Clinical trials: Autotransplantation
Anterior Cruciate Ligament Injury
BPTB Versus Hamstring Autografts in ACL Reconstruction Among Professional Athletes
This prospective randomized controlled study compares outcomes of ACL reconstruction using bone-patellar tendon-bone (BPTB) versus hamstring tendon (HT) autografts in professional athletes.
- Trial name
- BPTB-HT ACL (NCT07573293)
- Testing
- BPTB ACL Reconstruction, Hamstring ACL Reconstruction
- Where
- Egypt
- Volunteers
- 65 people
- Sponsor
- Cairo University
Skin Wound, Burns
StrataGraft® Skin Tissue as an Alternative to Autografting Deep Partial-Thickness Burns
The proposed study is designed as a phase Ib open-label, dose-escalation, multicenter study evaluating the safety, tolerability, and efficacy of StrataGraft skin tissue in promoting the healing of the deep partial-thickness…
- Conditions
- Skin Wound, Burns, Trauma-related Wound
- Trial name
- NCT01437852
- Testing
- StrataGraft Skin Tissue
- Where
- 6 sites in United States
- Volunteers
- 30 people
- Sponsor
- Stratatech, a Mallinckrodt Company
Pterygium
ICG Angiography in Amniotic Membrane Graft and Conjunctival Autograft After Pterygium Excision
To evaluate graft vascularization and compare the vascularization patterns of conjunctival autografts with amniotic membrane grafts to better understand the factors involved in pterygium recurrence.
- Trial name
- NCT00383825
- Testing
- Anterior segment indocyanine green angiography
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Baskent University
Genovarum
Results of Opening-wedge High Tibial Osteotomy Using Iliac Crest Allograft Compared to Iliac Crest Autograft
The purpose of this RCT is to determine the results of opening-wedge high tibial osteotomy in patients with genovarum deformity using iliac crest allograft compared to the results when using iliac crest autograft.
- Trial name
- NCT00595712
- Testing
- Iliac crest allograft, Iliac crest autograft
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Tehran University of Medical Sciences
Mantle Cell Lymphoma
Study of Mantle Cell Lymphoma Treatment by RiBVD
Study of First line mantle cell lymphoma treatment by Rituximab, Velcade, Bendamustine and Dexamethasone schema in patients older than 65 years or 18 to 65 years old who cannot or refuse receive conditioning regimen followed by…
- Trial name
- RIBVD (NCT01457144)
- Testing
- RiBVD
- Where
- France
- Volunteers
- 76 people
- Sponsor
- French Innovative Leukemia Organisation
Anterior Cruciate Ligament Injuries
The Use of Five-strand Hamstring Autograft to Increase the Graft Size in Anterior Cruciate Ligament Reconstruction - a Prospective Randomized Controlled Trial
Anterior cruciate ligament (ACL) reconstruction is one of most commonly performed orthopaedic surgeries. Several options for graft choice are available and autologous single bundle hamstring graft is most commonly used.
- Trial name
- NCT04531826
- Testing
- 5-strand hamstring graft preparation
- Volunteers
- 62 people
- Sponsor
- Hospital Authority, Hong Kong
Wound Dehiscence
Flipped Autograft for Treating Surgical Wound Dehiscence
This case report describes a novel technique for management of peri-implant wound dehiscence that involves using auto graft from the same surgical site to seal the dehiscence defect.
- Trial name
- NCT05513222
- Testing
- flipped autograft
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Non-Hodgkin's Lymphoma, Multiple Myeloma
Clinical And Economic Impact Of Upfront Plerixafor In Autologous Transplantation
This protocol will investigate the effectiveness of plerixafor in the up-front setting in avoiding a second round of mobilization and whether this translates into a clinical and economic benefit.
- Trial name
- NCT01339572
- Testing
- Plerixafor, Filgrastim
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Florida
Lymphoma, HIV
Autologous Transplant in HIV Patients (BMT CTN 0803)
This study is a Phase II, multicenter trial assessing overall survival after autologous hematopoietic stem cell transplantation using a BEAM transplant regimen (carmustine, etoposide, cytarabine, melphalan) in lymphoma patients…
- Trial name
- NCT01141712
- Testing
- Autologous transplant, BCNU, Etoposide
- Where
- 16 sites in United States
- Volunteers
- 43 people
- Sponsor
- Medical College of Wisconsin
Multiple Myeloma
Treatment of Newly Diagnosed Elderly Patients With Multiple Myeloma
In multiple myeloma, combination chemotherapy with melphalan plus prednisone has been used since the 1960s and is regarded as the standard of care in elderly patients.
