Clinical trials: BCC
Basal Cell Carcinomas
Transcriptomic Analysis and Optical Coherence Tomography Combined for Patients With Basal Cell Carcinoma
The goal of this observational study is to learn if tape strip for transcriptomic (RNA) analysis and optical coherence tomography (OCT) combined can optimize noninvasive management of basal cell carcinoma (BCC) patients.
- Trial name
- RNA-OCT-BCC (NCT06813833)
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Bispebjerg Hospital
Superficial Basal Cell Carcinoma, Squamous Cell Carcinoma in Situ
5-Fluorouracil and Calcipotriene for Treatment of Low Grade Skin Cancer
The investigators will compare the application of two different creams for the treatment of low-risk skin cancers-superficial basal cell carcinoma (sBCC) and squamous cell carcinoma in situ (SCCis).
- Trial name
- NCT05381597
- Testing
- Combination cream of 5-fluorouracil and calcipotriene, 5-fluorouracil cream
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Boston University
Advanced Solid Tumors, Recurrent or Refractory Medulloblastoma
A Dose Finding and Safety Study of Oral LEQ506 in Patients With Advanced Solid Tumors
This first-in-human dose-escalation study is to characterize the safety, tolerability, pharmacokinetics and pharmacodynamics of LEQ506 given orally on a daily dosing schedule in patients with advanced solid tumors.
- Conditions
- Advanced Solid Tumors, Recurrent or Refractory Medulloblastoma, Locally Advanced or Metastatic Basal Cell Carcinoma
- Trial name
- NCT01106508
- Testing
- LEQ506
- Where
- 5 sites in United States, Netherlands and 2 more
- Volunteers
- 57 people
- Sponsor
- Novartis Pharmaceuticals
Non-melanoma Skin Cancer, Basal Cell Carcinoma
Imvamune Vaccine for the Treatment of Non-melanoma Skin Cancer
This study examines the safety and efficacy of using the Imvamune smallpox vaccine in the treatment of non-melanoma skin cancers (basal cell carcinoma and squamous cell carcinoma).
- Conditions
- Non-melanoma Skin Cancer, Basal Cell Carcinoma, Squamous Cell Carcinoma
- Trial name
- MUSIC-01 (NCT04410874)
- Testing
- Imvamune
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Ivan Litvinov
Actinic Keratosis, Basal Cell Carcinoma of the Skin
T4N5 Liposomal Lotion in Preventing The Recurrence of Nonmelanoma Skin Cancer in Patients Who Have Undergone a Kidney Transplant
This randomized phase II trial is studying how well T4N5 liposomal lotion works in preventing the recurrence of nonmelanoma skin cancer in patients who have undergone a kidney transplant.
- Conditions
- Actinic Keratosis, Basal Cell Carcinoma of the Skin, Recurrent Skin Cancer, Squamous Cell Carcinoma of the Skin
- Trial name
- NCT00089180
- Testing
- liposomal T4N5 lotion, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Cancer Institute (NCI)
Basal Cell Carcinoma
Observational Study of Correlation Between Recurrent Basal Cell Carcinoma and Localisation
.During one year all the resected basal cell carcinomas (BCC) analyzed in Montpellier University Hospital Anatomopathology unit were included in this study. Localisation and histological characteristics were collected.
- Trial name
- NCT04795297
- Where
- France
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Basal Cell Carcinoma
Clinical Trial to Evaluate BO-112 in Patients With Basal Cell Carcinoma (BCC)
This is a multicenter, phase 2b, open-label, non-randomized, clinical trial to evaluate safety, tolerability, pharmacodynamics and preliminary efficacy of intra-lesional BO-112 in patients with resectable primary low and high…
- Trial name
- SPOTLIGHT204 (NCT06422936)
- Testing
- BO-112
- Where
- 10 sites in Israel, Spain
- Volunteers
- 50 people
- Sponsor
- Highlight Therapeutics
Skin Cancer
Confocal Microscopy of Benign and Malignant Skin Tumors
The investigators speculate that this tool may be used as an alternative and convenient non-invasive diagnostic of skin cancer.
- Trial name
- NCT01010321
- Testing
- confocal microscopy
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Advanced Solid Tumors, MSI-H/dMMR Tumors
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors
The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics, and pharmacodynamics of INCB099318 in select solid tumors.
- Conditions
- Advanced Solid Tumors, MSI-H/dMMR Tumors, Cutaneous Squamous Cell Carcinoma, Urothelial Carcinoma, HCC
- Trial name
- NCT04272034
- Testing
- INCB099318
- Where
- 24 sites in United States, Belgium and 5 more
- Volunteers
- 105 people
- Sponsor
- Incyte Corporation
Non-melanomatous Skin Cancer
Eflornithine to Prevent Skin Cancer in Patients With Previously Treated Early Stage Skin Cancer
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of eflornithine may be an effective way to prevent the recurrence of or further development of skin…
- Trial name
- NCT00005884
- Testing
- eflornithine
- Sponsor
- University of Wisconsin, Madison
Basal Cell Carcinoma
Laser Treatment of Basal Cell Carcinoma
Laser treatment of Basal cell carcinoma
- Trial name
- NCT04936932
- Testing
- 1064 nm long-pulse Nd:YAG laser
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Sciton
Advance Directives, Oncology
ACCEPTABILITY AND WRITING FREQUENCY OF ADVANCED DIRECTIVES IN ONCO-DERMATOLOGY PATIENTS
The law about advance directives is evolving but, in France, few people write it. Te main endpoint of this research is to estimate the proportion of patients who have written their advance directives or considering doing so in…
- Conditions
- Advance Directives, Oncology, Skin Cancer, Melanoma
- Trial name
- PADAONCODERM (NCT03822988)
- Testing
- no intervention, only complete a survey
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Central Hospital, Nancy, France
Basal Cell Carcinoma, Chondrosarcoma
IPI-926 Extension Protocol for Continuation of Treatment With IPI-926
A treatment protocol that enables patients to have continued access to IPI-926.
- Trial name
- NCT01609179
- Testing
- IPI-926
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Infinity Pharmaceuticals, Inc.
Basal Cell Carcinoma of the Skin
Evaluation of the Efficiency and Economic Impact of LC-OCT (Line-field Confocal Optical Coherence Tomography) for the Diagnosis and Management of Basal Cell Carcinomas
This is a comparative, randomized, prospective, multicenter clinical investigation aimed at evaluating the efficiency and economic impact of LC-OCT (Line-field Confocal Optical Coherence Tomography) for the diagnosis and…
- Trial name
- ECOBASO (NCT06271603)
- Testing
- diagnosis based on deepLive™ LC-OCT device, diagnosis based on skin biopsy
- Where
- France
- Volunteers
- 704 people
- Sponsor
- Damae Medical
Superficial Basal Cell Carcinoma
Study to Evaluate the Safety and Efficacy of BF-200 ALA (Ameluz®) and BF-RhodoLED® in the Treatment of Superficial Basal Cell Carcinoma (sBCC) With Photodynamic Therapy (PDT).
The aim of this study is to test the safety and efficacy of photodynamic therapy (PDT) with the medication Ameluz® performed with the PDT-lamp BF-RhodoLED® in comparison to the respective placebo treatment for superficial basal…
- Trial name
- NCT03573401
- Testing
- Photodynamic therapy (PDT) (ALA-PDT, Ameluz®-PDT)
- Where
- 18 sites in United States
- Volunteers
- 187 people
- Sponsor
- Biofrontera Inc.
Nodular Basal Cell Carcinoma
Surgery Versus Combined Treatment With Curettage and Imiquimod for Nodular Basal Cell Carcinoma
Basal cell carcinoma (BCC) is a slow-growing, locally invasive malignant epidermal skin tumour. It is the most common malignant disease in Caucasians, representing approximately 80% of all cases of skin cancer and is therefore an…
- Trial name
- SCIN (NCT02242929)
- Testing
- Imiquimod 5% cream with prior curettage, Standard surgical excision
- Where
- Netherlands
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Squamous Cell Carcinoma, Basal Cell Carcinoma
Molecular Characterization of Cutaneous Tumors
The objective is to find genes which are responsible for the appearance of skin tumors (sCC, BCC) and it will be the basis for prediction of the disease and response to the treatment
- Trial name
- NCT03092830
- Testing
- Molecular testing of DNA/RNA from skin tumors, SCC/BCC
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Rabin Medical Center
Carcinoma, Basal Cell
A Randomised Study Comparing Tissue Conservation in Conventional Versus Mohs' Surgery of Basal Cell Carcinoma
We have compared to types of surgery to assess which one leaves the smaller surgical defect.
- Trial name
- NCT00571363
- Testing
- standard surgery, Mohs micrographic surgery
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- NHS Tayside
Head and Neck Cancer
Customized Headrest or Standard Headrest in Holding Patients Still While Undergoing Radiation Therapy for Head and Neck Cancer
RATIONALE: Using a customized headrest to hold patients in one position may help doctors plan treatment for patients with head and neck cancer.
- Trial name
- NCT00973947
- Testing
- questionnaire administration, 3-dimensional conformal radiation therapy, radiation therapy treatment planning/simulation
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- Cancer Trials Ireland
Non-melanomatous Skin Cancer, Precancerous Condition
Photodynamic Therapy in Treating Patients With Skin Cancer
RATIONALE: Photodynamic therapy uses light and drugs that make cancer cells more sensitive to light to kill tumor cells. Photodynamic therapy using aminolevulinic acid may be effective in treating patients with skin cancer.
- Trial name
- NCT00002975
- Testing
- aminolevulinic acid
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Roswell Park Cancer Institute