Clinical trials: BCC
Skin Cancer
An Appearance-Based Intervention to Reduce Teen Skin Cancer Risk
The purpose of this study is to determine whether a skin cancer prevention website is effective at reduce female teenagers' desire to use indoor tanning and ultimately their use of indoor tanning over an 18 month period.
- Trial name
- iSTART (NCT01508013)
- Testing
- Appearance-Focused Website Intervention, Control Website
- Where
- United States
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- East Tennessee State University
Acute Leukemia, Adenomatous Polyposis
Familial Investigations of Childhood Cancer Predisposition
NOTE: This is a research study and is not meant to be a substitute for clinical genetic testing. Families may never receive results from the study or may receive results many years from the time they enroll.
- Conditions
- Acute Leukemia, Adenomatous Polyposis, Adrenocortical Carcinoma, AML
- Trial name
- SJFAMILY (NCT03050268)
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- St. Jude Children's Research Hospital
Skin Tumors, Melanoma
Skin Cancer Screening Education Study
The overall aim of this population-based screening study is to assess whether the skin cancer screening training of family physicians and dermatologists leads to improved screening outcomes.
- Conditions
- Skin Tumors, Melanoma, Basal Cell Carcinoma, Squamous Cell Carcinoma
- Trial name
- SCSES (NCT02352428)
- Testing
- Skin Cancer Screening Training
- Where
- Canada
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Association of Dermatological Prevention, Germany
Basal Cell Carcinoma, Squamous Cell Carcinoma
Reflectance Confocal Microscopy of Wounds During Moh's Surgery: Feasibility Testing of a Mosaicing Algorithm for Intraoperative Imaging of Cancer Margins
The purpose of this study is to evaluate a new instrument that shines light and takes digital pictures of skin. The goal is to develop a technique that may enable fast and accurate assessment of surgical margins in the excision…
- Trial name
- NCT01872130
- Where
- 4 sites in United States
- Volunteers
- 45 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Head and Neck Cancer
Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants
RATIONALE: Collecting and storing samples of tissue, saliva, and blood from patients with cancer and from healthy participants to study in the laboratory may help the study of cancer in the future.
- Trial name
- NCT00898638
- Testing
- biologic sample preservation procedure, medical chart review
- Where
- 4 sites in United States
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Basal Cell Carcinoma
Checking Wether the m-ALA Cream Could Mark Correctly the Borders of BCC's Tumors
Correlation between Mohs surgery and microscopic fluorescence photometry in determination of histological borders in Basal Cell Carcinoma .
- Trial name
- NCT00449358
- Testing
- apply methyl-ALA cream
- Where
- Israel
- Volunteers
- 32 people
- Sponsor
- Assuta Hospital Systems
Head and Neck Cancer
PET Scans in Patients With Head And Neck Cancer Who Are Undergoing 3-Dimensional Conformal Radiation Therapy And Intensity-Modulated Radiation Therapy
RATIONALE: Imaging procedures, such as PET scans, may determine the extent of cancer and help doctors plan radiation therapy. Radiation therapy uses high-energy x-rays to kill tumor cells.
- Trial name
- TEPORL (NCT00809016)
- Testing
- 3-dimensional conformal radiation therapy, fludeoxyglucose F 18, intensity-modulated radiation therapy
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Oscar Lambret
Malignant Skin Melanoma T0, Basal Cell Carcinoma
DERM US and EU Validation Study
This study aims establish the effectiveness of Image Analysing Algorithm (DERM) to identify melanoma, Squamous Cell Carcinoma (SCC) and Basal Cell Carcinoma (BCC) when used to analyse dermoscopic images of skin lesions within the…
- Conditions
- Malignant Skin Melanoma T0, Basal Cell Carcinoma, Squamous Cell Carcinoma
- Trial name
- NCT05126173
- Testing
- Deep Ensemble for the Recognition of Malignancy (DERM)
- Where
- 16 sites in United States, Italy
- Volunteers
- 1,111 people
- Sponsor
- Skin Analytics Limited
Skin Cancer, Melanoma (Skin)
A Non-Interventional Pilot Study to Explore the Skin Microbes in Skin Cancer
This study seeks to correlate microbial sequencing data from a punch biopsy in patients with skin cancer both melanoma and non-melanoma.
- Conditions
- Skin Cancer, Melanoma (Skin), Squamous Cell Carcinoma, Basal Cell Carcinoma
- Trial name
- NCT04099446
- Testing
- Non-interventional
- Where
- United States
- Sponsor
- ProgenaBiome
Advanced Lymphoma, Advanced Malignant Solid Neoplasm
Testing GDC-0449 (Vismodegib) as Potentially Targeted Treatment in Cancers With Smoothened or Patched 1 Mutant Tumors (MATCH - Subprotocol T)
This phase II MATCH treatment trial tests how well GDC-0449 (vismodegib) works for treating patients with solid tumors, lymphoma, or multiple myeloma that may have spread from where it first started to nearby tissue, lymph nodes…
- Conditions
- Advanced Lymphoma, Advanced Malignant Solid Neoplasm, Hematopoietic and Lymphatic System Neoplasm, Refractory Lymphoma
- Trial name
- NCT06357988
- Testing
- Biopsy Procedure, Biospecimen Collection, Echocardiography Test
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- National Cancer Institute (NCI)
BCC - Basal Cell Carcinoma, BCC
The Diagnostic Accuracy of Advanced Imaging in Identifying Suspected Skin Cancer (Basal Cell Carcinoma) Around the Eyes
The purpose is to investigate the diagnostic value (sensitivity and specificity) of dermal-Optical Coherence Tomography (D-OCT, VivoSight Dx), in patients with clinically suspected BCC lesions inside the periocular region and…
- Conditions
- BCC - Basal Cell Carcinoma, BCC, Skin Diseases, Eyelid Tumor
- Trial name
- dOCT-pBCC (NCT06279143)
- Where
- Denmark
- Volunteers
- 210 people
- Sponsor
- Vejle Hospital
Basal Cell Carcinoma
Short Term Effects of Photodynamic Therapy in Basal Cell Carcinoma
The purpose of this study is to evaluate the efficacy of photodynamic therapy in treatment of Basal cell carcinoma (BCC) and factors that affect response rate.
