
- Low Level Transcutaneous Vagus Nerve Stimulation
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Oklahoma
Functional Gastrointestinal Disorders, Hypermobile Ehlers-Danlos Syndrome
Auricular Vagal Nerve Stimulation for Hypermobile Ehlers-Danlos Syndrome
Hypermobile Ehlers-Danlos Syndrome (hEDS) is a connective tissue disorder characterized by hyperextensible skin, joint hypermobility and additional connective tissue manifestations.
- Conditions
- Functional Gastrointestinal Disorders, Hypermobile Ehlers-Danlos Syndrome, Postural Orthostatic Tachycardia Syndrome, Autonomic Nervous System Disease
- Trial name
- NCT05212129
- Testing
- Percutaneous vagal nerve stimulation (pVNS) device, Acoustic vagal nerve stimulation (aVNS) treatment
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Medical College of Wisconsin
Autonomic Imbalance
Effect of a Sequence of Specific Manual Therapy Techniques Targeting the Autonomic Nervous System in Healthy Adults
The activity of the autonomic nervous system has been shown to influence the appearance of symptoms in some diseases such as rheumatoid arthritis, fibromyalgia, or migraine, among others.
- Trial name
- NCT06477822
- Testing
- Sequence of manual therapy techniques, Simulated manual therapy techniques
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Brachial Plexus Block, Horner Syndrome
The Effects of Horner's Syndrome Developing After Interscalene Brachial Plexus Block on Autonomic Nervous Activity
This study evaluates the effects of Horner's syndrome on cardiac autonomic nervous activity after interscalene brachial plexus block.
- Conditions
- Brachial Plexus Block, Horner Syndrome, Autonomic Imbalance
- Trial name
- NCT03514342
- Testing
- Interscalene brachial plexus block, 0.75% ropivacaine
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Daegu Catholic University Medical Center
Autonomic Nervous System Imbalance
Metabolism and the Activity of the Autonomic Nervous System in Patients With Paroxystic Sympathetic Hyperactivity, PSH
Adult patients suffering from acquired brain damage run the risk of developing PSH. This group of patients is admitted to our unit, the Neurointensive Stepdown Unit, at Silkeborg Regional Hospital for intensive care and early…
- Trial name
- MANS-PSH (NCT03441009)
- Testing
- Physio-/occupational therapy
- Volunteers
- 15 people
- Sponsor
- Region MidtJylland Denmark
Female Sexual Arousal Disorder
Heart Rate Variability Biofeedback for Female Sexual Arousal Disorder
Low resting heart rate variability (HRV) has been associated with sexual arousal problems and overall sexual dysfunction in women.
- Trial name
- NCT02958176
- Testing
- HRV Biofeedback, Autogenic Training
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Texas at Austin
Spinal Cord Injuries, Autonomic Imbalance
Deciphering Preserved Autonomic Function After Spinal Cord Injury
This study looks to characterize gradients of dysfunction in the autonomic nervous system after spinal cord injury. The autonomic nervous system plays key roles in regulation of blood pressure, skin blood flow, and bladder…
- Conditions
- Spinal Cord Injuries, Autonomic Imbalance, Autonomic Dysreflexia, Orthostatic Hypotension
- Trial name
- NCT04493372
- Testing
- Tests of sympathetic inhibition, Tests of sympathetic activation, Testing of autonomic dysreflexia
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Ventricular Septal Defect, Closure; Interventricular Septum
The Effect of Transcatheter Ventricular Septal Defect Closure on Heart Rate Variability Parameters
In this study; we evaluated the heart rate variability parameters of pediatric patients whose VSDs were closed with the transcatheter method before and after, and compared with the control group.
- Conditions
- Ventricular Septal Defect, Closure; Interventricular Septum, Autonomic Nervous System Imbalance
- Trial name
- NCT04859036
- Testing
- 24 hours ambulatory Holter monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Hypertension, Hypertensive Heart Disease
Renal Sympathetic Denervation Prevents Atrial Fibrillation in Patients With Hypertensive Heart Disease: a Pilot Study
The autonomic nervous system plays an important role in the precipitation of AF in structurally-abnormal hearts. Restoration of autonomic imbalance may therefore prevent new-onset AF.
