Clinical trials: Autonomic Nervous System Activity
COPD, Sympathetic Nervous System Diseases
Sympathetic Nerve Activity Predictors in Patients With Chronic Obstructive Pulmonary Disease
The project will be pursued in our respiratory, autonomic nervous system physiology laboratory (Respiratory, autonomic nervous system physiology laboratory, Department of Pneumology and Intensive Care Medicine, RWTH Aachen…
- Conditions
- COPD, Sympathetic Nervous System Diseases, Catecholamine; Overproduction
- Trial name
- SNAP-COPD (NCT04849806)
- Testing
- Assessments of the sympathetic nerve activity axis, OSA severity, Determination of PH and right HF severity
- Where
- Germany
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Hemodynamic, Exercise
Sex and Exercise-mode Differences in Post Exercise Blood Pressure and Heart Rate Variability Responses During Workday
The present study compared the acute effects of Sex and exercise mode on subsequent blood pressure (BP) and heart rate variability (HRV) responses during daily work in healthy adults.
- Trial name
- NCT03080636
- Testing
- Aerobic exercise, Resistance exercise, Control session
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Neurodevelopmental Disorders
The Effect of Physical Activity Autonomic Response of Autism Spectrum
This study will investigate the effect of physical activity on autism spectrum disorder (ASD) in individuals with ASD of different age groups through measuring the hemodynamic, heart activity and respiratory system parameters.
- Trial name
- NCT05725733
- Testing
- Physical Therapy
- Where
- Saudi Arabia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Jazan
Body Composition, Fitness
Evaluation of Molecular Hydrogen Supplementation to Enhance the Efficacy of Weight Loss Retreat in Overweight and Obese Adolescents
This randomized controlled trial evaluates whether molecular hydrogen supplementation enhances the effectiveness of a 4-week weight loss retreat in overweight and obese adolescents.
- Conditions
- Body Composition, Fitness, Insulin Sensitivity, Lipid Profile
- Trial name
- NCT06961110
- Testing
- Hydrogen-rich water
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Palacky University
Type 2 Diabetes, Diabetes Mellitus, Type 2
Heart Rate Variability-Guided Exercise Training in Type 2 Diabetes
The primary aim of this randomized clinical trial is to determine the effectiveness of a 16 wk individualized aerobic exercise program, using heart rate variability to guide the exercise prescription, for increasing aerobic…
- Conditions
- Type 2 Diabetes, Diabetes Mellitus, Type 2, Type 2 Diabetes Mellitus in Obese
- Trial name
- NCT04910997
- Testing
- Aerobic exercise training
- Where
- United States
- Sponsor
- University of Illinois at Chicago
Posttraumatic Stress Disorder
Impact of Cognitive Behavioral Therapy on PTSD-CVD Link
This is a pilot randomized controlled trial to assess the impact of a first-line treatment for posttraumatic stress disorder (PTSD) (Cognitive Processing Therapy; CPT) versus waitlist control on mechanisms of cardiovascular…
- Trial name
- NCT06429293
- Testing
- Cognitive processing therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital
Healthy
Evaluation of Aging, Autonomic Nervous System Activity and Cardiovascular Events
The regulatory effects of the autonomic nervous system (ANS) concern almost all organs which permanently feed information back to this global biological vigilance system controlling allostasis.
- Trial name
- PROOF (NCT00759304)
- Where
- France
- Volunteers
- 1,011 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Autonomic Nervous System Activity
Vagotonic Effect of Remifentanil and Autonomic Nervous System Activity.
Remifentanil (RMFNT) is a very short active opioid, used for analgesia during general anaesthesia and for analgesic and sedative effect in intensive care units (ICU) patients.
