Clinical trials: BCC - Basal Cell Carcinoma
Non-melanoma Skin Cancer
Prognostic Value of RXR-α in Cutaneous Squamous and Basal Cell Carcinoma
Vitamin D has a crucial role in cancer control and prevention.vitamin D receptor (VDR) and its heterodimer Retinoid X receptor (RXR) are equally important in the cell.
- Trial name
- NCT05550766
- Volunteers
- 50 people
- Sponsor
- Sohag University
Nodular Basal Cell Carcinoma of Skin
Photodynamic Therapy Associated With Sonodynamic Therapy for the Treatment of Nodular Basal Cell Carcinoma
Evaluation of a therapeutic protocol based on the combination of photodynamic therapy and sonodynamic therapy, referred to as sonophotodynamic therapy.
- Trial name
- NCT07381972
- Testing
- Control Arm (Conventional Therapy), Experimental arm
- Where
- Brazil
- Volunteers
- 142 people
- Sponsor
- University of Sao Paulo
Eyelid Tumor
Mohs Surgery Combind With Cryotherapy for Eyelid Malignant Tumors.
This study aim to investigate whether the prognosis of eyelid malignant tumor is better treated with Mohs surgery combind with cryotherapy than Mohs surgery only.
- Trial name
- NCT05072327
- Testing
- Mohs surgery, cryotherapy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Sun Yat-sen University
Bladder Cancer, Breast Cancer
Combination Chemotherapy Plus Filgrastim in Treating Patients With Advanced Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Colony-stimulating factors such as filgrastim may increase the number of immune cells found in bone marrow or…
- Conditions
- Bladder Cancer, Breast Cancer, Carcinoma of Unknown Primary, Esophageal Cancer
- Trial name
- NCT00014456
- Testing
- filgrastim, docetaxel, gemcitabine hydrochloride
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Identify Volatile Biomarkers Specific to Malignant Melanoma, Basal Cell Carcinoma and Squamous Cell Carcinoma, Verify That the Volatile Biomarkers Identified Derive From Metabolic Changes in Body Odour and Not Just From Changes in the Surface of Cancerous Lesions
Identification of Olfactory Biomarkers of Skin Cancer From Skin Odor Samples: a Pilot Study
The aim of this research is to determine which volatile organic compounds (odors) are associated with different skin cancers. To this end, odor samples will be taken from various parts of the body, from patients with skin cancers…
- Trial name
- SCENT-SKIN-001 (NCT06493786)
- Testing
- Collection of body odor samples
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Association pour la Recherche Clinique et Immunologique
Carcinoma, Basal Cell
Aldara for the Treatment of Large and/or Multiple sBCC
BCC is the most common form of skin cancer. Current treatment is often surgery but this can be limited by the number of lesions, their location the age of the patient or the potential cosmetic outcome.
- Trial name
- NCT00189280
- Testing
- Imiquimod
- Where
- France
- Volunteers
- 111 people
- Sponsor
- MEDA Pharma GmbH & Co. KG
Melanoma (Skin), Nevus
Clinical vAlidation of a MobilE appLication ("ProRodinki") in the Assessment of the maLignant skIn neoplAsms
A Multicenter, Prospective, Low-interventional Clinical Study Evaluating on mobile application validation ("ProRodinki") in assessing the risk of skin malignant neoplasms
- Conditions
- Melanoma (Skin), Nevus, Nevus, Spitz, Nevus Halo
- Trial name
- CAMELLIA (NCT05402046)
- Testing
- Mobile phone application "ProRodinki"
- Where
- 2 sites in Russia
- Volunteers
- 605 people
- Sponsor
- MelanomaPRO, Russia
Carcinoma, Basal Cell
Post-occlusive Reactive Hyperemia and Basal-cell Carcinoma
The investigators aim to test the hypothesis and to proof thank to laser speckle contrast imaging that post-occlusive reactive hyperemia (PORH) can be induced through a tumor, in this case, through a basal cell carcinoma, which…
- Trial name
- HPOB (NCT01455363)
- Testing
- BCC surgery, Tourniquet ischemia, Laser speckle imaging
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Institut Curie
Skin Cancer, Melanoma (Skin Cancer)
Liquid Biomarker Study in Melanoma and Non-Melanoma Skin Cancers
The goal of this observational study is to study blood samples and compare them to other biospecimens and clinical outcomes in participants who have melanoma or non-melanoma skin cancers.
- Conditions
- Skin Cancer, Melanoma (Skin Cancer), Basal Cell Carcinoma of Skin, Basal Cell Carcinoma of Skin, Site Unspecified
- Trial name
- NCT06608511
- Testing
- Blood draw for the laboratory assessment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Esophageal Cancer, Extrahepatic Bile Duct Cancer
Epirubicin, Carboplatin, and Capecitabine in Treating Patients With Unresectable Locally Advanced, Metastatic, or Recurrent Solid Tumor
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Conditions
- Esophageal Cancer, Extrahepatic Bile Duct Cancer, Gastric Cancer, Head and Neck Cancer
- Trial name
- NCT00021047
- Testing
- capecitabine, carboplatin, epirubicin hydrochloride
- Where
- 3 sites in United States
- Sponsor
- National Institutes of Health Clinical Center (CC)
Skin Cancer, Mucosal Neoplasm of Oral Cavity
Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia.
