Clinical trials: Axial Spondyloarthritis
Rheumatoid Arthritis (RA, Ankylosing Spondylitis
Skin Autofluorescence Assessment of Advanced Glycation End Products in Rheumatic Diseases
Rheumatic diseases are chronic inflammatory conditions that can lead to long-term tissue damage and increased cardiovascular and metabolic risk.
- Conditions
- Rheumatoid Arthritis (RA, Ankylosing Spondylitis, Psoriatic Arthritis, Reactive Arthritis (ReA)
- Trial name
- NCT07329556
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Bursa City Hospital
Rheumatoid Arthritis, Arthritis, Psoriatic
Golimumab Safety and Surveillance Program Using the Ingenix NHI Database
The participants included in this observational study will be drawn from a research database containing claims and enrollment data for members of a large, geographically diverse US health plan.The objective of this study is to…
- Conditions
- Rheumatoid Arthritis, Arthritis, Psoriatic, Ankylosing Spondylitis
- Trial name
- NCT01081717
- Testing
- systemic non-biological treatments, anti-TNF biologics, golimumab
- Volunteers
- 1,064 people
- Sponsor
- Janssen Biotech, Inc.
Ankylosing Spondylitis (AS), Back Pain
Efficacy of the Erector Spinae Plane Block for Persistent Back Pain in Patients With Ankylosing Spondylitis
Despite adequate control of disease activity with standard medical therapies, there remains an ongoing need for complementary and interventional approaches for the management of persistent back pain in patients with ankylosing…
- Conditions
- Ankylosing Spondylitis (AS), Back Pain, ESPB, Regional Anesthesia
- Trial name
- NCT07633730
- Testing
- Erector spinae plane block(ESBP)
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Marmara University
Axial Spondyloarthritis
Efficacy and Safety of SCT650C in Participants With Axial Spondyloarthritis
The purpose of this study is to assess efficacy, safety, pharmacokinetics and immunogenicity of subcutaneous SCT650C in patients with Axial Spondyloarthritis
- Trial name
- NCT06197009
- Testing
- SCT650C
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Sinocelltech Ltd.
Ankylosing Spondylitis
Clinical Trial of Osteoporosis in Ankylosing Spondylitis
This is an observational study aiming to study the prevalence and risk factors for osteoporosis and vertebral fractures in patients with ankylosing spondylitis attending three Rheumatology clinics in Western Sweden.
- Trial name
- NCT00858819
- Where
- Sweden
- Volunteers
- 250 people
- Sponsor
- Göteborg University
Epidural Block in Axial Spondyloarthritis
Ultrasound Guided Epidural Block in Axial SPA
Study Design: A randomized, prospective, pilot, controlled trial. Setting: Rheumatology and rehabilitation department Minia University and Sohag University Objectives: To evaluate the effectiveness of caudal epidural injections…
- Trial name
- NCT04143165
- Testing
- Epidural block with lidocaine and triamcinilone
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Sohag University
Axial Spondyloarthritis, Ankylosing Spondylitis
Vilamakitug in Spondyloarthritis Placebo-controlled Investigation for Efficacy
The goal of this clinical trial is to find out if the study drug will work as a new therapy for axSpA patients. This study is placebo-controlled, and evaluates if study drug can treat symptoms of axSpA, including global disease…
- Conditions
- Axial Spondyloarthritis, Ankylosing Spondylitis, r-axSpA, Nr-axSpA
- Trial name
- V-SPINE (NCT06526377)
- Testing
- vilamakitug
- Volunteers
- 150 people
- Sponsor
- XBiotech, Inc.
Ankylosing Spondylitis, Rheumatoid Arthritis
Quality of Life in Chronic Arthritis
Chronic joint complaints are prevalent in clinical practice. If chronic arthritis such as rheumatoid arthritis (RA) or ankylosing spondylitis (AS) is not adequately controlled, it can not only affect patient's working ability but…
- Trial name
- NCT01357018
- Where
- Taiwan
- Volunteers
- 139 people
- Sponsor
- Far Eastern Memorial Hospital
Ankylosing Spondylitis
Work Productivity in Active Ankylosing Spondylitis (AS) Patients Treated With Enbrel.
Patients with Ankylosing spondylitis more frequently discontinue work. This study measures the impact of Enbrel on work participation.
- Trial name
- AS@WORK (NCT01421303)
- Testing
- Enbrel
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Pfizer
Rheumatoid Arthritis, Inflammatory Arthritis
Safety and Effectiveness of Live Zoster Vaccine in Anti-Tumor Necrosis Factor (TNF) Users (VERVE Trial)
The VaricElla zosteR VaccinE (VERVE) trial evaluates the safety and effectiveness of the Herpes zoster (HZ) vaccine for shingles, Zostavax, in patients over 50 years old with arthritis and other diseases who are using anti-tumor…
- Conditions
- Rheumatoid Arthritis, Inflammatory Arthritis, Arthritis, Psoriatic Arthritis
- Trial name
- NCT02538341
- Testing
- Herpes Zoster (HZ) Vaccine
- Where
- 34 sites in United States
- Volunteers
- 617 people
- Sponsor
- University of Alabama at Birmingham
Tuberculosis
A Real-world Study of Tuberculosis Incidence in AS, PsA, or PsO Patients Treated With Secukinumab in Brazil
This was a retrospective observational study that relied on data extracted from patient's chart review at the participating centers.
