Clinical trials: Axial Spondyloarthritis
Crohn Disease, Ulcerative Colitis
A Study of the Real-world Use of an Adalimumab Biosimilar and Evaluation of Nutritional Status on the Therapeutic Response
The aim of the study is to describe the real-world profile of patients treated with adalimumab FK in gastroenterology, dermatology or rheumatology in order to evaluate in this population the predictive factors of therapeutic…
- Conditions
- Crohn Disease, Ulcerative Colitis, Psoriasis, Ankylosing Spondylitis
- Trial name
- OPALE (NCT05051943)
- Where
- France
- Volunteers
- 754 people
- Sponsor
- Fresenius Kabi
Non-radiographic Axial Spondyloarthritis
A Study of Secukinumab to Evaluate Maintenance of Response in Participants With Non-radiographic Axial Spondyloarthritis Who Achieved Remission
This study will establish whether prolonged chronic dosing with secukinumab is needed in participants with Non-radiographic axial spondyloarthritis, (nr-axSpA) who have achieved remission.
- Trial name
- NCT05622708
- Testing
- Secukinumab
- Where
- 61 sites in Belgium, Brazil and 16 more
- Volunteers
- 240 people
- Sponsor
- Novartis Pharmaceuticals
Ankylosing Spondylitis
A Phase III Study Evaluate the Efficacy and Safety of BAT1406 and Humira
A Phase III Study Evaluate the Efficacy and Safety of BAT1406 and Humira
- Trial name
- NCT04135508
- Testing
- BAT1406, Humira
- Volunteers
- 554 people
- Sponsor
- Bio-Thera Solutions
Rheumatoid Arthritis, Ankylosing Spondylitis
Assessment of Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, Plaque Psoriasis, Crohn's Disease and Ulcerative Colitis Patients´ Adherence Attitudes to Maintenance Therapy With a Scheduled Adalimumab Treatment in Routine Clinical Practice
The purpose of this non-interventional, multicenter, post-marketing observational study (PMOS) was to assess rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), plaque psoriasis (PS), Crohn's…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis, Crohn´s Disease
- Trial name
- Adherence (NCT01768858)
- Testing
- Adalimumab
- Volunteers
- 96 people
- Sponsor
- AbbVie
Ankylosing Spondylitis
A Molecule Basic Study of Early Warning for New Pathogenic Risk of Ankylosing Spondylitis
The investigators will recruit active ankylosing spondylitis patients for injection treatment of Human Mesenchymal Stem Cells (a prospective, open-label, masculine medicine controlled(NSAIDs), clinical trial), and collect their…
- Trial name
- NCT01709656
- Testing
- MSC, "celecoxib", "Celebrex®"
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Sun Yat-sen University
Nr-axial Spondyloarthritis, Non-Radiographical Axial Spondyloarthritis
Efficacy and Safety of Xeligekimab in the Treatment of Non-Radiographic Axial Spondyloarthritis
Subjects who have signed the informed consent form will undergo examinations and assessments according to the inclusion/exclusion criteria specified in the trial protocol.
- Trial name
- NCT07339566
- Testing
- Xeligekimab injection
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Lingli Dong
Axial Spondyloarthritis
The Efficacy of Fecal Microbiota Transplatation on Axial Spondyloarthritis Patients Resistant to Conventional Treatment
Current pharmacological management of inflammatory rheumatism and in particular axial SpA remains imperfect. Only 50% of patients respond to the most effective biotherapies, and many of them are only partially relieved.
- Trial name
- FMT-SpA (NCT05654753)
- Testing
- active FMT
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Inflammatory Bowel Disease (IBD), Spondylarthropathies
Prevelance of Axial Spondylosis Arthritis in Inflammatory Bowel Disease and Its RESPONSE to Tumour Necrosis Factor (TNF) Inhibitors Treatment in Assiut University Hospital
Prevelance of axial spondylosis arthritis in inflammatory bowel disease and its RESPONSE to tumour necrosis factor (TNF) inhibitors TREATMENT
- Conditions
- Inflammatory Bowel Disease (IBD), Spondylarthropathies, TNF-alpha Inhibitors
- Trial name
- NCT06601595
- Testing
- TNF inhibitors, conventional ibd medical treatment
- Volunteers
- 100 people
- Sponsor
- Mohamed Nasr
Ankylosing Spondylitis
Extension Study for Long Term Evaluation of SAR153191 (REGN88) in Patients With Ankylosing Spondylitis
Primary Objective: To assess the long term safety of Sarilumab (SAR153191/REGN88) in participants with ankylosing spondylitis (AS) Secondary Objective: To assess the long term efficacy of Sarilumab (SAR153191/REGN88) in…
- Trial name
- SUSTAIN (NCT01118728)
- Testing
- Sarilumab
- Where
- 12 sites in United States, Australia and 10 more
- Volunteers
- 223 people
- Sponsor
- Sanofi
Back Pain, Spondylitis, Ankylosing
Biopsychosocial Exploration of Pain Profiles in Inflammatory and Chronic Non-specific Axial Low Back Pain
The biopsychosocial model is well established in chronic low back pain (CLBP) research. Nevertheless, researchers to date have overlooked the biopsychosocial aspects of Inflammatory Low Back pain (ILBP).
