Clinical trials: Axial Spondyloarthritis
Ankylosing Spondylitis
The Effects of Postural Changes on Plantar Pressure in Patients With Ankylosing Spondylitis
Ankylosing Spondlitis (AS) is a chronic, rheumatic disease. Foot and ankle involvement may stem from both postural changes in patients seen spinal deformity with the progress of the disease and enthesitis.
- Trial name
- NCT04820725
- Testing
- Plantar pressure and gait
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gazi University
Early Ankylosing Spondylitis
Clinical Study of Tripterygium Capsule to Treat Early Ankylosing Spondylitis
This study is a 12-week, randomized, placebo and positive drug controlled clinical trial to investigate whether tripterygium capsule is effective and safe in treating patients with ankylosing spondylitis.
- Trial name
- NCT00889694
- Testing
- Tripterygium, Sulfasalazine
- Volunteers
- 80 people
- Sponsor
- Sun Yat-sen University
Anklyosing Spondylitis, Telerehabilitation
Effectiveness of Telerehabilitation in Ankylosing Spondylitis
Purpose of the study: Ankylosing spondylitis (AS) is a chronic disease that affects the spine and joints, causing pain, stiffness, fatigue, and reduced quality of life.
- Trial name
- NCT07503327
- Testing
- Synchronous Telerehabilitation Exercise Program, Asynchronous Telerehabilitation Exercise Program, Brochure Program
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Inonu University
Rheumatoid Arthritis, Ankylosing Spondylitis
99m-Technetium- Glucosamine in Arthritis
Preliminary data following a pilot study from our institution confirms the ability of 99mTc-glucosamine (99mTc-ECDG) to differentiate between active, subclinical and quiescent disease in patients with rheumatoid arthritis…
- Trial name
- NCT01789151
- Testing
- Technetium labelled glucosamine
- Where
- Australia
- Sponsor
- University of Sydney
Spondylitis, Ankylosing
A Study Investigating an Exercise and Education Programme for Individuals With Ankylosing Spondylitis
Ankylosing Spondylitis(AS) is a chronic, inflammatory, rheumatic disease (Khan, 2002). AS is associated with increased work disability and use of healthcare resources (Ward et al, 2008).
- Trial name
- NCT00764686
- Testing
- Exercise and Education
- Where
- Ireland
- Volunteers
- 18 people
- Sponsor
- University College Dublin
Ankylosing Spondylitis
A Study to Evaluate the Long Term Safety and Efficacy of Bimekizumab in Subjects With Ankylosing Spondylitis
This is a study to assess the long term safety and tolerability of bimekizumab in subjects with ankylosing spondylitis
- Trial name
- BE AGILE 2 (NCT03355573)
- Testing
- Bimekizumab
- Where
- 50 sites in United States, Bulgaria and 8 more
- Volunteers
- 255 people
- Sponsor
- UCB Biopharma SRL
Spondyloarthritis
Study of Jitongning Tablet to Treat Spondyloarthritis
This study is to investigate the efficacy and safety of Jitongning Tablet in improving joint function and pain symptoms in active axial spondyloarthritis (SpA) patients and to explore the optimal dosage.
- Trial name
- NCT03932019
- Testing
- Jitongning tablet(High-dose ), Jitongning tablet(Low-dose )
- Where
- 11 sites in China
- Volunteers
- 238 people
- Sponsor
- Tasly Pharmaceutical Group Co., Ltd
Spondylitis, Ankylosing
Extension in AS: Sustainability of Benefits, Safety and Tolerability
This 3-year extension study aims at making available the treatment with secukinumab in prefilled syringes (PFS) to patients with ankylosing spondylitis who took part in phase III study CAIN457F2305, defined as "core study", as…
- Trial name
- MEASURE 1 ext (NCT01863732)
- Testing
- Secukinumab
- Where
- 56 sites in United States, Belgium and 12 more
- Volunteers
- 274 people
- Sponsor
- Novartis Pharmaceuticals
Ankylosing Spondylitis
An Open-Label Study to Evaluate the Response to Adalimumab in Patients With Active Ankylosing Spondylitis Who Have Failed Standard Therapy or TNF-Alpha Inhibitors (RHAPSODY)
Due to the rigor of the clinical development program of adalimumab for the indication of AS, the population of subjects with active AS that could enroll in previous phase 3 studies was limited.
- Trial name
- RHAPSODY (NCT00478660)
- Testing
- adalimumab (Humira)
- Where
- 205 sites in Austria, Belgium and 13 more
- Volunteers
- 1,250 people
- Sponsor
- Abbott
Inflammatory Bowel Disease (IBD)
SNU IBD Cohort Study : Searching for Characterization of High Risk Populations for Developing Inflammatory Bowel Disease
The goal of this observational study is to investigate characteristics of individuals at high risk for developing Inflammatory Bowel Disease (IBD) in order to identify risk factors associated with its incidence.
