Clinical trials: Autonomy
Prostatic Neoplasms, Anemia
Effect of Darbepoetin Alfa (Aranesp®) on Anemia in Patients With Advanced Hormone Independent Prostate Cancer
The purpose of this study is to determine whether or not Aranesp® (Darbepoetin Alfa), administered every fourth week, is effective in the treatment of blood shortage (anemia) compared to standard care of treatment (blood…
- Trial name
- NCT00381836
- Testing
- Darbepoetin Alfa
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- University of Aarhus
Dental Caries, Elderly
Pilot and Feasibility Study of Impact of SDF 38% Application on Oral Health of Elderly With Autonomy Loss
Introduction: Dental caries constitutes a major oral health problem at a global scale for the elderly population. It impacts the health system due to its high incidence and prevalence and its associated costs.
- Conditions
- Dental Caries, Elderly, Loss of Autonomy, Silver Diamine Fluoride
- Trial name
- NCT07194629
- Testing
- Silver diamine Fluoride 38%
- Where
- 3 sites in Canada
- Volunteers
- 60 people
- Sponsor
- Université de Montréal
Healthy, Stroke
The Influence of Cortical Lateralization on Selective Motor Control of the Arm Swing During Independent Walking After Stroke.
The upper limbs play an essential role for safe and efficient walking in healthy persons and persons post-stroke. Nevertheless, in current post-stroke gait rehabilitation (research) the upper limbs are barely targeted.
- Trial name
- NCT06442579
- Testing
- Walking on a treadmill
- Where
- 2 sites in Belgium
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Postoperative Bleeding, Patient Satisfaction
Reducing Postoperative Bleeding After Hysterectomy Via Independent Closure of Vaginal Cuff Angles
The investigators propose prospectively evaluating if adding separate sutures to the angles of the vaginal cuff before running barbed suture reduces the incidence of patient's perception of bleeding after surgery.
- Conditions
- Postoperative Bleeding, Patient Satisfaction, Complications, Operative Time
- Trial name
- NCT05174988
- Testing
- Angle stitch
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Muscle Hypertrophy, Muscle Strength
Upper Versus Lower Limb Responses to Higher Versus Lower Load Resistance Training in Young Men
Recent research suggests that performing resistance exercise training with relatively light loads is equally as effective at increasing muscle mass and muscle strength as performing resistance exercise training with relatively…
- Trial name
- NCT03993483
- Testing
- Unilateral resistance exercise
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McMaster University
HIV Infections
Getting to Zero Among HHI MSM in the American South
This study will evaluate a status-neutral integrated strategy to improve access to and uptake of HIV prevention and treatment services for the highest HIV incidence (HHI) men who have sex with men (MSM) in participating…
- Trial name
- NCT05075967
- Testing
- Health Access Coalitions, Social Media, Peer Support
- Where
- United States
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- HIV Prevention Trials Network
Acinar Cell Carcinoma, Adenoid Cystic Carcinoma
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors
This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may…
- Conditions
- Acinar Cell Carcinoma, Adenoid Cystic Carcinoma, Adrenal Cortical Carcinoma, Adrenal Gland Pheochromocytoma
- Trial name
- NCT02834013
- Testing
- Biospecimen Collection, Computed Tomography, Echocardiography Test
- Where
- 1,007 sites in United States, Guam
- Volunteers
- 798 people
- Sponsor
- National Cancer Institute (NCI)
Under-nutrition or Risk of Undernutrition
Clinical and Medico-economic Evaluation of Taken Care Associating Nutritional Support and Adapted Physical Activity for Malnourished, or at Risk of Undernutrition, Elderly People on Discharge From Hospital
In the hospital, one out of every two elderly people is malnourished. This condition of undernutrition generally worsens during hospitalization, where the effects of polypathology and psychological distress are added.
- Trial name
- NUTRIACTIF (NCT03979560)
- Testing
- Intervention
- Where
- France
- Volunteers
- 47 people
- Sponsor
- Gérond'if
Old Age
Multi-nutrient Supplement to Improve Physical Performance in Older Adults
Geriatric Day Hospitals (GDH) of the McGill University Health Centre and l'Institut de Gériatrie de Montreal offer comprehensive rehabilitation programs including physiotherapy and medical care, but no dietetic counselling for…
- Trial name
- NCT04454359
- Testing
- Multi-nutrient supplement
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McGill University
Major Neurocognitive Disorder
GPS Project Evaluation of the Impact of the Reorganization of Work Into a Family Medicine Group on Pharmacotherapy and Support for the Autonomy of Seniors With Major Neurocognitive Disorders
The model of care tested in the GPS project aims to optimize pharmacotherapy for seniors undergoing cognitive assessment or suffering from major neurocognitive disorder (MCND) at home.