A unique approach for cancer treatment employing intratumoral diffusing alpha radiation emitter device for superficial cutaneous, mucosal or soft tissue neoplasia
- Conditions
- Skin Cancer, Mucosal Neoplasm of Oral Cavity, Soft Tissue Neoplasm
- Trial name
- NCT03889899
- Testing
- Radiation: Diffusing Alpha Radiation Emitters Therapy (DaRT)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Alpha Tau Medical LTD.
Basal Cell Carcinoma, Squamous Cell Carcinoma
Study Assessing the Safety and Performance of Smart Matrix®
Smart Matrix is a sterile, single layer dermal replacement scaffold. The scaffold consists of a porous matrix of cross-linked human fibrin plus alginate that has been designed and optimised to facilitate wound closure and healing…
- Trial name
- NCT03742726
- Testing
- Smart Matrix scaffold
- Where
- 4 sites in United Kingdom
- Volunteers
- 32 people
- Sponsor
- Smart Matrix Limited
Basal Cell Carcinoma
Laser Treatment of Basal Cell Carcinoma
Laser treatment of Basal cell carcinoma
- Trial name
- NCT04936932
- Testing
- 1064 nm long-pulse Nd:YAG laser
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Sciton
Breast Cancer, Colorectal Cancer
Family Quality of Life Among Families With a Member Who is a Cancer Patient
RATIONALE: Developing a questionnaire that can be used to assess the quality of life among people who have a family member with cancer may help the study of cancer in the future.
- Conditions
- Breast Cancer, Colorectal Cancer, Head and Neck Cancer, Lung Cancer
- Trial name
- NCT00544336
- Testing
- questionnaire administration, survey administration, quality-of-life assessment
- Where
- 3 sites in United States
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Basal Cell Carcinoma, Squamous Cell Carcinoma
Set-back Suture Versus Traditional Vertical Mattress Suture
The investigators hope to compare two different methods of closing skin wounds using sutures. One of these methods (the set-back technique) was recently described in 2010 and has been reported to be technically easier and reduces…
- Conditions
- Basal Cell Carcinoma, Squamous Cell Carcinoma, Melanoma
- Trial name
- NCT01773447
- Testing
- Set-back suture, Vertical mattress suture
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of California, Davis
Carcinoma
Study Evaluating the Efficacy and Safety of 0.05% Ingenol Mebutate (Picato® 500) in the Treatment of Basal Cell Carcinoma
Basal cell carcinomas (BCCs) are the most common form of cancer. The treatment of BCC can be surgical or topical for the low-risk subtypes. Topical treatments used for BCC are imiquimod and photodynamic therapy (PDT).
- Trial name
- PICABAS (NCT03546166)
- Testing
- Picato 0.05% Topical Gel
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Basal Cell Carcinoma, Cutaneous Squamous Cell Carcinoma
FLASH Radiotherapy for Skin Cancer
This is a single center randomized selected Phase II study of FLASH radiotherapy (RT) versus standard of care (SOC) radiotherapy in patients with localized Cutaneous Squamous Cell Carcinoma (cSCC) or Basal Cell Carcinoma (BCC).
- Trial name
- LANCE (NCT05724875)
- Testing
- FLASH RT, Conventional RT
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Carcinoma, Basal Cell
Mohs Versus Traditional Surgery - Basal-Cell Carcinomas (BCC)
Mohs' micrographic surgery (MMS) is a treatment of choice for high recurrence risk basal-cell carcinomas (BCC). Realized under local anaesthesia, it induces very low recurrence rates and spares unnecessary excision of intact…
- Trial name
- BACHIMO (NCT00699829)
- Where
- France
- Volunteers
- 450 people
- Sponsor
- Hospital Ambroise Paré Paris
Head and Neck Cancer, Oral Complications
Cevimeline in Treating Patients With Dry Mouth Caused by Radiation Therapy for Head and Neck Cancer
RATIONALE: Cevimeline may be effective in treating dry mouth that is caused by radiation therapy for head and neck cancer. It is not yet known if cevimeline is more effective than no therapy in treating dry mouth caused by…
- Conditions
- Head and Neck Cancer, Oral Complications, Radiation Toxicity
- Trial name
- NCT00017511
- Testing
- cevimeline hydrochloride
- Where
- 71 sites in United States
- Sponsor
- Daiichi Sankyo
Cancer
MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma
RATIONALE: MS-275 may stop the growth of cancer cells by blocking the enzymes necessary for their growth. PURPOSE: This phase I trial is studying the side effects and best dose of MS-275 in treating patients with advanced solid…
- Trial name
- NCT00020579
- Testing
- entinostat
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- National Institutes of Health Clinical Center (CC)