Clinical trials: Autonomic Nervous System Disorders
Hypoglycemia, Type 2 Diabetes
Hypoglycemia (Low Blood Sugar) and the Heart
The risk of hypoglycemia (low blood sugar) associated with the treatment of diabetes increases with age. Hypoglycemia is a common reason for admission to hospital for older patients with diabetes.
- Trial name
- NCT01980914
- Testing
- iPro2 glucose sensor attachment
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University of British Columbia
Autonomic Nervous System Disease, Healthy
Blood Sampling for Neurochemical and Genetic Testing
This study involves sampling blood from both normal volunteers and patients with diseases known or suspected to involve body chemicals called catecholamines.
- Conditions
- Autonomic Nervous System Disease, Healthy, Hypertension, Pheochromocytoma
- Trial name
- NCT00001147
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Postural Tachycardia Syndrome, Syncope
Qualitative Sweat Distribution During Tilt Table Procedure
This study uses an Alizarin Red powder mixture to characterize the sweat distributions in youth during tilt table testing. Patients with a known orthostatic sweat response from a prior clinical tilt table test in the…
- Conditions
- Postural Tachycardia Syndrome, Syncope, Anxiety
- Trial name
- NCT02329548
- Testing
- Alizarin Red
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Nationwide Children's Hospital
Tobacco Use Disorder, Substance-Related Disorders
Behavioral Economic Purchasing Decisions for Cigarettes of Varied Compositions
The purpose of this study is to determine whether the abuse liability of cigarettes with altered composition (cigarettes differing in composition; e.g., tar levels, amount of sugar, casings) is reduced relative to standard…
- Trial name
- NCT02888249
- Testing
- Altered composition cigarette
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Johns Hopkins University
Blood Donors
Addressing Fear and Risk of Vasovagal Reactions Among High School Donors
In this study, high school donors will be asked about their blood donation-related fears prior to their donation. Half of the donors reporting fear will be assigned to a brief coping skills intervention.
- Trial name
- NCT03835299
- Testing
- Fear Intervention
- Where
- United States
- Volunteers
- 4,035 people
- Sponsor
- Ohio University
Complex Regional Pain Syndrome Type I
Pain in Complex Regional Pain Syndrome
CRPS is a complex pain condition that usually develops in response to trauma and immobilization which is very painful and debilitating.
- Trial name
- NCT04667364
- Testing
- Transcutaneous electrical nerve stimulation (TENS)
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Myocardial Infarction
Innovative Stratification of Arrhythmic Risk (ISAR-Trial): Female Patients
The purpose of this study was to investigate differences in risk prediction in female post-infarction patients.
- Trial name
- NCT00196287
- Where
- 2 sites in Germany
- Volunteers
- 750 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Pancreatic Cancer, ATM, BRCA, Hereditary Cancer
Pancreatic Cancer Registry: For Any Person With a Personal or Family History
The NFPTR was established in 1994 to find the causes of pancreatic cancer. In brief, the investigators are interested in both the genetic and non-genetic causes of pancreatic cancer.
- Trial name
- NFPTR (NCT02886247)
- Where
- United States
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Autonomic Nervous System Disease, Spinal Cord Injuries
The Effects of an Acute High-intensity Exercise on Heart and Brain Function in People With Spinal Cord Injury
The heart and brain are regulated by the autonomic nervous system. Control of these organs can be disrupted in people with spinal cord injury (SCI).
- Conditions
- Autonomic Nervous System Disease, Spinal Cord Injuries, Cognition
- Trial name
- NCT06274658
- Testing
- High-intensity interval exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Multiple System Atrophy, Parkinson Disease
UB-312 in Patients With Synucleinopathies
This is a Phase 1b study to determine the safety, tolerability, and immunogenicity of UB-312 in participants with multiple system atrophy (MSA), and in participants with Parkinson's disease (PD).
- Trial name
- NCT05634876
- Testing
- UB-312 Injection
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- NYU Langone Health
Post-Concussion Syndrome
Post-concussion Syndrome and Chiropractic
This proof-of-concept trial will explore the effects of manual chiropractic adjustments on nervous system function in individuals with post-concussion syndrome.