- Trial name
- NCT01714388
- Testing
- Remifentanil
- Where
- Poland
- Volunteers
- 70 people
- Sponsor
- Medical University of Gdansk
Leiomyoma
Vascular Function and Uterine Fibroids
The purpose of this study is to learn how uterine fibroids may be connected to heart disease and high blood pressure. It is not known what causes fibroids, but they frequently occur in women who also have high blood pressure…
- Trial name
- NCT02123069
- Testing
- Brachial artery catheter, Acetylcholine, Nitroprusside
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Healthy
Osteopathic Manipulative Treatment and Its Relationship to Autonomic Nervous System Activity
The relationship between Osteopathic Manipulative Therapy (OMT) and the autonomic nervous system is poorly understood. This study quantifies that relationship and demonstrates a cause and effect.
- Trial name
- NCT00516984
- Testing
- OMT
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Hypertension, Resistant to Conventional Therapy
Peripheral Chemoreflex/Arterial Baroreflex Interaction in Patients With Electrical Carotid Sinus Stimulation
Peripheral chemoreceptors and baroreceptors are located in close proximity in the carotid artery wall at the level of the carotid bifurcation. Baroreceptor stimulation lowers sympathetic activity and blood pressure.
- Trial name
- ChemoBar (NCT02587533)
- Testing
- Hypoxia without dopamine, Hypoxia with dopamine, Hyperoxia without dopamine
- Where
- Germany
- Volunteers
- 11 people
- Sponsor
- Hannover Medical School
Bruxism
Chewing Muscles in Bruxers
The aim of this study was to determine the relationship between autonomic nervous system activity and tonus, stiffness and elasticity of temporalis and masseter muscles in individuals with bruxism and to compare them with healthy…
- Trial name
- NCT06824766
- Testing
- Visual Analogue Scale, Autonomic nervous system activity assessment, Masticatory muscles assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Bradycardia During Pulling of Eyeball
Autonomic Nervous System Activity and Oculocardiac Reflex.
Pulling the eyeball during ophthalmic surgery provokes decrease in heart rate. This phenomenon is called oculocardiac reflex. In some patients asystole may occur.
- Trial name
- NCT01714362
- Where
- Poland
- Volunteers
- 52 people
- Sponsor
- Medical University of Gdansk
Cerebral Palsy, Autonomic Nerveus System
BioFeedBack Breathing Training Influence Cardiac Autonomic Nervous System in Children With Cerebral-Palsy.
The effect of breathing biofeedback training to influence the function of the cardiac autonomic nervous system at rest and in activity in children with cerebral palsy.
- Trial name
- NCT01872507
- Testing
- Biofeedback training
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hadassah Medical Organization
Healthy, Vasodilation
Impact of Intranasal Insulin on Sympathetic Activity and Cerebral Vasodilation
The purpose of this project is to examine the impact of increases in brain insulin on sympathetic nervous system activity, as well as peripheral and cerebral blood flow in humans.
- Conditions
- Healthy, Vasodilation, Insulin Resistance, Autonomic Dysfunction
- Trial name
- NCT05153395
- Testing
- Carbon dioxide breathing, Neurovascular Coupling, Human insulin
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Alcoholism, Healthy
The Effect of Positive and Negative Emotions on Brain Activity in Alcoholics and Nonalcoholics
This study was designed to learn more about the areas of the brain involved in the experience of positive and negative emotions.
- Trial name
- NCT00001675
- Where
- United States
- Volunteers
- 1,194 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Advanced Solid Tumor
A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors
This is a study to evaluate the safety and potential anti-tumor activity of an investigational drug called ARV-6723, in participants with advanced solid tumors.
- Trial name
- NCT07749586
- Testing
- ARV-6723, Pembrolizumab, SOC
- Where
- 4 sites in United States
- Volunteers
- 499 people
- Sponsor
- Arvinas Inc.
Fullterm Birth, Neonate
Assessment of Autonomic Maturation in Neonatal Period and Early Neural Development From a Longitudinal Prospective Cohort
The heart rate variability assessment of the sympathetic-parasympathetic balance is a strong analytical tool in the autonomic nervous system (ANS) physiology, at each end of life.
- Conditions
- Fullterm Birth, Neonate, Prematurity
- Trial name
- AUBE (NCT00951860)
- Testing
- Autonomic Nervous System activity
- Where
- France
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne