Clinical trials: BCC - Basal Cell Carcinoma
Advanced Solid Tumors, Genital Neoplasm, Female
A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
This is an open label, multicenter, phase 1/2 study to assess the safety/tolerability and preliminary clinical activity of STAR0602 as a single agent and in combination with chemotherapy administered intravenously in participants…
- Conditions
- Advanced Solid Tumors, Genital Neoplasm, Female, Urogenital Neoplasms, Lung Neoplasm
- Trial name
- START-001 (NCT05592626)
- Testing
- STAR0602, Irinotecan (Camptosar), Docetaxel (Taxotere)
- Where
- 19 sites in United States, Canada and 2 more
- Volunteers
- 366 people
- Sponsor
- Marengo Therapeutics, Inc.
Carcinoma, Basal Cell
Topical Laser-assisted Combination Chemotherapy for Basal Cell Carcinoma- a Clinical Study
A prospective clinical, uncontrolled, open-label, explorative phase IIa trial on patients with histologically- confirmed superficial and nodular basal cell carcinoma (BCC) .
- Trial name
- NCT03541252
- Testing
- AFL-assisted cisplatin+5-FU
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Merete Haedersdal
Superficial Basal Cell Carcinoma
Open-label Study to Evaluate Clearance of Superficial Basal Cell Carcinoma After Use of Imiquimod 5% Cream
An open-label study to evaluate the safety and the ability of Imiquimod 5% cream, applied topically, to clear superficial basal cell carcinoma and to keep it clear for 5 years of follow-up.
- Trial name
- NCT00189306
- Testing
- Imiquimod 5% cream
- Where
- 18 sites in Australia, New Zealand
- Volunteers
- 169 people
- Sponsor
- Graceway Pharmaceuticals, LLC
Basal Cell Carcinoma
Observational Study of Correlation Between Recurrent Basal Cell Carcinoma and Localisation
.During one year all the resected basal cell carcinomas (BCC) analyzed in Montpellier University Hospital Anatomopathology unit were included in this study. Localisation and histological characteristics were collected.
- Trial name
- NCT04795297
- Where
- France
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Skin Cancer
A Community-based Educational Initiative to Raise Awareness of Melanoma and Other Skin Cancers.
This is a pilot study of a community- based melanoma educational intervention in Bensonhurst, Brooklyn conducted in-person by a community-health worker employed by the Perlmutter Cancer Center.
- Trial name
- NCT07177638
- Testing
- Education Sessions to Improve Melanoma Knowledge and Awareness
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Non-melanomatous Skin Cancer
Acitretin in Preventing Skin Cancers in Patients With Previously Treated Skin Cancers Who Have Undergone Organ Transplantation
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of acitretin may be an effective way to prevent the recurrence or further development of skin…
- Trial name
- NCT00003611
- Testing
- acitretin
- Where
- 11 sites in United States
- Volunteers
- 129 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Advanced Solid Tumor Cancers, Medulloblastoma
Dose Finding and Safety of Oral LDE225 in Patients With Advanced Solid Tumors
This first-in-human dose-escalation study is to characterize the safety, tolerability, pharmacokinetics and pharmacodynamics of LDE225 given orally on a daily dosing schedule in patients with advanced solid tumors.
- Conditions
- Advanced Solid Tumor Cancers, Medulloblastoma, Basal Cell Carcinoma
- Trial name
- NCT00880308
- Testing
- LDE225
- Where
- 5 sites in United States, Spain and 2 more
- Volunteers
- 103 people
- Sponsor
- Novartis Pharmaceuticals
Field Actinic Keratoses, Basal Cell Carcinoma
Compassionate Use of Metvix® (Methyl Aminolevulinate) Photodynamic Therapy (PDT) in Subjects With Field Actinic Keratoses, Large/Multiple Superficial Basal Cell Carcinomas (BCCs), or Bowen's Disease
The aim of this study is to provide this investigational drug to patients who cannot be optimally treated with conventional therapies and to collect efficacy and safety data on the use of Metvix PDT in subjects with field actinic…
- Conditions
- Field Actinic Keratoses, Basal Cell Carcinoma, Bowen's Disease
- Trial name
- NCT00535080
- Testing
- Metvix (methyl aminolevulinate)
- Sponsor
- Galderma R&D
Basal Cell Carcinoma
Periocular Basal Cell Carcinoma (BCC): Permanent vs. Frozen Section Pathological Control
This study is an equivalency study designed as a randomized clinical trial. Patients with a biopsy proven nodular periocular basal cell carcinoma (BCC) who have agreed to have surgical excision will be eligible.
- Trial name
- NCT00663650
- Testing
- Permanent Section Control, Frozen Section Control
- Where
- Canada
- Volunteers
- 290 people
- Sponsor
- Queen's University
Basal Cell Carcinoma
RCM to Diagnose BCC - Reflectance Confocal Microscopy to Diagnose Basal Cell Carcinoma
Basal cell carcinoma (BCC) is the commonest non melanoma skin cancer in the UK and its incidence is rising. The Norfolk and Norwich University Hospital Foundation Trust (NNUHFT) see and excise approximately 3,000 new cases of BCC…
- Trial name
- RCM-1 (NCT03331874)
- Testing
- Reflectance Confocal Microscopy
- Where
- United Kingdom
- Volunteers
- 352 people
- Sponsor
- Julie Dawson
Basal Cell Carcinoma
Basal Cell Carcinoma Chemoprevention Trial
This is an intent-to-treat, parallel design, multicenter randomized trial and the primary intervention is a double-blind comparison of imiquimod (IMQ) vs.
