Clinical trials: Axial Spondyloarthritis
Axial Spondyloarthritis (AxSpA), Axial Spondyloarthritis, Non-Radiographic
The REFLECT Study- Flares in axSpA
Axial spondyloarthritis (axSpA) is a long-term inflammatory condition that affects the spine and sacroiliac joints. People living with axSpA often experience periods when their symptoms suddenly worsen, known as disease "flares."…
- Conditions
- Axial Spondyloarthritis (AxSpA), Axial Spondyloarthritis, Non-Radiographic, Axial Spondyloarthritis, Radiographic, Axial Spondylarthritis (r-axSpA)
- Trial name
- REFLECT (NCT07688174)
- Where
- 2 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- Royal United Hospitals Bath NHS Foundation Trust
Ankylosing Spondylitis
Comparative Clinical Trial to Evaluate Efficacy and Safety of BCD-055 and Remicade® in Patients With Ankylosing Spondylitis
BCD-055-2 is international multi-center comparative double-blind randomized clinical trial to evaluate efficacy and safety of BCD-055 (JSC "BIOCAD", Russia) and Remicade® in patients with ankylosing spondylitis.
- Trial name
- NCT02762812
- Testing
- BCD-055, Remicade®
- Where
- Russia
- Volunteers
- 199 people
- Sponsor
- Biocad
Ankylosing Spondylitis, Spondylitis, Ankylosing
The Effect of Mobile Application on Subcutaneous Anti-TNF Drug Administration:Ankylosing Spondylitis Patients
This study was carried out to develop an android mobile application for the subcutaneous (SC) anti-TNF drug administration of ankylosing spondylitis patients and to evaluate its effect on drug administration.
- Trial name
- NCT04301128
- Testing
- Experimental, control
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Eskisehir Osmangazi University
Ankylosing Spondylitis, Spondyloarthritis
Treat-to-target Strategy in Ankylosing Spondylitis Using Etanercept and Conventional Synthetic DMARDs
This study evaluates clinical responses and cost-effectiveness of using etanercept (ETN) and conventional synthetic Disease modifying anti-rheumatic drugs (csDMARDs) with treat-to-target strategy in ankylosing spondylitis…
- Trial name
- NCT04077957
- Testing
- Methotrexate, Sulfasalazine, Hydroxychloroquine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Sjögren's Syndrome, Systemic Lupus Erythematosus
Objective Measurement Methods for Autoimmune Disease and Dry Eye Syndrome
To explore the association among TCM pattern, TCM tongue diagnosis and TCM pulse diagnosis for Autoimmune disease and Dry eye syndrome
- Conditions
- Sjögren's Syndrome, Systemic Lupus Erythematosus, Rheumatoid Arthritis, Systemic Sclerosis
- Trial name
- NCT03937271
- Testing
- Traditional Chinese Medicine pattern, Traditional Chinese Medicine tongue diagnosis, Traditional Chinese Medicine pulse diagnosis
- Where
- Taiwan
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Giant Cell Arteritis (GCA), Spondylarthritis
Study of the Association Between Sacroiliitis/Axial Spondylarthritis and Giant Cell Arteritis/ Polymyalgia Rheumatica
The purpose of the study is to recruit as many patients as possible presenting with sacroiliitis or authentic axial spondylarthritis and giant cell arteritis.
- Conditions
- Giant Cell Arteritis (GCA), Spondylarthritis, Polymyalgia Rheumatica
- Trial name
- SAGE PPR (NCT07394478)
- Testing
- Description of population
- Where
- 2 sites in France
- Volunteers
- 10 people
- Sponsor
- Hôpital NOVO
Rheumatoid Arthritis, Ankylosing Spondylitis
Frequency and Complications of Major Orthopedic Procedures in Medicare Beneficiaries
Background: Orthopedic procedures are common in the United States. These include joint replacement and spine surgeries. Researchers want to study data about these procedures over time.
- Trial name
- NCT02281747
- Where
- United States
- Volunteers
- 521,292 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Axial Spondyloarthritis and Ankylosing Spondylitis
Effects of Land- and Water-Based Exercise in Axial Spondyloarthritis
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by pain, morning stiffness, restricted spinal mobility, and systemic manifestations.
- Trial name
- NCT07833033
- Testing
- Land-Based Combined Exercise Program, Aquatic Combined Exercise Program, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Izmir University of Economics
Anklyosing Spondylitis
CALLY Index and Disease Activity in Ankylosing Spondylitis
This retrospective cross-sectional observational study aims to evaluate the association between the C-reactive protein-albumin-lymphocyte (CALLY) index and disease activity and functional status in patients with ankylosing…
- Trial name
- NCT07509463
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Bursa City Hospital
Ankylosing Spondylitis
The Impacts of Gluten-free Diet in Patients With Ankylosing Spondylitis
Subclinical intestinal inflammation and intestinal permeability have been reported in patients with ankylosing spondylitis. Gluten is one of the main triggers of zonulin releaseand gluten intake may contribute to the development…
- Trial name
- NCT07166874
- Testing
- Gluten Free Diet
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Saglik Bilimleri Universitesi
Axial Spondylarthritis (axSpA)
Initial Standardized Global Review in Axial Spondyloarthritis
This study will be a pragmatic, cluster-randomized, controlled study with two parallel arms ( 'intervention' and 'usual care' (UC) arms) of one year duration.