- Trial name
- NCT04889794
- Testing
- GPS clinical intervention
- Where
- 2 sites in Canada
- Volunteers
- 400 people
- Sponsor
- CHU de Quebec-Universite Laval
Lower Limb Amputation
Sit-to-stand Trainer in Patients After Lower Limb Amputation
The study will include rehabilitation inpatients after unilateral lower limb amputation who are candidates for walking with a prosthesis.
- Trial name
- STSTrainer (NCT04086069)
- Testing
- Sit-to-stand trainer
- Where
- Slovenia
- Sponsor
- University Rehabilitation Institute, Republic of Slovenia
Cardiovascular Diseases
Hypolipidemic and Antioxidant Capacity of Spirulina and Exercise
The purpose of this study is to demonstrate that Spirulina maxima intake and a dosed physical activity program will decrease, both independently and synergistically, cardiovascular risks (Dyslipidemias and oxidative stress) in…
- Trial name
- NCT02837666
- Testing
- Supplementation with Spirulina maxima, Washout, Isoenergetic diet
- Where
- Mexico
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Ciudad Juarez
Frailty in Older Adults, Intrinsic Capacity
Optimizing INtrinsic Capacity for Functional INdependence and to Impede FrailTY in Older Adults: Adaptation of the WHO-ICOPE for Healthy Ageing in Singapore
The goal of this intervention study is to screen and identify frailty and decline in intrinsic capacity (physical and mental capacities) in community-dwelling older adults in Singapore, and to evaluate whether early…
- Conditions
- Frailty in Older Adults, Intrinsic Capacity, Age-related Functional Decline, Healthy Ageing
- Trial name
- INFINITY-ICOPE (NCT07477561)
- Testing
- INFINITY-ICOPE programme
- Where
- Singapore
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sengkang General Hospital
Neuropathic Pain, Pain
Optimized Programming in Spinal Cord Stimulation (SCS) System
The objective of this study is to evaluate extent, location, and perception of paresthesia as a function of anode/cathode configuration.
- Trial name
- OP (NCT00871819)
- Testing
- Precision Spinal Cord Stimulation (SCS)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Sedentary Lifestyle, Risk of Disability
The LIFE Study - Lifestyle Interventions and Independence for Elders
Based upon promising results from a pilot study among 424 sedentary older adults who were randomized to a physical activity intervention or a successful aging health education intervention, a Phase 3 multi-center randomized…
- Conditions
- Sedentary Lifestyle, Risk of Disability, Aging
- Trial name
- LIFE (NCT01072500)
- Testing
- Physical Activity, Successful Aging
- Where
- 8 sites in United States
- Volunteers
- 1,635 people
- Sponsor
- University of Florida
Surgical Education
Operative Curriculum Gallbladder Surgery
The goal of this study is to implement and evaluate the need, feasibility and effectiveness of a resident-initiated, step-wise, graduated operative curriculum designed to enhance resident autonomy for laparoscopic cholecystectomy…
- Trial name
- NCT04691206
- Testing
- briefing objectives, intraoperative teaching, and debriefing feedback
- Where
- 3 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cataract, Cataract Senile
Prospective Evaluation of the Tecnis Symfony Intraocular Lens (IOL)
Advances in cataract surgery and premium IOLs have allowed the ophthalmologist and optometrist to embrace the fact, as with Lasik patients, that refractive cataract surgery can allow their patients to be potentially free or less…
- Trial name
- NCT03579368
- Testing
- Symfony implantation
- Volunteers
- 200 people
- Sponsor
- Kovach Eye Institute
Malignant Neoplasm of Bone and Articular Cartilage, Malignant Neoplasms of Female Genital Organs
Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases
Any time the words "you," "your," "I," or "me" appear, it is meant to apply to the potential participant. The goal of this clinical research study is to find the highest tolerable dose of gemcitabine that can be given by…
- Conditions
- Malignant Neoplasm of Bone and Articular Cartilage, Malignant Neoplasms of Female Genital Organs, Malignant Neoplasms of Independent (Primary) Multiple Sites, Malignant Neoplasms of Lip Oral Cavity and Pharynx
- Trial name
- NCT03093909
- Testing
- Gemcitabine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- M.D. Anderson Cancer Center
Malignant Neoplasms of Independent (Primary) Multiple Sites
Effect of Physician Attire on Patients' Preference of Physician
The goal of this research study is to learn about the effects of a doctor's characteristics on participant's preference for a doctor.
- Trial name
- NCT03168763
- Testing
- Video, Questionnaires
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- M.D. Anderson Cancer Center
Cancer, Advanced
Histology-Independent Study of Palbociclib in Patients With Advanced Cancer
The investigational drug being tested in this study is palbociclib. Palbociclib is considered experimental because it is not approved by the FDA for the treatment of all cancers.
- Trial name
- NCT03123744
- Testing
- Palbociclib 125mg
- Where
- United States
- Sponsor
- Razelle Kurzrock, MD