- Trial name
- PCS (NCT06151184)
- Testing
- Chiropractic adjustment
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Life University
Type 1 Diabetes (Juvenile Onset), Type 1 Diabetes
Type 1 Diabetes Autonomic and Vascular Function
The goal of this clinical trial is to investigate the autonomic and vascular function in men and women with Type 1 diabetes. The main questions it aims to answer are: 1.
- Conditions
- Type 1 Diabetes (Juvenile Onset), Type 1 Diabetes, Diabetes, Autoimmune
- Trial name
- NCT06786546
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Postural Tachycardia Syndrome
Modafinil and Cognitive Function in POTS
A common complaint among patients with Postural Tachycardia Syndrome (POTS) is "brain fog" or difficulty concentrating. This problem is poorly understood.
- Trial name
- NCT01988883
- Testing
- Modafinil, Propranolol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vanderbilt University Medical Center
Complex Regional Pain Syndrome (CRPS) TYPE I
Role of Vitamin C at 6 Months on Incidence of Complex Regional Pain Syndrome Type I in Upper Limb Surgery
Vitamin C with its antioxidant role has many indications. The objective of this study is to demonstrate that taking vitamin C as a preventive significantly reduces the occurrence of complex regional pain syndrome (CRPS) type 1 in…
- Trial name
- SDRC (NCT02390505)
- Testing
- Vitamin C
- Where
- 3 sites in France
- Volunteers
- 995 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Migraine Disorders
Cognitive Function and Autonomic Regulation in Patients With Migraine
Individuals with migraine have impaired cognitive function and worse autonomic function compared to individuals without migraine.
- Trial name
- NCT04272229
- Testing
- Cognition, Sympathetic Nervous System, Concentratio and Attention
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fortaleza University
Hypertension
Effectiveness of Yoga on Ambulatory Blood Pressure in Patients With Pre- and Stage I Hypertension
The proposed study will compare a well defined and integrated yoga practice (postures/breath control/meditation) to a conventional exercise program in reducing hypertension.
- Trial name
- NCT01542359
- Testing
- Yogic practice, Conventional Exercise
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Long Island University
Complex Regional Pain Syndrome (CRPS)
Effects of Non-invasive Brain Stimulation on Pain Avoidance Behavior in Chronic Pain Patients
Pain avoidance helps with survival. However, chronic pain patients often avoid valued life activities fearing onset or exacerbation of pain. Hence, pain avoidance no longer protects, but reduces quality of life.
- Trial name
- NCT07791966
- Testing
- transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The Cleveland Clinic
CRPS I, Causalgia
Trialing of ISS in Patients With CRPS
This is a multi-center, prospective, open-label, single-arm, observational, feasibility study. The goal of this study is to determine the feasibility of intra-spinal stimulation with optimal paresthesia coverage therapy for…
- Trial name
- NCT03954080
- Testing
- Intraspinal-optimal stim therapy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Millennium Pain Center
Ischemic Stroke
The Impact of Electroacupuncture Combined With NGF on Clinical Effect and Functional Changes on Ischemic Stroke
Ischemic stroke is a common clinical disease, often accompanied by motor dysfunction and cognitive impairment. At present, clinical treatment for patients with ischemic stroke recovery is limited and ineffective.
- Trial name
- NCT05231694
- Testing
- Nerver growth factor (NGF) injection, EA intervention
- Where
- China
- Volunteers
- 288 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Cardiovascular Diseases, Post-Exercise Hypotension
The Influence of Cardiorespiratory Fitness on Firefighter Cardiovascular Health Under Exercise Conditions
Sudden cardiac death (SCD) is the number one cause of on-duty firefighter death. It is most likely to occur in adults who are not physically fit that engage in sudden vigorous exercise.
- Trial name
- FIT & FIRED UP (NCT04514354)
- Testing
- GEST
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Connecticut
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.