- Trial name
- NCT00367185
- Testing
- Thalidomide
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Lille
Breast Cancer
Chemotherapy and Peripheral Stem Cell Transplantation Followed by Trastuzumab in Treating Women With Metastatic Breast Cancer
RATIONALE: Chemotherapy uses different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy…
- Trial name
- NCT00006123
- Testing
- trastuzumab, carboplatin, carmustine
- Where
- 2 sites in United States
- Sponsor
- Beth Israel Deaconess Medical Center
Diffuse Large B-Cell Lymphoma
Phase Ib/II Study of the Efficacy and Safety of the R-CMC544/R-GEMOX Combination in Diffuse Lage B-cell Lymphoma at First or Second Relapse
The purpose of this study is to determine the recommended dose of CMC544 administered in combination with rituximab (R-CMC544), and in alternance with rituximab, gemcitabine and oxaliplatin (R-GEMOX) in the first phase of the…
- Trial name
- NCT01562990
- Testing
- Rituximab, CMC544, Gemcitabine and Oxaliplatine
- Where
- 11 sites in Belgium, France
- Volunteers
- 11 people
- Sponsor
- The Lymphoma Academic Research Organisation
Multiple Myeloma, Non-Hodgkins Lymphoma
Study of the Best Timing for Plerixafor in Autologous Hematopoietic Stem Cell Collection
The purpose of this study is to determine whether it is safe and effective to collect peripheral blood hematopoietic stem cells 16 hours rather than the usual 11 hours after administration of plerixafor.
- Trial name
- NCT01042717
- Testing
- Plerixafor
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shi, Patricia, M.D.
Ovarian Function Insufficiency
Development of Ovarian Tissue Autograft in Order to Restore Ovarian Function
Ovarian cryopreservation is one of the available option for preserving fertility prior to potentially sterilizing treatments. In the absence of other techniques such as in vitro folliculogenesis or injection of isolated ovarian…
- Trial name
- DATOR (NCT02846064)
- Testing
- Autograft of cryopreserved ovarian tissue
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Eschar
Feasibility Study - The Place of Surgical Management by Fatty Autograft in Patients With Healed Pelvic Eschar. Interest in Secondary Prevention.
Autografting of fat cells is widely used in plastic surgery in breast reconstruction, burn scars, unsightly scars etc. It is known that the autografting of fat cells not only makes it possible to bring adipocytes, and thus to…
- Trial name
- FATSCAR (NCT03669406)
- Testing
- Autograft fat
- Where
- France
- Sponsor
- Rennes University Hospital
Lymphoma, Myeloma
Pedometer Activity Monitoring After ASCT
The trial assess the proportion of patients who resumed their professional activity within 100 days after ASCT (autologous stem cell Transplantation).
- Conditions
- Lymphoma, Myeloma, High-dose Chemotherapy, Autologous Stem Cell Transplantation
- Trial name
- PAMAL (NCT03238599)
- Testing
- Pedometer-based activity monitoring after ASCT
- Where
- Switzerland
- Volunteers
- 62 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Breast Cancer, Lymphoma
Biological Therapies Following Peripheral Stem Cell Transplantation in Treating Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, or Advanced Breast Cancer
RATIONALE: Interleukin-2 may stimulate a person's white blood cells to kill cancer cells. Filgrastim and stem cell factor may increase the number of immune cells found in bone marrow or peripheral blood and may help a person's…
- Trial name
- NCT00005993
- Testing
- aldesleukin, filgrastim, recombinant human stem cell factor
- Sponsor
- Masonic Cancer Center, University of Minnesota
Injury of Anterior Cruciate Ligament
Opioid Use in Single Shot Nerve Block vs Continuous Peripheral Nerve Infusion in Anterior Cruciate Ligament (ACL) Repair
Anterior cruciate ligament repair using hamstring autograft in children is a painful orthopedic procedure. The current practice to provide analgesia for this procedure include femoral continuous perineural infusion and femoral…
- Trial name
- NCT02075411
- Testing
- bupivacaine, continuous perineural infusion catheter
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Children's Hospital of Philadelphia
Rotator Cuff Tears
Results of Arthroscopic Massive Rotator Cuff Tears Repair With or Without Using Long Head of Biceps Tendon
The Goal of this clinical trial is to asses the function of arthroscopic repair with or without superior capsular augmentation using biceps tendon .
- Trial name
- NCT05817071
- Testing
- Arthroscopic massive rotator cuff repair, Arthroscopic massive rotator cuff repair with superior capsular augmentation using the long head of biceps tendon
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Rupture of the Anterior Cruciate Ligament With Instability of the Knee Joint
Hamstrings Autograft Versus Tibialis Allograft for Reconstruction of Anterior Cruciate Ligament
Patients suffering from a rupture of the anterior cruciate ligament (ACL) with instability of the knee joint are treated with an operative ACL-reconstruction: one group of patients with a reconstruction with an autograft tendon…
- Trial name
- NCT00510848
- Testing
- autograft tendon, allograft tendon
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University Hospital, Ghent