- Trial name
- ToBeReal (NCT06715254)
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Novartis Pharmaceuticals
Axial Spondyloarthritis
Novel MRI ANd Biomarkers in GOlimumab-treated Patients With Axial Spondyloarthritis
The study investigates different criteria for remission based on MRI and circulating biomarkers for inflammation, cartilage, connective tissue and bone turnover in patients with axial spondyloarthritis treated with Golimumab.
- Trial name
- MANGO (NCT02011386)
- Testing
- Treatment
- Where
- 6 sites in Denmark
- Volunteers
- 53 people
- Sponsor
- Professor Mikkel Østergaard
Axial Spondyloarthrithis, Inflammatory Diseases
EXercise Therapy in Axial SpA, Inflammation and Biologic Therapy (ExTASI-B)
The goal of this randomised controlled trial study is to investigate whether exercise (brisk walking, equal to 13 on a rating of perceived exertion scale; somewhat hard) can be used as an adjuvant therapy for people living with…
- Conditions
- Axial Spondyloarthrithis, Inflammatory Diseases, Arthritis
- Trial name
- ExTASI-B (NCT06669702)
- Testing
- 12-week home based exercise, Routine care
- Where
- 2 sites in United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Healthy Volunteers
A Pilot Open-Label Crossover Bioavailability Study of Celecoxib in Healthy Volunteers
A pharmacokinetic study in healthy volunteers to determine the relative bioavailability of three formulations of celecoxib to the approved formulation.
- Trial name
- NCT00813241
- Testing
- celecoxib reference formulation, celecoxib test formulation A1, celecoxib test formulation B2
- Where
- Singapore
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Rheumatoid Arthritis, Ankylosing Spondylitis
Employment and Arthritis: Making it Work
The investigators plan to conduct a randomized controlled trial to evaluate the effectiveness and the cost effectiveness of an on-line eLearning program (entitled Employment and Arthritis: Making it Work) designed to help people…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Lupus Erythematosus, Systemic, Psoriatic Arthritis
- Trial name
- MIW (NCT01852851)
- Testing
- Employment and Arthritis: Making it Work
- Where
- Canada
- Volunteers
- 528 people
- Sponsor
- University of British Columbia
Autoimmune Diseases, Ulcerative Colitis
A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease
The most clinically meaningful way to discover new targets of T cells in autoimmune diseases is to study the tissues of patients with active autoimmune disease mediated organ inflammation.
- Conditions
- Autoimmune Diseases, Ulcerative Colitis, Multiple Sclerosis, Scleroderma
- Trial name
- NCT06587828
- Testing
- Companion blood samples with procedure
- Where
- 11 sites in United States
- Volunteers
- 238 people
- Sponsor
- TScan Therapeutics, Inc.
Axial Spondyloarthritis, Crohn Disease
MRE as a Screening Tool for axSpA in IBD
This study aims to assess the effectiveness (specificity and sensitivity) of using magnetic resonance enterography (MRE) as a screening tool for axial spondyloarthritis (axSpA) in patients with Crohns disease.
- Trial name
- ProSpA-CD (NCT03817983)
- Testing
- MRE review for evidence of axSpA in SIJs, Clinical assessment and dedicated MRI of the spine and pelvis
- Where
- United Kingdom
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Rheumatoid Arthritis, Polyarthritis
Construct Validity and Responsiveness of EQ-5D-3L in Patients With Rheumatic Disease
The aim of this study is to investigate the construct validity (convergent and known-groups) and responsiveness of EQ-5D-3L in patients with rheumatoid arthritis, polyarthritis, psoriatic arthritis, and ankylosing spondylitis.
- Conditions
- Rheumatoid Arthritis, Polyarthritis, Psoriatic Arthritis, Ankylosing Spondylitis
- Trial name
- NCT06568029
- Testing
- Questionnaire
- Where
- Sweden
- Volunteers
- 77,651 people
- Sponsor
- Karolinska Institutet
Spondylitis, Ankylosing
Remicade Safety Line (Ankylosing Spondylitis)(Study P03275)(COMPLETED)
This observational study is in line with the German educational plan with the aim to implement a tool to increase and monitor the awareness of tuberculosis screening and to reinforce the patient eligibility for a treatment with…
- Trial name
- NCT00818168
- Testing
- Infliximab
- Volunteers
- 320 people
- Sponsor
- Merck Sharp & Dohme LLC
Ankylosing Spondylitis
Phase II Pilot Study of Olsalazine for Ankylosing Spondylitis
OBJECTIVES: I. Assess the safety and efficacy of olsalazine, a dimer of 5-aminosalicylic acid, in men with ankylosing spondylitis unresponsive to nonsteroidal anti-inflammatory drugs and physiotherapy.
- Trial name
- NCT00004288
- Testing
- olsalazine
- Volunteers
- 4 people
- Sponsor
- National Center for Research Resources (NCRR)