- Trial name
- NCT01015898
- Testing
- photodynamic therapy
- Volunteers
- 28 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Ocular Sebaceous Carcinoma, Ocular Basal Cell Carcinoma
Sentinel Lymph Node Biopsy in Ocular Surface and Adnexal Cancers
The study involves enrollment of patients with sebaceous carcinoma, Merkel's carcinoma, Porocarcinoma, Melanoma, and squamous cell Ca of the ocular surface and adnexa both primary and relapsed after surgical and/or…
- Conditions
- Ocular Sebaceous Carcinoma, Ocular Basal Cell Carcinoma, Ocular Surface Squamous Neoplasia, Merkel Cell Carcinoma, Unspecified
- Trial name
- BLS (NCT05797415)
- Testing
- Sentinel Lymph Node Biopsy
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Basal Cell Carcinoma, Gorlin Syndrome
Efficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)
This was a phase II, double-blind, randomized, proof-of-concept, dose-ranging trial evaluating the efficacy, safety and pharmacokinetics of oral LDE225 in treatment of adult patients with NBCCS.
- Conditions
- Basal Cell Carcinoma, Gorlin Syndrome, Nevoid Basal Cell Carcinoma Syndrome
- Trial name
- NCT01350115
- Testing
- LDE225
- Where
- 6 sites in Austria, Belgium and 2 more
- Volunteers
- 10 people
- Sponsor
- Novartis Pharmaceuticals
Malignant Melanoma, Merkel Cell Carcinoma
Optical Biopsy of Human Skin in Conjunction With Laser Treatment
This study is to compare the ability of optical biopsy. Research can use light enters the skin, collected, analyzed by the computer, and a picture created for the pathologist to conventional histologic examination compare with…
- Conditions
- Malignant Melanoma, Merkel Cell Carcinoma, Basal Cell Carcinoma, Squamous Cell Carcinoma
- Trial name
- NCT00540566
- Testing
- Optical Biopsy imaging
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Melanoma, Cutaneous Squamous Cell Carcinoma
Personalised Immunotherapy Platform
This is a non-interventional study to prospectively test a suite of predictive biomarker models of immunotherapy resistance in patients with melanoma, non-melanoma skin cancers and other solid tumours.
- Conditions
- Melanoma, Cutaneous Squamous Cell Carcinoma, Basal Cell Carcinoma, Merkel Cell Carcinoma
- Trial name
- PIP-PREDICT (NCT06536257)
- Testing
- Predictive model
- Where
- 3 sites in Australia
- Volunteers
- 1,000 people
- Sponsor
- Melanoma Institute Australia
Nodular Basal Cell Carcinoma, Superficial Basal Cell Carcinoma
Randomized Pilot Study of Treatment for BCC Using the Multiplex 595/1064 nm Laser
Laser therapy for basal cell carcinoma may be a superior option for patients who do not wish to or cannot tolerate other treatment modalities such as topical chemotherapeutics or surgery.
- Trial name
- BCC (NCT02270645)
- Testing
- 595/1064 multiplex laser
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Miami
Basal Cell Carcinoma
Evaluation of Efficacy of Photodynamic Therapy in Basal Cell Carcinoma With 6 Months Follow-up
The purpose of this study is to evaluate the efficacy of photodynamic therapy (PDT)in treatment of Basal cell carcinoma (BCC) and recurrence rate after 6 months.
- Trial name
- NCT00988455
- Testing
- photodynamic therapy
- Volunteers
- 28 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Carcinoma, Basal Cell, Carcinoma, Squamous Cell
Optical Imaging for Preoperative Delineation of Nonmelanoma Skin Cancers
The purpose of the study is to evaluate the ability and efficacy of using a polarization-enhanced reflectance and fluorescence imaging device, PERFIS, (see the Device Brochure) for demarcation of nonmelanoma skin cancer margins…
- Trial name
- PERFIS (NCT02666833)
- Testing
- Polarization Enhanced Reflectance and Fluorescence System
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Carcinoma, Basal Cell
To Assess The Efficacy And Safety Of Vismodegib And Radiotherapy In Advanced Basal Cell Carcinoma
This is a Fleming-A' Hern, single arm, multicenter, no-profit, phase II study of radiotherapy and Vismodegib in adult patients with high risk or locally advanced basal cell carcinoma not amenable to radical surgery cell carcinoma…
- Trial name
- virgilio (NCT02956889)
- Testing
- Vismodegib, Radiotherapy
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- Istituto Clinico Humanitas