- Conditions
- Hypertension, Hypertensive Heart Disease, Atrial Fibrillation, Autonomic Imbalance
- Trial name
- RDPAF (NCT01990911)
- Testing
- Renal denervation, Medical therapy
- Where
- South Africa
- Volunteers
- 80 people
- Sponsor
- Pace Clinic
Spinal Cord Injuries, Autonomic Imbalance
Transcutaneous Spinal Cord Neuromodulation to Normalize Autonomic Phenotypes
This study looks to characterize autonomic nervous system dysfunction after spinal cord injury and identify the potential role that transcutaneous spinal cord stimulation may play at altering neuroregulation.
- Conditions
- Spinal Cord Injuries, Autonomic Imbalance, Autonomic Dysreflexia, Orthostatic; Hypotension, Neurogenic
- Trial name
- NCT04858178
- Testing
- Tests of sympathetic inhibition, Tests of sympathetic activation, Testing of autonomic dysreflexia
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Heart Failure, Autonomic Nervous System Imbalance
Evaluation of the Six Minute Walk Test and Other Instruments in Heart Failure
The purpose of this study is to assess functional capacity, quality of life and functioning of the autonomic nervous system in heart failure patients on beta-blocker treatment.
- Conditions
- Heart Failure, Autonomic Nervous System Imbalance, Heart Rate and Rhythm Disorders, Quality of Life
- Trial name
- NCT01736137
- Testing
- Six minute walk test
- Where
- Brazil
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Prehypertension, Blood Pressure
HIRREM for Pre-Hypertension
This randomized, controlled clinical pilot trial will evaluate the effects associated with in-office use of closed-loop, acoustic stimulation neurotechnology (High-resolution, relational, resonance-based, electroencephalic…
- Conditions
- Prehypertension, Blood Pressure, Autonomic Nervous System Imbalance, Cardiovascular Risk Factor
- Trial name
- NCT03332043
- Testing
- HIRREM, Ambient Nature Sounds
- Sponsor
- Wake Forest University Health Sciences
Autonomic Nervous System Imbalance
Effect of CES on Parasympathetic Tone
The hypothesis is that CES stimulation will dose dependently increase parasympathetic tone. Healthy subjects will have three 20 minute sessions of CES stimulation, at three different intensities of stimulation, with each session…
- Trial name
- NCT02163967
- Testing
- Cranial Electrical Stimulation Fisher-Wallace Stimulator (Model FW100)
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Schizophrenia, Schizoaffective Disorder
Theta tACS During Working Memory Training: A Pilot Study of the Effects on Negative Symptoms of Schizophrenia
In this randomized double-blind trial, we investigated whether externally induced left-hemispheric frontoparietal theta synchronization by multi-electrode online theta (6Hz) transcranial alternating current stimulation (tACS)…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Negative Symptoms, Working Memory Training
- Trial name
- NCT04545294
- Testing
- Theta tACS
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Peripheral Artery Disease, Endothelial Dysfunction
Effect of Transcutaneous Vagal Stimulation (TVS) on Endothelial Function in PAD
Peripheral arterial disease (PAD) constitutes a major public health burden. The incidence of PAD increases with age and is associated with other comorbid cardiovascular disorders.
- Conditions
- Peripheral Artery Disease, Endothelial Dysfunction, Autonomic Imbalance
- Trial name
- TVS-PAD (NCT03445754)
- Testing
- TVS
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Oklahoma
Physical Fitness, Patient Adherence
Home-based Exercise Training in Cardiac Patients
The investigators hypothesize that exercise training program guided by virtual augmented reality glasses or by video from computer screen used at home will improve motivation into exercise training and results in superior…
- Conditions
- Physical Fitness, Patient Adherence, Quality of Life, Autonomic Nervous System Imbalance
- Trial name
- VAPA-Oulu (NCT03704025)
- Testing
- Current guidelines rehabilitation, Mobile device guided rehabilitation
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- University of Oulu
Autonomic Nervous System Imbalance
Heart Rate Variability of Premature Newborn
To analyze the effects of two CPAP methods on the HRV of PTNBs during their routine routine in the HCUFU neonatal ICU. This is a randomized clinical trial, with controlled groups and cross over with healthy term newborns (RNT) as…
- Trial name
- HRV (NCT06217133)
- Testing
- CPAP
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia