Clinical trials: BCC
Superficial Basal Cell Carcinoma
To Determine the Maximum Tolerated Dose Level (MTD) of PEP005 Topical Gel in Patients With sBCC
The purpose of this study is to determine maximum tolerated dose level (MTD) of PEP005 Topical Gel for the treatment of superficial basal cell carcinoma on the trunk
- Trial name
- NCT00432185
- Testing
- PEP005
- Where
- 9 sites in United States
- Volunteers
- 117 people
- Sponsor
- Peplin
Colorectal Cancer, Head and Neck Cancer
NGR-TNF in Treating Patients With Advanced Solid Tumors
RATIONALE: Targeted therapy with tumor necrosis factor combined with a fusion protein may stop the growth of solid tumors by stopping blood flow to the tumor.
- Conditions
- Colorectal Cancer, Head and Neck Cancer, Kidney Cancer, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00098943
- Testing
- CNGRC peptide-TNF alpha conjugate
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 70 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Skin Cancer, Melanoma (Skin Cancer)
Liquid Biomarker Study in Melanoma and Non-Melanoma Skin Cancers
The goal of this observational study is to study blood samples and compare them to other biospecimens and clinical outcomes in participants who have melanoma or non-melanoma skin cancers.
- Conditions
- Skin Cancer, Melanoma (Skin Cancer), Basal Cell Carcinoma of Skin, Basal Cell Carcinoma of Skin, Site Unspecified
- Trial name
- NCT06608511
- Testing
- Blood draw for the laboratory assessment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Basal Cell Carcinoma
An Observational Study of Treatment Patterns and Effectiveness and Safety Outcomes in Advanced Basal Cell Carcinoma and Basal Cell Carcinoma Nevus Syndrome Patients(RegiSONIC)
This multi-center, prospective, observational cohort study will evaluate the effectiveness, safety and utilization of treatments in patients with advanced basal cell carcinoma and basal cell carcinoma nevus syndrome.
- Trial name
- NCT01604252
- Where
- 81 sites in United States, Puerto Rico
- Volunteers
- 503 people
- Sponsor
- Genentech, Inc.
Basal Cell Carcinoma
Vismodegib on Locally Advanced Basal Cell Carcinoma Under Real World Conditions
The aim of this non-interventional study is to provide further data on the utilization, effectiveness, safety and clinical benefit including duration of response of Vismodegib for treatment of locally advanced basal cell…
- Trial name
- JONAS (NCT02781389)
- Where
- Germany
- Volunteers
- 53 people
- Sponsor
- University Hospital, Essen
Basal Cell Carcinoma
Pilot LDE225 in Locally Advanced or Metastatic BCC + Previously Tx Non-LDE225 Smoothened Inhibitors
This is a prospective single-center, open label, pilot study to investigate the safety and efficacy of LDE225 in patients with locally advanced or metastatic basal cell carcinoma.
- Trial name
- NCT01529450
- Testing
- LDE225
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Anne Chang
Basal Cell Carcinoma
To Assess the Safety and Efficacy of SP-002 with Vismodegib for the Treatment of Locally Advanced Basal Cell Carcinoma
The goal of this clinical trial is to evaluate the efficacy of using SP-002 in participants with locally advanced Basal cell carcinoma.
- Trial name
- NCT06344052
- Testing
- SP-002, Vismodegib
- Where
- 10 sites in United States
- Volunteers
- 80 people
- Sponsor
- Stamford Pharmaceuticals, Inc.
Basal Cell Carcinoma
Study to Determine the Safety of Two Applications of PEP005 Topical Gel to Superficial Basal Cell Carcinoma
The purpose of this study is to determine whether topical application of PEP005 is safe for the treatment of superficial basal cell carcinoma.
- Trial name
- NCT00108134
- Testing
- PEP005
- Where
- 9 sites in Australia
- Volunteers
- 60 people
- Sponsor
- Peplin
Basal Cell Carcinoma
An Analysis of Treatment Patterns and Outcomes for Basal Cell Carcinoma (BCC) Cancer Participants
This multi-center, observational study involves reviewing the medical records of approximately 100 adult participants diagnosed with advanced BCC from 01 January 2005 until 31 December 2010.
- Trial name
- NCT02100111
- Where
- 42 sites in France, Germany and 2 more
- Volunteers
- 134 people
- Sponsor
- Hoffmann-La Roche
Basal Cell Carcinoma (BCC), Skin Cancer
Pilot Biomarker Trial to Evaluate the Efficacy of Itraconazole in Patients w/ Basal Cell Carcinomas
Basal cell carcinomas (BCCs) are the most common human cancer in the US and affect over 1 million people. There is no effective drug to prevent basal cell carcinomas of the skin.
