Clinical trials: Axillary Metastases
Breast Cancer, Lymph Node Metastasis
Axillary LNs Evalution in Breast Cancer by Multimodal Us
The present study is designed to evaluate the role of simultaneous multi-modal sonographic tools-Ultrasound (US), Color Doppler Ultrasound (CDU), and Ultrasound Elastography (UE)-in determining the nature (benign or malignant) of…
- Trial name
- NCT06695052
- Testing
- multi modal Us
- Volunteers
- 30 people
- Sponsor
- Assiut University
Breast Cancer
Rationale and Trial Design of PFB-03 Study: Diagnostic Performance and Clinical Application of 18F-FAPI-PET/CT for Detecting Axillary Lymph Node Metastasis in Breast Cancer Patients After Neoadjuvant Therapy
Axillary lymph node (ALN) status is a crucial prognostic factor in breast cancer. Accurate, non-invasive methods for evaluating axillary lymph node metastasis after neoadjuvant therapy (NAT) are needed to optimize surgical…
- Trial name
- NCT07012707
- Volunteers
- 172 people
- Sponsor
- Peking Union Medical College Hospital
Carcinoma, Lobular
Diagnostic Performance of [18F]FES PET/CT for Axillary LN Metastasis in Invasive Lobular Carcinoma
This study aims to explore the diagnostic validity of [18F]FES PET/CT for the evaluation of axillary lymph node metastasis in patients with invasive lobular breast cancer having clinically suspected or confirmed axillary lymph…
- Trial name
- NCT05960201
- Testing
- [18F]fluoroestradiol (FES)
- Where
- South Korea
- Volunteers
- 23 people
- Sponsor
- Asan Medical Center
Breast Cancer, Axillary Lymph Node Metastasis
A Prospective Multicenter Study of the TuFEst-LN Model for Axillary Lymph Node Status Assessment in Breast Cancer
Through the research of this project, we expect to validate the clinical utility of the TuFEst-LN model in assessing axillary lymph node status in breast cancer patients.
- Trial name
- PRO-TuFEst-LN (NCT07304934)
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Breast Cancer
Sentinel Node Biopsy in Breast Cancner: Omission of Axillary Clearance After Micrometastasis
Sentinel node (SN) biopsy in breast cancer has been demonstrated to be a reliable method, and several follow-up studies have shown that it is safe to refrain from completion axillary clearance (axillary lymph node dissection…
- Trial name
- SENOMIC (NCT02049632)
- Testing
- Omission of axillary clearance
- Where
- 22 sites in Sweden
- Volunteers
- 805 people
- Sponsor
- Karolinska Institutet
Breast Cancer
Evaluation Of Lymph Nodes After Neoadjuvant Chemotherapy
This research protocol is studying the accuracy of the sentinel lymph node biopsy procedure in breast cancer patients who have cancer cells in the lymph nodes in the armpit (axilla) who have received chemotherapy or endocrine…
- Trial name
- NCT02752009
- Testing
- Axillary Lymph Node Sampling Clip
- Sponsor
- Dana-Farber Cancer Institute
Invasive Breast Cancer, Axillary Metastases
Sentinel Lymph Node After Neoadjuvant Chemotherapy in Breast Carcinoma
Sentinel lymph node dissection (SLND) after NAC, aimed to reduce the rate of unnecessary axillary lymphadenectomy, is not a standard of care in case of patient with previously involved node before NAC because of a too high false…
- Trial name
- GANEA3 (NCT03630913)
- Testing
- Tagged axillary metastatic node
- Where
- 18 sites in France
- Volunteers
- 385 people
- Sponsor
- Institut Cancerologie de l'Ouest
Anesthesia, Regional Anesthesia Morbidity
Feasibility of Serratus Plane Block Associated With Sedation in Axillary Dissection
INTRODUCTION: The axillary lymphadenectomy procedure is known to be associated with late postoperative complications, such as chronic pain and changes in shoulder mobility.
- Conditions
- Anesthesia, Regional Anesthesia Morbidity, Axillary Metastases, Nerve Block
- Trial name
- NCT03740815
- Testing
- Serratus plane block, Axillary dissection, Intravenous sedation
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Breast Cancer
Feasibility in Identification of Breast Cancer Candidates for Elimination of Axillary Surgery
Preoperative identification of patients with pathologic complete response or residual disease in axilla can aid in tailoring subsequent axillary surgery including omission of axillary surgery based on tumor biology and response…
- Trial name
- NCT05663021
- Testing
- Ultrasound-guided core needle biopsy in breast
- Where
- China
- Volunteers
- 191 people
- Sponsor
- Fudan University
Breast Neoplasms
Omitting Completion Axillary Treatment in Sentinel Node Positive Breast Cancer Patients Undergoing a Mastectomy
STUDY AIM To decrease the number of breast cancer patients receiving overtreatment of the axilla, in order to positively influence the axillary morbidity rate and quality of life.