- Trial name
- B3C (NCT05212246)
- Testing
- 5% Imiquimod cream
- Where
- 8 sites in United States
- Volunteers
- 1,630 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Basal Cell Carcinoma
Clinical Diagnosis of Basal Cell Carcinoma Subtype
Skin cancer is the most common cancer in Caucasians. Basal cell carcinoma (BCC) is the most frequent skin cancer with around 44.000 new tumours per year in the Netherlands, and its incidence is still rising.
- Trial name
- NCT01370824
- Testing
- Punch biopsy, Surgical excision
- Where
- 2 sites in Netherlands
- Volunteers
- 150 people
- Sponsor
- Maastricht University Medical Center
Non-melanoma Skin Cancer, Squamous Cell Carcinoma of Skin
Same-day Versus Separate-day Preoperative Consultation for Mohs Surgery
The purpose of this study is to determine whether separate- versus same-day preoperative consultation affects time to treatment (start to finish), utilization rate of Mohs, rate of case cancellations, cost, and patient…
- Conditions
- Non-melanoma Skin Cancer, Squamous Cell Carcinoma of Skin, Basal Cell Carcinoma
- Trial name
- NCT02321982
- Testing
- Same-day preoperative consultation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Skin Cancer, Basal Cell Carcinoma
Correlation Between Skin Carotenoid Levels and Previous History of Skin Cancer
The purpose of this study is to determine the difference of skin carotenoid levels between subjects with previous squamous cell carcinomas (SCC), subjects with previous basal cell carcinomas (BCC) and a control group.
- Conditions
- Skin Cancer, Basal Cell Carcinoma, Squamous Cell Carcinoma
- Trial name
- NCT00836342
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Skin Lesions, Melanocytic Nevi
Evaluating an Artificial Intelligence Tool to Help Primary Care Doctors Diagnose Skin Conditions.
This study aims to determine if an artificial intelligence (AI) medical device can help primary care doctors more accurately identify and manage various skin conditions.
- Conditions
- Skin Lesions, Melanocytic Nevi, Melanoma (Skin Cancer), Basal Cell Carcinoma of Skin
- Trial name
- LegitHealth PH (NCT07428941)
- Testing
- AI-based medical device for aided diagnosis in dermatological conditions
- Where
- Spain
- Volunteers
- 9 people
- Sponsor
- AI Labs Group S.L
Basal Cell Cancer, Grafting
Investigating the Effects of Orienting Skin Grafts Parallel to Skin Tension Lines on Quality of Life in Head and Neck Located Basal Cell Carcinoma
The goal of this observational study is to learn about the effect of orienting graft for treatment of skin cancer in patients who undergo skin cancer excision and grafting for their skin cancer.
- Trial name
- NCT06894056
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people
- Sponsor
- Sifa Okulu - Independent Research Center of Dermatology and Venereology
Non-melanomatous Skin Cancer, Precancerous Condition
Photodynamic Therapy in Treating Patients With Skin Cancer
RATIONALE: Photodynamic therapy uses light and drugs that make cancer cells more sensitive to light to kill tumor cells. Photodynamic therapy using aminolevulinic acid may be effective in treating patients with skin cancer.
- Trial name
- NCT00002975
- Testing
- aminolevulinic acid
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Roswell Park Cancer Institute
Adenocarcinoma, Basal Cell Carcinoma
Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors
This is a pilot clinical trial determining the effect of a Methionine-reduced diet on serum levels in subjects with solid tumors. These are subjects who will receive systemic standard of care cancer therapy.
- Conditions
- Adenocarcinoma, Basal Cell Carcinoma, Squamous Cell Carcinoma, Transitional Cell Carcinoma
- Trial name
- NCT07628634
- Testing
- Methionine-Reduced Diet
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, Irvine
Bowen's Disease, Superficial Basal Cell Carcinoma
Laser Assisted Drug Delivery in the Treatment of Superficial Non Melanoma Skin Cancer: a Randomized Controlled Trial
Photodynamic therapy (PDT) is a well established treatment option for superficial non melanoma skin cancer, such as superficial basal cell carcinoma (sBCC) and Bowen Disease (BD).
- Trial name
- NCT03012009
- Testing
- full ablative CO2 laser, fractional ablative CO2 laser, MAL
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- University Hospital, Ghent
Basal Cell Carcinoma
Observational Study of Vismodegib (Erivedge) in Patients Treated in Argentina
This observational, noninterventional study is designed to further characterize the effectiveness and safety profile of vismodegib (Erivedge) in Argentine patients.
- Trial name
- NCT02438644
- Volunteers
- 75 people
- Sponsor
- Hoffmann-La Roche