- Conditions
- Back Pain, Spondylitis, Ankylosing, Low Back Pain
- Trial name
- NCT02704845
- Where
- 3 sites in Ireland
- Volunteers
- 58 people
- Sponsor
- University of Dublin, Trinity College
Axial Spondyloarthritis
Effects of Nonsteroidal Anti-Inflammatory Drugs in Recurrence of Spondyloarthritis Patients After Remission
The multicenter, randomized controlled trial is to investigate and evaluate the effect of NSAIDs therapy on recurrence in patients with axial spondyloarthritis;
- Trial name
- NCT03425812
- Testing
- To withdraw NSAIDs therapy, To continue NSAIDs therapy
- Where
- China
- Volunteers
- 140 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Rheumatoid Arthritis, Inflammatory Bowel Disease
Incidence of Hospitalizations for Serious Infections in Patients Receiving Biologic Anti-Inflammatories for Rheumatologic, Psoriatic, and Gastrointestinal Conditions: A Descriptive Analysis
Purpose: With the existing biologic anti-inflammatory product patents expiring and the FDA approval of new biosimilar and innovator biologics, patients with rheumatologic (RA), psoriatic (PsO-PsA-AS), and gastrointestinal (GI)…
- Conditions
- Rheumatoid Arthritis, Inflammatory Bowel Disease, Psoriasis, Psoriatic Arthritis
- Trial name
- NCT02922192
- Testing
- TNF-α antagonists, non-TNFs, DMARD non-biologics
- Volunteers
- 90,360 people
- Sponsor
- Biologics & Biosimilars Collective Intelligence Consortium
Spondyloarthropathies, Ankylosing Spondylitis
Efficacy of Pain Neuroscience Education and Physiotherapy in Patients Diagnosed with Spondyloarthritis
Spondyloarthritis, notably ankylosing spondylitis (AS), represents a chronic rheumatic condition typified by persistent back pain and stiffness.
- Trial name
- NCT06369324
- Testing
- Pain education, Exercise supervised by external focus, Therapy by means of electrical stimulation (electro-massage)
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Universidad de Extremadura
Ankylosing Spondylitis, Yoga
The Effects of Tele-Yoga in Ankylosing Spondylitis Patients
The aim of this study is to investigate the effect of tele-yoga on functional level, disease activity, spinal mobility, balance, aerobic capacity, sleep quality, anxiety, depression, stress, mindfulness and quality of life in…
- Trial name
- NCT04803383
- Testing
- Tele-yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dokuz Eylul University
Spondyloarthritis
Value of Whole-body SPECT-CT CzT-based Camera (VERITON-CT) in the Assessment of Chronic Inflammatory Rheumatism With Axial Involvement
The diagnosis of chronic inflammatory rheumatism with axial involvement is not always easy, and is fraught with difficulties : radiological sacroiliitis is not an early sign of spondyloarthritis and the delay in detecting…
- Trial name
- ASOCE (NCT06198361)
- Where
- France
- Volunteers
- 47 people
- Sponsor
- Central Hospital, Nancy, France
Spondyloarthritis (SpA), Ankylosing Spondylitis (AS)
Effect and Safety of Benzathine Penicillin Combined With Etanercept on Spondyloarthritis
The purpose of the study is to verify the clinical feasibility of Benzathine penicillin (BPG) /Etanercept (ETN) combination regimen in patients with spondyloarthritis (SpA) and at the same time compare Benzathine penicillin…
- Trial name
- NCT06707194
- Testing
- Etanercept, Benzathine Penicillin
- Where
- 6 sites in China
- Volunteers
- 340 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Healthy Volunteers
A Pilot Open-Label Crossover Bioavailability Study of Celecoxib in Healthy Volunteers
A pharmacokinetic study in healthy volunteers to determine the relative bioavailability of three formulations of celecoxib to the approved formulation.
- Trial name
- NCT00813241
- Testing
- celecoxib reference formulation, celecoxib test formulation A1, celecoxib test formulation B2
- Where
- Singapore
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Rheumatoid Diseases, Rheumatoid Arthritis
Post-Marketing Use Of CT-P13 (Infliximab) For Standard Of Care Treatment Of Rheumatoid Diseases Who Are Naïve To Biologics Or Switched From Remicade
To assess persistence of CT-P13 in patients with Rheumatoid Diseases (Rheumatoid arthritis [RA], ankylosing spondylitis [AS], and psoriatic arthritis [PsA]) who are naïve to biologics or are switching from stable Remicade to…
- Conditions
- Rheumatoid Diseases, Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis
- Trial name
- PERSIST (NCT02605642)
- Testing
- CT-P13
- Where
- 38 sites in Bulgaria, Canada and 5 more
- Volunteers
- 351 people
- Sponsor
- Pfizer
Ankylosing Spondylitis
Exercise Therapy Program in Ankylosing Spondylitis Patients
Mobility exercises are used in Ankylosing Spondylitis (AS) patients to preserve and restore axial mobility, but there are no data regarding a specific rehabilitation program that includes flexibility alone and its association…
- Trial name
- NCT01690273
- Testing
- mobility exercise, mobility and elastic resistance exercise
- Where
- Brazil
- Volunteers
- 55 people
- Sponsor
- University of Sao Paulo
Axial Spondyloarthritis
The Impact of Simulated Forest Immersion Therapy on Pain and Anxiety in Patients Axial Spondyloarthritis (axSpA)
The purpose of the study is to learn about the ease of using a humidified fragrant citrus forest oil, along with a virtual simulation of a forest environment (i.e., with sights and sounds of nature using a personal tablet Surface…
- Trial name
- NCT06072859
- Testing
- Humidified Forest Oils, Forest oils and audio-visual forest exposure
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Oregon Health and Science University