- Trial name
- SNU PREVENT (NCT07011979)
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Seoul National University Hospital
Ankylosing Spondylitis
ABY-035 in the Treatment of Subjects With Ankylosing Spondylitis
ABY-035-204 is a clinical study to assess the efficacy of IL-17 blocker ABY-035 in ankylosing spondylitis(AS). The primary objective is to estimate the relationship between different dose regimens of ABY-035 and clinical response…
- Trial name
- NCT04795141
- Testing
- ABY-035
- Where
- 47 sites in United States, China and 1 more
- Volunteers
- 25 people
- Sponsor
- Inmagene LLC
Axial and Peripheral Spondyloarthritis, Rheumatoid Arthritis
Scintigraphic Detection of the Biodistribution of Tumor Necrosis Factor With a Radiolabeled Anti-TNFα in Patients With Active Rheumatoid Arthritis and Active Axial and Peripheral Spondyloarthritis
In this open-label monocentric explorative pilot trial the objective is to show the biodistribution of TNFα by administration of radiolabeled anti-TNFα in patients with active rheumatoid arthritis and spondylarthropathy.
- Trial name
- SCINTRA (NCT01590966)
- Testing
- administration of Cimzia®, Immunoscintigraphy with radiolabeled Cimzia®.
- Where
- Belgium
- Volunteers
- 41 people
- Sponsor
- University Hospital, Ghent
Spondyloarthropathy
Identification of Serum Level of Glutathione Peroxidase 4
Analysis of the level of glutathione peroxidase 4 (GPX4) in ankylosing spondylitis and axial psoriatic arthritis patients. The association of glutathione peroxidase 4 (GPX4) with disease activity and severity in ankylosing…
- Trial name
- NCT06554392
- Testing
- Blood sample
- Volunteers
- 85 people
- Sponsor
- Assiut University
Ankylosing Spondylitis, Psoriasis
Evaluation of Serum IL-41 Level in Patients With Ankylosing Spondylitis and Psoriatic Arthritis
Psoriatic arthritis (PsA) and ankylosing spondylitis (AS) are chronic inflammatory diseases within the spectrum of spondyloarthritis, characterized by immune-mediated inflammation and progressive functional impairment.
- Trial name
- NCT07648836
- Testing
- IL 41
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ankylosing Spondylitis
Extension Study for Long Term Evaluation of SAR153191 (REGN88) in Patients With Ankylosing Spondylitis
Primary Objective: To assess the long term safety of Sarilumab (SAR153191/REGN88) in participants with ankylosing spondylitis (AS) Secondary Objective: To assess the long term efficacy of Sarilumab (SAR153191/REGN88) in…
- Trial name
- SUSTAIN (NCT01118728)
- Testing
- Sarilumab
- Where
- 12 sites in United States, Australia and 10 more
- Volunteers
- 223 people
- Sponsor
- Sanofi
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Rheumatoid Arthritis, Psoriatic Arthritis
A Study to Assess the Safety and Effectiveness of Golimumab in Filipino Patients With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis
The purpose of this study is to assess the safety and effectiveness of golimumab for the treatment of rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis among Filipino patients.
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis
- Trial name
- NCT01692457
- Testing
- No intervention
- Sponsor
- Janssen Pharmaceutica
Ankylosing Spondylitis
Study Of Celecoxib Or Diclofenac For Efficacy and Safety In Chinese Patients With Ankylosing Spondylitis
This is a local, multicenter, randomized, active comparator, double-blind, parallel group study with extension will be conducted to evaluate the efficacy and safety of celecoxib versus diclofenac SR in the treatment of Chinese…
- Trial name
- NCT00762463
- Testing
- Celecoxib, Diclofenac SR
- Where
- 5 sites in China
- Volunteers
- 240 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Ankylosing Spondylitis, Axial Spondyloarthritis
REduCed Dose of TNFi in Patients With Ankylosing SpondyliTis (RECAST)
Participants maintaining stable disease activity of Ankylosing Spondylitis (AS) with standard-dose tumor necrosis factor inhibitor (TNFi) treatment will randomly split into two groups: maintaining standard-dose TNFi, versus…
- Trial name
- NCT05164198
- Testing
- Adalimumab and its biosimilars, Biological: Etanercept and its biosimilars, Golimumab
- Volunteers
- 448 people
- Sponsor
- Hanyang University Seoul Hospital
Ankylosing Spondylitis
An Extension Study to Demonstrate the Equivalence of Long-Term Efficacy and Safety of CT-P13 in Patients With Ankylosing Spondylitis Who Were Treated With Infliximab (Remicade or CT-P13) in Study CT-P13 1.1
This open-label, single-arm, multicenter, multiple single-dose intravenous (IV) infusion, efficacy, and safety extension study of the Phase 1 Study CT-P13 1.1 is designed to assess the long-term efficacy and safety of multiple…
- Trial name
- NCT01571206
- Testing
- Infliximab
- Where
- South Korea
- Volunteers
- 174 people
- Sponsor
- Celltrion