- Trial name
- NCT01108094
- Testing
- Itraconazole
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Stanford University
Type2 Diabetes, Diabetes Mellitus, Type 2
Effects of Basic Carbohydrate Counting Versus Standard Outpatient Nutritional Education in Type 2 Diabetes
The aim of the study is to examine the health benefits of adding a concept in basic carbohydrate counting (BCC) to the routine outpatient nutritional education for adult patients with type 2 diabetes.
- Conditions
- Type2 Diabetes, Diabetes Mellitus, Type 2, Glucose Metabolism Disorders
- Trial name
- NCT03623139
- Testing
- Standard nutritional education, Basic carbohydrate counting
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Steno Diabetes Center Copenhagen
Skin Cancers - Basal Cell Carcinoma, Skin Cancers - Squamous Cell Carcinoma
An Observational Study Using The LumAssure Device In Participants Undergoing Assessment Of Skin Conditions.
This is an observational study in adult males and females utilising skin condition measurements using the LumAssure Raman device.
- Conditions
- Skin Cancers - Basal Cell Carcinoma, Skin Cancers - Squamous Cell Carcinoma, Melanoma of Skin, Inflammatory Dermatoses
- Trial name
- NCT06661577
- Where
- 2 sites in New Zealand
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Cancer
Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer
RATIONALE: Drugs used in chemotherapy, such as cyclophosphamide, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00499733
- Testing
- cyclophosphamide, Cryoablation
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Basal Cell Carcinoma
A Study of Vismodegib (GDC-0449) in Patients With Locally Advanced or Metastatic Basal Cell Carcinoma
This is an open-label, non-comparative, multicenter, expanded access study of Vismodegib (GDC-0449) in patients with locally advanced basal cell carcinoma (BCC) or metastatic BCC (mBCC) who are otherwise without satisfactory…
- Trial name
- NCT01160250
- Testing
- vismodegib (GDC-0449)
- Where
- 11 sites in United States
- Sponsor
- Genentech, Inc.
Basal Cell Carcinoma
Differential Mobility Spectrometry (DMS) Based Skin Tumor Analysis
The trial is a single-center, non-randomized feasibility study aiming to evaluate the feasibility of ex-vivo tissue analysis using differential mobility spectrometry (DMS) of tissue smoke generated by the use of an…
- Trial name
- NCT05247710
- Testing
- Punch biopsy
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- Tampere University Hospital
Non-melanomatous Skin Cancer, Precancerous/Nonmalignant Condition
Eflornithine With or Without Triamcinolone in Preventing Nonmelanoma Skin Cancer in Patients With Actinic Keratosis
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. Eflornithine with or without triamcinolone may be effective in preventing nonmelanoma skin cancer.
- Trial name
- NCT00021294
- Testing
- eflornithine, triamcinolone
- Where
- United States
- Sponsor
- University of Arizona
Cutaneous Squamous Cell Carcinoma, Squamous Cell Carcinoma
A Window of Opportunity Trial of Intratumoral Injection of Copaxone® in Patients With Percutaneously Accessible Tumors
The investigator believes that injecting Copaxone into tumors will help participants immune system fight cancer. This has been studied in mice and has shown encouraging results.
- Conditions
- Cutaneous Squamous Cell Carcinoma, Squamous Cell Carcinoma, Basal Cell Carcinoma
- Trial name
- NCT03982212
- Testing
- Copaxone
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Kansas Medical Center
Basal Cell Carcinoma
A Study to Evaluate Effectiveness of Imiquimod 5% Cream in Superficial Basal Cell Carcinoma
The purpose of this study is to evaluate the long-term sustained clearance rate of superficial basal cell carcinoma during a 5 year period following treatment with imiquimod
- Trial name
- NCT00189241
- Testing
- imiquimod
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- MEDA Pharma GmbH & Co. KG
Basal Cell Cancer
AI in Histipathological Diagnosis of Bcc
The goal of this study is to evaluate the diagnostic performance of an Artificial Intelligence (AI) algorithm in the histopathological diagnosis of bcc compared to certified dermatopathologists
- Trial name
- AI\bcc (NCT07786376)
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Skin Cancer, Mucosal Neoplasm of Oral Cavity
Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia
A unique approach for cancer treatment employing intratumoral diffusing alpha radiation emitter device for superficial cutaneous, mucosal or soft tissue neoplasia
- Conditions
- Skin Cancer, Mucosal Neoplasm of Oral Cavity, Soft Tissue Neoplasm
- Trial name
- NCT04534127
- Testing
- Radiation: Diffusing Alpha Radiation Emitters Therapy (DaRT)
- Where
- Israel
- Volunteers
- 56 people
- Sponsor
- Alpha Tau Medical LTD.