- Trial name
- REVINSPA (NCT07141017)
- Testing
- Initial standardized global review
- Where
- 21 sites in France
- Volunteers
- 154 people
- Sponsor
- Association de Recherche Clinique en Rhumatologie
Autoimmune Diseases
Role of LILRA3 in Ankylosing Spondylitis and Axial Psoriatic Patients
1. To evaluate the frequency of LILRA3 in Ankylosing spondylitis and Axial psoriatic arthritis patients. 2. To investigate the association of LILRA3 with Ankylosing spondylitis and Axial psoriatic arthritis disease activity and…
- Trial name
- NCT05915676
- Testing
- Leukocyte Immunoglobulin-like receptors A3
- Volunteers
- 100 people
- Sponsor
- Assiut University
Axial Spondyloarthritis
The Effect of Exercise on Disease Activity and Cardiovascular Risk for Patients With Axial SpondyloArthritis
The overall aim of this multicenter randomised controlled trial (RCT) is to investigate if exercise can modify the disease course and prevent comorbidity in patient with spondyloarthritis (SpA).
- Trial name
- ESpA (NCT02356874)
- Testing
- Exercise
- Where
- 4 sites in Norway, Sweden
- Volunteers
- 100 people
- Sponsor
- Diakonhjemmet Hospital
Spondylarthritis
Assessment of Whole Body Cryotherapy in Treatment of Active Axial Spondylarthritis
Whole body cryotherpy (WBC) is a well-tolerated procedure that implies patients' exposition at a temperature of approximately -110 degrees.
- Trial name
- NCT02473315
- Testing
- cryotherapy
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Ankylosing Spondylitis
An Open-Label Multicentre Long-Term Extension Study of Etanercept for Ankylosing Spondylitis
This study is an extension trial of 0881A3-312-EU and is designed to provide information on the safety and efficacy of etanercept in patients with ankylosing spondylitis for up to 3 additional years.
- Trial name
- NCT00444340
- Testing
- Enbrel (Etanercept)
- Volunteers
- 70 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Ankylosing Spondylitis
International Multicenter Comparative Randomized Placebo-controlled Clinical Study of Efficacy and Safety of BCD-085 in Patients With Ankylosing Spondylitis
BCD-085-5 is an International, Multicenter, Randomized, Double-blind, Placebo-controlled Clinical Study of the Efficacy and Safety of BCD-085. BCD-085 is a monoclonal antibody to interleukin 17.
- Trial name
- NCT03447704
- Testing
- BCD-085
- Where
- 7 sites in Russia
- Volunteers
- 228 people
- Sponsor
- Biocad
Axial Spondyloarthritis
A Study Evaluating the Effect of Filgotinib in Participants With Active Axial Spondyloarthritis
This study is comparing 200 milligrams (mg) of filgotinib a day with a placebo to see if filgotinib helps to treat Axial Spondyloarthritis (axSpA) and is safe to use.
- Trial name
- OLINGUITO (NCT05785611)
- Testing
- Filgotinib
- Where
- 123 sites in Belgium, Bulgaria and 16 more
- Volunteers
- 495 people
- Sponsor
- Alfasigma S.p.A.
Rheumatic Disease
Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty
The purpose of this study is to assess the incidence of rheumatologic flares, changes in pain scores (VAS), changes in functional outcomes (PROMIS), wound complications, surgical site infections, and return trips to the operating…
- Trial name
- NCT07138898
- Testing
- Methotrexate, Sulfasalazine, Hydroxychloroquine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- NYU Langone Health
Comparative Efficacy and Safety of Thalidomide and Sulfasalazine in Moderate to Severe Ankylosing Spondylitis: A Real-World Study From Bangladesh, Condition ...Moderate to Severe Axial Spondyloarthopathy
Comparative Efficacy and Safety of Thalidomide and Sulfasalazine in Moderate to Severe Ankylosing Spondylitis: A Real-World Study From Bangladesh
the present study was conducted to determine the comparative efficacy and safety of thalidomide and SSZ in moderate to severe cases of ankylosing spondylitis in Bangladesh.
- Trial name
- NCT06985134
- Testing
- Comparative Efficacy and Safety of Thalidomide and Sulfasalazine in Moderate to Severe Ankylosing Spondylitis: A Real-World Study from Bangladesh
- Where
- Bangladesh
- Volunteers
- 93 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Crohn Disease, Ulcerative Colitis
Expanded Access to Upadacitinib
This is an expanded access program (EAP) for eligible participants. This program is designed to provide access to upadacitinib prior to approval by the local regulatory agency. Availability will depend on territory eligibility.
- Conditions
- Crohn Disease, Ulcerative Colitis, Idiopathic Arthritis (Including sJIA, pJIA, or JPsA), Atopic Dermatitis
- Trial name
- NCT04159597
- Testing
- Upadacitinib
- Sponsor
- AbbVie