- Trial name
- NCT02112682
- Testing
- Completion axillary treatment
- Where
- 31 sites in Netherlands
- Volunteers
- 52 people
- Sponsor
- Maastricht University Medical Center
Breast Cancer Female
Axillary Sentinel or Targeted Lymph Node Biopsy Alone After Neoadjuvant Chemotherapy in Node-positive Breast Cancer
This randomized phase II trial investigates the effectiveness of axillary sentinel or targeted lymph node biopsy alone after neoadjuvant chemotherapy (NAC) in breast cancer patients with initial axillary metastasis.
- Trial name
- NCT05141630
- Testing
- sentinel lymph node biopsy or targeted axillary dissection alone
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fudan University
Breast Cancer
Selective Image Guided Resection of Pathologically Documented Axillary Lymph Node Metastases
The purpose of this research study is to determine how feasible and accurate identifying and removing specific lymph nodes in the axilla (armpit) after neoadjuvant systemic therapy is when patients present with breast cancer that…
- Trial name
- TAD (NCT03281720)
- Testing
- TAD
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Lymphatic Metastasis, Breast Neoplasms
Ultrasound-Guided Core Needle Biopsy to Assess Sensitivity and Specificity of Axillary Lymph Node Metastasis in Breast Cancer
This study plans to find the most suitable lymph node cortex thickness and abnormal lymph node features to define suspicious lymph nodes.
- Trial name
- NCT07573657
- Volunteers
- 200 people
- Sponsor
- The First Hospital of Jilin University
Breast Cancer, Axillary Metastases
ICG vs Blue Patent for TAD in cN1 Breast Carcinoma After Neoadjuvant Chemotherapy
To validate the use of ICG as a tracer during TAD in patients with cN1 breast carcinoma after neoadjuvant chemotherapy.
- Trial name
- NCT06339658
- Testing
- Targeted axillary dissection (TAD) by ICG, Targeted axillary dissection (TAD) by Blue patent
- Where
- Spain
- Volunteers
- 43 people
- Sponsor
- Hospital Universitari de Bellvitge
Melanoma, Skin Cancer
The Aim of This Study is to Demonstrat That Vacuum-assisted Closure Versus Conventional Wound Closure Enables to Diminish Local Complications After Lymph Node Dissection in Patients With Metastatic Skin Tumors
In this study, we compared a negative pressure wound therapy, versus a conventional dressing in order to evaluate the most efficient wound therapy closure after axillary and inguinal lymph nodes dissections in the management of…
- Conditions
- Melanoma, Skin Cancer, Epidermoid Carcinoma, Neuroendocrine Carcinoma
- Trial name
- NCT04583605
- Testing
- PREVENA
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Central Hospital, Nancy, France
Breast Cancer, Axillary Lymph Node Metastasis
Ultrasound Monitoring of Clipped Lymph Nodes to Predict Axillary Response After Chemotherapy in Breast Cancer
This study aims to evaluate whether longitudinal multimodal ultrasound can accurately predict axillary pathological response in breast cancer patients who receive neoadjuvant chemotherapy.
- Conditions
- Breast Cancer, Axillary Lymph Node Metastasis, Neoadjuvant Chemotherapy, Pathological Complete Response
- Trial name
- NCT07596472
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Breast Cancer
Characterizing Breast Cancer With 68Ga-FAPI PET/CT (PFB-01)
Fibroblast activation protein (FAP) is overexpressed in cancer-associated fibroblasts (CAFs), which constitute a major proportion of cells within the tumor microenvironment, especially in breast cancer.
- Trial name
- NCT05574907
- Testing
- 68Ga-FAPI PET/CT scan
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Peking Union Medical College Hospital
Neoplasm, Breast, Neoadjuvant Chemotherapy
To Accurately Assess Lymph Node Response to NACT by Wire Localization of Clip-marked Lymph Nodes
The investigator developed this protocol to accurately assess lymph node response to neoadjuvant chemotherapy in clinical stage N1 (cN1) breast cancer patients.
- Conditions
- Neoplasm, Breast, Neoadjuvant Chemotherapy, Lymph Node Metastases, Response
- Trial name
- NCT03715686
- Testing
- wire localization
- Where
- China
- Volunteers
- 230 people
- Sponsor
- Peking University
Melanoma (Skin)
Interferon Alfa-2b With or Without Radiation Therapy in Treating Patients With Melanoma That Has Metastasized to Lymph Nodes in the Neck, Under the Arm, or in the Groin
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Interferon alfa-2b may interfere with the growth of cancer cells.
- Trial name
- NCT00003444
- Testing
- recombinant interferon alfa, radiation therapy
- Where
- 23 sites in United States
- Volunteers
- 167 people
- Sponsor
- Eastern Cooperative Oncology Group
Breast Cancer
Characterizing Breast Cancer With Al18F-NOTA-FAPI-04 PET/CT (PFB-02)
Fibroblast activation protein (FAP) is overexpressed in cancer-associated fibroblasts (CAFs), which constitute a major proportion of cells within the tumor microenvironment, especially in breast cancer.
- Trial name
- NCT05574920
- Testing
- Al18F-NOTA-FAPI-04 PET/CT scan
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Peking Union Medical College Hospital